{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T18:42:12Z","timestamp":1792694532862,"version":"4.5.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T00:00:00Z","timestamp":1754438400000},"content-version":"vor","delay-in-days":370,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.jacc.2024.05.004","type":"journal-article","created":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T04:08:39Z","timestamp":1715659719000},"page":"512-521","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["The Influence of Epicardial Resistance on Microvascular Resistance Reserve"],"prefix":"10.1016","volume":"84","author":[{"given":"Thabo","family":"Mahendiran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dario","family":"Bertolone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele Mattia","family":"Viscusi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5519-2818","authenticated-orcid":false,"given":"Emanuele","family":"Gallinoro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle C.J.","family":"Keulards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Collet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen","family":"Sonck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriaan","family":"Wilgenhof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nico H.J.","family":"Pijls","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"De Bruyne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2024.05.004_bib1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.ijcard.2017.08.068","article-title":"International standardization of diagnostic criteria for microvascular angina","volume":"250","author":"Ong","year":"2018","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jacc.2024.05.004_bib2","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1161\/hc4501.099316","article-title":"Abnormal epicardial coronary resistance in patients with diffuse atherosclerosis but \u201cNormal\u201d coronary angiography","volume":"104","author":"De Bruyne","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2024.05.004_bib3","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.jacc.2011.09.077","article-title":"Functional measurement of coronary stenosis","volume":"59","author":"Pijls","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2024.05.004_bib4","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1161\/CIRCINTERVENTIONS.109.904193","article-title":"Reduction in myocardial perfusion territory and its effect on the physiological severity of a coronary stenosis","volume":"3","author":"Iqbal","year":"2010","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jacc.2024.05.004_bib5","doi-asserted-by":"crossref","first-page":"2396","DOI":"10.1016\/j.jcin.2023.08.018","article-title":"Impact of post-PCI FFR stratified by coronary artery","volume":"16","author":"Collet","year":"2023","journal-title":"JACC Cadiovasc Interv"},{"key":"10.1016\/j.jacc.2024.05.004_bib6","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1016\/j.jacc.2021.08.017","article-title":"Microvascular resistance reserve for assessment of coronary microvascular function: JACC technology corner","volume":"78","author":"De Bruyne","year":"2021","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2024.05.004_bib7","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/j.jacc.2023.12.014","article-title":"Measuring absolute coronary flow and microvascular resistance by thermodilution: JACC review topic of the week","volume":"83","author":"Belmonte","year":"2024","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2024.05.004_bib8","doi-asserted-by":"crossref","first-page":"2862","DOI":"10.1093\/eurheartj\/ehad378","article-title":"Microvascular resistance reserve: diagnostic and prognostic performance in the ILIAS registry","volume":"44","author":"Boerhout","year":"2023","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2024.05.004_bib9","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.jacc.2021.08.028","article-title":"Assessing microvascular dysfunction in angina with unobstructed coronary arteries","volume":"78","author":"Jansen","year":"2021","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2024.05.004_bib10","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1016\/j.jacc.2018.09.006","article-title":"Stratified medical therapy using invasive coronary function testing in angina","volume":"72","author":"Ford","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2024.05.004_bib11","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jcin.2019.11.001","article-title":"1-year outcomes of angina management guided by invasive coronary function testing (CorMicA)","volume":"13","author":"Ford","year":"2020","journal-title":"JACC Cadiovasc Interv"},{"key":"10.1016\/j.jacc.2024.05.004_bib12","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0002-9149(74)90743-7","article-title":"Physiologic basis for assessing critical coronary stenosis. Instantaneous flow response and regional distribution during coronary hyperemia as measures of coronary flow reserve","volume":"33","author":"Gould","year":"1974","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2024.05.004_bib13","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.ehj.2003.11.009","article-title":"Validation of coronary flow reserve measurements by thermodilution in clinical practice","volume":"25","author":"Barbato","year":"2004","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2024.05.004_bib14","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1161\/hc4201.099223","article-title":"Coronary thermodilution to assess\u00a0flow reserve","volume":"104","author":"De Bruyne","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2024.05.004_bib15","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.1161\/01.CIR.0000017199.09457.3D","article-title":"Coronary thermodilution to assess flow reserve","volume":"105","author":"Pijls","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2024.05.004_bib16","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.jcin.2022.12.012","article-title":"Microvascular resistance reserve to assess microvascular dysfunction in ANOCA patients","volume":"16","author":"de Vos","year":"2023","journal-title":"JACC Cadiovasc Interv"},{"key":"10.1016\/j.jacc.2024.05.004_bib17","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1016\/j.jcin.2023.09.027","article-title":"Continuous vs bolus thermodilution to assess microvascular resistance reserve","volume":"16","author":"Gallinoro","year":"2023","journal-title":"JACC Cadiovasc Interv"},{"key":"10.1016\/j.jacc.2024.05.004_bib18","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1161\/CIRCULATIONAHA.119.041595","article-title":"Coronary microvascular dysfunction is associated with myocardial ischemia and abnormal coronary perfusion during exercise","volume":"140","author":"Rahman","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2024.05.004_bib19","doi-asserted-by":"crossref","first-page":"3129","DOI":"10.1161\/01.CIR.0000080700.98607.D1","article-title":"Novel index for invasively assessing the coronary microcirculation","volume":"107","author":"Fearon","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2024.05.004_bib20","doi-asserted-by":"crossref","first-page":"2030","DOI":"10.1056\/NEJMc2402216","article-title":"Coronary\u2013artery autoregulation with increasing stenosis","volume":"390","author":"Mahendiran","year":"2024","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2024.05.004_bib21","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/j.jacc.2018.12.052","article-title":"Hyperemic pressure-flow relationship in a human","volume":"73","author":"Fournier","year":"2019","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2024.05.004_bib22","article-title":"Continuous versus bolus thermodilution-derived coronary flow reserve and microvascular resistance reserve and their association with angina and quality of life in patients with angina and nonobstructive coronaries: a head-to-head comparison","volume":"12","author":"Jansen","year":"2023","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.jacc.2024.05.004_bib23","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.117.006194","article-title":"Catheter-based measurements of absolute coronary blood flow and microvascular resistance: feasibility, safety, and reproducibility in humans","volume":"11","author":"Xaplanteris","year":"2018","journal-title":"Circ Cardiovasc Interv"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109724071985?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109724071985?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T01:24:11Z","timestamp":1754443451000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109724071985"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":23,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["S0735109724071985"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2024.05.004","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Influence of Epicardial Resistance on Microvascular Resistance Reserve","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2024.05.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}