{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T03:32:56Z","timestamp":1793158376341,"version":"4.5.0"},"reference-count":9,"publisher":"Elsevier BV","issue":"17","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T00:00:00Z","timestamp":1793145600000},"content-version":"vor","delay-in-days":392,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.jacc.2025.06.009","type":"journal-article","created":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T03:02:01Z","timestamp":1760670121000},"page":"1389-1391","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Retinal Fundus Verdict on Intensive Blood-Pressure Therapy"],"prefix":"10.1016","volume":"86","author":[{"given":"Mathieu F.","family":"Bakhoum","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael K.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina J.","family":"Jayaraj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael H.","family":"Goldbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine Y.","family":"Bakhoum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2025.06.009_bib1","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1056\/NEJMoa1511939","article-title":"A randomized trial of intensive versus standard blood-pressure control","volume":"373","author":"Wright","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2025.06.009_bib2","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1056\/NEJMoa1600175","article-title":"Blood-pressure lowering in intermediate-risk persons without cardiovascular disease","volume":"374","author":"Yusuf","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2025.06.009_bib3","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0140-6736(24)01028-6","article-title":"Lowering systolic blood pressure to less than 120 mm Hg versus less than 140 mm Hg in patients with high cardiovascular risk with and without diabetes or previous stroke: an open-label, blinded-outcome, randomised trial","volume":"404","author":"Liu","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2025.06.009_bib4","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/s41569-024-01060-8","article-title":"Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a roadmap from an NHLBI workshop","volume":"22","author":"Chew","year":"2025","journal-title":"Nat Rev Cardiol"},{"issue":"17","key":"10.1016\/j.jacc.2025.06.009_bib5","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1016\/j.jacc.2025.05.020","article-title":"Effect of intensive blood pressure lowering treatment on retinal microvasculature: Secondary analysis from ESPRIT","volume":"86","author":"Wang","year":"2025","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2025.06.009_bib6","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1161\/CIRCULATIONAHA.116.023425","article-title":"Retinal vessel calibers in predicting long-term cardiovascular outcomes: the ARIC study","volume":"134","author":"Seidelmann","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2025.06.009_bib7","doi-asserted-by":"crossref","first-page":"3245","DOI":"10.1161\/STROKEAHA.112.673335","article-title":"Retinal microvascular signs and risk of stroke in a multi-ethnic cohort: the MESA","volume":"43","author":"Kawasaki","year":"2012","journal-title":"Stroke"},{"key":"10.1016\/j.jacc.2025.06.009_bib8","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1167\/tvst.13.1.2","article-title":"Retinal vascular measurements and mortality risk: evidence from the UK Biobank study","volume":"13","author":"Shi","year":"2024","journal-title":"Transl Vis Sci Technol"},{"key":"10.1016\/j.jacc.2025.06.009_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2021.100775","article-title":"Prevalence of subclinical retinal ischemia in patients with cardiovascular disease:a hypothesis driven study","volume":"33","author":"Long","year":"2021","journal-title":"EClinicalMed"}],"container-title":["JACC"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109725067762?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109725067762?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T02:43:47Z","timestamp":1793155427000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109725067762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":9,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S0735109725067762"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2025.06.009","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Retinal Fundus Verdict on Intensive Blood-Pressure Therapy","name":"articletitle","label":"Article Title"},{"value":"JACC","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2025.06.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2025.05.020","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}