{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T12:11:14Z","timestamp":1793880674914,"version":"4.7.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"17","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,5,5]],"date-time":"2027-05-05T00:00:00Z","timestamp":1809475200000},"content-version":"am","delay-in-days":369,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Swiss National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000038","name":"U.S. Food and Drug Administration","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.jacc.2025.11.043","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T15:08:25Z","timestamp":1765379305000},"page":"2282-2297","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Cardiovascular Risk Across Myocardial Injury and Infarction Categories Using the Universal Definition"],"prefix":"10.1016","volume":"87","author":[{"given":"Jasper","family":"Boeddinghaus","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Lopez-Ayala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander J.F.","family":"Thurston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuan Ken","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Yong","family":"Tew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Doudesis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Kadesj\u00f6","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Roos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire E.","family":"Raphael","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yader","family":"Sandoval","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajiv","family":"Gulati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7379-5439","authenticated-orcid":false,"given":"Caelan","family":"Taggart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6485-453X","authenticated-orcid":false,"given":"Ryan","family":"Wereski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Koechlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6428-4554","authenticated-orcid":false,"given":"Atul","family":"Anand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Mahfoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes T.","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Strau\u00df","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils A.","family":"S\u00f6rensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathaniel R.","family":"Smilowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David E.","family":"Newby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan","family":"Jaffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas L.","family":"Mills","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catalina A.","family":"Vallejos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1926-5925","authenticated-orcid":false,"given":"Andrew R.","family":"Chapman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Nestelberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emel","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lourdes Herraiz","family":"Recuenco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle","family":"Hur\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Bima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Wildi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d2scar","family":"Mir\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Christ","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dagmar I.","family":"Keller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli\u0161ka","family":"Potlukov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damian","family":"Kawecki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beata","family":"Morawiec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiri","family":"Parenica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier F.","family":"Martin-Sanchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivo","family":"Strebel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul M.","family":"Haller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas","family":"Lehmacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bet\u00fcl","family":"Toprak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael","family":"Twerenbold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas L.","family":"Mills","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona E.","family":"Strachan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Tuck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atul","family":"Anand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Barker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Blades","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasper","family":"Boeddinghaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anda","family":"Bularga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew R.","family":"Chapman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Doudesis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy V.","family":"Ferry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Fujisawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantin","family":"Georgiev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziwen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorien M.","family":"Kimenai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuan Ken","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew TH.","family":"Lowry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"McKinlay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"McDermott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"McPherson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filip","family":"Mendusic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas L.","family":"Mills","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anoop SV.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Sorbie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"Souter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey D.","family":"Schulberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caelan","family":"Taggart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Tuck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel Perez","family":"Vicencio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiqing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Wereski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas L.","family":"Mills","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David E.","family":"Newby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith A.A.","family":"Fox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin","family":"Berry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Weir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Ford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas L.","family":"Mills","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David E.","family":"Newby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alasdair","family":"Gray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith A.A.","family":"Fox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin","family":"Berry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul O.","family":"Collinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred S.","family":"Apple","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Reid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Cruikshank","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iain","family":"Findlay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Amoils","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"McAllister","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donogh","family":"Maguire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Stevens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Norrie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Weir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anoop S.V.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atul","family":"Anand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew R.","family":"Chapman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuan Ken","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack P.M.","family":"Andrews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip D.","family":"Adamson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alastair","family":"Moss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed S.","family":"Anwar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Hung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas L.","family":"Mills","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Malo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Reid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Cruikshank","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul O.","family":"Collinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin M.","family":"Fischbacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard L.","family":"Croal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Leslie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catriona","family":"Keerie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard A.","family":"Parker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan","family":"Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronnie","family":"Harkess","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Tuck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"Wackett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Weir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roma","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Stirling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"MacDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imran","family":"Sadat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Finlay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Charles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela","family":"Linksted","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bill","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Duncan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Slusser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"20","key":"10.1016\/j.jacc.2025.11.043_bib1","doi-asserted-by":"crossref","first-page":"e618","DOI":"10.1161\/CIR.0000000000000617","article-title":"Fourth universal definition of myocardial infarction (2018)","volume":"138","author":"Thygesen","year":"2018","journal-title":"Circulation"},{"issue":"22","key":"10.1016\/j.jacc.2025.11.043_bib2","doi-asserted-by":"crossref","first-page":"2634","DOI":"10.1161\/CIRCULATIONAHA.107.187397","article-title":"Universal definition of myocardial infarction","volume":"116","author":"Thygesen","year":"2007","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.jacc.2025.11.043_bib3","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1093\/eurheartj\/ehae803","article-title":"Type 2 myocardial infarction: challenges in diagnosis and treatment","volume":"46","author":"Chapman","year":"2025","journal-title":"Eur Heart J"},{"issue":"12","key":"10.1016\/j.jacc.2025.11.043_bib4","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1161\/CIRCULATIONAHA.117.031806","article-title":"Long-term outcomes in patients with type 2 myocardial infarction and myocardial injury","volume":"137","author":"Chapman","year":"2018","journal-title":"Circulation"},{"issue":"18","key":"10.1016\/j.jacc.2025.11.043_bib5","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1136\/heartjnl-2021-319118","article-title":"Sex differences in investigations and outcomes among patients with type 2 myocardial infarction","volume":"107","author":"Kimenai","year":"2021","journal-title":"Heart"},{"issue":"2","key":"10.1016\/j.jacc.2025.11.043_bib6","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1093\/eurheartj\/ehab581","article-title":"Risk factors for type 1 and type 2 myocardial infarction","volume":"43","author":"Wereski","year":"2022","journal-title":"Eur Heart J"},{"issue":"5","key":"10.1016\/j.jacc.2025.11.043_bib7","article-title":"Targeting investigation and treatment in type 2 myocardial infarction: a pilot randomized controlled trial","volume":"4","author":"Taggart","year":"2025","journal-title":"JACC: Adv"},{"key":"10.1016\/j.jacc.2025.11.043_bib8","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1016\/j.jacc.2023.08.020","article-title":"Coronary computed tomographic angiography with fractional flow reserve in patients with type 2 myocardial infarction","volume":"82","author":"McCarthy","year":"2023","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.jacc.2025.11.043_bib9","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1161\/CIRCULATIONAHA.119.042960","article-title":"High-sensitivity cardiac troponin and the universal definition of myocardial infarction","volume":"141","author":"Chapman","year":"2020","journal-title":"Circulation"},{"issue":"13","key":"10.1016\/j.jacc.2025.11.043_bib10","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1016\/j.jacc.2017.07.774","article-title":"Effect of definition on incidence and prognosis of type 2 myocardial infarction","volume":"70","author":"Nestelberger","year":"2017","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"10.1016\/j.jacc.2025.11.043_bib11","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1161\/CIRCULATIONAHA.116.023052","article-title":"Incident type 2 myocardial infarction in a cohort of patients undergoing coronary or peripheral arterial angiography","volume":"135","author":"Gaggin","year":"2017","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.jacc.2025.11.043_bib12","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1161\/CIRCULATIONAHA.111.041160","volume":"125","author":"Bonaca","year":"2012","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.jacc.2025.11.043_bib13","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1161\/CIRCULATIONAHA.119.043100","article-title":"Incidence, trends, and outcomes of type 2 myocardial infarction in a community cohort","volume":"141","author":"Raphael","year":"2020","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.jacc.2025.11.043_bib14","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1001\/jamacardio.2022.0043","article-title":"Characteristics and outcomes of type 2 myocardial infarction","volume":"7","author":"Coscia","year":"2022","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jacc.2025.11.043_bib15","doi-asserted-by":"crossref","first-page":"3514","DOI":"10.1093\/eurheartj\/ehx457","article-title":"Discrimination of patients with type 2 myocardial infarction","volume":"38","author":"Neumann","year":"2017","journal-title":"Eur Heart J"},{"issue":"4","key":"10.1016\/j.jacc.2025.11.043_bib16","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.5853","article-title":"Application of the universal definition of myocardial infarction in clinical practice in Scotland and Sweden","volume":"7","author":"Taggart","year":"2024","journal-title":"JAMA Netw Open"},{"issue":"9","key":"10.1016\/j.jacc.2025.11.043_bib17","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.jacc.2019.12.052","article-title":"Cardiovascular mortality after type 1 and type 2 myocardial infarction in young adults","volume":"75","author":"Singh","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2025.11.043_bib18","series-title":"Cochrane Handbook for Systematic Reviews of Interventions version 6.5 (updated August 2024)","year":"2024"},{"issue":"3","key":"10.1016\/j.jacc.2025.11.043_bib19","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/jrsm.45","article-title":"Individual patient data meta-analysis of time-to-event outcomes: one-stage vs two-stage approaches for estimating the hazard ratio under a random effects model","volume":"2","author":"Bowden","year":"2011","journal-title":"Res Synth Methods"},{"key":"10.1016\/j.jacc.2025.11.043_bib20","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1080\/01621459.1999.10474144","article-title":"A proportional hazards model for the subdistribution of a competing risk","volume":"94","author":"Fine","year":"1999","journal-title":"J Am Stat Assoc"},{"issue":"7414","key":"10.1016\/j.jacc.2025.11.043_bib21","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"issue":"3","key":"10.1016\/j.jacc.2025.11.043_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v036.i03","article-title":"Conducting meta-analyses in R with the metafor package","volume":"36","author":"Viechtbauer","year":"2010","journal-title":"J Stat Softw"},{"issue":"25","key":"10.1016\/j.jacc.2025.11.043_bib23","doi-asserted-by":"crossref","first-page":"3160","DOI":"10.1016\/j.jacc.2021.04.050","article-title":"Clinical impact of high-sensitivity cardiac troponin t implementation in the community","volume":"77","author":"Ola","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2025.11.043_bib24","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/S0140-6736(18)31923-8","article-title":"High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial","volume":"392","author":"Shah","year":"2018","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.jacc.2025.11.043_bib25","first-page":"62","article-title":"Direct comparison of high-sensitivity cardiac troponin T and I in the early differentiation of type 1 vs. type 2 myocardial infarction","volume":"11","author":"Nestelberger","year":"2022","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"issue":"9","key":"10.1016\/j.jacc.2025.11.043_bib26","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3390\/biom9090469","article-title":"Prognostic value of a novel and established high-sensitivity troponin i assay in patients presenting with suspected myocardial infarction","volume":"9","author":"S\u00f6rensen","year":"2019","journal-title":"Biomolecules"},{"issue":"23","key":"10.1016\/j.jacc.2025.11.043_bib27","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1161\/CIRCULATIONAHA.120.052380","article-title":"High-sensitivity cardiac troponin on presentation to rule out myocardial infarction: a stepped-wedge cluster randomized controlled trial","volume":"143","author":"Anand","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2025.11.043_bib28","first-page":"546","article-title":"Major adverse cardiovascular events after diagnosis of myocardial injury and types 1 and 2 myocardial infarction","volume":"11","author":"Knott","year":"2022","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"issue":"24","key":"10.1016\/j.jacc.2025.11.043_bib29","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1136\/heartjnl-2019-315036","article-title":"Acute versus chronic myocardial injury and long-term outcomes","volume":"105","author":"Kadesj\u00f6","year":"2019","journal-title":"Heart"},{"issue":"1","key":"10.1016\/j.jacc.2025.11.043_bib30","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1097\/MCA.0000000000000545","article-title":"Treatment and outcomes of type 2 myocardial infarction and myocardial injury compared with type 1 myocardial infarction","volume":"29","author":"Smilowitz","year":"2018","journal-title":"Coron Artery Dis"},{"issue":"20","key":"10.1016\/j.jacc.2025.11.043_bib31","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1161\/CIRCULATIONAHA.119.040631","article-title":"Assessment and treatment of patients with type 2 myocardial infarction and acute nonischemic myocardial injury","volume":"140","author":"DeFilippis","year":"2019","journal-title":"Circulation"},{"issue":"21","key":"10.1016\/j.jacc.2025.11.043_bib32","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1136\/heartjnl-2014-307122","article-title":"Type 2 myocardial infarction: the chimaera of cardiology?","volume":"101","author":"Collinson","year":"2015","journal-title":"Heart"},{"issue":"11","key":"10.1016\/j.jacc.2025.11.043_bib33","first-page":"675","article-title":"Cardiovascular and non-cardiovascular mortality at 5 years in patients with type 1 and type 2 myocardial infarction","volume":"14","author":"Taggart","year":"2025","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"issue":"4","key":"10.1016\/j.jacc.2025.11.043_bib34","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.amjmed.2015.11.035","article-title":"Impact on long-term mortality of presence of obstructive coronary artery disease and classification of myocardial infarction","volume":"129","author":"Baron","year":"2016","journal-title":"Am J Med"},{"issue":"1","key":"10.1016\/j.jacc.2025.11.043_bib35","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/clinchem\/hvaa189","article-title":"Type 2 myocardial infarction: evolving approaches to diagnosis and risk-stratification","volume":"67","author":"Chapman","year":"2021","journal-title":"Clin Chem"},{"key":"10.1016\/j.jacc.2025.11.043_bib36","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.jcmg.2011.12.016","article-title":"Angiographic correlates in type 1 and 2 MI by the universal definition","volume":"5","author":"Ambrose","year":"2012","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.jacc.2025.11.043_bib37","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.125.042858","article-title":"Identification of clinical phenotype in type 2 myocardial infarction: insights into characteristics, prognosis and management strategies","volume":"14","author":"Bertolini","year":"2025","journal-title":"J Am Heart Assoc"},{"issue":"14","key":"10.1016\/j.jacc.2025.11.043_bib38","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1016\/j.jacc.2019.02.018","article-title":"Type 2 Myocardial infarction: JACC review topic of the week","volume":"73","author":"Sandoval","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"10.1016\/j.jacc.2025.11.043_bib39","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1136\/heartjnl-2014-306093","article-title":"Type 2 myocardial infarction in clinical practice","volume":"101","author":"Baron","year":"2015","journal-title":"Heart"},{"issue":"12","key":"10.1016\/j.jacc.2025.11.043_bib40","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/j.amjmed.2017.05.049","article-title":"Type 1 and 2 myocardial infarction and myocardial injury: clinical transition to high-sensitivity cardiac troponin I","volume":"130","author":"Sandoval","year":"2017","journal-title":"Am J Med"},{"issue":"4","key":"10.1016\/j.jacc.2025.11.043_bib41","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.amjmed.2013.12.020","article-title":"Mortality rate in type 2 myocardial infarction: observations from an unselected hospital cohort","volume":"127","author":"Saaby","year":"2014","journal-title":"Am J Med"},{"key":"10.1016\/j.jacc.2025.11.043_bib42","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.jacc.2017.12.048","article-title":"2017 cardiovascular and stroke endpoint definitions for clinical trials","volume":"71","author":"Hicks","year":"2018","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.jacc.2025.11.043_bib43","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1177\/2047487312450228","volume":"19","author":"Perk","year":"2012","journal-title":"Eur J Prevent Cardiol"},{"issue":"3","key":"10.1016\/j.jacc.2025.11.043_bib44","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1161\/01.cir.0000442015.53336.12","article-title":"Executive summary: heart disease and stroke statistics--2014 update: a report from the American Heart Association","volume":"129","author":"Go","year":"2014","journal-title":"Circulation"}],"container-title":["JACC"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109725103483?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109725103483?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T10:06:29Z","timestamp":1778753189000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109725103483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":44,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S0735109725103483"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2025.11.043","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cardiovascular Risk Across Myocardial Injury and Infarction Categories Using the Universal Definition","name":"articletitle","label":"Article Title"},{"value":"JACC","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2025.11.043","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}