{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T01:23:29Z","timestamp":1793237009925,"version":"4.5.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"17","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016015","name":"Universitatsspital Basel","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016015","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.jacc.2025.12.052","type":"journal-article","created":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T16:18:06Z","timestamp":1774455486000},"page":"2236-2257","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["High-Sensitivity Cardiac Troponin T-gen6 Assay in Suspected Myocardial Infarction"],"prefix":"10.1016","volume":"87","author":[{"given":"Luca","family":"Koechlin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Lopez-Ayala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander J.F.","family":"Thurston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Yong","family":"Tew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"O\u2019Brien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alasdair","family":"Gray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2193-0509","authenticated-orcid":false,"given":"Paolo","family":"Bima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0536-6922","authenticated-orcid":false,"given":"Emel","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d2scar","family":"Mir\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Christ","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dagmar I.","family":"Keller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier F.","family":"Martin-Sanchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beata","family":"Morawiec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiri","family":"Parenica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6511-7619","authenticated-orcid":false,"given":"Lourdes","family":"Herraiz Recuenco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle","family":"Hur\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Wildi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Crisanti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3481-7666","authenticated-orcid":false,"given":"Carlos","family":"Spagnuolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3606-0893","authenticated-orcid":false,"given":"Jonas","family":"Glaeser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Caubergh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Rentsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ksenija","family":"Slankamenac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9ctor","family":"Rodriguez Cetina Biefer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omer","family":"Dzemali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivo","family":"Strebel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4425-549X","authenticated-orcid":false,"given":"Felix","family":"Mahfoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas L.","family":"Mills","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasper","family":"Boeddinghaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Nestelberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desiree","family":"Wussler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Rubini Gimenez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jude","family":"Formambuh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Zimmermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle M.","family":"Gualandro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Puelacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne","family":"du Fay de Lavallaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Reinhardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"Meissner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gemma","family":"Martinez-Nadal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther Rodriguez","family":"Adrada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnold","family":"von Eckardstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damian","family":"Kawecki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Muzyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Geigy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli\u0161ka","family":"Potlukov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Steuer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelika","family":"Hammerer-Lercher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Buser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Fujisawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Tuck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Highton-Williamson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona","family":"McCurrach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Lynch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Cheyne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie G.","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirley","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Coutts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onyinyechi","family":"Oziogu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Noble","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mizu","family":"Mizerska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy V.","family":"Ferry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziwen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel P.","family":"Vicencio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caelan","family":"Taggart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"McDermott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Wereski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Blades","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salan","family":"Rowlands","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Sorbie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorien","family":"Kimenai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David E.","family":"Newby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"38","key":"10.1016\/j.jacc.2025.12.052_bib1","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1093\/eurheartj\/ehad191","article-title":"2023 ESC guidelines for the management of acute coronary syndromes","volume":"44","author":"Byrne","year":"2023","journal-title":"Eur Heart J"},{"issue":"22","key":"10.1016\/j.jacc.2025.12.052_bib2","doi-asserted-by":"crossref","first-page":"e187","DOI":"10.1016\/j.jacc.2021.07.053","article-title":"2021 AHA\/ACC\/ASE\/CHEST\/SAEM\/SCCT\/SCMR guideline for the evaluation and diagnosis of chest pain: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"78","author":"Gulati","year":"2021","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.jacc.2025.12.052_bib3","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1093\/clinchem\/hvaa226","article-title":"Early rule-out strategies in the emergency department utilizing high-sensitivity cardiac troponin assays","volume":"67","author":"Lopez-Ayala","year":"2021","journal-title":"Clin Chem"},{"issue":"22","key":"10.1016\/j.jacc.2025.12.052_bib4","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1016\/j.jacc.2024.11.009","article-title":"2025 ACC\/AHA\/ACEP\/NAEMSP\/SCAI guideline for the management of patients with acute coronary syndromes: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"85","author":"Rao","year":"2025","journal-title":"J Am Coll Cardiol"},{"issue":"12","key":"10.1016\/j.jacc.2025.12.052_bib8","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1016\/j.jacc.2017.07.746","article-title":"Effect of the FDA regulatory approach on the 0\/1-h algorithm for rapid diagnosis of MI","volume":"70","author":"Twerenbold","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2025.12.052_bib9","doi-asserted-by":"crossref","unstructured":"Knoll M, Daniels LB, Mueller C, et al. Analytical performance evaluation of the cardiac troponin T high sensitivity Gen 6 assay. Rev Clin Chem. https:\/\/doi.org\/10.1093\/jalm\/jfag031","DOI":"10.1093\/jalm\/jfag031"},{"key":"10.1016\/j.jacc.2025.12.052_bib10","article-title":"Establishing reference values in healthy participants for the cardiac troponin T high-sensitivity gen 6 assay: REF-TSIX Global Reference Study","volume":"hvag011","author":"Daniels","year":"2026","journal-title":"Clin Chem"},{"issue":"9","key":"10.1016\/j.jacc.2025.12.052_bib11","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1056\/NEJMoa0900428","article-title":"Early diagnosis of myocardial infarction with sensitive cardiac troponin assays","volume":"361","author":"Reichlin","year":"2009","journal-title":"N Engl J Med"},{"issue":"10","key":"10.1016\/j.jacc.2025.12.052_bib12","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1161\/CIRCULATIONAHA.120.052982","article-title":"Novel criteria for the observe-zone of the ESC 0\/1h-hs-cTnT algorithm","volume":"144","author":"Lopez-Ayala","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2025.12.052_bib13","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.ahj.2023.11.014","article-title":"External validation of the 0\/1h-algorithm and derivation of a 0\/2h-algorithm using a new point-of-care Hs-cTnI assay","volume":"268","author":"Koechlin","year":"2024","journal-title":"Am Heart J"},{"issue":"2","key":"10.1016\/j.jacc.2025.12.052_bib14","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1093\/clinchem\/hvab203","article-title":"0\/2 h-algorithm for rapid triage of suspected myocardial infarction using a novel high-sensitivity cardiac troponin I assay","volume":"68","author":"Wildi","year":"2022","journal-title":"Clin Chem"},{"key":"10.1016\/j.jacc.2025.12.052_bib15","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ahj.2022.10.007","article-title":"Diagnostic discrimination of a novel high-sensitivity cardiac troponin I assay and derivation\/validation of an assay-specific 0\/1h-algorithm","volume":"255","author":"Koechlin","year":"2023","journal-title":"Am Heart J"},{"issue":"18","key":"10.1016\/j.jacc.2025.12.052_bib16","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1016\/j.jacc.2018.08.1038","article-title":"Executive Group on behalf of the Joint ESC\/ACC\/AHA\/WHF Task Force for the Universal Definition of Myocardial Infarction. Fourth universal definition of myocardial infarction (2018)","volume":"72","author":"Thygesen","year":"2018","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"10.1016\/j.jacc.2025.12.052_bib17","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1373\/clinchem.2009.132654","article-title":"Analytical validation of a high-sensitivity cardiac troponin T assay","volume":"56","author":"Giannitsis","year":"2010","journal-title":"Clin Chem"},{"issue":"8","key":"10.1016\/j.jacc.2025.12.052_bib18","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.jacc.2024.05.056","article-title":"Clinical and analytical performance of a novel point-of-care high-sensitivity cardiac troponin I assay","volume":"84","author":"Koechlin","year":"2024","journal-title":"J Am Coll Cardiol"},{"issue":"10","key":"10.1016\/j.jacc.2025.12.052_bib19","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/j.jacc.2019.12.065","article-title":"Early diagnosis of myocardial infarction with point-of-care high-sensitivity cardiac troponin I","volume":"75","author":"Boeddinghaus","year":"2020","journal-title":"J Am Coll Cardiol"},{"issue":"8476","key":"10.1016\/j.jacc.2025.12.052_bib20","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0140-6736(86)90837-8","article-title":"Statistical methods for assessing agreement between two methods of clinical measurement","volume":"1","author":"Bland","year":"1986","journal-title":"Lancet"},{"issue":"30","key":"10.1016\/j.jacc.2025.12.052_bib21","doi-asserted-by":"crossref","first-page":"5381","DOI":"10.1002\/sim.5958","article-title":"Estimating and comparing time-dependent areas under receiver operating characteristic curves for censored event times with competing risks","volume":"32","author":"Blanche","year":"2013","journal-title":"Stat Med"},{"issue":"22","key":"10.1016\/j.jacc.2025.12.052_bib22","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1136\/heartjnl-2019-315084","article-title":"Convalescent troponin and cardiovascular death following acute coronary syndrome","volume":"105","author":"Adamson","year":"2019","journal-title":"Heart"},{"issue":"1","key":"10.1016\/j.jacc.2025.12.052_bib23","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1186\/s12916-023-02921-8","article-title":"Trajectories of cardiac troponin in the decades before cardiovascular death: a longitudinal cohort study","volume":"21","author":"Kimenai","year":"2023","journal-title":"BMC Med"},{"issue":"11","key":"10.1016\/j.jacc.2025.12.052_bib24","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.121.025082","article-title":"Temporal changes of stable high-sensitivity cardiac troponin T levels and prognosis","volume":"11","author":"Roos","year":"2022","journal-title":"J Am Heart Assoc"},{"issue":"7","key":"10.1016\/j.jacc.2025.12.052_bib25","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1373\/clinchem.2018.300061","article-title":"High-sensitivity cardiac troponin I assay for early diagnosis of acute myocardial infarction","volume":"65","author":"Boeddinghaus","year":"2019","journal-title":"Clin Chem"},{"issue":"11","key":"10.1016\/j.jacc.2025.12.052_bib26","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1373\/clinchem.2019.304725","article-title":"Clinical use of a new high-sensitivity cardiac troponin I assay in patients with suspected myocardial infarction","volume":"65","author":"Boeddinghaus","year":"2019","journal-title":"Clin Chem"},{"issue":"8","key":"10.1016\/j.jacc.2025.12.052_bib27","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1373\/clinchem.2018.294272","article-title":"Diagnostic accuracy of a high-sensitivity cardiac troponin assay with a single serum test in the emergency department","volume":"65","author":"Body","year":"2019","journal-title":"Clin Chem"},{"issue":"8","key":"10.1016\/j.jacc.2025.12.052_bib28","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1093\/clinchem\/hvaf068","article-title":"Influence of macrotroponin on the 99th percentile threshold in 2 high-sensitivity cardiac troponin assays","volume":"71","author":"Strandkj\u00e6r","year":"2025","journal-title":"Clin Chem"},{"issue":"24","key":"10.1016\/j.jacc.2025.12.052_bib29","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1161\/CIRCULATIONAHA.121.058489","article-title":"Skeletal muscle disorders: a noncardiac source of cardiac troponin T","volume":"145","author":"du Fay de Lavallaz","year":"2022","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.jacc.2025.12.052_bib30","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1373\/clinchem.2017.277210","article-title":"Prospective validation of a biomarker-based rule out strategy for functionally relevant coronary artery disease","volume":"64","author":"Walter","year":"2018","journal-title":"Clin Chem"},{"issue":"23","key":"10.1016\/j.jacc.2025.12.052_bib31","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1161\/CIRCULATIONAHA.114.014129","article-title":"Misdiagnosis of myocardial infarction related to limitations of the current regulatory approach to define clinical decision values for cardiac troponin","volume":"131","author":"Wildi","year":"2015","journal-title":"Circulation"},{"issue":"10","key":"10.1016\/j.jacc.2025.12.052_bib32","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.124.040468","article-title":"Possible misdiagnosis of myocardial infarction using regulatory-approved and close-to-bioequivalent upper limits of normal for cardiac troponin","volume":"14","author":"Wildi","year":"2025","journal-title":"J Am Heart Assoc"}],"container-title":["JACC"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109725105846?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109725105846?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T19:35:04Z","timestamp":1778960104000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109725105846"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":29,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S0735109725105846"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2025.12.052","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High-Sensitivity Cardiac Troponin T-gen6 Assay in Suspected Myocardial Infarction","name":"articletitle","label":"Article Title"},{"value":"JACC","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2025.12.052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}]}}