{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T19:02:23Z","timestamp":1762974143649,"version":"3.45.0"},"reference-count":7,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Case Reports"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.jaccas.2023.102171","type":"journal-article","created":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T05:30:30Z","timestamp":1702618230000},"page":"102171","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Competing Genetic Traits and Their\u00a0Influence on LDL Cholesterol Concentration in Familial Hypercholesterolemia"],"prefix":"10.1016","volume":"29","author":[{"given":"Christopher","family":"Song","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5599-0633","authenticated-orcid":false,"given":"Robert S.","family":"Rosenson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaccas.2023.102171_bib1","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1016\/j.jacc.2017.09.001","article-title":"How low to go with glucose, cholesterol, and blood pressure in primary prevention of CVD","volume":"70","author":"Hong","year":"2017","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jaccas.2023.102171_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.jlr.2021.100060","article-title":"Existing and emerging therapies for the treatment of familial hypercholesterolemia","volume":"62","author":"Rosenson","year":"2021","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.jaccas.2023.102171_bib3","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.jacc.2018.05.044","article-title":"Clinical genetic testing for familial hypercholesterolemia","volume":"72","author":"Sturm","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jaccas.2023.102171_bib4","doi-asserted-by":"crossref","first-page":"2578","DOI":"10.1016\/j.jacc.2016.03.520","article-title":"Diagnostic yield of sequencing familial hypercholesterolemia genes in severe hypercholesterolemia","volume":"67","author":"Khera","year":"2016","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jaccas.2023.102171_bib5","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1016\/S0140-6736(21)01372-6","article-title":"Familial hypercholesterolaemia: too many lost opportunities","volume":"398","author":"Cuchel","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.jaccas.2023.102171_bib6","doi-asserted-by":"crossref","first-page":"aaf7000","DOI":"10.1126\/science.aaf7000","article-title":"Genetic identification of familial hypercholesterolemia within a single U.S. health care system","volume":"354","author":"Abul-Husn","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.jaccas.2023.102171_bib7","doi-asserted-by":"crossref","first-page":"791","DOI":"10.5551\/jat.RV17052","article-title":"Diagnosis and management of sitosterolemia 2021","volume":"28","author":"Tada","year":"2021","journal-title":"J\u00a0Atheroscler Thromb"}],"container-title":["JACC: Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666084923005272?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666084923005272?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T18:50:58Z","timestamp":1762973458000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666084923005272"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["S2666084923005272"],"URL":"https:\/\/doi.org\/10.1016\/j.jaccas.2023.102171","relation":{},"ISSN":["2666-0849"],"issn-type":[{"type":"print","value":"2666-0849"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Competing Genetic Traits and Their\u00a0Influence on LDL Cholesterol Concentration in Familial Hypercholesterolemia","name":"articletitle","label":"Article Title"},{"value":"JACC: Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaccas.2023.102171","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}],"article-number":"102171"}}