{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T11:44:51Z","timestamp":1771328691044,"version":"3.50.1"},"reference-count":9,"publisher":"Elsevier BV","issue":"22","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T00:00:00Z","timestamp":1749427200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24K11288"],"award-info":[{"award-number":["24K11288"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Case Reports"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.jaccas.2025.104569","type":"journal-article","created":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T18:36:12Z","timestamp":1754505372000},"page":"104569","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Atrioventricular Block in a Pompe Disease Patient Receiving Enzyme Replacement Therapy"],"prefix":"10.1016","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2301-9236","authenticated-orcid":false,"given":"Kentaro","family":"Akagi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiro","family":"Baba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0992-064X","authenticated-orcid":false,"given":"Takeshi","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuya","family":"Hirata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Yokoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumiya","family":"Yoneda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumiaki","family":"Fukumura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eitaro","family":"Kume","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junko","family":"Takita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaccas.2025.104569_bib1","doi-asserted-by":"crossref","first-page":"3100","DOI":"10.1253\/circj.CJ-18-0449","article-title":"Enzyme replacement therapy provides effective, long-term treatment of cardiomyopathy in pompe disease","volume":"82","author":"Baba","year":"2018","journal-title":"Circ J"},{"key":"10.1016\/j.jaccas.2025.104569_bib2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.pedneo.2013.03.009","article-title":"Pompe disease: early diagnosis and early treatment make a difference","volume":"54","author":"chien","year":"2013","journal-title":"Pediatr Neonatal"},{"key":"10.1016\/j.jaccas.2025.104569_bib3","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1212\/01.wnl.0000251268.41188.04","article-title":"Recombinant human acid alpha-glucosidase: major clinical benefits in infantile-onset pompe disease","volume":"68","author":"Kishnani","year":"2007","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.jaccas.2025.104569_bib4","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/GIM.0b013e31819d0996","article-title":"Clinical outcomes after long-term treatment with alglucosidase alfa in infants and children with advanced pompe disease","volume":"11","author":"Nicolino","year":"2009","journal-title":"Genet Med"},{"issue":"5","key":"10.1016\/j.jaccas.2025.104569_bib5","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1097\/01.gim.0000195896.04069.5f","article-title":"Electrocardiogrphic response to enzyme replacement therapy for pompe disease","volume":"8","author":"Ansong","year":"2006","journal-title":"Genet Med"},{"key":"10.1016\/j.jaccas.2025.104569_bib6","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/BF02265613","article-title":"The conduction system in pompe's disease","volume":"2","author":"Bharati","year":"1982","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.jaccas.2025.104569_bib7","first-page":"622","article-title":"Electrophysiological mechanism of the short PR interval in pompe disease","volume":"128","author":"Gilette","year":"1974","journal-title":"Am J Dis Child"},{"issue":"9","key":"10.1016\/j.jaccas.2025.104569_bib8","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1038\/gim.2012.44","article-title":"The emerging phenotype of long-term survivors with infantile pompe disease","volume":"14","author":"Prater","year":"2012","journal-title":"Genet Med"},{"key":"10.1016\/j.jaccas.2025.104569_bib9","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.nmd.2014.04.005","article-title":"Atrio-ventricular block requiring pacemaker in patients with late onset pompe disease","volume":"24","author":"Sacconi","year":"2014","journal-title":"Neuromuscul Disord"}],"container-title":["JACC: Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S266608492501349X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S266608492501349X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T18:11:28Z","timestamp":1758132688000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S266608492501349X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":9,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S266608492501349X"],"URL":"https:\/\/doi.org\/10.1016\/j.jaccas.2025.104569","relation":{},"ISSN":["2666-0849"],"issn-type":[{"value":"2666-0849","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Atrioventricular Block in a Pompe Disease Patient Receiving Enzyme Replacement Therapy","name":"articletitle","label":"Article Title"},{"value":"JACC: Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaccas.2025.104569","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}],"article-number":"104569"}}