{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T03:17:10Z","timestamp":1770779830215,"version":"3.50.0"},"reference-count":19,"publisher":"Elsevier BV","issue":"13","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,12,26]],"date-time":"2018-12-26T00:00:00Z","timestamp":1545782400000},"content-version":"vor","delay-in-days":390,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003142","name":"Fonds NutsOhra","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003142","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Clinical Electrophysiology"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1016\/j.jacep.2017.07.006","type":"journal-article","created":{"date-parts":[[2017,9,13]],"date-time":"2017-09-13T14:45:24Z","timestamp":1505313924000},"page":"1592-1598","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["Temporal Relationship of Asystole to Onset of Transient Loss of Consciousness in Tilt-Induced Reflex Syncope"],"prefix":"10.1016","volume":"3","author":[{"given":"Dirk P.","family":"Saal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland D.","family":"Thijs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik W.","family":"van Zwet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianne","family":"Bootsma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Brignole","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David G.","family":"Benditt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Gert","family":"van Dijk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacep.2017.07.006_bib1","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1053\/euhj.2001.2739","article-title":"Guidelines on management (diagnosis and treatment) of syncope","volume":"22","author":"Brignole","year":"2001","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacep.2017.07.006_bib2","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.1093\/eurheartj\/ehp298","article-title":"Guidelines for the diagnosis and management of syncope (version 2009)","volume":"30","author":"Moya","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacep.2017.07.006_bib3","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1111\/j.1540-8159.1997.tb03622.x","article-title":"Pathophysiological mechanisms underlying vasovagal syncope in young subjects","volume":"20","author":"Wieling","year":"1997","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.jacep.2017.07.006_bib4","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.pcad.2012.10.016","article-title":"Pathophysiological basis of syncope and neurological conditions that mimic syncope","volume":"55","author":"van Dijk","year":"2013","journal-title":"Prog Cardiovasc Dis"},{"key":"10.1016\/j.jacep.2017.07.006_bib5","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1038\/nrneurol.2009.99","article-title":"A\u00a0guide to disorders causing transient loss of consciousness: focus on syncope","volume":"5","author":"van Dijk","year":"2009","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.jacep.2017.07.006_bib6","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/S0735-1097(83)80014-X","article-title":"The Bezold-Jarisch reflex revisited: clinical implications of inhibitory reflexes originating in the heart","volume":"1","author":"Mark","year":"1983","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacep.2017.07.006_bib7","doi-asserted-by":"crossref","first-page":"2630","DOI":"10.1093\/brain\/awp179","article-title":"Symptoms and signs of syncope: a review of the link between physiology and clinical clues","volume":"132","author":"Wieling","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.jacep.2017.07.006_bib8","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1001\/archneurpsyc.1943.02290230022002","article-title":"Acute arrest of cerebral circulation in man","volume":"50","author":"Rossen","year":"1943","journal-title":"Arch NeurPsych"},{"key":"10.1016\/j.jacep.2017.07.006_bib9","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1161\/CIRCEP.113.001103","article-title":"Benefit of pacemaker therapy in patients with presumed neurally mediated syncope and documented asystole is greater when tilt test is negative: an analysis from the third International Study on Syncope of Uncertain Etiology (ISSUE-3)","volume":"7","author":"Brignole","year":"2014","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.jacep.2017.07.006_bib10","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1093\/europace\/euv343","article-title":"Standardized algorithm for cardiac pacing in older patients affected by severe unpredictable reflex syncope: 3-year insights from Syncope Unit Project 2 (SUP 2) study","volume":"18","author":"Brignole","year":"2016","journal-title":"Europace"},{"key":"10.1016\/j.jacep.2017.07.006_bib11","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1212\/WNL.0000000000002184","article-title":"Tilt-induced vasovagal syncope and psychogenic pseudosyncope: overlapping clinical entities [published correction appears in Neurology 2017;88:335]","volume":"85","author":"Blad","year":"2015","journal-title":"Neurology"},{"key":"10.1016\/j.jacep.2017.07.006_bib12","doi-asserted-by":"crossref","first-page":"658","DOI":"10.5603\/CJ.a2014.0070","article-title":"Managing psychogenic pseudosyncope: facts and experiences","volume":"21","author":"Tannemaat","year":"2014","journal-title":"Cardiol J"},{"key":"10.1016\/j.jacep.2017.07.006_bib13","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1212\/WNL.0b013e3182a1aa88","article-title":"The semiology of\u00a0tilt-induced psychogenic pseudosyncope","volume":"81","author":"Tannemaat","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.jacep.2017.07.006_bib14","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/brain\/awt332","article-title":"The semiology of tilt-induced reflex syncope in relation to electroencephalographic changes","volume":"137","author":"van Dijk","year":"2014","journal-title":"Brain"},{"key":"10.1016\/j.jacep.2017.07.006_bib15","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/j.clinph.2015.07.037","article-title":"Tilt table testing in neurology and clinical neurophysiology","volume":"127","author":"Saal","year":"2016","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.jacep.2017.07.006_bib16","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1053\/eupc.2000.0125","article-title":"\u201cThe Italian Protocol\u201d: a simplified head-up tilt testing potentiated with oral nitroglycerin to assess patients with unexplained syncope","volume":"2","author":"Bartoletti","year":"2000","journal-title":"Europace"},{"key":"10.1016\/j.jacep.2017.07.006_bib17","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1093\/europace\/eul135","article-title":"International study on syncope of uncertain aetiology 3 (ISSUE 3): pacemaker therapy for patients with asystolic neurally-mediated syncope: rationale and study design","volume":"9","author":"Brignole","year":"2007","journal-title":"Europace"},{"key":"10.1016\/j.jacep.2017.07.006_bib18","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1001\/jama.289.17.2224","article-title":"Pacemaker therapy for prevention of syncope in patients with recurrent severe vasovagal syncope: Second Vasovagal Pacemaker Study (VPS II): a randomized trial","volume":"289","author":"Connolly","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.jacep.2017.07.006_bib19","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1093\/eurheartj\/ehu255","article-title":"Twenty-eight years of research permit reinterpretation of tilt-testing: hypotensive susceptibility rather than diagnosis","volume":"35","author":"Sutton","year":"2014","journal-title":"Eur Heart J"}],"container-title":["JACC: Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405500X17305443?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405500X17305443?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T07:24:33Z","timestamp":1762500273000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405500X17305443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":19,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["S2405500X17305443"],"URL":"https:\/\/doi.org\/10.1016\/j.jacep.2017.07.006","relation":{},"ISSN":["2405-500X"],"issn-type":[{"value":"2405-500X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Temporal Relationship of Asystole to Onset of Transient Loss of Consciousness in Tilt-Induced Reflex Syncope","name":"articletitle","label":"Article Title"},{"value":"JACC: Clinical Electrophysiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacep.2017.07.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}