{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:27:41Z","timestamp":1786991261559,"version":"build-2736575974"},"reference-count":29,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Clinical Electrophysiology"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.jacep.2021.06.011","type":"journal-article","created":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T14:00:09Z","timestamp":1629900009000},"page":"59-69","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Efficacy of His Bundle Pacing on LV\u00a0Relaxation and Clinical Improvement in HF\u00a0and\u00a0LBBB"],"prefix":"10.1016","volume":"8","author":[{"given":"Hiroyuki","family":"Kato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Yanagisawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taku","family":"Sakurai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiaki","family":"Mizuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryusuke","family":"Ota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazumasa","family":"Suga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisashi","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Kada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuya","family":"Inden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoya","family":"Tsuboi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toyoaki","family":"Murohara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacep.2021.06.011_bib1","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1056\/NEJMoa013168","article-title":"Cardiac resynchronization in chronic heart failure","volume":"346","author":"Abraham","year":"2002","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacep.2021.06.011_bib2","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1056\/NEJMoa050496","article-title":"The effect of cardiac resynchronization on morbidity and mortality in heart failure","volume":"352","author":"Cleland","year":"2005","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacep.2021.06.011_bib3","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1056\/NEJMoa0906431","article-title":"Cardiac-resynchronization therapy for the prevention of heart-failure events","volume":"361","author":"Moss","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacep.2021.06.011_bib4","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1056\/NEJMoa1009540","article-title":"Cardiac-resynchronization therapy for mild-to-moderate heart failure","volume":"363","author":"Tang","year":"2010","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacep.2021.06.011_bib5","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1161\/CIRCULATIONAHA.105.538272","article-title":"Left ventricular reverse remodeling but not clinical improvement predicts long-term survival after cardiac resynchronization therapy","volume":"112","author":"Yu","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.jacep.2021.06.011_bib6","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1016\/j.hrthm.2015.03.048","article-title":"His bundle pacing versus biventricular pacing in cardiac resynchronization therapy patients: a crossover design comparison","volume":"12","author":"Lustgarten","year":"2015","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jacep.2021.06.011_bib7","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.hrthm.2017.10.014","article-title":"Permanent His bundle pacing as an alternative to biventricular pacing for cardiac resynchronization therapy: a multicenter experience","volume":"15","author":"Sharma","year":"2018","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jacep.2021.06.011_bib8","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1016\/j.hrthm.2019.05.009","article-title":"On-treatment comparison between corrective His bundle pacing and biventricular pacing for cardiac resynchronization: a secondary analysis of the His-SYNC Pilot Trial","volume":"16","author":"Upadhyay","year":"2019","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jacep.2021.06.011_bib9","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1136\/heartjnl-2018-313415","article-title":"Long-term outcomes of His bundle pacing in patients with heart failure with left bundle branch block","volume":"105","author":"Huang","year":"2019","journal-title":"Heart"},{"key":"10.1016\/j.jacep.2021.06.011_bib10","first-page":"319","article-title":"Left bundle branch pacing for cardiac resynchronization therapy: nonrandomized on-treatment comparison with His bundle pacing and biventricular pacing","volume":"37","author":"Wu","year":"2021","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.jacep.2021.06.011_bib11","doi-asserted-by":"crossref","first-page":"3112","DOI":"10.1016\/j.jacc.2018.09.073","article-title":"His resynchronization versus biventricular pacing in patients with heart failure and left bundle branch block","volume":"72","author":"Arnold","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacep.2021.06.011_bib12","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1253\/circj.CJ-20-0637","article-title":"JCS\/JHRS 2019 Guideline on Non-Pharmacotherapy of Cardiac Arrhythmias","volume":"85","author":"Nogami","year":"2021","journal-title":"Circ J"},{"key":"10.1016\/j.jacep.2021.06.011_bib13","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.jacc.2008.12.013","volume":"53","author":"Surawicz","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacep.2021.06.011_bib14","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1093\/europace\/eum119","article-title":"Acute and chronic effects of cardiac resynchronization in patients developing heart failure with long-term pacemaker therapy for acquired complete atrioventricular block","volume":"9","author":"Shimano","year":"2007","journal-title":"Europace"},{"key":"10.1016\/j.jacep.2021.06.011_bib15","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1111\/j.1540-8159.2006.00500.x","article-title":"Does RV lead positioning provide additional benefit to cardiac resynchronization therapy in patients with advanced heart failure?","volume":"29","author":"Shimano","year":"2006","journal-title":"Pacing Clin Electrophysiol"},{"issue":"Suppl 1","key":"10.1016\/j.jacep.2021.06.011_bib16","first-page":"S40","article-title":"Effects of stimulation site on diastolic function in cardiac resynchronization therapy","volume":"30","author":"de Cock","year":"2007","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.jacep.2021.06.011_bib17","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.jacc.2009.08.045","article-title":"Optimizing hemodynamics in heart failure patients by systematic screening of left ventricular pacing sites: the lateral left ventricular wall and the coronary sinus are rarely the best sites","volume":"55","author":"Derval","year":"2010","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacep.2021.06.011_bib18","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.hrthm.2014.10.021","article-title":"Permanent His bundle pacing is feasible, safe, and superior to right ventricular pacing in routine clinical practice","volume":"12","author":"Sharma","year":"2015","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jacep.2021.06.011_bib19","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.jacc.2019.04.026","article-title":"His corrective pacing or biventricular pacing for cardiac resynchronization in heart failure","volume":"74","author":"Upadhyay","year":"2019","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacep.2021.06.011_bib20","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.hrthm.2017.04.003","article-title":"Permanent His bundle pacing for cardiac resynchronization therapy: initial feasibility study in lieu of left ventricular lead","volume":"14","author":"Ajijola","year":"2017","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jacep.2021.06.011_bib21","first-page":"125","article-title":"Early improvement of left ventricular ejection fraction by cardiac resynchronization through His bundle pacing in patients with heart failure","volume":"22","author":"Mori\u00f1a-V\u00e1zquez","year":"2020","journal-title":"Europace"},{"key":"10.1016\/j.jacep.2021.06.011_bib22","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1016\/j.jacc.2005.05.094","article-title":"Improvements in left ventricular diastolic function after cardiac resynchronization therapy are coupled to response in systolic performance","volume":"46","author":"Waggoner","year":"2005","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacep.2021.06.011_bib23","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.1016\/j.jacc.2005.02.096","article-title":"Diastolic asynchrony is more frequent than systolic asynchrony in dilated cardiomyopathy and is less improved by cardiac resynchronization therapy","volume":"46","author":"Schuster","year":"2005","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacep.2021.06.011_bib24","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.hrthm.2013.11.023","article-title":"Multipoint left ventricular pacing improves acute hemodynamic response assessed with pressure-volume loops in cardiac resynchronization therapy patients","volume":"11","author":"Pappone","year":"2014","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jacep.2021.06.011_bib25","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1161\/CIRCEP.111.970277","article-title":"Acute hemodynamic effect of left ventricular endocardial pacing in cardiac resynchronization therapy: assessment by pressure-volume loops","volume":"5","author":"Padeletti","year":"2012","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.jacep.2021.06.011_bib26","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1111\/pace.12478","article-title":"Acute improvement of left ventricular relaxation as a predictor of volume reduction after cardiac resynchronization therapy: a pilot study assessing the value of left ventricular hemodynamic parameter","volume":"37","author":"Kato","year":"2014","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.jacep.2021.06.011_bib27","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1161\/CIRCULATIONAHA.118.038648","article-title":"Intracardiac delineation of septal conduction in left bundle-branch block patterns","volume":"139","author":"Upadhyay","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.jacep.2021.06.011_bib28","first-page":"1736.e1","article-title":"A\u00a0novel pacing strategy with low and stable output: pacing the left bundle branch immediately beyond the conduction block","volume":"33","author":"Huang","year":"2017","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.jacep.2021.06.011_bib29","first-page":"135","article-title":"Left bundle branch area pacing for cardiac\u00a0resynchronization therapy: results from the international LBBAP collaborative study\u00a0group","volume":"7","author":"Vijayaraman","year":"2021","journal-title":"J\u00a0Am Coll Cardiol EP"}],"container-title":["JACC: Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405500X21005946?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405500X21005946?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T07:30:24Z","timestamp":1762500624000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405500X21005946"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["S2405500X21005946"],"URL":"https:\/\/doi.org\/10.1016\/j.jacep.2021.06.011","relation":{},"ISSN":["2405-500X"],"issn-type":[{"value":"2405-500X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of His Bundle Pacing on LV\u00a0Relaxation and Clinical Improvement in HF\u00a0and\u00a0LBBB","name":"articletitle","label":"Article Title"},{"value":"JACC: Clinical Electrophysiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacep.2021.06.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}