{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:39:34Z","timestamp":1791319174824,"version":"4.3.1"},"reference-count":21,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Clinical Electrophysiology"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.jacep.2021.07.010","type":"journal-article","created":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T11:04:31Z","timestamp":1627556671000},"page":"1493-1501","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Safety\/Efficacy of DOAC Versus Aspirin for Reduction of Risk of Cerebrovascular Events Following VT Ablation"],"prefix":"10.1016","volume":"7","author":[{"given":"Dhanunjaya","family":"Lakkireddy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayaprakash","family":"Shenthar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jalaj","family":"Garg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Padmanabhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakesh","family":"Gopinathannair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Di Biase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Romero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanghamitra","family":"Mohanty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Burkhardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amin","family":"Al-Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donita","family":"Atkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudha","family":"Bommana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Natale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacep.2021.07.010_bib1","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1016\/j.hrthm.2014.07.012","article-title":"Catheter ablation of postinfarction ventricular tachycardia: ten-year trends in utilization, in-hospital complications, and in-hospital mortality in the United States","volume":"11","author":"Palaniswamy","year":"2014","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jacep.2021.07.010_bib2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0140-6736(09)61755-4","article-title":"Catheter ablation of stable ventricular tachycardia before defibrillator implantation in patients with coronary heart disease (VTACH): a multicentre randomised controlled trial","volume":"375","author":"Kuck","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.jacep.2021.07.010_bib3","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1016\/j.hrthm.2011.05.017","article-title":"Incidence and predictors of major complications from contemporary catheter ablation to treat cardiac arrhythmias","volume":"8","author":"Bohnen","year":"2011","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jacep.2021.07.010_bib4","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1161\/CIRCULATIONAHA.116.025546","article-title":"Brain emboli after left ventricular endocardial ablation","volume":"135","author":"Whitman","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.jacep.2021.07.010_bib5","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1056\/NEJMoa065457","article-title":"Prophylactic catheter ablation for the prevention of defibrillator therapy","volume":"357","author":"Reddy","year":"2007","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacep.2021.07.010_bib6","doi-asserted-by":"crossref","first-page":"2773","DOI":"10.1161\/CIRCULATIONAHA.108.788604","article-title":"Irrigated radiofrequency catheter ablation guided by electroanatomic mapping for recurrent ventricular tachycardia after myocardial infarction: the Multicenter Thermocool Ventricular Tachycardia Ablation trial","volume":"118","author":"Stevenson","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.jacep.2021.07.010_bib7","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1016\/j.hrthm.2011.06.030","article-title":"Postablation asymptomatic cerebral lesions: long-term follow-up using magnetic resonance imaging","volume":"8","author":"Deneke","year":"2011","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jacep.2021.07.010_bib8","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1161\/CIRCULATIONAHA.110.937953","article-title":"Radiofrequency catheter ablation of atrial fibrillation: a cause of silent thromboembolism? Magnetic resonance imaging assessment of cerebral thromboembolism in patients undergoing ablation of atrial fibrillation","volume":"122","author":"Gaita","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jacep.2021.07.010_bib9","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.jacc.2011.04.010","article-title":"Incidence of asymptomatic intracranial embolic events after pulmonary vein isolation: comparison of different atrial fibrillation ablation technologies in a multicenter study","volume":"58","author":"Herrera Siklody","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacep.2021.07.010_bib10","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1111\/j.1540-8167.2009.01540.x","article-title":"Incidence and predictors of periprocedural cerebrovascular accident in patients undergoing catheter ablation of atrial fibrillation","volume":"20","author":"Scherr","year":"2009","journal-title":"J\u00a0Cardiovasc Electrophysiol"},{"issue":"13","key":"10.1016\/j.jacep.2021.07.010_bib11","article-title":"Cerebral protection during catheter ablation of ventricular tachycardia in patients with ischemic heart disease","volume":"7","author":"Heeger","year":"2018","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.jacep.2021.07.010_bib12","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/j.1540-8167.2012.02420.x","article-title":"3 Tesla MRI-detected brain lesions after pulmonary vein isolation for atrial fibrillation: results of the MACPAF study","volume":"24","author":"Haeusler","year":"2013","journal-title":"J\u00a0Cardiovasc Electrophysiol"},{"key":"10.1016\/j.jacep.2021.07.010_bib13","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1093\/oxfordjournals.eurheartj.a059578","article-title":"Thrombus apposition on catheter ablation injuries","volume":"10","author":"Moro","year":"1989","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacep.2021.07.010_bib14","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/clc.4960270210","article-title":"Comparison of hemostatic activation created by right- and left-heart radiofrequency catheter ablation","volume":"27","author":"Charng","year":"2004","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.jacep.2021.07.010_bib15","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1111\/jce.14051","article-title":"Silent and non-silent thromboembolic events after ventricular tachycardia ablation: modifiable risk with postprocedure anticoagulation?","volume":"30","author":"Siontis","year":"2019","journal-title":"J\u00a0Cardiovasc Electrophysiol"},{"key":"10.1016\/j.jacep.2021.07.010_bib16","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/S0140-6736(03)12978-9","article-title":"Silent and apparent cerebral embolism after retrograde catheterisation of the aortic valve in valvular stenosis: a prospective, randomised study","volume":"361","author":"Omran","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.jacep.2021.07.010_bib17","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.ijcard.2009.10.053","article-title":"Incidence and predictors of silent embolic cerebral infarction following diagnostic coronary angiography","volume":"148","author":"Kim","year":"2011","journal-title":"Int J Cardiol"},{"issue":"3","key":"10.1016\/j.jacep.2021.07.010_bib18","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.116.004422","volume":"10","author":"Kuck","year":"2017","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.jacep.2021.07.010_bib19","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1001\/jama.2019.0693","article-title":"Effect of catheter ablation vs antiarrhythmic drug therapy on mortality, stroke, bleeding, and cardiac arrest among patients with atrial fibrillation: the CABANA randomized clinical trial","volume":"321","author":"Packer","year":"2019","journal-title":"JAMA"},{"key":"10.1016\/j.jacep.2021.07.010_bib20","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1056\/NEJMoa1707855","article-title":"Catheter ablation for atrial fibrillation with\u00a0heart failure","volume":"378","author":"Marrouche","year":"2018","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacep.2021.07.010_bib21","doi-asserted-by":"crossref","first-page":"e275","DOI":"10.1016\/j.hrthm.2017.05.012","article-title":"2017 HRS\/EHRA\/ECAS\/APHRS\/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation","volume":"14","author":"Calkins","year":"2017","journal-title":"Heart Rhythm"}],"container-title":["JACC: Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405500X21006848?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405500X21006848?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T07:32:20Z","timestamp":1762500740000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405500X21006848"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":21,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["S2405500X21006848"],"URL":"https:\/\/doi.org\/10.1016\/j.jacep.2021.07.010","relation":{},"ISSN":["2405-500X"],"issn-type":[{"value":"2405-500X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Safety\/Efficacy of DOAC Versus Aspirin for Reduction of Risk of Cerebrovascular Events Following VT Ablation","name":"articletitle","label":"Article Title"},{"value":"JACC: Clinical Electrophysiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacep.2021.07.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}