{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T19:41:44Z","timestamp":1780602104495,"version":"3.54.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Clinical Electrophysiology"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.jacep.2022.11.020","type":"journal-article","created":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T17:59:05Z","timestamp":1674064745000},"page":"979-988","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"P1","title":["Age and the Risk of Ventricular Tachyarrhythmia in Patients With an Implantable Cardioverter-Defibrillator"],"prefix":"10.1016","volume":"9","author":[{"given":"Mehmet K.","family":"Akta\u015f","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arwa","family":"Younis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5155-5992","authenticated-orcid":false,"given":"Shireen","family":"Saxena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3989-9813","authenticated-orcid":false,"given":"Alexander","family":"Diamond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amole","family":"Ojo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Kutyifa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hillel","family":"Steiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan S.","family":"Steinberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Zareba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"McNitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bronislava","family":"Polonsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Spencer Z.","family":"Rosero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David T.","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilan","family":"Goldenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacep.2022.11.020_bib1","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1056\/NEJMoa013474","article-title":"Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction","volume":"346","author":"Moss","year":"2002","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacep.2022.11.020_bib2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1056\/NEJMoa043399","article-title":"Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure","volume":"352","author":"Bardy","year":"2005","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacep.2022.11.020_bib3","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1056\/NEJMoa0906431","article-title":"Cardiac-resynchronization therapy for the prevention of heart-failure events","volume":"361","author":"Moss","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacep.2022.11.020_bib4","doi-asserted-by":"crossref","first-page":"e59","DOI":"10.1016\/j.hrthm.2013.01.035","article-title":"The National ICD registry report: version 2.1 including leads and pediatrics for years 2010 and 2011","volume":"10","author":"Kremers","year":"2013","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jacep.2022.11.020_bib5","doi-asserted-by":"crossref","first-page":"592","DOI":"10.7326\/0003-4819-153-9-201011020-00009","article-title":"Meta-analysis: age and effectiveness of prophylactic implantable cardioverter-defibrillators","volume":"153","author":"Santangeli","year":"2010","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jacep.2022.11.020_bib6","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1016\/j.amjcard.2014.09.026","article-title":"Comparison of age (<75 years versus\u00a0\u226575 years) to risk of ventricular tachyarrhythmias and implantable cardioverter defibrillator shocks (from the Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy)","volume":"114","author":"Aktas","year":"2014","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacep.2022.11.020_bib7","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1186\/s12916-018-1148-x","article-title":"Frailty trajectories to identify end of life: a longitudinal population-based study","volume":"16","author":"Stow","year":"2018","journal-title":"BMC Med"},{"key":"10.1016\/j.jacep.2022.11.020_bib8","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1053\/j.ackd.2014.06.007","article-title":"The interplay between CKD, sudden cardiac death, and ventricular arrhythmias","volume":"21","author":"Pun","year":"2014","journal-title":"Adv Chronic Kidney Dis"},{"key":"10.1016\/j.jacep.2022.11.020_bib9","author":"Zareba"},{"key":"10.1016\/j.jacep.2022.11.020_bib10","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1056\/NEJMoa1211107","article-title":"Reduction in inappropriate therapy and mortality through ICD programming","volume":"367","author":"Moss","year":"2012","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacep.2022.11.020_bib11","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.jacc.2018.04.086","article-title":"Ranolazine in high-risk patients with implanted cardioverter-defibrillators: the RAID trial","volume":"72","author":"Zareba","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacep.2022.11.020_bib12","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2307\/3001666","article-title":"The combination of estimates from different experiments","volume":"10","author":"Cochran","year":"1954","journal-title":"Biometrics"},{"key":"10.1016\/j.jacep.2022.11.020_bib13","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1214\/aos\/1176350951","article-title":"A\u00a0Class of K-sample tests for comparing the cumulative incidence of a competing risk","volume":"16","author":"Gray","year":"1988","journal-title":"Ann Stat"},{"key":"10.1016\/j.jacep.2022.11.020_bib14","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1080\/01621459.1999.10474144","article-title":"A\u00a0proportional hazards model for the subdistribution of a competing risk","volume":"94","author":"Fine","year":"1999","journal-title":"J\u00a0Am Stat Assoc"},{"key":"10.1016\/j.jacep.2022.11.020_bib15","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.jacep.2022.11.020_bib16","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.ahj.2003.12.017","article-title":"Diminishing proportional risk of sudden death with advancing age: implications for prevention of sudden death","volume":"147","author":"Krahn","year":"2004","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacep.2022.11.020_bib17","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1111\/pace.13215","article-title":"Implantable cardioverter-defibrillator in the elderly: Predictors of appropriate interventions and mortality at 12-month follow-up","volume":"40","author":"Ferretto","year":"2017","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.jacep.2022.11.020_bib18","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.ahj.2006.06.008","article-title":"Survival in octogenarians receiving implantable defibrillators","volume":"152","author":"Koplan","year":"2006","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacep.2022.11.020_bib19","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1161\/CIRCULATIONAHA.111.023838","article-title":"Epidemiology and genetics of sudden cardiac death","volume":"125","author":"Deo","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.jacep.2022.11.020_bib20","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1093\/europace\/euu296","article-title":"Implantable cardioverter-defibrillators in the elderly: rationale and specific age-related considerations","volume":"17","author":"Barra","year":"2014","journal-title":"Europace"},{"key":"10.1016\/j.jacep.2022.11.020_bib21","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1093\/eurheartj\/ehl438","article-title":"Role of the implantable defibrillator among elderly patients with a history of life-threatening ventricular arrhythmias","volume":"28","author":"Healey","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacep.2022.11.020_bib22","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1093\/europace\/eum015","article-title":"Comparison of ventricular arrhythmia burden, therapeutic interventions, and survival, in patients\u00a0< 75 and patients >or= 75 years of age treated with implantable cardioverter defibrillators","volume":"9","author":"Ermis","year":"2007","journal-title":"Europace"},{"key":"10.1016\/j.jacep.2022.11.020_bib23","doi-asserted-by":"crossref","first-page":"503","DOI":"10.5603\/CJ.2011.0005","article-title":"Use of implantable cardioverter-defibrillators for primary prevention in older patients: a systematic literature review and meta-analysis","volume":"18","author":"Kong","year":"2011","journal-title":"Cardiol J"},{"key":"10.1016\/j.jacep.2022.11.020_bib24","doi-asserted-by":"crossref","first-page":"111","DOI":"10.7326\/M13-1787","article-title":"Effectiveness of implantable cardioverter defibrillators for primary prevention of sudden cardiac death in subgroups a systematic review","volume":"160","author":"Earley","year":"2014","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jacep.2022.11.020_bib25","article-title":"For causal analysis of competing risks, don\u2019t use Fine & Gray\u2019s subdistribution method","author":"Allison","year":"2018","journal-title":"Statistical Horizons"}],"container-title":["JACC: Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405500X22010520?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405500X22010520?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T07:32:26Z","timestamp":1762500746000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405500X22010520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["S2405500X22010520"],"URL":"https:\/\/doi.org\/10.1016\/j.jacep.2022.11.020","relation":{},"ISSN":["2405-500X"],"issn-type":[{"value":"2405-500X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Age and the Risk of Ventricular Tachyarrhythmia in Patients With an Implantable Cardioverter-Defibrillator","name":"articletitle","label":"Article Title"},{"value":"JACC: Clinical Electrophysiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacep.2022.11.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}