{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T20:08:05Z","timestamp":1789243685777,"version":"build-2803163510"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000871","name":"Mayo Clinic Arizona","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Clinical Electrophysiology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.jacep.2026.07.018","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T20:47:44Z","timestamp":1789159664000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence and Prognostic Significance of Exercise-Accentuated J-Point Elevation in Brugada Syndrome"],"prefix":"10.1016","author":[{"given":"Mayank","family":"Sardana","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher N.","family":"Kanaan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal","family":"Youssef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Martijn","family":"Bos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas G.","family":"Allison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Ackerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Giudicessi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacep.2026.07.018_bib1","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1016\/0735-1097(92)90253-J","article-title":"Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report","volume":"20","author":"Brugada","year":"1992","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacep.2026.07.018_bib2","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.jacep.2021.12.001","article-title":"Brugada syndrome","volume":"8","author":"Krahn","year":"2022","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.jacep.2026.07.018_bib3","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.123.012072","article-title":"Clinical management of Brugada syndrome: commentary from the experts","volume":"17","author":"Cutler","year":"2024","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.jacep.2026.07.018_bib4","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1016\/j.jacc.2010.06.033","article-title":"Augmented ST-segment elevation during recovery from exercise predicts cardiac events in patients with Brugada syndrome","volume":"56","author":"Makimoto","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacep.2026.07.018_bib5","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1161\/CIRCEP.109.862441","article-title":"Exercise-induced ECG changes in Brugada syndrome","volume":"2","author":"Amin","year":"2009","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.jacep.2026.07.018_bib6","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1111\/jce.13205","article-title":"The utility of exercise testing in risk stratification of asymptomatic patients with type 1 brugada pattern","volume":"28","author":"Subramanian","year":"2017","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.jacep.2026.07.018_bib7","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/jce.13349","article-title":"Identification of electrocardiographic risk markers for the initial and recurrent episodes of ventricular fibrillation in patients with Brugada syndrome","volume":"29","author":"Morita","year":"2018","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.jacep.2026.07.018_bib8","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1136\/hrt.2009.174052","article-title":"Unmasking of the Brugada phenotype during exercise testing and its association with ventricular arrhythmia on the recovery phase","volume":"95","author":"Papadakis","year":"2009","journal-title":"Heart"},{"key":"10.1016\/j.jacep.2026.07.018_bib9","article-title":"Case series of type 1 Brugada pattern provoked by exercise: a role for diagnostic treadmill stress testing","volume":"10","author":"Mehta","year":"2026","journal-title":"Eur Heart J Case Rep"},{"key":"10.1016\/j.jacep.2026.07.018_bib10","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.hrcr.2022.01.009","article-title":"Exercise-induced Brugada syndrome type 1 pattern","volume":"8","author":"Aboyme","year":"2022","journal-title":"Heartrhythm Case Rep"},{"key":"10.1016\/j.jacep.2026.07.018_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0229078","article-title":"Dynamic changes in ventricular depolarization during exercise in patients with Brugada syndrome","volume":"15","author":"Romero","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.jacep.2026.07.018_bib12","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0197367","article-title":"Multivariate classification of Brugada syndrome patients based on autonomic response to exercise testing","volume":"13","author":"Calvo","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.jacep.2026.07.018_bib13","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.120.016907","article-title":"Significance of exercise-related ventricular arrhythmias in patients with Brugada syndrome","volume":"9","author":"Morita","year":"2020","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.jacep.2026.07.018_bib14","doi-asserted-by":"crossref","first-page":"e151","DOI":"10.1016\/j.hrthm.2024.05.018","article-title":"2024 HRS expert consensus statement on arrhythmias in the athlete: evaluation, treatment, and return to play","volume":"21","author":"Lampert","year":"2024","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jacep.2026.07.018_bib15","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1161\/CIRCULATIONAHA.125.076011","article-title":"Safety, utility, and outcomes of procainamide challenge for the diagnosis and exclusion of Brugada syndrome","volume":"153","author":"Moore","year":"2026","journal-title":"Circulation"},{"key":"10.1016\/j.jacep.2026.07.018_bib16","article-title":"Structure of human Na(v)1.5 reveals the fast inactivation-related segments as a mutational hotspot for the long QT syndrome","volume":"118","author":"Li","year":"2021","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jacep.2026.07.018_bib17","doi-asserted-by":"crossref","DOI":"10.1093\/europace\/euad157","article-title":"Evaluation of a new treadmill exercise protocol to unmask type 1 Brugada electrocardiographic pattern: can we improve diagnostic yield?","volume":"25","author":"Pichara","year":"2023","journal-title":"Europace"},{"key":"10.1016\/j.jacep.2026.07.018_bib18","doi-asserted-by":"crossref","first-page":"4201","DOI":"10.1113\/JP270139","article-title":"Differential thermosensitivity in mixed syndrome cardiac sodium channel mutants","volume":"593","author":"Abdelsayed","year":"2015","journal-title":"J Physiol"},{"key":"10.1016\/j.jacep.2026.07.018_bib19","doi-asserted-by":"crossref","first-page":"972","DOI":"10.3390\/s26030972","article-title":"A comprehensive review of non-invasive core body temperature measurement techniques","volume":"26","author":"Hashimoto","year":"2026","journal-title":"Sensors (Basel)"}],"container-title":["JACC: Clinical Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405500X26007449?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405500X26007449?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T20:04:32Z","timestamp":1789243472000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405500X26007449"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":19,"alternative-id":["S2405500X26007449"],"URL":"https:\/\/doi.org\/10.1016\/j.jacep.2026.07.018","relation":{},"ISSN":["2405-500X"],"issn-type":[{"value":"2405-500X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prevalence and Prognostic Significance of Exercise-Accentuated J-Point Elevation in Brugada Syndrome","name":"articletitle","label":"Article Title"},{"value":"JACC: Clinical Electrophysiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacep.2026.07.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}]}}