{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T16:34:35Z","timestamp":1793291675344,"version":"4.5.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2004,8]]},"DOI":"10.1016\/j.jaci.2004.04.029","type":"journal-article","created":{"date-parts":[[2004,8,17]],"date-time":"2004-08-17T09:09:01Z","timestamp":1092733741000},"page":"371-376","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":842,"title":["Clinical features and severity grading of anaphylaxis"],"prefix":"10.1016","volume":"114","author":[{"given":"Simon G.A","family":"Brown","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2004.04.029_BIB1","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1067\/mai.2001.119028","article-title":"Emergency department anaphylaxis: a review of 142 patients in a single year","volume":"108","author":"Brown","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.04.029_BIB2","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1046\/j.1442-2026.2003.00468.x","article-title":"The emergency department epidemiology of acute allergic events: can we ever compare apples with apples?","volume":"15","author":"Brown","year":"2003","journal-title":"Emerg Med"},{"key":"10.1016\/j.jaci.2004.04.029_BIB3","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0091-6749(05)80012-0","article-title":"Natural history of insect sting allergy: relationship of severity of symptoms of initial sting anaphylaxis to re-sting reactions","volume":"90","author":"Reisman","year":"1992","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.04.029_BIB4","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/S0091-6749(98)70239-8","article-title":"Discontinuing venom immunotherapy: extended observations","volume":"101","author":"Golden","year":"1998","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.04.029_BIB5","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1056\/NEJM195908202610803","article-title":"Further experiences with severe allergic reactions to insect stings","volume":"261","author":"Mueller","year":"1959","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2004.04.029_BIB6","doi-asserted-by":"crossref","first-page":"331","DOI":"10.3109\/02770906609106941","article-title":"Diagnosis and treatment of insect sensitivity","volume":"3","author":"Mueller","year":"1966","journal-title":"J Asthma Res"},{"key":"10.1016\/j.jaci.2004.04.029_BIB7","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/S0091-6749(05)80182-4","article-title":"The Hymenoptera venom study","volume":"86","author":"Lockey","year":"1990","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.04.029_BIB8","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1053\/ai.1994.v94.a54889","article-title":"Insect-sting challenge in 324 subjects with a previous anaphylactic reaction: current criteria for insect-venom hypersensitivity do not predict the occurrence and the severity of anaphylaxis","volume":"94","author":"van der Linden","year":"1994","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.04.029_BIB9","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0091-6749(96)70224-5","article-title":"The value of an in-hospital insect sting challenge as a criterion for application or omission of venom immunotherapy","volume":"98","author":"Blaauw","year":"1996","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.04.029_BIB10","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/S0140-6736(77)91953-5","article-title":"Incidence and severity of anaphylactoid reactions to colloid volume substitutes","volume":"1","author":"Ring","year":"1977","journal-title":"Lancet"},{"key":"10.1016\/j.jaci.2004.04.029_BIB11","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1067\/mai.2002.129124","article-title":"Rush Hymenoptera venom immunotherapy: a safe and practical protocol for high-risk patients","volume":"110","author":"Sturm","year":"2002","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.04.029_BIB12","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1046\/j.1365-2222.2000.00864.x","article-title":"Lessons for management of anaphylaxis from a study of fatal reactions","volume":"30","author":"Pumphrey","year":"2000","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2004.04.029_BIB13","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1067\/mai.2003.48","article-title":"Prevalence, severity, and natural history of jack jumper ant venom allergy in Tasmania","volume":"111","author":"Brown","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.04.029_BIB14","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1136\/emj.2003.009449","article-title":"Insect sting anaphylaxis; prospective evaluation of treatment with intravenous adrenaline and volume resuscitation","volume":"21","author":"Brown","year":"2004","journal-title":"Emerg Med J"},{"key":"10.1016\/j.jaci.2004.04.029_BIB15","series-title":"Insect sting allergy: clinical picture, diagnosis and treatment","author":"Muller","year":"1990"},{"key":"10.1016\/j.jaci.2004.04.029_BIB16","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1016\/S0091-6749(96)70258-0","article-title":"Hymenoptera sting challenge of 348 patients: relation to subsequent field stings","volume":"97","author":"van Halteren","year":"1996","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.04.029_BIB17","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.jaci.2003.10.053","article-title":"Multicenter study of emergency department visits for food allergies","volume":"113","author":"Clark","year":"2004","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.04.029_BIB18","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1056\/NEJM199208063270603","article-title":"Fatal and near-fatal anaphylactic reactions to food in children and adolescents","volume":"327","author":"Sampson","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2004.04.029_BIB19","doi-asserted-by":"crossref","first-page":"644","DOI":"10.5694\/j.1326-5377.2001.tb143761.x","article-title":"Fatal anaphylaxis following jack jumper ant sting in southern Tasmania","volume":"175","author":"Brown","year":"2001","journal-title":"Med J Aust"},{"key":"10.1016\/j.jaci.2004.04.029_BIB20","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/0140-6736(92)93314-D","article-title":"ACE inhibitors and anaphylactoid reactions during venom immunotherapy","volume":"340","author":"Tunon-de-Lara","year":"1992","journal-title":"Lancet"},{"key":"10.1016\/j.jaci.2004.04.029_BIB21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0091-6749(88)90212-6","article-title":"Risk of anaphylaxis in patients receiving beta-blocker drugs","volume":"81","author":"Toogood","year":"1988","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.04.029_BIB22","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0091-6749(81)90170-6","article-title":"Potentiated anaphylaxis in patients with drug-induced beta-adrenergic blockade","volume":"68","author":"Jacobs","year":"1981","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.04.029_BIB23","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1056\/NEJM198306233082513","article-title":"Severe anaphylaxis and drug-induced beta-blockade","volume":"308","author":"Hannaway","year":"1983","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2004.04.029_BIB24","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1398-9995.1983.tb01606.x","article-title":"Death caused by wasp and bee stings in Denmark 1960-1980","volume":"38","author":"Mosbech","year":"1983","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2004.04.029_BIB25","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1034\/j.1398-9995.2001.t01-1-00001.x","article-title":"A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force","volume":"56","author":"Johansson","year":"2001","journal-title":"Allergy"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674904013983?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674904013983?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T04:55:25Z","timestamp":1758776125000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674904013983"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,8]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,8]]}},"alternative-id":["S0091674904013983"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2004.04.029","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2004,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical features and severity grading of anaphylaxis","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2004.04.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 American Academy of Allergy, Asthma and Immunology. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}