{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:26:03Z","timestamp":1771467963721,"version":"3.50.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2005,3]]},"DOI":"10.1016\/j.jaci.2004.11.005","type":"journal-article","created":{"date-parts":[[2005,1,8]],"date-time":"2005-01-08T22:16:39Z","timestamp":1105222599000},"page":"541-547","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":73,"title":["Rhinophototherapy: A new therapeutic tool for the management of allergic rhinitis"],"prefix":"10.1016","volume":"115","author":[{"given":"Andrea I.","family":"Koreck","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsanett","family":"Csoma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laszlo","family":"Bodai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferenc","family":"Ignacz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Szabo","family":"Kenderessy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edit","family":"Kadocsa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabor","family":"Szabo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsolt","family":"Bor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Erdei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barnabas","family":"Szony","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Homey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Attila","family":"Dobozy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lajos","family":"Kemeny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2004.11.005_bib1","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1056\/NEJM200101043440106","article-title":"Allergy and allergic diseases: first of two parts","volume":"344","author":"Kay","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2004.11.005_bib2","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1067\/mai.2003.68","article-title":"Direct costs of allergic rhinitis in the United States: estimates from the 1996 Medical Expenditure Panel Survey","volume":"111","author":"Law","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.11.005_bib3","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1067\/mai.2003.1592","article-title":"Rhinitis and asthma: evidence for respiratory system integration","volume":"111","author":"Togias","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.11.005_bib4","doi-asserted-by":"crossref","first-page":"863","DOI":"10.2165\/00002018-200326120-00003","article-title":"Safety and tolerability profiles of intranasal antihistamines and intranasal corticosteroids in the treatment of allergic rhinitis","volume":"26","author":"Salib","year":"2003","journal-title":"Drug Saf"},{"key":"10.1016\/j.jaci.2004.11.005_bib5","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1172\/JCI8205","article-title":"IgE in asthma and atopy: cellular and molecular connections","volume":"104","author":"Oettgen","year":"1999","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2004.11.005_bib6","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1164\/ajrccm.151.6.7767538","article-title":"Cytokine immunoreactivity in seasonal rhinitis: regulation by a topical corticosteroid","volume":"151","author":"Bradding","year":"1995","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2004.11.005_bib7","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1159\/000237048","article-title":"Mucosal cytokine expression in allergic rhinitis","volume":"107","author":"Howarth","year":"1995","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jaci.2004.11.005_bib8","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1080\/10408369991239277","article-title":"Advances in the immunobiology of eosinophils and their role in disease","volume":"36","author":"Walsh","year":"1999","journal-title":"Crit Rev Clin Lab Sci"},{"issue":"suppl 1","key":"10.1016\/j.jaci.2004.11.005_bib9","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1046\/j.1365-2222.2000.00093.x","article-title":"The role of mast cells and basophils in inflammation","volume":"30","author":"Holgate","year":"2000","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2004.11.005_bib10","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1172\/JCI119311","article-title":"Nasal mast cells in perennial allergic rhinitis exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells","volume":"99","author":"Pawankar","year":"1997","journal-title":"J Clin Invest"},{"issue":"suppl 64","key":"10.1016\/j.jaci.2004.11.005_bib11","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1034\/j.1398-9995.2000.00802.x","article-title":"Allergic rhinitis: not purely a histamine-related disease","volume":"55","author":"Howarth","year":"2000","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2004.11.005_bib12","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1016\/S0140-6736(05)63945-1","article-title":"308 nm UVB excimer laser for psoriasis","volume":"350","author":"Bonis","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.jaci.2004.11.005_bib13","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/1011-1344(94)07033-4","article-title":"The clinical relevance of immunosuppression by UV irradiation","volume":"24","author":"Vermeer","year":"1994","journal-title":"J Photochem Photobiol B"},{"key":"10.1016\/j.jaci.2004.11.005_bib14","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0190-9622(90)70006-4","article-title":"Combined UVA-UVB versus UVB phototherapy for atopic dermatitis: a paired-comparison study","volume":"22","author":"Jenkler","year":"1989","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaci.2004.11.005_bib15","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0738-081X(02)00364-4","article-title":"Phototherapy of atopic dermatitis","volume":"21","author":"Scheinfeld","year":"2003","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.jaci.2004.11.005_bib16","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/BF00417336","article-title":"Effect of a single UVB or PUVA exposure on immediate and delayed skin hypersensitivity reactions in humans: correlation to erythemal response and Langerhans cell depletion","volume":"275","author":"Kalimo","year":"1983","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.jaci.2004.11.005_bib17","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1046\/j.1365-2567.1999.00801.x","article-title":"UVB exposure-induced systemic modulation of Th1- and Th2-mediated immune responses","volume":"97","author":"Garssen","year":"1999","journal-title":"Immunology"},{"key":"10.1016\/j.jaci.2004.11.005_bib18","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1046\/j.1523-1747.2002.01845.x","article-title":"Mechanisms underlying the suppression of established immune responses by ultraviolet radiation","volume":"119","author":"Nghiem","year":"2002","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2004.11.005_bib19","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1084\/jem.189.4.711","article-title":"312 Nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriasis lesions","volume":"189","author":"Ozawa","year":"1999","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2004.11.005_bib20","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S1011-1344(02)00280-4","article-title":"Xenon chloride ultraviolet B laser is more effective in treating psoriasis and in inducing T cell apoptosis than narrow-band ultraviolet B","volume":"67","author":"Novak","year":"2002","journal-title":"J Photochem Photobiol B"},{"key":"10.1016\/j.jaci.2004.11.005_bib21","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S1011-1344(04)00121-6","article-title":"Inhibition of immediate types hypersensitivity reaction by combined irradiation with ultraviolet and visible light","volume":"77","author":"Koreck","year":"2004","journal-title":"J Photochem Photobiol B"},{"key":"10.1016\/j.jaci.2004.11.005_bib22","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jphotobiol.2004.05.001","article-title":"Intranasal phototherapy with xenon chlorid ultraviolet B laser impoves allergic rhinitis","volume":"75","author":"Csoma","year":"2004","journal-title":"J Photochem Photobiol B"},{"key":"10.1016\/j.jaci.2004.11.005_bib23","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1046\/j.0022-202x.2001.01470.x","article-title":"Skin test results but not serology reflect immediate type respiratory sensitivity: a study performed with recombinant allergen molecules","volume":"117","author":"Niederberger","year":"2001","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2004.11.005_bib24","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1056\/NEJM199908123410702","article-title":"Long-term clinical efficacy of grass-pollen immunotherapy","volume":"341","author":"Durham","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2004.11.005_bib25","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1067\/mai.2000.108430","article-title":"Mechanism of topical glucocorticoid treatment of hay fever: IL-5 and eosinophil activation during natural allergen exposure are suppressed, but IL-4, IL-6, and IgE antibody production are unaffected","volume":"106","author":"Kita","year":"2000","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.11.005_bib26","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1034\/j.1398-9995.1999.00917.x","article-title":"Determination of the allergenic activity of birch pollen and apple prick test solutions by measurement of \u03b2-hexosaminidase release from RBL-2H3 cells: comparison with classical methods in allergen standardization","volume":"54","author":"Hoffmann","year":"1999","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2004.11.005_bib27","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1111\/j.1365-2222.1997.tb00735.x","article-title":"Mechanisms of human eosinophil survival and apoptosis","volume":"27","author":"Walsh","year":"1997","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2004.11.005_bib28","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1165\/ajrcmb\/9.4.356","article-title":"T cells are the principal source of interleukin-5 mRNA in allergen-induced rhinitis","volume":"9","author":"Ying","year":"1993","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jaci.2004.11.005_bib29","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1067\/mai.2001.115483","article-title":"Grass pollen immunotherapy: symptomatic improvement correlates with reductions in eosinophils and IL-5 mRNA expression in the nasal mucosa during the pollen season","volume":"107","author":"Wilson","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.11.005_bib30","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1067\/mai.2000.108111","article-title":"Topical steroid treatment of allergic rhinitis decreases nasal fluid TH2 cytokines, eosinophils, eosinophil cationic protein, and IgE but has no significant effect on IFN-gamma, IL-1beta, TNF-alpha, or neutrophils","volume":"106","author":"Benson","year":"2000","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.11.005_bib31","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1067\/mai.2003.179","article-title":"Modulation of allergic response in nasal mucosa by antisense oligodeoxynucleotides for IL-4","volume":"111","author":"Fiset","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.11.005_bib32","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/S0091-6749(98)70340-9","article-title":"IL-4-induced apoptosis in peripheral blood eosinophils","volume":"102","author":"Wedi","year":"1998","journal-title":"J Allergy Clin Immunol"},{"issue":"suppl 4","key":"10.1016\/j.jaci.2004.11.005_bib33","doi-asserted-by":"crossref","first-page":"S42","DOI":"10.1016\/S0091-6749(03)01876-1","article-title":"H1-Antihistamines: more relevant than ever in the treatment of allergic disorders","volume":"112","author":"Simons","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2004.11.005_bib34","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/0006-2952(94)90478-2","article-title":"In vitro inhibition, by loratadine and descarboxyethoxyloratadine, of histamine release from human basophils, and of histamine release and intracellular calcium fluxes in rat basophilic leukemia cells (RBL-2H3)","volume":"47","author":"Berthon","year":"1994","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.jaci.2004.11.005_bib35","doi-asserted-by":"crossref","first-page":"667","DOI":"10.4049\/jimmunol.147.2.667","article-title":"Hydrocortisone inhibits rat basophilic leukemia cell mediator release induced by neutrophil-derived histamine releasing activity as well as by anti-IgE","volume":"147","author":"White","year":"1991","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2004.11.005_bib36","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1046\/j.1468-3083.2003.00679.x","article-title":"In vitro effects of ultraviolet A on histamine release from human basophils","volume":"17","author":"Monfrecola","year":"2003","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.jaci.2004.11.005_bib37","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1562\/0031-8655(2003)077<0531:IOUUAU>2.0.CO;2","article-title":"Influence of UVB, UVA and UVA1 irradiation on histamine release from human basophils and mast cells in vitro in the presence and absence of antioxidants","volume":"77","author":"Kronauer","year":"2003","journal-title":"Photochem Photobiol"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009167490403043X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009167490403043X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T04:57:08Z","timestamp":1758776228000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S009167490403043X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["S009167490403043X"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2004.11.005","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2005,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rhinophototherapy: A new therapeutic tool for the management of allergic rhinitis","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2004.11.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 American Academy of Allergy, Asthma and Immunology. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}