{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T03:39:43Z","timestamp":1768621183987,"version":"3.49.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T00:00:00Z","timestamp":1164931200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T00:00:00Z","timestamp":1164931200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2006,12]]},"DOI":"10.1016\/j.jaci.2006.07.051","type":"journal-article","created":{"date-parts":[[2006,9,26]],"date-time":"2006-09-26T08:02:59Z","timestamp":1159257779000},"page":"1265-1270","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["Endotoxin exposure, wheezing, and rash in infancy in a New Zealand birth cohort"],"prefix":"10.1016","volume":"118","author":[{"given":"Julie","family":"Gillespie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristin","family":"Wickens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rob","family":"Siebers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippa","family":"Howden-Chapman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Town","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Epton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Penny","family":"Fitzharris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Fishwick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Crane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"the New Zealand Asthma and Allergy Birth Cohort Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2006.07.051_bib1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.prrv.2004.01.007","article-title":"Asthma phenotypes in childhood: lessons from an epidemiological approach","volume":"5","author":"Stein","year":"2004","journal-title":"Paediatr Respir Rev"},{"key":"10.1016\/j.jaci.2006.07.051_bib2","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1056\/NEJM199501193320301","article-title":"Asthma and wheezing in the first six years of life","volume":"332","author":"Martinez","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2006.07.051_bib3","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1046\/j.1365-2222.2003.01665.x","article-title":"Early endotoxin exposure and atopy development in infants: results of a birth cohort study","volume":"33","author":"Bolte","year":"2003","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2006.07.051_bib4","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1164\/ajrccm.163.2.2002088","article-title":"House dust endotoxin and wheeze in the first year of life","volume":"163","author":"Park","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2006.07.051_bib5","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/j.jaci.2006.02.002","article-title":"Does early indoor microbial exposure reduce the risk of asthma? the prevention and incidence of asthma and mite allergy birth cohort study","volume":"117","author":"Douwes","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2006.07.051_bib6","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1046\/j.1365-2222.2000.00959.x","article-title":"Exposure to endotoxin or other bacterial components might protect against the development of atopy","volume":"30","author":"von Mutius","year":"2000","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2006.07.051_bib7","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1056\/NEJMoa020057","article-title":"Environmental exposure to endotoxin and its relation to asthma in school-age children","volume":"347","author":"Braun-Fahrlander","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2006.07.051_bib8","first-page":"134","article-title":"Endotoxin activity of a house dust extract","volume":"35","author":"Peterson","year":"1964","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2006.07.051_bib9","first-page":"57","article-title":"Bronchial reactivity among cotton workers in relation to dust and endotoxin exposure","volume":"37","author":"Rylander","year":"1993","journal-title":"Ann Occup Hyg"},{"key":"10.1016\/j.jaci.2006.07.051_bib10","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1136\/thx.47.4.288","article-title":"Relationship between the bronchial obstructive response to inhaled lipopolysaccharide and bronchial responsiveness to histamine","volume":"47","author":"Michel","year":"1992","journal-title":"Thorax"},{"key":"10.1016\/j.jaci.2006.07.051_bib11","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1164\/ajrccm.156.4.97-02002","article-title":"Dose-response relationship to inhaled endotoxin in normal subjects","volume":"156","author":"Michel","year":"1997","journal-title":"Am\u00a0J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2006.07.051_bib12","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1164\/ajrccm\/146.2.352","article-title":"Inflammatory response to acute inhalation of endotoxin in asthmatic patients","volume":"146","author":"Michel","year":"1992","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.jaci.2006.07.051_bib13","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1600-0668.2004.00253.x","article-title":"Comparison of two dust collection methods for reservoir indoor allergens and endotoxin on carpets and mattresses","volume":"14","author":"Wickens","year":"2004","journal-title":"Indoor Air"},{"key":"10.1016\/j.jaci.2006.07.051_bib14","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.1365-2133.1994.tb08530.x","article-title":"The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis, I: derivation of a minimum set of discriminators for atopic dermatitis","volume":"131","author":"Williams","year":"1994","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2006.07.051_bib15","unstructured":"Salmond C, Crampton P: NZDep 2001 index of deprivation. Department of Public Health, Wellington School of Medicine and Health Sciences; 2001. Available at: http:\/\/www.moh.govt.nz\/moh.nsh\/Files\/phi-research-report\/$file\/phi-research-report.pdf. Accessed November 28, 2005."},{"key":"10.1016\/j.jaci.2006.07.051_bib16","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.jaci.2004.11.021","article-title":"Endotoxin and the lung: Insight into the host-environment interaction","volume":"115","author":"Singh","year":"2005","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2006.07.051_bib17","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0923-1811(98)00016-4","article-title":"Epidermal signal transduction and transcription factor activation in activated keratinocytes","volume":"17","author":"Tomic-Canic","year":"1998","journal-title":"J Dermatol Sci"},{"key":"10.1016\/j.jaci.2006.07.051_bib18","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1046\/j.1523-1747.2002.01847.x","article-title":"Human keratinocytes express functional CD14 and Toll-like receptor 4","volume":"119","author":"Song","year":"2002","journal-title":"J\u00a0Invest Dermatol"},{"issue":"suppl 48","key":"10.1016\/j.jaci.2006.07.051_bib19","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1111\/j.1398-9995.1998.tb05006.x","article-title":"House-dust mite hypersensitivity, eczema, and other non-pulmonary manifestations of allergy","volume":"53","author":"Tupker","year":"1998","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2006.07.051_bib20","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1034\/j.1398-9995.2001.056008797.x","article-title":"Allergy to lipopolysaccaride?","volume":"56","author":"Barber","year":"2001","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2006.07.051_bib21","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1007\/s00420-003-0489-7","article-title":"Health effects associated with indoor storage of organic waste","volume":"77","author":"Herr","year":"2004","journal-title":"Int Arch Occup Environ Health"},{"key":"10.1016\/j.jaci.2006.07.051_bib22","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1046\/j.1365-2133.1998.02121.x","article-title":"Community validation of the United Kingdom diagnostic criteria for atopic dermatitis in Romanian schoolchildren","volume":"138","author":"Popescu","year":"1998","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2006.07.051_bib23","unstructured":"Statistics New Zealand. December 2001. Available at: http:\/\/www.stats.govt.nz\/datasets\/population\/census-of-population-and-dwellings.htm. Accessed May 3, 2006."},{"key":"10.1016\/j.jaci.2006.07.051_bib24","series-title":"Child to adult: the Dunedin Multidisciplinary Health and Development Study","author":"Silva","year":"1996"},{"key":"10.1016\/j.jaci.2006.07.051_bib25","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S0091-6749(98)70016-8","article-title":"Biological\u00a0pollution in infant bedding in New Zealand: high allergen exposure during a vulnerable period","volume":"102","author":"Sawyer","year":"1998","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2006.07.051_bib26","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/S1081-1206(10)62367-8","article-title":"A comparison of two skin test methodologies and allergens from two different manufacturers","volume":"88","author":"Rhodius","year":"2002","journal-title":"Ann Allergy\u00a0Asthma Immunol"},{"key":"10.1016\/j.jaci.2006.07.051_bib27","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1111\/j.1398-9995.1994.tb01124.x","article-title":"Influence of skin prick test criteria on estimation of prevalence and incidence of allergic sensitization in children","volume":"49","author":"Meinert","year":"1994","journal-title":"Allergy"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674906017040?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674906017040?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T05:06:25Z","timestamp":1758776785000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674906017040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["S0091674906017040"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2006.07.051","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2006,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endotoxin exposure, wheezing, and rash in infancy in a New Zealand birth cohort","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2006.07.051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 American Academy of Allergy, Asthma and Immunology. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}