{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T18:18:09Z","timestamp":1791310689217,"version":"4.3.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2007,10,1]],"date-time":"2007-10-01T00:00:00Z","timestamp":1191196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,10,1]],"date-time":"2007-10-01T00:00:00Z","timestamp":1191196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.1016\/j.jaci.2007.06.012","type":"journal-article","created":{"date-parts":[[2007,8,9]],"date-time":"2007-08-09T07:38:50Z","timestamp":1186645130000},"page":"885-891","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":79,"title":["Transmembrane activator and calcium modulator and cyclophilin ligand interactor enhances CD40-driven plasma cell differentiation"],"prefix":"10.1016","volume":"120","author":[{"given":"Emanuela","family":"Castigli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen A.","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdallah","family":"Elkhal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esra","family":"Ozcan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilit","family":"Garibyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raif S.","family":"Geha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2007.06.012_bib1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1084\/jem.20032000","article-title":"TACI and BAFF-R mediate isotype switching in B cells","volume":"201","author":"Castigli","year":"2005","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2007.06.012_bib2","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1038\/ni829","article-title":"DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL","volume":"3","author":"Litinskiy","year":"2002","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaci.2007.06.012_bib3","doi-asserted-by":"crossref","first-page":"4479","DOI":"10.4049\/jimmunol.173.7.4479","article-title":"CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10","volume":"173","author":"He","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2007.06.012_bib4","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1038\/ni1357","article-title":"Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination","volume":"7","author":"Klein","year":"2006","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaci.2007.06.012_bib5","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/S1074-7613(03)00267-X","article-title":"Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells","volume":"19","author":"Shapiro-Shelef","year":"2003","journal-title":"Immunity"},{"key":"10.1016\/j.jaci.2007.06.012_bib6","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/35085509","article-title":"Plasma cell differentiation requires the transcription factor XBP-1","volume":"412","author":"Reimold","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.jaci.2007.06.012_bib7","doi-asserted-by":"crossref","first-page":"7703","DOI":"10.4049\/jimmunol.174.12.7703","article-title":"A role for c-fos\/activator protein 1 in B lymphocyte terminal differentiation","volume":"174","author":"Ohkubo","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2007.06.012_bib8","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1084\/jem.190.12.1837","article-title":"Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4","volume":"190","author":"Gupta","year":"1999","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2007.06.012_bib9","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1038\/ng1601","article-title":"TACI is mutant in common variable immunodeficiency and IgA deficiency","volume":"37","author":"Castigli","year":"2005","journal-title":"Nat Genet"},{"key":"10.1016\/j.jaci.2007.06.012_bib10","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1038\/ng1600","article-title":"Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans","volume":"37","author":"Salzer","year":"2005","journal-title":"Nat Genet"},{"key":"10.1016\/j.jaci.2007.06.012_bib11","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1038\/ng0407-430","article-title":"Reexamining the role of TACI coding variants in common variable immunodeficiency and selective IgA","volume":"39","author":"Castigli","year":"2007","journal-title":"Nat Genet"},{"key":"10.1016\/j.jaci.2007.06.012_bib12","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1038\/nri1713","article-title":"Molecular defects in T- and B-cell primary immunodeficiency diseases","volume":"5","author":"Cunningham-Rundles","year":"2005","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jaci.2007.06.012_bib13","doi-asserted-by":"crossref","first-page":"4067","DOI":"10.1128\/MCB.21.12.4067-4074.2001","article-title":"B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses","volume":"21","author":"Xu","year":"2001","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jaci.2007.06.012_bib14","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S1074-7613(02)00394-1","article-title":"The binding site for TRAF2 and TRAF3 but not for TRAF6 is essential for CD40-mediated immunoglobulin class switching","volume":"17","author":"Jabara","year":"2002","journal-title":"Immunity"},{"key":"10.1016\/j.jaci.2007.06.012_bib15","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0092-8674(00)00078-7","article-title":"Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme","volume":"102","author":"Muramatsu","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.jaci.2007.06.012_bib16","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/29.9.e45","article-title":"A new mathematical model for relative quantification in real-time RT-PCR","volume":"29","author":"Pfaffl","year":"2001","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jaci.2007.06.012_bib17","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/sj.cdd.4401647","article-title":"Heparan sulfate proteoglycan binding promotes APRIL-induced tumor cell proliferation","volume":"12","author":"Hendriks","year":"2005","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.jaci.2007.06.012_bib18","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1084\/jem.20042309","article-title":"Identification of proteoglycans as the APRIL-specific binding partners","volume":"201","author":"Ingold","year":"2005","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.jaci.2007.06.012_bib19","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/ni1016","article-title":"Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation","volume":"5","author":"Hasbold","year":"2004","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaci.2007.06.012_bib20","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S1471-4906(01)02111-1","article-title":"Mechanism and control of class-switch recombination","volume":"23","author":"Manis","year":"2002","journal-title":"Trends Immunol"},{"key":"10.1016\/j.jaci.2007.06.012_bib21","doi-asserted-by":"crossref","first-page":"4213","DOI":"10.4049\/jimmunol.169.8.4213","article-title":"The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity","volume":"169","author":"Minges Wols","year":"2002","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2007.06.012_bib22","doi-asserted-by":"crossref","first-page":"2961","DOI":"10.1182\/blood-2006-08-041772","article-title":"TACI regulates IgA production by APRIL in collaboration with HSPG","volume":"109","author":"Sakurai","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.jaci.2007.06.012_bib23","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1084\/jem.20031330","article-title":"BCMA is essential for the survival of long-lived bone marrow plasma cells","volume":"199","author":"O'Connor","year":"2004","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2007.06.012_bib24","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.immuni.2006.07.009","article-title":"Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation","volume":"25","author":"Sciammas","year":"2006","journal-title":"Immunity"},{"key":"10.1016\/j.jaci.2007.06.012_bib25","doi-asserted-by":"crossref","first-page":"6736","DOI":"10.4049\/jimmunol.176.11.6736","article-title":"APRIL and BAFF promote increased viability of replicating human B2 cells via mechanism involving cyclooxygenase 2","volume":"176","author":"Mongini","year":"2006","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2007.06.012_bib26","doi-asserted-by":"crossref","first-page":"7394","DOI":"10.4049\/jimmunol.173.12.7394","article-title":"Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation","volume":"173","author":"Ni","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2007.06.012_bib27","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1084\/jem.192.1.137","article-title":"TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation","volume":"192","author":"Xia","year":"2000","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2007.06.012_bib28","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.jaci.2005.01.020","article-title":"Jun N-terminal kinase is essential for CD40-mediated IgE class switching in B cells","volume":"115","author":"Jabara","year":"2005","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2007.06.012_bib29","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1038\/ni792","article-title":"The CD40-TRAF6 axis controls affinity maturation and the generation of long-lived plasma cells","volume":"3","author":"Ahonen","year":"2002","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaci.2007.06.012_bib30","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/eji.200636623","article-title":"TACI attenuates antibody production costimulated by BAFF-R and CD40","volume":"37","author":"Sakurai","year":"2007","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jaci.2007.06.012_bib31","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1073\/pnas.91.3.1099","article-title":"CD40 ligand expression is defective in a subset of patients with common variable immunodeficiency","volume":"91","author":"Farrington","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jaci.2007.06.012_bib32","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S1074-7613(01)00130-3","article-title":"Regulation of the T-independent humoral response by TACI","volume":"14","author":"von Bulow","year":"2001","journal-title":"Immunity"},{"key":"10.1016\/j.jaci.2007.06.012_bib33","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1002\/eji.200635956","article-title":"BAFF costimulation of Toll-like receptor-activated B-1 cells","volume":"36","author":"Ng","year":"2006","journal-title":"Eur J Immunol"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674907011943?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674907011943?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T05:09:07Z","timestamp":1758776947000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674907011943"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,10]]}},"alternative-id":["S0091674907011943"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2007.06.012","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2007,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transmembrane activator and calcium modulator and cyclophilin ligand interactor enhances CD40-driven plasma cell differentiation","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2007.06.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}