{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T11:22:28Z","timestamp":1770463348307,"version":"3.49.0"},"reference-count":10,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2008,3]]},"DOI":"10.1016\/j.jaci.2007.09.038","type":"journal-article","created":{"date-parts":[[2007,12,26]],"date-time":"2007-12-26T11:24:29Z","timestamp":1198668269000},"page":"769-770","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":97,"title":["Genetic polymorphism regulating ORM1-like 3\u00a0(Saccharomyces cerevisiae) expression is associated with\u00a0childhood atopic asthma in a Japanese population"],"prefix":"10.1016","volume":"121","author":[{"given":"Tomomitsu","family":"Hirota","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michishige","family":"Harada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masafumi","family":"Sakashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Doi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiko","family":"Miyatake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimie","family":"Fujita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadao","family":"Enomoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motohiro","family":"Ebisawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigemi","family":"Yoshihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emiko","family":"Noguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirohisa","family":"Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayumi","family":"Tamari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2007.09.038_bib1","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1038\/nri1500","article-title":"The immunogenetics of asthma and eczema: a new focus on the epithelium","volume":"4","author":"Cookson","year":"2004","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jaci.2007.09.038_bib2","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/nature06014","article-title":"Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma","volume":"448","author":"Moffatt","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.jaci.2007.09.038_bib3","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2002-3-6-research0027","article-title":"ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins","volume":"3","author":"Hjelmqvist","year":"2002","journal-title":"Genome Biol"},{"key":"10.1016\/j.jaci.2007.09.038_bib4","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1365-2222.2005.02163.x","article-title":"Mechanisms of respiratory virus-induced asthma exacerbations","volume":"35","author":"Contoli","year":"2005","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2007.09.038_bib5","series-title":"Epidemiology and diagnosis of virus-induced asthma exacerbations","first-page":"43","article-title":"Respiratory infections in allergy and asthma","author":"Pattemore","year":"2003"},{"key":"10.1016\/j.jaci.2007.09.038_bib6","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1136\/bmj.310.6989.1225","article-title":"Community study of role of viral infections in exacerbations of asthma in 9-11 year old children","volume":"310","author":"Johnston","year":"1995","journal-title":"BMJ"},{"key":"10.1016\/j.jaci.2007.09.038_bib7","first-page":"425","article-title":"Guidelines for the diagnosis and management of asthma. National Asthma Education Program, Expert Panel Report","volume":"88","author":"National Heart, Lung, and Blood Institute","year":"1991","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2007.09.038_bib8","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.jaci.2005.06.010","article-title":"Functional haplotypes of IL-12B are associated with childhood atopic asthma","volume":"116","author":"Hirota","year":"2005","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2007.09.038_bib9","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1111\/j.1365-2222.2007.02768.x","article-title":"Transforming growth factor-beta(2) polymorphisms are associated with childhood atopic asthma","volume":"37","author":"Hatsushika","year":"2007","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2007.09.038_bib10","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.bbrc.2006.03.102","article-title":"A functional polymorphism in MMP-9 is associated with childhood atopic asthma","volume":"344","author":"Nakashima","year":"2006","journal-title":"Biochem Biophys Res Commun"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674907018325?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674907018325?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T05:12:06Z","timestamp":1758777126000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674907018325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["S0091674907018325"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2007.09.038","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2008,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genetic polymorphism regulating ORM1-like 3\u00a0(Saccharomyces cerevisiae) expression is associated with\u00a0childhood atopic asthma in a Japanese population","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2007.09.038","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}