{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T00:49:43Z","timestamp":1791074983501,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.jaci.2011.03.026","type":"journal-article","created":{"date-parts":[[2011,4,19]],"date-time":"2011-04-19T03:40:28Z","timestamp":1303184428000},"page":"1433-1437","source":"Crossref","is-referenced-by-count":20,"title":["New host defense mechanisms against Candida species clarify the basis of clinical phenotypes"],"prefix":"10.1016","volume":"127","author":[{"given":"Suheir","family":"Hanna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amos","family":"Etzoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2011.03.026_bib1","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1097\/ACI.0b013e32833fd74f","article-title":"Chronic mucocutaneous candidiasis and congenital susceptibility to Candida","volume":"10","author":"Glocker","year":"2010","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.03.026_bib2","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.micinf.2010.03.013","article-title":"Host responses to Candida albicans: Th17 cells and mucosal candidiasis","volume":"12","author":"Conti","year":"2010","journal-title":"Microbes Infect"},{"key":"10.1016\/j.jaci.2011.03.026_bib3","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.coi.2010.06.009","article-title":"Inborn errors of mocucotaneous immunity to Candida albicans in humans: a role for IL-17 cytokines?","volume":"22","author":"Puel","year":"2010","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.jaci.2011.03.026_bib4","first-page":"228","article-title":"Chronic tetany and chronic mycelial stomatitis in a child aged four and one half years","volume":"38","author":"Thorpe","year":"1929","journal-title":"Am J Dis Child"},{"key":"10.1016\/j.jaci.2011.03.026_bib5","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/j.1399-302X.2006.00288.x","article-title":"Distinct roles for IL-12p40 and TNF in resistance to oral candidiasis defined by gene-targeting","volume":"21","author":"Farah","year":"2006","journal-title":"Oral Microbiol Immunol"},{"key":"10.1016\/j.jaci.2011.03.026_bib6","doi-asserted-by":"crossref","first-page":"570","DOI":"10.2741\/3263","article-title":"Role of Toll-like receptors in systemic Candida albicans infections","volume":"14","author":"Gil","year":"2009","journal-title":"Front Biosci"},{"key":"10.1016\/j.jaci.2011.03.026_bib7","doi-asserted-by":"crossref","first-page":"129","DOI":"10.3109\/13693780902964339","article-title":"Absence of TLR2 influences survival of neutrophils after infection with Candida albicans","volume":"48","author":"Tessarolli","year":"2010","journal-title":"Med Mycol"},{"key":"10.1016\/j.jaci.2011.03.026_bib8","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1002\/eji.201041252","article-title":"The role of Syk\/Card9 coupled C-type lectins in antifungal immunity","volume":"41","author":"Drummond","year":"2011","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jaci.2011.03.026_bib9","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.it.2010.06.007","article-title":"Innate immune mechanisms for recognition and uptake of Candida species","volume":"31","author":"Netea","year":"2010","journal-title":"Trends Immunol"},{"key":"10.1016\/j.jaci.2011.03.026_bib10","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.immuni.2010.05.001","article-title":"Dectin-2 recognition of alfa mannans and induction of Th17 cell differentiation is essential for host defence against Candida albicans","volume":"32","author":"Saijo","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.jaci.2011.03.026_bib11","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/ni0607-549","article-title":"Antifungal defence turns 17","volume":"8","author":"Palm","year":"2007","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaci.2011.03.026_bib12","doi-asserted-by":"crossref","first-page":"5224","DOI":"10.4049\/jimmunol.1000032","article-title":"CCR5 dictates the equilibrium of proinflammatory IL-17+ and regulatory Foxp3+ T cells in fungal infection","volume":"184","author":"Kroetz","year":"2010","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2011.03.026_bib13","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/nature04753","article-title":"Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells","volume":"441","author":"Bettelli","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.jaci.2011.03.026_bib14","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1038\/nri2586","article-title":"Structure and signalling in the IL-17 receptor family","volume":"9","author":"Gaffen","year":"2009","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jaci.2011.03.026_bib15","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1038\/nature06096","article-title":"Dominant negative mutations in the DNA binding domain of STAT3 cause hyper IgE syndrome","volume":"448","author":"Minegishi","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.jaci.2011.03.026_bib16","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1038\/nature06764","article-title":"Impaired Th17 cell differentiation in subjects with autosomal dominant hyper IgE syndrome","volume":"452","author":"Milner","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.jaci.2011.03.026_bib17","doi-asserted-by":"crossref","DOI":"10.1038\/mi.2011.5","article-title":"New mechanism of oral immunity to mucosal candidiasis in hyper IgE syndrome","author":"Conti","year":"2011","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.jaci.2011.03.026_bib18","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1084\/jem.20091983","article-title":"Autoantibodies against IL17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I","volume":"207","author":"Puel","year":"2010","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2011.03.026_bib19","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1084\/jem.20091669","article-title":"Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17 associated cytokines","volume":"207","author":"Kisard","year":"2010","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2011.03.026_bib20","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/j.jaci.2010.08.027","article-title":"Impaired Th17 responses in patients with chronic mucocutaneous candidiasis with and without autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy","volume":"126","author":"Ng","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.03.026_bib21","first-page":"381","article-title":"Revisiting human IL-12Rbeta1 deficiency","volume":"89","author":"Beaucoudrey","year":"2010","journal-title":"Medicine"},{"key":"10.1016\/j.jaci.2011.03.026_bib22","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1056\/NEJMoa0810719","article-title":"A homozygous CARD9 mutation in a family with susceptibility to fungal infections","volume":"361","author":"Glocker","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2011.03.026_bib23","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1056\/NEJMoa0901053","article-title":"Human Dectin 1 deficiency and mucocutaneous fungal infections","volume":"361","author":"Ferwerda","year":"2009","journal-title":"N Engl J\u00a0Med"},{"key":"10.1016\/j.jaci.2011.03.026_bib24","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1126\/science.1200439","article-title":"Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity","volume":"332","author":"Puel","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.jaci.2011.03.026_bib25","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.1038\/jid.2008.139","article-title":"Patients with chronic mucocutaneous candidiasis exhibit reduced production of Th-17 associated cytokines Il-17 and IL-22","volume":"128","author":"Eyerich","year":"2008","journal-title":"J Invest Dermatol"}],"updated-by":[{"DOI":"10.1016\/j.jaci.2011.06.021","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000}}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674911005057?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674911005057?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,3]],"date-time":"2018-12-03T06:20:36Z","timestamp":1543818036000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674911005057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0091674911005057"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2011.03.026","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}