{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:20:35Z","timestamp":1784546435988,"version":"3.55.0"},"reference-count":73,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1016\/j.jaci.2011.05.042","type":"journal-article","created":{"date-parts":[[2011,7,22]],"date-time":"2011-07-22T19:44:19Z","timestamp":1311363859000},"page":"583-593.e4","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":195,"title":["Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response"],"prefix":"10.1016","volume":"128","author":[{"given":"Suzanne","family":"Tintle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avner","family":"Shemer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayte","family":"Su\u00e1rez-Fari\u00f1as","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Fujita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Gilleaudeau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Sullivan-Whalen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leanne","family":"Johnson-Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Chiricozzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irma","family":"Cardinale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shenghui","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Bowcock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James G.","family":"Krueger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Guttman-Yassky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2011.05.042_bib1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.jaci.2009.11.027","article-title":"Recent insights into atopic dermatitis and implications for management of infectious complications","volume":"125","author":"Boguniewicz","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib2","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1016\/j.jaci.2007.03.006","article-title":"Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis","volume":"119","author":"Guttman-Yassky","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib3","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1111\/1523-1747.ep12371797","article-title":"Improved barrier structure formation in air-exposed human keratinocyte culture systems","volume":"102","author":"Fartasch","year":"1994","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib4","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1016\/j.jaci.2008.01.022","article-title":"Basis for the barrier abnormality in atopic dermatitis: outside-inside-outside pathogenic mechanisms","volume":"121","author":"Elias","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib5","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/ng1767","article-title":"Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis","volume":"38","author":"Palmer","year":"2006","journal-title":"Nat Genet"},{"issue":"Spec No 1","key":"10.1016\/j.jaci.2011.05.042_bib6","doi-asserted-by":"crossref","first-page":"R43","DOI":"10.1093\/hmg\/ddh094","article-title":"The genetics of psoriasis, psoriatic arthritis and atopic dermatitis","volume":"13","author":"Bowcock","year":"2004","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jaci.2011.05.042_bib7","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/j.jaci.2009.09.031","article-title":"Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis","volume":"124","author":"Guttman-Yassky","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib8","doi-asserted-by":"crossref","first-page":"499","DOI":"10.2340\/00015555-0329","article-title":"Analysis of SPINK 5, KLK 7 and FLG genotypes in a French atopic dermatitis cohort","volume":"87","author":"Hubiche","year":"2007","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jaci.2011.05.042_bib9","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1016\/j.jaci.2011.01.054","article-title":"Contrasting pathogenesis of atopic dermatitis and psoriasis\u2014part I: clinical and pathologic concepts","volume":"127","author":"Guttman-Yassky","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib10","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.jaci.2008.05.050","article-title":"Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk","volume":"122","author":"Weidinger","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib11","article-title":"Therapeutic implications of a barrier-based pathogenesis of atopic dermatitis","author":"Elias","year":"2010","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib12","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s11882-009-0041-2","article-title":"Pathogenesis of atopic dermatitis: new developments","volume":"9","author":"Bieber","year":"2009","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.jaci.2011.05.042_bib13","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/j.jaci.2010.12.1124","article-title":"Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities","volume":"127","author":"Suarez-Farinas","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib14","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1016\/j.jaci.2009.03.041","article-title":"IL-22-producing \u201cT22\u201d T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells","volume":"123","author":"Nograles","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib15","doi-asserted-by":"crossref","first-page":"7420","DOI":"10.4049\/jimmunol.181.10.7420","article-title":"Low expression of the IL-23\/Th17 pathway in atopic dermatitis compared to psoriasis","volume":"181","author":"Guttman-Yassky","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib16","doi-asserted-by":"crossref","first-page":"3695","DOI":"10.4049\/jimmunol.174.6.3695","article-title":"IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes","volume":"174","author":"Boniface","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib17","doi-asserted-by":"crossref","first-page":"3091","DOI":"10.1185\/030079907X242593","article-title":"Atopic dermatitis: understanding the disease and its management","volume":"23","author":"Levy","year":"2007","journal-title":"Curr Med Res Opin"},{"key":"10.1016\/j.jaci.2011.05.042_bib18","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jaad.2008.08.048","article-title":"Narrowband ultraviolet B and medium-dose ultraviolet A1 are equally effective in the treatment of moderate to severe atopic dermatitis","volume":"60","author":"Majoie","year":"2009","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib19","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1111\/j.1365-2133.2008.08498.x","article-title":"Gene expression of cytokines in atopic eczema before and after ultraviolet A1 phototherapy","volume":"158","author":"Gambichler","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib20","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/s00403-008-0923-5","article-title":"Management of atopic dermatitis using photo(chemo)therapy","volume":"301","author":"Gambichler","year":"2009","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.jaci.2011.05.042_bib21","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/S0190-9622(99)70076-9","article-title":"Suberythemogenic narrow-band UVB is markedly more effective than conventional UVB in treatment of psoriasis vulgaris","volume":"40","author":"Walters","year":"1999","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib22","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1001\/archderm.139.2.155","article-title":"Narrowband (312-nm) UV-B suppresses interferon gamma and interleukin (IL) 12 and increases IL-4 transcripts: differential regulation of cytokines at the single-cell level","volume":"139","author":"Walters","year":"2003","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib23","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1084\/jem.189.4.711","article-title":"312-nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions","volume":"189","author":"Ozawa","year":"1999","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2011.05.042_bib24","doi-asserted-by":"crossref","first-page":"2654","DOI":"10.1038\/jid.2010.166","article-title":"Effective narrow-band UVB radiation therapy suppresses the IL-23\/IL-17 axis in normalized psoriasis plaques","volume":"130","author":"Johnson-Huang","year":"2010","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib25","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/1523-1747.ep12499782","article-title":"Studies of the effect of cyclosporine in psoriasis in\u00a0vivo: combined effects on activated T lymphocytes and epidermal regenerative maturation","volume":"98","author":"Gottlieb","year":"1992","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib26","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1159\/000247298","article-title":"Severity scoring of atopic dermatitis: the SCORAD index. Consensus Report of the European Task Force on Atopic Dermatitis","volume":"186","year":"1993","journal-title":"Dermatology"},{"key":"10.1016\/j.jaci.2011.05.042_bib27","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1067\/mcp.2001.113989","article-title":"Biomarkers and surrogate endpoints: preferred definitions and conceptual framework","volume":"69","year":"2001","journal-title":"Clin Pharmacol Ther"},{"key":"10.1016\/j.jaci.2011.05.042_bib28","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/j.jaci.2010.03.018","article-title":"Identification of TNF-related apoptosis-inducing ligand and other molecules that distinguish inflammatory from resident dendritic cells in patients with psoriasis","volume":"125","author":"Zaba","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib29","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1111\/j.1365-2222.2009.03241.x","article-title":"Thymic stromal lymphopoietin, OX40-ligand, and interleukin-25 in allergic responses","volume":"39","author":"Wang","year":"2009","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2011.05.042_bib30","first-page":"1092","article-title":"Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways","volume":"159","author":"Nograles","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib31","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/jid.2010.303","article-title":"Core outcome domains for controlled trials and clinical recordkeeping in eczema: international multiperspective Delphi consensus process","volume":"131","author":"Schmitt","year":"2011","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib32","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1111\/j.1365-2133.2006.07481.x","article-title":"Changes of antimicrobial peptide mRNA expression in atopic eczema following phototherapy","volume":"155","author":"Gambichler","year":"2006","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib33","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/S0076-6879(00)19030-5","article-title":"Ultraviolet A-1 irradiation as a tool to study the pathogenesis of atopic dermatitis","volume":"319","author":"Krutmann","year":"2000","journal-title":"Methods Enzymol"},{"key":"10.1016\/j.jaci.2011.05.042_bib34","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1046\/j.1468-3083.2003.00761.x","article-title":"Mechanisms of apoptosis: UVA1-induced immediate and UVB-induced delayed apoptosis in human T cells in\u00a0vitro","volume":"17","author":"Breuckmann","year":"2003","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.jaci.2011.05.042_bib35","doi-asserted-by":"crossref","first-page":"2880","DOI":"10.1038\/jid.2008.169","article-title":"Biopositive effects of low-dose UVB on epidermis: coordinate upregulation of antimicrobial peptides and permeability barrier reinforcement","volume":"128","author":"Hong","year":"2008","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib36","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/sj.jidsp.5640185","article-title":"Mechanisms of ultraviolet (UV) B and UVA phototherapy","volume":"4","author":"Krutmann","year":"1999","journal-title":"J Investig Dermatol Symp Proc"},{"key":"10.1016\/j.jaci.2011.05.042_bib37","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1600-0781.2007.00284.x","article-title":"Fox-P3-positive regulatory T cells are present in the skin of generalized atopic eczema patients and are not particularly affected by medium-dose UVA1 therapy","volume":"23","author":"Schnopp","year":"2007","journal-title":"Photodermatol Photoimmunol Photomed"},{"key":"10.1016\/j.jaci.2011.05.042_bib38","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/S1081-1206(10)60458-9","article-title":"Down-regulation of atopic dermatitis-associated serum chemokines by wet-wrap treatment: a pilot study","volume":"100","author":"Ong","year":"2008","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib39","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.jaci.2010.04.032","article-title":"Low-dose, but not high-dose, cyclosporin A\u00a0promotes regulatory T-cell induction, expansion, or both","volume":"126","author":"Baumgrass","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib40","doi-asserted-by":"crossref","first-page":"e70","DOI":"10.1016\/j.jaad.2010.02.015","article-title":"Differential usefulness of biomarkers thymus and activation-regulated chemokine and soluble CD30 during enteric coated mycophenolate sodium and cyclosporine therapy in atopic dermatitis","volume":"63","author":"Kwakkel-van Erp","year":"2010","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib41","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.jaci.2009.07.056","article-title":"Cyclosporin A\u00a0reduces CD4(+)CD25(+) regulatory T-cell numbers in patients with atopic dermatitis","volume":"124","author":"Hijnen","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib42","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1111\/j.1398-9995.2004.00639.x","article-title":"Cyclosporine treatment decreases the percentage of cutaneous lymphocyte antigen (CLA)(+)CD4(+) T cells in children with severe atopic dermatitis","volume":"59","author":"Lee","year":"2004","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2011.05.042_bib43","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1034\/j.1399-3038.2001.012004216.x","article-title":"Low-dose cyclosporin A\u00a0microemulsion in children with severe atopic dermatitis: clinical and immunological effects","volume":"12","author":"Bunikowski","year":"2001","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib44","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1046\/j.1365-2133.2001.03948.x","article-title":"A rapid flow cytometric assay to detect CD4+ and CD8+ T-helper (Th) 0, Th1 and Th2 cells in whole blood and its application to study cytokine levels in atopic dermatitis before and after cyclosporin therapy","volume":"144","author":"Farrell","year":"2001","journal-title":"Br J Dermatol"},{"issue":"suppl\u00a01","key":"10.1016\/j.jaci.2011.05.042_bib45","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1159\/000053605","article-title":"Overexpression of CD11b on eosinophils in atopic dermatitis: downregulation by cyclosporin A\u00a0and upregulation by interleukin 5","volume":"120","author":"Yamada","year":"1999","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib46","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/j.1365-2133.2006.07609.x","article-title":"The comparative effects of tacrolimus and hydrocortisone in adult atopic dermatitis: an immunohistochemical study","volume":"156","author":"Caproni","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib47","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1111\/j.1365-2230.2006.02214.x","article-title":"Expression of adhesion molecules in atopic dermatitis is reduced by tacrolimus, but not by hydrocortisone butyrate: a randomized immunohistochemical study","volume":"31","author":"Caproni","year":"2006","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib48","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jdermsci.2006.08.004","article-title":"Macrophage-derived chemokine (MDC)\/CCL22 produced by monocyte derived dendritic cells reflects the disease activity in patients with atopic dermatitis","volume":"44","author":"Hashimoto","year":"2006","journal-title":"J Dermatol Sci"},{"key":"10.1016\/j.jaci.2011.05.042_bib49","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jaci.2008.10.031","article-title":"IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response","volume":"123","author":"Eyerich","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib50","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.clim.2007.11.006","article-title":"Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6","volume":"126","author":"Kim","year":"2008","journal-title":"Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib51","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1038\/jid.2008.74","article-title":"Th2 cytokines act on S100\/A11 to downregulate keratinocyte differentiation","volume":"128","author":"Howell","year":"2008","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib52","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.jdermsci.2010.08.013","article-title":"Significant correlation of serum IL-22 levels with CCL17 levels in atopic dermatitis","volume":"61","author":"Hayashida","year":"2011","journal-title":"J Dermatol Sci"},{"key":"10.1016\/j.jaci.2011.05.042_bib53","first-page":"3573","article-title":"Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling","volume":"119","author":"Eyerich","year":"2009","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2011.05.042_bib54","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1016\/j.jaci.2010.07.041","article-title":"Staphylococcal exotoxins are strong inducers of IL-22: a potential role in atopic dermatitis","volume":"126","author":"Niebuhr","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib55","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1111\/j.1751-1097.1996.tb03055.x","article-title":"Cell-mediated immunosuppressive mechanisms induced by UV radiation","volume":"63","author":"Cooper","year":"1996","journal-title":"Photochem Photobiol"},{"key":"10.1016\/j.jaci.2011.05.042_bib56","doi-asserted-by":"crossref","first-page":"66S","DOI":"10.1111\/1523-1747.ep12462236","article-title":"Ultraviolet B-irradiated antigen-presenting cells display altered accessory signaling for T-cell activation: relevance to immune responses initiated in skin","volume":"98","author":"Simon","year":"1992","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib57","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1084\/jem.186.10.1763","article-title":"Evidence that singlet oxygen-induced human T helper cell apoptosis is the basic mechanism of ultraviolet-A radiation phototherapy","volume":"186","author":"Morita","year":"1997","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2011.05.042_bib58","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1001\/archderm.1997.03890480034005","article-title":"Narrowband UV-B produces superior clinical and histopathological resolution of moderate-to-severe psoriasis in patients compared with broadband UV-B","volume":"133","author":"Coven","year":"1997","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib59","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1034\/j.1600-0625.2003.120208.x","article-title":"Ultraviolet-B irradiation decreases IFN-gamma and increases IL-4 expression in psoriatic lesional skin in situ and in cultured dermal T cells derived from these lesions","volume":"12","author":"Piskin","year":"2003","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib60","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s00403-004-0460-9","article-title":"T cells in psoriatic lesional skin that survive conventional therapy with NB-UVB radiation display reduced IFN-gamma expression","volume":"295","author":"Piskin","year":"2004","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.jaci.2011.05.042_bib61","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.4049\/jimmunol.154.4.1956","article-title":"Overexpression of IL-10 in atopic dermatitis. Contrasting cytokine patterns with delayed-type hypersensitivity reactions","volume":"154","author":"Ohmen","year":"1995","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib62","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1111\/j.0022-202X.2005.23776.x","article-title":"Interleukin-10 downregulates anti-microbial peptide expression in atopic dermatitis","volume":"125","author":"Howell","year":"2005","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bib63","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1007\/s000110050500","article-title":"Differential IL-10 receptor gene expression in acute versus chronic atopic eczema. Modulation by immunosuppressive drugs and cytokines in normal cultured keratinocytes","volume":"48","author":"Muschen","year":"1999","journal-title":"Inflamm Res"},{"key":"10.1016\/j.jaci.2011.05.042_bib64","doi-asserted-by":"crossref","first-page":"R7","DOI":"10.1016\/j.jaci.2009.07.012","article-title":"Cytokine modulation of atopic dermatitis filaggrin skin expression","volume":"124","author":"Howell","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib65","doi-asserted-by":"crossref","first-page":"21795","DOI":"10.1073\/pnas.0911472106","article-title":"Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production","volume":"106","author":"Fujita","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jaci.2011.05.042_bib66","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1038\/ni.1767","article-title":"Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells","volume":"10","author":"Duhen","year":"2009","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bib67","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jphotobiol.2005.08.011","article-title":"Narrow-band UVB induces apoptosis in human keratinocytes","volume":"82","author":"Aufiero","year":"2006","journal-title":"J Photochem Photobiol B"},{"key":"10.1016\/j.jaci.2011.05.042_bibE1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.2165\/00128071-200910020-00004","article-title":"Throwing a light on photosensitivity in atopic dermatitis: a retrospective study","volume":"10","author":"ten Berge","year":"2009","journal-title":"Am J Clin Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bibE2","first-page":"23","article-title":"Consensus Report of the European Task Force on Atopic Dermatitis","volume":"186","year":"1993","journal-title":"Dermatology"},{"key":"10.1016\/j.jaci.2011.05.042_bibE3","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1111\/j.1365-2133.2007.08112.x","article-title":"Practical issues on interpretation of scoring atopic dermatitis: the SCORAD index, objective SCORAD and the three-item severity score","volume":"157","author":"Oranje","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2011.05.042_bibE4","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/j.jaci.2009.09.031","article-title":"Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis","volume":"124","author":"Guttman-Yassky","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2011.05.042_bibE5","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1186\/1471-2105-6-294","article-title":"Harshlight: a \u201ccorrective make-up\u201d program for microarray chips","volume":"6","author":"Suarez-Farinas","year":"2005","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.jaci.2011.05.042_bibE6","doi-asserted-by":"crossref","DOI":"10.2202\/1544-6115.1027","article-title":"Linear models and empirical Bayes methods for assessing differential expression in microarray experiments","volume":"3","author":"Smyth","year":"2004","journal-title":"Stat Appl Genet Mol Biol"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674911009201?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674911009201?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T08:31:36Z","timestamp":1758789096000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674911009201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":73,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S0091674911009201"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2011.05.042","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2011.05.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}