{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T19:28:33Z","timestamp":1792524513704,"version":"4.5.0"},"reference-count":66,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1016\/j.jaci.2012.12.1562","type":"journal-article","created":{"date-parts":[[2013,1,30]],"date-time":"2013-01-30T03:39:59Z","timestamp":1359517199000},"page":"324-329","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":118,"title":["Vitamin D in allergic disease: Shedding light on a complex problem"],"prefix":"10.1016","volume":"131","author":[{"given":"Beda","family":"Muehleisen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard L.","family":"Gallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2012.12.1562_bib1","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1210\/jc.2011-2218","article-title":"IOM committee members respond to Endocrine Society vitamin D guideline","volume":"97","author":"Rosen","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jaci.2012.12.1562_bib2","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1210\/jc.2011-0385","article-title":"Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline","volume":"96","author":"Holick","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jaci.2012.12.1562_bib3","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1042\/bj3160361","article-title":"Genomic mechanisms involved in the pleiotropic actions of 1,25-dihydroxyvitamin D3","volume":"316","author":"Christakos","year":"1996","journal-title":"Biochem J"},{"key":"10.1016\/j.jaci.2012.12.1562_bib4","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.jsbmb.2010.03.027","article-title":"Differential regulation of epidermal function by VDR coactivators","volume":"121","author":"Bikle","year":"2010","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib5","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1038\/sj.jid.5700624","article-title":"Regulation of human epidermal keratinocyte differentiation by the vitamin D receptor and its coactivators DRIP205, SRC2, and SRC3","volume":"127","author":"Hawker","year":"2007","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib6","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1172\/JCI30142","article-title":"Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism","volume":"117","author":"Schauber","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2012.12.1562_bib7","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1126\/science.1123933","article-title":"Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response","volume":"311","author":"Liu","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.jaci.2012.12.1562_bib8","doi-asserted-by":"crossref","first-page":"104ra2","DOI":"10.1126\/scitranslmed.3003045","article-title":"Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages","volume":"3","author":"Fabri","year":"2011","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jaci.2012.12.1562_bib9","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1096\/fj.04-3284com","article-title":"Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3","volume":"19","author":"Gombart","year":"2005","journal-title":"FASEB J"},{"key":"10.1016\/j.jaci.2012.12.1562_bib10","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.4049\/jimmunol.173.5.2909","article-title":"Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression","volume":"173","author":"Wang","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib11","doi-asserted-by":"crossref","first-page":"135ra66","DOI":"10.1126\/scitranslmed.3003759","article-title":"PTH\/PTHrP and vitamin D control antimicrobial peptide expression and susceptibility to bacterial skin infection","volume":"4","author":"Muehleisen","year":"2012","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jaci.2012.12.1562_bib12","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.jsbmb.2010.02.034","article-title":"Immune-modifying properties of topical vitamin D: focus on dendritic cells and T cells","volume":"121","author":"Gorman","year":"2010","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib13","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/j.1365-2567.2006.02399.x","article-title":"Control of the innate epithelial antimicrobial response is cell-type specific and dependent on relevant microenvironmental stimuli","volume":"118","author":"Schauber","year":"2006","journal-title":"Immunology"},{"key":"10.1016\/j.jaci.2012.12.1562_bib14","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1038\/35106587","article-title":"Innate antimicrobial peptide protects the skin from invasive bacterial infection","volume":"414","author":"Nizet","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.jaci.2012.12.1562_bib15","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/nri3228","article-title":"Epithelial antimicrobial defence of the skin and intestine","volume":"12","author":"Gallo","year":"2012","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib16","doi-asserted-by":"crossref","first-page":"2880","DOI":"10.1038\/jid.2008.169","article-title":"Biopositive effects of low-dose UVB on epidermis: coordinate upregulation of antimicrobial peptides and permeability barrier reinforcement","volume":"128","author":"Hong","year":"2008","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib17","doi-asserted-by":"crossref","first-page":"18890","DOI":"10.1074\/jbc.M110.206110","article-title":"Hormonally active vitamin D3 (1alpha,25-dihydroxycholecalciferol) triggers autophagy in human macrophages that inhibits HIV-1 infection","volume":"286","author":"Campbell","year":"2011","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jaci.2012.12.1562_bib18","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.chom.2009.08.004","article-title":"Vitamin D3 induces autophagy in human monocytes\/macrophages via cathelicidin","volume":"6","author":"Yuk","year":"2009","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jaci.2012.12.1562_bib19","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1086\/525268","article-title":"Vitamin D deficiency is associated with tuberculosis and latent tuberculosis infection in immigrants from sub-Saharan Africa","volume":"46","author":"Gibney","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jaci.2012.12.1562_bib20","doi-asserted-by":"crossref","first-page":"369","DOI":"10.4049\/jimmunol.0902110","article-title":"The host defense peptide cathelicidin is required for NK cell-mediated suppression of tumor growth","volume":"184","author":"Buchau","year":"2010","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib21","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/eji.200425995","article-title":"Vitamin D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns","volume":"36","author":"Sadeghi","year":"2006","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib22","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1365-2567.2009.03222.x","article-title":"1,25-dihydroxyvitamin D3 enhances the ability of transferred CD4+ CD25+ cells to modulate T helper type 2-driven asthmatic responses","volume":"130","author":"Gorman","year":"2010","journal-title":"Immunology"},{"key":"10.1016\/j.jaci.2012.12.1562_bib23","doi-asserted-by":"crossref","first-page":"4443","DOI":"10.4049\/jimmunol.164.9.4443","article-title":"Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells","volume":"164","author":"Piemonti","year":"2000","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib24","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/j.1365-2249.2010.04315.x","article-title":"Regulation of cytokine responses by seasonality of vitamin D status in healthy individuals","volume":"164","author":"Khoo","year":"2011","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib25","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1002\/jnr.20826","article-title":"1,25 Dihydroxyvitamin-D3 modulates JAK-STAT pathway in IL-12\/IFNgamma axis leading to Th1 response in experimental allergic encephalomyelitis","volume":"83","author":"Muthian","year":"2006","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.jaci.2012.12.1562_bib26","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1067\/mai.2000.110101","article-title":"Additive immunosuppressive effects of 1,25-dihydroxyvitamin D3 and corticosteroids on TH1, but not TH2, responses","volume":"106","author":"Jirapongsananuruk","year":"2000","journal-title":"J Allergy Clin Immunol"},{"issue":"suppl","key":"10.1016\/j.jaci.2012.12.1562_bib27","doi-asserted-by":"crossref","first-page":"1704S","DOI":"10.1093\/jn\/125.suppl_6.1704S","article-title":"Immunosuppressive actions of 1,25-dihydroxyvitamin D3: preferential inhibition of Th1 functions","volume":"125","author":"Lemire","year":"1995","journal-title":"J Nutr"},{"key":"10.1016\/j.jaci.2012.12.1562_bib28","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1128\/iai.64.4.1100-1109.1996","article-title":"Induction of common mucosal immunity by hormonally immunomodulated peripheral immunization","volume":"64","author":"Daynes","year":"1996","journal-title":"Infect Immun"},{"key":"10.1016\/j.jaci.2012.12.1562_bib29","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.cyto.2009.12.006","article-title":"No effect of supplementation with cholecalciferol on cytokines and markers of inflammation in overweight and obese subjects","volume":"50","author":"Jorde","year":"2010","journal-title":"Cytokine"},{"key":"10.1016\/j.jaci.2012.12.1562_bib30","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S0091-6749(03)01855-4","article-title":"Dual effects of vitamin D-induced alteration of TH1\/TH2 cytokine expression: enhancing IgE production and decreasing airway eosinophilia in murine allergic airway disease","volume":"112","author":"Matheu","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib31","doi-asserted-by":"crossref","first-page":"3242","DOI":"10.1172\/JCI42388","article-title":"Vitamin D3 attenuates Th2 responses to Aspergillus fumigatus mounted by CD4+ T cells from cystic fibrosis patients with allergic bronchopulmonary aspergillosis","volume":"120","author":"Kreindler","year":"2010","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2012.12.1562_bib32","doi-asserted-by":"crossref","first-page":"e12925","DOI":"10.1371\/journal.pone.0012925","article-title":"1,25-Dihydroxyvitamin D3 inhibits the differentiation and migration of T(H)17 cells to protect against experimental autoimmune encephalomyelitis","volume":"5","author":"Chang","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.jaci.2012.12.1562_bib33","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1084\/jem.20091725","article-title":"Evidence that vitamin D(3) promotes mast cell-dependent reduction of chronic UVB-induced skin pathology in mice","volume":"207","author":"Biggs","year":"2010","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2012.12.1562_bib34","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1111\/j.1365-2222.2009.03301.x","article-title":"Regulatory T cells and asthma","volume":"39","author":"Robinson","year":"2009","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2012.12.1562_bib35","doi-asserted-by":"crossref","first-page":"6071","DOI":"10.4049\/jimmunol.0804064","article-title":"Expansion of antigen-specific regulatory T cells with the topical vitamin d analog calcipotriol","volume":"182","author":"Ghoreishi","year":"2009","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib36","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.intimp.2009.01.024","article-title":"Regulation of cutaneous immunity by the environment: an important role for UV irradiation and vitamin D","volume":"9","author":"Loser","year":"2009","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib37","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1074\/jbc.M110.163790","article-title":"Lineage-specific effects of 1,25-dihydroxyvitamin D(3) on the development of effector CD4 T cells","volume":"286","author":"Palmer","year":"2011","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jaci.2012.12.1562_bib38","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/j.1398-9995.2010.02513.x","article-title":"Targeting the vitamin D receptor inhibits the B cell-dependent allergic immune response","volume":"66","author":"Hartmann","year":"2011","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2012.12.1562_bib39","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.jaci.2008.03.005","article-title":"Asthma and obesity: common early-life influences in the inception of disease","volume":"121","author":"Litonjua","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib40","doi-asserted-by":"crossref","first-page":"20834","DOI":"10.1073\/pnas.0808700106","article-title":"Failure of T cell homing, reduced CD4\/CD8alphaalpha intraepithelial lymphocytes, and inflammation in the gut of vitamin D receptor KO mice","volume":"105","author":"Yu","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jaci.2012.12.1562_bib41","doi-asserted-by":"crossref","first-page":"686","DOI":"10.2353\/ajpath.2010.090998","article-title":"Vitamin D receptor negatively regulates bacterial-stimulated NF-kappaB activity in intestine","volume":"177","author":"Wu","year":"2010","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib42","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/j.jaci.2011.02.015","article-title":"Gut microbiota, probiotics, and vitamin D: interrelated exposures influencing allergy, asthma, and obesity?","volume":"127","author":"Ly","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib43","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1038\/jid.2009.323","article-title":"Vitamin D production after UVB exposure depends on baseline vitamin D and total cholesterol but not on skin pigmentation","volume":"130","author":"Bogh","year":"2010","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib44","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1365-2133.2010.09767.x","article-title":"Narrowband ultraviolet B treatment improves vitamin D balance and alters antimicrobial peptide expression in skin lesions of psoriasis and atopic dermatitis","volume":"163","author":"Vahavihu","year":"2010","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib45","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1111\/j.1398-9995.2008.01865.x","article-title":"Serum 25-hydroxyvitamin D and IgE\u2014a significant but nonlinear relationship","volume":"64","author":"Hypponen","year":"2009","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2012.12.1562_bib46","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.jaci.2011.01.017","article-title":"Vitamin D levels and food and environmental allergies in the United States: results from the National Health and Nutrition Examination Survey 2005-2006","volume":"127","author":"Sharief","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib47","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1164\/rccm.200808-1361OC","article-title":"Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica","volume":"179","author":"Brehm","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2012.12.1562_bib48","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.jaci.2012.01.044","article-title":"Steroid requirements and immune associations with vitamin D are stronger in children than adults with asthma","volume":"129","author":"Goleva","year":"2012","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib49","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1399-3038.2010.01099.x","article-title":"The role of latitude, ultraviolet radiation exposure and vitamin D in childhood asthma and hayfever: an Australian multicenter study","volume":"22","author":"Hughes","year":"2011","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib50","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.jaci.2007.03.049","article-title":"Regional differences in EpiPen prescriptions in the United States: the potential role of vitamin D","volume":"120","author":"Camargo","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib51","doi-asserted-by":"crossref","first-page":"e180","DOI":"10.1542\/peds.2010-0442","article-title":"Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthma","volume":"127","author":"Camargo","year":"2011","journal-title":"Pediatrics"},{"key":"10.1016\/j.jaci.2012.12.1562_bib52","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/sj.ejcn.1602680","article-title":"Maternal vitamin D status during pregnancy and child outcomes","volume":"62","author":"Gale","year":"2008","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.jaci.2012.12.1562_bib53","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1093\/ajcn\/85.3.853","article-title":"Maternal vitamin D intake during pregnancy and early childhood wheezing","volume":"85","author":"Devereux","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jaci.2012.12.1562_bib54","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1111\/j.1365-2222.2009.03234.x","article-title":"Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children","volume":"39","author":"Erkkola","year":"2009","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2012.12.1562_bib55","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1399-3038.2009.00949.x","article-title":"Maternal diet during pregnancy and allergic sensitization in the offspring by 5 yrs of age: a prospective cohort study","volume":"21","author":"Nwaru","year":"2010","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib56","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.jaci.2010.11.001","article-title":"Nutrients and foods for the primary prevention of asthma and allergy: systematic review and meta-analysis","volume":"127","author":"Nurmatov","year":"2011","journal-title":"J Allergy Clin Immunol"},{"issue":"suppl\u00a03","key":"10.1016\/j.jaci.2012.12.1562_bib57","doi-asserted-by":"crossref","first-page":"80","DOI":"10.3109\/14767058.2010.509931","article-title":"Fetal and early postnatal life roots of asthma","volume":"23","author":"De Luca","year":"2010","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.jaci.2012.12.1562_bib58","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1111\/j.1365-2133.2010.10147.x","article-title":"Correlation between serum 25-hydroxyvitamin D levels and severity of atopic dermatitis in children","volume":"164","author":"Peroni","year":"2011","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib59","doi-asserted-by":"crossref","first-page":"28","DOI":"10.2340\/00015555-0541","article-title":"Does vitamin D intake during infancy promote the development of atopic allergy?","volume":"89","author":"Back","year":"2009","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib60","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1196\/annals.1337.013","article-title":"Infant vitamin d supplementation and allergic conditions in adulthood: northern Finland birth cohort 1966","volume":"1037","author":"Hypponen","year":"2004","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.jaci.2012.12.1562_bib61","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1542\/peds.114.1.27","article-title":"Early infant multivitamin supplementation is associated with increased risk for food allergy and asthma","volume":"114","author":"Milner","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.jaci.2012.12.1562_bib62","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.jaci.2006.08.022","article-title":"Early-life supplementation of vitamins A\u00a0and D, in water-soluble form or in peanut oil, and allergic diseases during childhood","volume":"118","author":"Kull","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib63","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.3945\/ajcn.2009.29094","article-title":"Randomized trial of vitamin D supplementation to prevent seasonal influenza A\u00a0in schoolchildren","volume":"91","author":"Urashima","year":"2010","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jaci.2012.12.1562_bib64","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1365-2133.2008.08601.x","article-title":"Randomized controlled trial of vitamin D supplementation for winter-related atopic dermatitis in Boston: a pilot study","volume":"159","author":"Sidbury","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib65","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/j.jaci.2010.12.016","article-title":"Vitamin D supplementation in children may prevent asthma exacerbation triggered by acute respiratory infection","volume":"127","author":"Majak","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2012.12.1562_bib66","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.jaci.2008.08.020","article-title":"Administration of oral vitamin D induces cathelicidin production in atopic individuals","volume":"122","author":"Hata","year":"2008","journal-title":"J Allergy Clin Immunol"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674912035622?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674912035622?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T08:40:51Z","timestamp":1758789651000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674912035622"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":66,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["S0091674912035622"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2012.12.1562","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vitamin D in allergic disease: Shedding light on a complex problem","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2012.12.1562","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}