{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T05:46:05Z","timestamp":1792388765502,"version":"4.4.0"},"reference-count":11,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.jaci.2013.08.015","type":"journal-article","created":{"date-parts":[[2013,9,29]],"date-time":"2013-09-29T13:01:15Z","timestamp":1380459675000},"page":"275-277.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Suppressor of cytokine signaling 3 expression is diminished in sinonasal tissues from patients with chronic rhinosinusitis with nasal polyps"],"prefix":"10.1016","volume":"133","author":[{"given":"Kathryn E.","family":"Hulse","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrina","family":"Chaung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudarshan","family":"Seshadri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydia","family":"Suh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James E.","family":"Norton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roderick G.","family":"Carter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert C.","family":"Kern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David B.","family":"Conley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakesh K.","family":"Chandra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce K.","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anju T.","family":"Peters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Leslie C.","family":"Grammer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen E.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Troy R.","family":"Torgerson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert P.","family":"Schleimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2013.08.015_bib1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/MOO.0b013e3283350053","article-title":"Perspectives on the etiology of chronic rhinosinusitis","volume":"18","author":"Tan","year":"2010","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jaci.2013.08.015_bib2","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jaci.2004.09.029","article-title":"Rhinosinusitis: establishing definitions for clinical research and patient care","volume":"114","author":"Meltzer","year":"2004","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2013.08.015_bib3","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.jaci.2009.10.072","article-title":"Evidence for altered activity of the IL-6 pathway in chronic rhinosinusitis with nasal polyps","volume":"125","author":"Peters","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2013.08.015_bib4","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/j.jaci.2008.03.002","article-title":"Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps","volume":"121","author":"Kato","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2013.08.015_bib5","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.jaci.2013.01.043","article-title":"Chronic rhinosinusitis with nasal polyps is characterized by B-cell inflammation and EBV-induced protein 2 expression","volume":"131","author":"Hulse","year":"2013","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2013.08.015_bib6","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.immuni.2011.12.015","article-title":"Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity","volume":"36","author":"Babon","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.jaci.2013.08.015_bib7","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1038\/nm896","article-title":"SOCS-3 regulates onset and maintenance of T(H)2-mediated allergic responses","volume":"9","author":"Seki","year":"2003","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2013.08.015_bib8","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.jaci.2012.12.671","article-title":"Chronic rhinosinusitis with polyps and without polyps is associated with increased expression of suppressors of cytokine signaling 1 and 3","volume":"131","author":"Park","year":"2013","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2013.08.015_bib9","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.jaci.2008.04.037","article-title":"Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced T(H)17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome","volume":"122","author":"Renner","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2013.08.015_bib10","doi-asserted-by":"crossref","unstructured":"Seshadri S, Rosati M, Lin DC, Carter RG, Norton JE, Choi AW, et\u00a0al. Regional differences in the expression of innate host defense molecules in sinonasal mucosa. J Allergy Clin Immunol [Epub 2013 Jul 26] http:\/\/dx.doi.org\/10.1016\/j.jaci.2013.05.042.","DOI":"10.1016\/j.jaci.2013.05.042"},{"key":"10.1016\/j.jaci.2013.08.015_bib11","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.jaci.2008.07.008","article-title":"Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease","volume":"122","author":"Zhang","year":"2008","journal-title":"J Allergy Clin Immunol"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674913013018?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674913013018?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T08:46:07Z","timestamp":1758789967000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674913013018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["S0091674913013018"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2013.08.015","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Suppressor of cytokine signaling 3 expression is diminished in sinonasal tissues from patients with chronic rhinosinusitis with nasal polyps","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2013.08.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}