{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:07:54Z","timestamp":1791497274304,"version":"4.3.4"},"reference-count":28,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.jaci.2014.12.1936","type":"journal-article","created":{"date-parts":[[2015,2,11]],"date-time":"2015-02-11T00:02:19Z","timestamp":1423612939000},"page":"757-768","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":63,"title":["Tumor necrosis factor superfamily 14 (LIGHT) controls thymic stromal lymphopoietin to drive pulmonary fibrosis"],"prefix":"10.1016","volume":"136","author":[{"given":"Rana","family":"Herro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9785-5272","authenticated-orcid":false,"given":"Ricardo","family":"Da Silva Antunes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelia Roman","family":"Aguilera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Tamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Croft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2014.12.1936_bib1","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1146\/annurev.med.55.091902.103810","article-title":"Mechanisms of pulmonary fibrosis","volume":"55","author":"Thannickal","year":"2004","journal-title":"Annu Rev Med"},{"key":"10.1016\/j.jaci.2014.12.1936_bib2","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/mi.2008.85","article-title":"Pulmonary fibrosis: pathogenesis, etiology and regulation","volume":"2","author":"Wilson","year":"2009","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.jaci.2014.12.1936_bib3","doi-asserted-by":"crossref","first-page":"159","DOI":"10.7326\/0003-4819-152-3-201002020-00007","article-title":"Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies","volume":"152","author":"Rosenbloom","year":"2010","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jaci.2014.12.1936_bib4","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1038\/nm.2807","article-title":"Mechanisms of fibrosis: therapeutic translation for fibrotic disease","volume":"18","author":"Wynn","year":"2012","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2014.12.1936_bib5","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nrrheum.2009.108","article-title":"Connective tissue diseases: immunosuppressive therapy in SSc: what is the target?","volume":"5","author":"Boin","year":"2009","journal-title":"Nat Rev Rheumatol"},{"key":"10.1016\/j.jaci.2014.12.1936_bib6","doi-asserted-by":"crossref","first-page":"5470","DOI":"10.4049\/jimmunol.171.10.5470","article-title":"Eosinophils and T lymphocytes possess distinct roles in bleomycin-induced lung injury and fibrosis","volume":"171","author":"Huaux","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2014.12.1936_bib7","doi-asserted-by":"crossref","first-page":"143","DOI":"10.2332\/allergolint.13-RAI-0663","article-title":"Periostin in allergic inflammation","volume":"63","author":"Izuhara","year":"2014","journal-title":"Allergol Int"},{"key":"10.1016\/j.jaci.2014.12.1936_bib8","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1038\/mi.2009.134","article-title":"The influence of TSLP on the allergic response","volume":"3","author":"Comeau","year":"2010","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.jaci.2014.12.1936_bib9","doi-asserted-by":"crossref","first-page":"8183","DOI":"10.4049\/jimmunol.174.12.8183","article-title":"Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity","volume":"174","author":"Ying","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2014.12.1936_bib10","doi-asserted-by":"crossref","first-page":"2790","DOI":"10.4049\/jimmunol.181.4.2790","article-title":"Expression and cellular provenance of thymic stromal lymphopoietin and chemokines in patients with severe asthma and chronic obstructive pulmonary disease","volume":"181","author":"Ying","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2014.12.1936_bib11","doi-asserted-by":"crossref","first-page":"4867","DOI":"10.4049\/jimmunol.1300588","article-title":"Evidence for a functional thymic stromal lymphopoietin signaling axis in fibrotic lung disease","volume":"191","author":"Datta","year":"2013","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2014.12.1936_bib12","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1084\/jem.20041503","article-title":"Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin","volume":"202","author":"Yoo","year":"2005","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2014.12.1936_bib13","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1038\/nm.2356","article-title":"The tumor necrosis factor family member light is a target for asthmatic airway remodeling","volume":"17","author":"Doherty","year":"2011","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2014.12.1936_bib14","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.biocel.2007.08.011","article-title":"The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?","volume":"40","author":"Moeller","year":"2008","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.jaci.2014.12.1936_bib15","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1084\/jem.20020215","article-title":"Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis","volume":"195","author":"Scheu","year":"2002","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2014.12.1936_bib16","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1172\/JCI200522982","article-title":"The role of herpesvirus entry mediator as a negative regulator of T cell-mediated responses","volume":"115","author":"Wang","year":"2005","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2014.12.1936_bib17","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1128\/MCB.24.6.2584-2592.2004","article-title":"Absence of an essential role for thymic stromal lymphopoietin receptor in murine B-cell development","volume":"24","author":"Carpino","year":"2004","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jaci.2014.12.1936_bib18","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1172\/JCI27083","article-title":"Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis","volume":"116","author":"Anand","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2014.12.1936_bib19","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1172\/JCI19133","article-title":"Inhibition of airway remodeling in IL-5-deficient mice","volume":"113","author":"Cho","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2014.12.1936_bib20","doi-asserted-by":"crossref","first-page":"e51268","DOI":"10.1371\/journal.pone.0051268","article-title":"Neutralization of TSLP inhibits airway remodeling in a murine model of allergic asthma induced by chronic exposure to house dust mite","volume":"8","author":"Chen","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jaci.2014.12.1936_bib21","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jaci.2012.08.002","article-title":"IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization","volume":"131","author":"Chu","year":"2013","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2014.12.1936_bib22","doi-asserted-by":"crossref","first-page":"2102","DOI":"10.1056\/NEJMoa1402895","article-title":"Effects of an anti-TSLP antibody on allergen-induced asthmatic responses","volume":"370","author":"Gauvreau","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2014.12.1936_bib23","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.jaci.2010.04.028","article-title":"Expression of IL-4 receptor alpha on smooth muscle cells is not necessary for development of experimental allergic asthma","volume":"126","author":"Kirstein","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2014.12.1936_bib24","doi-asserted-by":"crossref","first-page":"3078","DOI":"10.1002\/eji.200939302","article-title":"Thymic stromal lymphopoietin is a critical mediator of IL-13-driven allergic inflammation","volume":"39","author":"Miyata","year":"2009","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jaci.2014.12.1936_bib25","doi-asserted-by":"crossref","first-page":"7232","DOI":"10.4049\/jimmunol.1100504","article-title":"IL-13 induces skin fibrosis in atopic dermatitis by thymic stromal lymphopoietin","volume":"186","author":"Oh","year":"2011","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2014.12.1936_bib26","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/srep00023","article-title":"The role of TSLP in IL-13-induced atopic march","volume":"1","author":"Zhu","year":"2011","journal-title":"Sci Rep"},{"key":"10.1016\/j.jaci.2014.12.1936_bib27","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/nrd3930","article-title":"Clinical targeting of the TNF and TNFR superfamilies","volume":"12","author":"Croft","year":"2013","journal-title":"Nat Rev Drug Discov"},{"key":"10.1016\/j.jaci.2014.12.1936_bib28","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.jaci.2010.02.008","article-title":"Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes","volume":"125","author":"Hastie","year":"2009","journal-title":"J Allergy Clin Immunol"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674915000172?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674915000172?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T08:53:25Z","timestamp":1758790405000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674915000172"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["S0091674915000172"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2014.12.1936","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tumor necrosis factor superfamily 14 (LIGHT) controls thymic stromal lymphopoietin to drive pulmonary fibrosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2014.12.1936","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}