{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T01:34:40Z","timestamp":1791423280606,"version":"4.3.3"},"reference-count":65,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.jaci.2017.10.030","type":"journal-article","created":{"date-parts":[[2017,11,16]],"date-time":"2017-11-16T19:45:15Z","timestamp":1510861515000},"page":"246-257","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":63,"title":["Type I IFN\u2013related NETosis in ataxia telangiectasia and Artemis deficiency"],"prefix":"10.1016","volume":"142","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2873-8034","authenticated-orcid":false,"given":"Ersin","family":"Gul","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esra Hazar","family":"Sayar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilgi","family":"Gungor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fehime Kara","family":"Eroglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naz","family":"Surucu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sevgi","family":"Keles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8860-6132","authenticated-orcid":false,"given":"Sukru Nail","family":"Guner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siddika","family":"Findik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esin","family":"Alpdundar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ihsan Cihan","family":"Ayanoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basak","family":"Kayaoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Busra Nur","family":"Geckin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatice Asena","family":"Sanli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamer","family":"Kahraman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cengiz","family":"Yakicier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meltem","family":"Muftuoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berna","family":"Oguz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deniz Nazire","family":"Cagdas Ayvaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ihsan","family":"Gursel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seza","family":"Ozen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismail","family":"Reisli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0044-9054","authenticated-orcid":false,"given":"Mayda","family":"Gursel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2017.10.030_bib1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1038\/nri3850","article-title":"Aicardi-Gouti\u00e8res syndrome and the type I interferonopathies","volume":"15","author":"Crow","year":"2015","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jaci.2017.10.030_bib2","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s00281-015-0500-x","article-title":"Type I interferonopathies\u2014an expanding disease spectrum of immunodysregulation","volume":"37","author":"Lee-Kirsch","year":"2015","journal-title":"Semin Immunopathol"},{"key":"10.1016\/j.jaci.2017.10.030_bib3","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1146\/annurev-immunol-032414-112227","article-title":"Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling","volume":"33","author":"de Jesus","year":"2015","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.jaci.2017.10.030_bib4","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1084\/jem.20161596","article-title":"Type I interferon-mediated monogenic autoinflammation: the type I interferonopathies, a conceptual overview","volume":"213","author":"Rodero","year":"2016","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2017.10.030_bib5","doi-asserted-by":"crossref","first-page":"18490","DOI":"10.1073\/pnas.0809242105","article-title":"An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer","volume":"105","author":"Weichselbaum","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jaci.2017.10.030_bib6","doi-asserted-by":"crossref","first-page":"4249","DOI":"10.1158\/1078-0432.CCR-12-3666","article-title":"Cyclophosphamide induces a type I interferon-associated sterile inflammatory response signature in cancer patients\u2019 blood cells: implications for cancer chemoimmunotherapy","volume":"19","author":"Moschella","year":"2013","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.jaci.2017.10.030_bib7","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.celrep.2015.03.069","article-title":"DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function","volume":"11","author":"Yu","year":"2015","journal-title":"Cell Rep"},{"key":"10.1016\/j.jaci.2017.10.030_bib8","doi-asserted-by":"crossref","first-page":"5336","DOI":"10.4049\/jimmunol.1100040","article-title":"The DNA damage response induces IFN","volume":"187","author":"Brzostek-Racine","year":"2011","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2017.10.030_bib9","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1158\/0008-5472.CAN-13-1703","article-title":"RAE1 ligands for the NKG2D receptor are regulated by STING-dependent DNA sensor pathways in lymphoma","volume":"74","author":"Lam","year":"2014","journal-title":"Cancer Res"},{"key":"10.1016\/j.jaci.2017.10.030_bib10","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.celrep.2015.03.041","article-title":"Genome-derived cytosolic DNA mediates type I interferon-dependent rejection of B cell lymphoma cells","volume":"11","author":"Shen","year":"2015","journal-title":"Cell Rep"},{"key":"10.1016\/j.jaci.2017.10.030_bib11","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.immuni.2015.01.012","article-title":"DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity","volume":"42","author":"H\u00e4rtlova","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.jaci.2017.10.030_bib12","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1146\/annurev.immunol.15.1.177","article-title":"The genetic defect in ataxia telangiectasia","volume":"15","author":"Lavin","year":"1997","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.jaci.2017.10.030_bib13","doi-asserted-by":"crossref","first-page":"2842","DOI":"10.1182\/blood-2015-05-645424","article-title":"Neutrophil oxidative burst activates ATM to regulate cytokine production and apoptosis","volume":"126","author":"Harbort","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.jaci.2017.10.030_bib14","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1159\/000246117","article-title":"Cutaneous granulomas as a presenting sign in ataxia-telangiectasia","volume":"194","author":"Drolet","year":"1997","journal-title":"Dermatology"},{"key":"10.1016\/j.jaci.2017.10.030_bib15","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1159\/000330335","article-title":"Cutaneous granulomas in ataxia telangiectasia and other primary immunodeficiencies: reflection of inappropriate immune regulation?","volume":"223","author":"Chiam","year":"2011","journal-title":"Dermatology"},{"key":"10.1016\/j.jaci.2017.10.030_bib16","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/S0022-3476(71)80353-0","article-title":"Autoimmune phenomena in ataxia telangiectasia","volume":"78","author":"Ammann","year":"1971","journal-title":"J Pediatr"},{"key":"10.1016\/j.jaci.2017.10.030_bib17","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3109\/08916930008994084","article-title":"Is there an association between autoimmune hemolytic anemia and ataxia-telangiectasia?","volume":"32","author":"Kutukculer","year":"2000","journal-title":"Autoimmunity"},{"key":"10.1016\/j.jaci.2017.10.030_bib18","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.jpeds.2009.12.007","article-title":"Elevated serum IL-8 levels in ataxia telangiectasia","volume":"156","author":"McGrath-Morrow","year":"2010","journal-title":"J Pediatr"},{"key":"10.1016\/j.jaci.2017.10.030_bib19","doi-asserted-by":"crossref","first-page":"6986","DOI":"10.1093\/nar\/gkr331","article-title":"Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair","volume":"39","author":"Woodbine","year":"2011","journal-title":"Nucl Acids Res"},{"key":"10.1016\/j.jaci.2017.10.030_bib20","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.0105-2896.2004.00169.x","article-title":"Artemis sheds new light on V(D)J recombination","volume":"200","author":"Le Deist","year":"2004","journal-title":"Immunol Rev"},{"key":"10.1016\/j.jaci.2017.10.030_bib21","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.jpeds.2003.12.046","article-title":"Immunodeficiency and infections in ataxia-telangiectasia","volume":"144","author":"Nowak-Wegrzyn","year":"2004","journal-title":"J Pediatr"},{"key":"10.1016\/j.jaci.2017.10.030_bib22","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/ppul.22817","article-title":"Infections of the respiratory system in patients with ataxia-telangiectasia","volume":"49","author":"Schroeder","year":"2013","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jaci.2017.10.030_bib23","doi-asserted-by":"crossref","first-page":"7361","DOI":"10.1093\/hmg\/ddv437","article-title":"DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency","volume":"24","author":"Volk","year":"2015","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jaci.2017.10.030_bib24","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.jaci.2015.03.005","article-title":"Functional analysis of naturally occurring DCLRE1C mutations and correlation with the clinical phenotype of ARTEMIS deficiency","volume":"136","author":"Felgentreff","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2017.10.030_bib25","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.clim.2013.08.006","article-title":"The many faces of Artemis-deficient combined immunodeficiency\u2014two patients with DCLRE1C mutations and a systematic literature review of genotype-phenotype correlation","volume":"149","author":"Lee","year":"2013","journal-title":"Clin Immunol"},{"key":"10.1016\/j.jaci.2017.10.030_bib26","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1172\/JCI16774","article-title":"Partial T and B lymphocyte immunodeficiency and predisposition to lymphoma in patients with hypomorphic mutations in Artemis","volume":"111","author":"Moshous","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2017.10.030_bib27","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1056\/NEJMoa1312625","article-title":"Activated\u00a0STING in a vascular and pulmonary syndrome N","volume":"371","author":"Liu","year":"2014","journal-title":"Engl J Med"},{"key":"10.1016\/j.jaci.2017.10.030_bib28","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/gene.2011.16","article-title":"Artemis splice defects cause atypical SCID and can be restored in\u00a0vitro by an antisense oligonucleotide","volume":"12","author":"Ijspeert","year":"2011","journal-title":"Genes Immun"},{"key":"10.1016\/j.jaci.2017.10.030_bib29","doi-asserted-by":"crossref","first-page":"4179","DOI":"10.1182\/blood-2004-12-4861","article-title":"Omenn syndrome due to ARTEMIS mutations","volume":"105","author":"Ege","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.jaci.2017.10.030_bib30","doi-asserted-by":"crossref","first-page":"73ra20","DOI":"10.1126\/scitranslmed.3001201","article-title":"Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus","volume":"3","author":"Garcia-Romo","year":"2011","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jaci.2017.10.030_bib31","doi-asserted-by":"crossref","first-page":"538","DOI":"10.4049\/jimmunol.1100450","article-title":"Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus","volume":"187","author":"Villanueva","year":"2011","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2017.10.030_bib32","doi-asserted-by":"crossref","first-page":"3284","DOI":"10.4049\/jimmunol.0902199","article-title":"A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs","volume":"184","author":"Denny","year":"2010","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2017.10.030_bib33","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1136\/annrheumdis-2013-204837","article-title":"Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2","volume":"74","author":"Carmona-Rivera","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jaci.2017.10.030_bib34","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1097\/BOR.0000000000000197","article-title":"The role of neutrophils in the pathogenesis of systemic lupus erythematosus","volume":"27","author":"Smith","year":"2015","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.jaci.2017.10.030_bib35","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1002\/art.39818","article-title":"Tofacitinib ameliorates murine lupus and its associated vascular dysfunction","volume":"69","author":"Furumoto","year":"2017","journal-title":"Arthritis Rheumatol"},{"key":"10.1016\/j.jaci.2017.10.030_bib36","doi-asserted-by":"crossref","first-page":"2334","DOI":"10.1096\/fj.09-147991","article-title":"Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane","volume":"24","author":"Aaman","year":"2010","journal-title":"FASEB J"},{"key":"10.1016\/j.jaci.2017.10.030_bib37","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1097\/BOR.0000000000000087","article-title":"Advances in understanding the role of type I interferons in systemic lupus erythematosus","volume":"26","author":"Crow","year":"2014","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.jaci.2017.10.030_bib38","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/nm.4027","article-title":"Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease","volume":"22","author":"Lood","year":"2016","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2017.10.030_bib39","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/s00281-013-0375-7","article-title":"Low-density granulocytes: a distinct class of neutrophils in systemic autoimmunity","volume":"35","author":"Carmona-Rivera","year":"2013","journal-title":"Semin Immunopathol"},{"key":"10.1016\/j.jaci.2017.10.030_bib40","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1126\/science.1092385","article-title":"Neutrophil extracellular traps kill bacteria","volume":"303","author":"Brinkmann","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.jaci.2017.10.030_bib41","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.redox.2016.12.030","article-title":"Oxidative stress, mitochondrial abnormalities and antioxidant defense in Ataxia-telangiectasia, Bloom syndrome and Nijmegen breakage syndrome","volume":"11","author":"Maciejczyk","year":"2016","journal-title":"Redox Biol"},{"key":"10.1016\/j.jaci.2017.10.030_bib42","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/1546-0096-12-44","article-title":"Mutations in CECR1 associated with a neutrophil signature in peripheral blood","volume":"12","author":"Belot","year":"2014","journal-title":"Pediatr Rheumatol Online J"},{"key":"10.1016\/j.jaci.2017.10.030_bib43","doi-asserted-by":"crossref","first-page":"e45427","DOI":"10.1371\/journal.pone.0045427","article-title":"Autophagy mediates the delivery of thrombogenic tissue factor to neutrophil extracellular traps in human sepsis","volume":"7","author":"Kambas","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jaci.2017.10.030_bib44","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3389\/fimmu.2012.00385","article-title":"The emerging role of neutrophils in thrombosis\u2014the journey of TF through NETs","volume":"3","author":"Kambas","year":"2012","journal-title":"Front Immunol"},{"key":"10.1016\/j.jaci.2017.10.030_bib45","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1136\/annrheumdis-2013-203430","article-title":"Tissue factor expression in neutrophil extracellular traps and neutrophil derived microparticles in antineutrophil cytoplasmic antibody associated vasculitis may promote thromboinflammation and the thrombophilic state associated with the disease","volume":"73","author":"Kambas","year":"2014","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jaci.2017.10.030_bib46","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1160\/TH12-06-0425","article-title":"Neutrophils, neutrophil extracellular traps and interleukin-17 associate with the organisation of thrombi in acute myocardial infarction","volume":"109","author":"de Boer","year":"2013","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jaci.2017.10.030_bib47","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1093\/eurheartj\/ehv007","article-title":"Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction","volume":"36","author":"Stakos","year":"2015","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jaci.2017.10.030_bib48","doi-asserted-by":"crossref","first-page":"9813","DOI":"10.1073\/pnas.0909927107","article-title":"Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis","volume":"107","author":"Hakkim","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jaci.2017.10.030_bib49","doi-asserted-by":"crossref","first-page":"73ra19","DOI":"10.1126\/scitranslmed.3001180","article-title":"Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus","volume":"3","author":"Lande","year":"2011","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jaci.2017.10.030_bib50","doi-asserted-by":"crossref","first-page":"4895","DOI":"10.4049\/jimmunol.1302005","article-title":"Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease","volume":"191","author":"Kahlenberg","year":"2013","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2017.10.030_bib51","doi-asserted-by":"crossref","first-page":"3522","DOI":"10.4049\/jimmunol.1102404","article-title":"Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease","volume":"188","author":"Leffler","year":"2012","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2017.10.030_bib52","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1038\/ki.2015.259","article-title":"What is myeloperoxidase doing in ANCA-associated glomerulonephritis?","volume":"88","author":"Couser","year":"2015","journal-title":"Kidney Int"},{"key":"10.1016\/j.jaci.2017.10.030_bib53","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1093\/rheumatology\/kev217","article-title":"Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission","volume":"54","author":"S\u00f6derberg","year":"2015","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.jaci.2017.10.030_bib54","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1136\/annrheumdis-2014-205958","article-title":"Neutrophil extracellular traps regulate IL-1\u03b2-mediated inflammation in familial Mediterranean fever","volume":"75","author":"Apostolidou","year":"2016","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jaci.2017.10.030_bib55","doi-asserted-by":"crossref","first-page":"e29318","DOI":"10.1371\/journal.pone.0029318","article-title":"Neutrophil extracellular trap formation is associated with IL-1\u03b2 and autophagy-related signaling in gout","volume":"6","author":"Mitroulis","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jaci.2017.10.030_bib56","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1097\/MIB.0000000000000460","article-title":"Neutrophil extracellular traps in ulcerative colitis: a proteome analysis of intestinal biopsies","volume":"21","author":"Bennike","year":"2015","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.jaci.2017.10.030_bib57","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1160\/TH15-09-0710","article-title":"Phosphotidylserine exposure and neutrophil extracellular traps enhance procoagulant activity in patients with inflammatory bowel disease","volume":"115","author":"He","year":"2016","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jaci.2017.10.030_bib58","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s00592-014-0676-x","article-title":"NETosis is induced by high glucose and associated with type 2 diabetes","volume":"52","author":"Menegazzo","year":"2015","journal-title":"Acta Diabetol"},{"key":"10.1016\/j.jaci.2017.10.030_bib59","doi-asserted-by":"crossref","first-page":"4239","DOI":"10.2337\/db14-0480","article-title":"Increased neutrophil elastase and proteinase 3 and augmented NETosis are closely associated with \u03b2-cell autoimmunity in patients with type 1 diabetes","volume":"63","author":"Wang","year":"2014","journal-title":"Diabetes"},{"key":"10.1016\/j.jaci.2017.10.030_bib60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fimmu.2013.00001","article-title":"NET balancing: a problem in inflammatory lung diseases","volume":"4","author":"Cheng","year":"2013","journal-title":"Front Immunol"},{"key":"10.1016\/j.jaci.2017.10.030_bib61","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s12931-015-0221-7","article-title":"Neutrophil extracellular trap (NET) formation characterises stable and exacerbated COPD and correlates with airflow limitation","volume":"16","author":"Grabcanovic-Musija","year":"2015","journal-title":"Respir Res"},{"key":"10.1016\/j.jaci.2017.10.030_bib62","doi-asserted-by":"crossref","first-page":"408935","DOI":"10.1155\/2015\/408935","article-title":"Free DNA in cystic fibrosis airway fluids correlates with airflow obstruction","volume":"2015","author":"Marcos","year":"2015","journal-title":"Mediators Inflamm"},{"key":"10.1016\/j.jaci.2017.10.030_bib63","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1159\/000363242","article-title":"Cystic fibrosis sputum DNA has NETosis characteristics and neutrophil extracellular trap release is regulated by macrophage migration-inhibitory factor","volume":"6","author":"Dwyer","year":"2014","journal-title":"J Innate Immun"},{"key":"10.1016\/j.jaci.2017.10.030_bib64","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1002\/path.4359","article-title":"Neutrophil extracellular traps promote differentiation and function of fibroblasts","volume":"233","author":"Chrysanthopoulou","year":"2014","journal-title":"J Pathol"},{"key":"10.1016\/j.jaci.2017.10.030_bib65","doi-asserted-by":"crossref","first-page":"13076","DOI":"10.1073\/pnas.1200419109","article-title":"Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis","volume":"109","author":"Demers","year":"2012","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674917317621?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674917317621?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T09:10:55Z","timestamp":1758791455000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674917317621"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":65,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["S0091674917317621"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2017.10.030","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Type I IFN\u2013related NETosis in ataxia telangiectasia and Artemis deficiency","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2017.10.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}