{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T01:56:06Z","timestamp":1782266166729,"version":"3.54.5"},"reference-count":153,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100006492","name":"Division of Intramural Research of the National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.jaci.2018.10.063","type":"journal-article","created":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T13:00:00Z","timestamp":1544101200000},"page":"880-893","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":66,"title":["Adverse reactions to drugs and biologics in patients with clonal mast cell disorders: A\u00a0Work Group Report of the Mast Cells Disorder Committee, American Academy of Allergy, Asthma &amp; Immunology"],"prefix":"10.1016","volume":"143","author":[{"given":"Melody C.","family":"Carter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dean D.","family":"Metcalfe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Almudena","family":"Matito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Escribano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph H.","family":"Butterfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence B.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizia","family":"Bonadonna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Zanotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Triggiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Castells","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knut","family":"Brockow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2018.10.063_bib1","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1365-2362.2007.01807.x","article-title":"Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria","volume":"37","author":"Valent","year":"2007","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.jaci.2018.10.063_bib2","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.iac.2014.01.003","article-title":"Epidemiology, prognosis, and risk factors in mastocytosis","volume":"34","author":"Brockow","year":"2014","journal-title":"Immunol Allergy Clin North Am"},{"key":"10.1016\/j.jaci.2018.10.063_bib3","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1159\/000237541","article-title":"c-kit mutation in a population of patients with mastocytosis","volume":"113","author":"Nagata","year":"1997","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib4","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1182\/blood-2016-09-731893","article-title":"Mastocytosis 2016: updated WHO classification and novel emerging treatment concepts","volume":"129","author":"Valent","year":"2017","journal-title":"Blood"},{"key":"10.1016\/j.jaci.2018.10.063_bib5","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.jaci.2003.12.591","article-title":"Revised nomenclature for allergy for global use: report of the Nomenclature Review Committee of the World Allergy Organization, October 2003","volume":"113","author":"Johansson","year":"2004","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib6","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.jaci.2005.12.1303","article-title":"Second symposium on the definition and management of anaphylaxis: summary report\u2014Second National Institute of Allergy and Infectious Disease\/Food Allergy and Anaphylaxis Network symposium","volume":"117","author":"Sampson","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib7","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/j.1398-9995.2007.01569.x","article-title":"Anaphylaxis in patients with mastocytosis: a study on history, clinical features and risk factors in 120 patients","volume":"63","author":"Brockow","year":"2008","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib8","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1002\/ajh.24490","article-title":"Risk of solid cancer, cardiovascular disease, anaphylaxis, osteoporosis and fractures in patients with systemic mastocytosis: a nationwide population-based study","volume":"91","author":"Broesby-Olsen","year":"2016","journal-title":"Am J Hematol"},{"key":"10.1016\/j.jaci.2018.10.063_bib9","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1111\/j.1365-2222.2007.02804.x","article-title":"Prevalence of allergy and anaphylactic symptoms in 210 adult and pediatric patients with mastocytosis in Spain: a study of the Spanish network on mastocytosis (REMA)","volume":"37","author":"Gonzalez de Olano","year":"2007","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib10","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1111\/j.1398-9995.2012.02812.x","article-title":"Increased serum baseline tryptase levels and extensive skin involvement are predictors for the severity of mast cell activation episodes in children with mastocytosis","volume":"67","author":"Alvarez-Twose","year":"2012","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib11","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1111\/all.12013","article-title":"Extensive blistering is a predictor for severe complications in children with mastocytosis","volume":"67","author":"Brockow","year":"2012","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib12","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/cea.12225","article-title":"High prevalence of anaphylaxis in patients with systemic mastocytosis\u2014a single-centre experience","volume":"44","author":"Gulen","year":"2014","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib13","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.jaci.2013.06.020","article-title":"Nonaggressive systemic mastocytosis (SM) without skin lesions associated with insect-induced anaphylaxis shows unique features versus other indolent SM","volume":"133","author":"Alvarez-Twose","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib14","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1182\/blood-2006-06-028100","article-title":"Demonstration of an aberrant mast-cell population with clonal markers in a subset of patients with \u201cidiopathic\u201d anaphylaxis","volume":"110","author":"Akin","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.jaci.2018.10.063_bib15","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1159\/000096442","article-title":"Diagnostic and subdiagnostic accumulation of mast cells in the bone marrow of patients with anaphylaxis: monoclonal mast cell activation syndrome","volume":"142","author":"Sonneck","year":"2007","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib16","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1097\/ACI.0b013e328355b7cb","article-title":"Drug allergy in mast cell disease","volume":"12","author":"Brockow","year":"2012","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib17","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0140-6736(00)03647-3","article-title":"Constitutively raised serum concentrations of mast-cell tryptase and severe anaphylactic reactions to Hymenoptera stings","volume":"357","author":"Ludolph-Hauser","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.jaci.2018.10.063_bib18","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1213\/ane.0b013e31817e6d7c","article-title":"Pediatric mastocytosis: routine anesthetic management for a complex disease","volume":"107","author":"Carter","year":"2008","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jaci.2018.10.063_bib19","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1097\/ALN.0000000000000031","article-title":"Perioperative management of patients with mastocytosis","volume":"120","author":"Dewachter","year":"2014","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jaci.2018.10.063_bib20","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1007\/s00277-002-0575-z","article-title":"Mastocytosis: current concepts in diagnosis and treatment","volume":"81","author":"Escribano","year":"2002","journal-title":"Ann Hematol"},{"key":"10.1016\/j.jaci.2018.10.063_bib21","first-page":"54","article-title":"Activation of human mast cells and basophils by general anaesthetic drugs","volume":"30","author":"Marone","year":"1992","journal-title":"Monogr Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib22","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1093\/bja\/67.6.751","article-title":"General anaesthetics induce only histamine release selectively from human mast cells","volume":"67","author":"Stellato","year":"1991","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jaci.2018.10.063_bib23","first-page":"108","article-title":"Mast cells and basophils in adverse reactions to drugs used during general anesthesia","volume":"62","author":"Stellato","year":"1995","journal-title":"Chem Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib24","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1177\/0310057X1304100120","article-title":"Systemic mastocytosis presenting as intraoperative anaphylaxis with atypical features: a report of two cases","volume":"41","author":"Bridgman","year":"2013","journal-title":"Anaesth Intensive Care"},{"key":"10.1016\/j.jaci.2018.10.063_bib25","first-page":"77","volume":"41","author":"Brodier","year":"1993","journal-title":"Cah Anesthesiol"},{"key":"10.1016\/j.jaci.2018.10.063_bib26","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1213\/00000539-198009000-00015","article-title":"General anesthesia in a child with urticaria pigmentosa","volume":"59","author":"Coleman","year":"1980","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jaci.2018.10.063_bib27","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1093\/bja\/65.6.833","article-title":"Massive histamine release in a patient with systemic mastocytosis","volume":"65","author":"Desborough","year":"1990","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jaci.2018.10.063_bib28","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/0952-8180(90)90063-9","article-title":"Urticaria pigmentosa: an anesthetic challenge","volume":"2","author":"Greenblatt","year":"1990","journal-title":"J Clin Anesth"},{"key":"10.1016\/j.jaci.2018.10.063_bib29","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1213\/00000539-198704000-00011","article-title":"Sudden intraoperative hypotension in a patient with asymptomatic urticaria pigmentosa","volume":"66","author":"Hosking","year":"1987","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jaci.2018.10.063_bib30","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1097\/00000658-198305000-00002","article-title":"Hazards in operative management of patients with systemic mastocytosis","volume":"197","author":"Scott","year":"1983","journal-title":"Ann Surg"},{"key":"10.1016\/j.jaci.2018.10.063_bib31","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1111\/j.1365-2044.1987.tb04112.x","article-title":"Histamine levels and cardiovascular responses during splenectomy and splenorenal shunt formation in a patient with systemic mastocytosis","volume":"42","author":"Smith","year":"1987","journal-title":"Anaesthesia"},{"key":"10.1016\/j.jaci.2018.10.063_bib32","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/S0750-7658(01)00536-6","volume":"20","author":"Tirel","year":"2001","journal-title":"Ann Fr Anesth Reanim"},{"key":"10.1016\/j.jaci.2018.10.063_bib33","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1046\/j.1365-2044.1998.00536.x","article-title":"Systemic mastocytosis presenting as profound cardiovascular collapse during anaesthesia","volume":"53","author":"Vaughan","year":"1998","journal-title":"Anaesthesia"},{"key":"10.1016\/j.jaci.2018.10.063_bib34","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1159\/000436969","article-title":"Management of anesthesia in adult and pediatric mastocytosis: a study of the Spanish Network on Mastocytosis (REMA) based on 726 anesthetic procedures","volume":"167","author":"Matito","year":"2015","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib35","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1460-9592.2008.02904.x","article-title":"Anesthesia in children with mastocytosis\u2014a case based review","volume":"19","author":"Ahmad","year":"2009","journal-title":"Paediatr Anaesth"},{"key":"10.1016\/j.jaci.2018.10.063_bib36","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0750-7658(01)00440-3","volume":"20","author":"Auvray","year":"2001","journal-title":"Ann Fr Anesth Reanim"},{"key":"10.1016\/j.jaci.2018.10.063_bib37","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1213\/00000539-199802000-00044","article-title":"Anesthesia in a patient with malignant systemic mastocytosis using a total intravenous anesthetic technique","volume":"86","author":"Borgeat","year":"1998","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jaci.2018.10.063_bib38","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.jaci.2011.03.003","article-title":"Groupe d'Etudes des Reactions Anaphylactoides P. Anaphylaxis during anesthesia in France: an 8-year national survey","volume":"128","author":"Mertes","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib39","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1097\/00000542-199106000-00016","article-title":"Heterogeneity of human mast cells and basophils in response to muscle relaxants","volume":"74","author":"Stellato","year":"1991","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jaci.2018.10.063_bib40","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1097\/00000542-200109000-00019","article-title":"Different patterns of mast cell activation by muscle relaxants in human skin","volume":"95","author":"Koppert","year":"2001","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jaci.2018.10.063_bib41","first-page":"623","article-title":"The lack of histamine release with cisatracurium: a double-blind comparison with vecuronium","volume":"84","author":"Doenicke","year":"1997","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jaci.2018.10.063_bib42","first-page":"868","article-title":"Hypersensitivity reactions during anesthesia. Results from the ninth French survey (2005-2007)","volume":"78","author":"Dong","year":"2012","journal-title":"Minerva Anestesiol"},{"key":"10.1016\/j.jaci.2018.10.063_bib43","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/s00540-015-2105-x","article-title":"Sugammadex and rocuronium-induced anaphylaxis","volume":"30","author":"Takazawa","year":"2016","journal-title":"J Anesth"},{"key":"10.1016\/j.jaci.2018.10.063_bib44","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1007\/BF03003441","article-title":"Neuroendocrine and metabolic effects of general anaesthesia during spontaneous breathing, controlled breathing, milk hypoxia, and mild hypercarbia","volume":"13","author":"Dobkin","year":"1966","journal-title":"Can Anaesth Soc J"},{"key":"10.1016\/j.jaci.2018.10.063_bib45","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.3892\/mmr.2015.3527","article-title":"Sevoflurane ameliorates intestinal ischemia-reperfusion-induced lung injury by inhibiting the synergistic action between mast cell activation and oxidative stress","volume":"12","author":"Luo","year":"2015","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.jaci.2018.10.063_bib46","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1177\/0310057X1204000204","article-title":"Histamine-releasing and allergenic properties of opioid analgesic drugs: resolving the two","volume":"40","author":"Baldo","year":"2012","journal-title":"Anaesth Intensive Care"},{"key":"10.1016\/j.jaci.2018.10.063_bib47","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/S0750-7658(05)81020-2","article-title":"Mechanisms of activation of human mast cells and basophils by general anesthetic drugs","volume":"12","author":"Marone","year":"1993","journal-title":"Ann Fr Anesth Reanim"},{"key":"10.1016\/j.jaci.2018.10.063_bib48","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1097\/00000542-199211000-00016","article-title":"Human basophil\/mast cell releasability. IX. Heterogeneity of the effects of opioids on mediator release","volume":"77","author":"Stellato","year":"1992","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jaci.2018.10.063_bib49","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1213\/01.ANE.0000097168.32472.0D","article-title":"Opioid-induced mast cell activation and vascular responses is not mediated by mu-opioid receptors: an in\u00a0vivo microdialysis study in human skin","volume":"98","author":"Blunk","year":"2004","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jaci.2018.10.063_bib50","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/00000542-198405000-00020","article-title":"Hemodynamics and histamine release during induction with sufentanil or fentanyl","volume":"60","author":"Rosow","year":"1984","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jaci.2018.10.063_bib51","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1111\/j.1365-2249.2008.03636.x","article-title":"Lidocaine down-regulates nuclear factor-kappaB signalling and inhibits cytokine production and T cell proliferation","volume":"152","author":"Lahat","year":"2008","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib52","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1111\/j.1399-6576.1996.tb05577.x","article-title":"Effect of lidocaine on histamine release and Ca2+ mobilization from mast cells and basophils","volume":"40","author":"Yanagi","year":"1996","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.jaci.2018.10.063_bib53","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.lpm.2016.05.011","article-title":"Allergy to local anesthetics: reality or myth?","volume":"45","author":"Malinovsky","year":"2016","journal-title":"Presse Med"},{"key":"10.1016\/j.jaci.2018.10.063_bib54","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1093\/bja\/aes162","article-title":"IgE-mediated allergy to local anaesthetics: separating fact from perception: a UK perspective","volume":"108","author":"Bhole","year":"2012","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jaci.2018.10.063_bib55","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.annfar.2008.09.022","volume":"28","author":"Dewachter","year":"2009","journal-title":"Ann Fr Anesth Reanim"},{"key":"10.1016\/j.jaci.2018.10.063_bib56","article-title":"Some untoward effects of acetyl salicylic acid","volume":"99","author":"Lamson","year":"1932","journal-title":"JAMA"},{"key":"10.1016\/j.jaci.2018.10.063_bib57","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1007\/s00540-013-1563-2","article-title":"Anesthetic considerations in pediatric mastocytosis: a review","volume":"27","author":"Klein","year":"2013","journal-title":"J Anesth"},{"key":"10.1016\/j.jaci.2018.10.063_bib58","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1159\/000328760","article-title":"Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal","volume":"157","author":"Valent","year":"2012","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib59","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/S0025-7125(16)31397-9","article-title":"Treatment of urticaria","volume":"66","author":"Guin","year":"1982","journal-title":"Med Clin North Am"},{"key":"10.1016\/j.jaci.2018.10.063_bib60","first-page":"101","article-title":"Death following ingestion of 5 grains of acetyl salicylic acid","author":"Dysart","year":"1933","journal-title":"JAMA"},{"key":"10.1016\/j.jaci.2018.10.063_bib61","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/0091-6749(83)90439-6","article-title":"Aspirin-sensitive rhinosinusitis\/asthma: spectrum of adverse reactions to aspirin","volume":"71","author":"Pleskow","year":"1983","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib62","doi-asserted-by":"crossref","first-page":"975","DOI":"10.7326\/0003-4819-68-5-975","article-title":"Intolerance to aspirin. Clinical studies and consideration of its pathogenesis","volume":"68","author":"Samter","year":"1968","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jaci.2018.10.063_bib63","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1067\/mai.2003.1387","article-title":"A controlled study of 9alpha,11beta-PGF2 (a prostaglandin D2 metabolite) in plasma and urine of patients with bronchial asthma and healthy controls after aspirin challenge","volume":"111","author":"Bochenek","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib64","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/0091-6749(91)90238-J","article-title":"Tryptase and histamine release during aspirin-induced respiratory reactions","volume":"88","author":"Bosso","year":"1991","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib65","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/0091-6749(83)90440-2","article-title":"Aspirin-sensitive rhinosinusitis: the clinical syndrome and effects of aspirin administration","volume":"71","author":"Lumry","year":"1983","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib66","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1067\/mjd.2003.98","article-title":"Assessment of the extent of cutaneous involvement in children and adults with mastocytosis: relationship to symptomatology, tryptase levels, and bone marrow pathology","volume":"48","author":"Brockow","year":"2003","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaci.2018.10.063_bib67","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1111\/j.1398-9995.1990.tb00945.x","article-title":"Mastocytosis and atopy: a study of 33 patients with urticaria pigmentosa","volume":"45","author":"Muller","year":"1990","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib68","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.jaci.2008.11.018","article-title":"Clonal mast cell disorders in patients with systemic reactions to Hymenoptera stings and increased serum tryptase levels","volume":"123","author":"Bonadonna","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib69","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/j.1365-2222.2005.02213.x","article-title":"Exercise and aspirin increase levels of circulating gliadin peptides in patients with wheat-dependent exercise-induced anaphylaxis","volume":"35","author":"Matsuo","year":"2005","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib70","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jdermsci.2007.03.004","article-title":"Food-dependent exercise-induced anaphylaxis","volume":"47","author":"Morita","year":"2007","journal-title":"J Dermatol Sci"},{"key":"10.1016\/j.jaci.2018.10.063_bib71","first-page":"230","article-title":"Acetylsalicylic acid dependent anaphylaxis to carrots in a patient with mastocytosis","volume":"9","author":"Pfeffer","year":"2011","journal-title":"J Dtsch Dermatol Ges"},{"key":"10.1016\/j.jaci.2018.10.063_bib72","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1111\/all.12668","article-title":"Urinary 11beta-PGF2alpha and N-methyl histamine correlate with bone marrow biopsy findings in mast cell disorders","volume":"70","author":"Divekar","year":"2015","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib73","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.jaip.2014.06.011","article-title":"Mast cell activation syndrome: improved identification by combined determinations of serum tryptase and 24-hour urine 11beta-prostaglandin2alpha","volume":"2","author":"Ravi","year":"2014","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2018.10.063_bib74","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1056\/NEJM198012113032405","article-title":"Increased production of prostaglandin D2 in patients with systemic mastocytosis","volume":"303","author":"Roberts","year":"1980","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2018.10.063_bib75","first-page":"145","article-title":"Shock syndrome associated with mastocytosis: pharmacologic reversal of the acute episode and therapeutic prevention of recurrent attacks","volume":"8","author":"Roberts","year":"1982","journal-title":"Adv Shock Res"},{"key":"10.1016\/j.jaci.2018.10.063_bib76","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.prostaglandins.2009.01.001","article-title":"Survey of aspirin administration in systemic mastocytosis","volume":"88","author":"Butterfield","year":"2009","journal-title":"Prostaglandins Other Lipid Mediat"},{"key":"10.1016\/j.jaci.2018.10.063_bib77","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0145-2126(01)00039-X","article-title":"Treatment of mastocytosis: pharmacologic basis and current concepts","volume":"25","author":"Marone","year":"2001","journal-title":"Leuk Res"},{"key":"10.1016\/j.jaci.2018.10.063_bib78","first-page":"36","article-title":"Mastocytosis without urticaria pigmentosa: a\u00a0frequently unrecognized cause of recurrent syncope","volume":"95","author":"Roberts","year":"1982","journal-title":"Trans Assoc Am Physicians"},{"key":"10.1016\/j.jaci.2018.10.063_bib79","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1046\/j.1523-1747.1999.00624.x","article-title":"Increased formation of thromboxane in\u00a0vivo in humans with mastocytosis","volume":"113","author":"Morrow","year":"1999","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2018.10.063_bib80","doi-asserted-by":"crossref","first-page":"481","DOI":"10.4065\/70.5.481","article-title":"Aspirin idiosyncrasy in systemic mast cell disease: a new look at mediator release during aspirin desensitization","volume":"70","author":"Butterfield","year":"1995","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.jaci.2018.10.063_bib81","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1159\/000144042","article-title":"Prevention of mast cell activation disorder-associated clinical sequelae of excessive prostaglandin D(2) production","volume":"147","author":"Butterfield","year":"2008","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib82","first-page":"1","article-title":"Systemic mastocytosis: management of an unusual case with histamine (H1 and H2) antagonists and cyclooxygenase inhibition","volume":"10","author":"Crawhall","year":"1987","journal-title":"Clin Invest Med"},{"key":"10.1016\/j.jaci.2018.10.063_bib83","first-page":"18","article-title":"The flush syndrome: an expression of systemic mastocytosis with increased prostaglandin D2 production","volume":"26","author":"Kootte","year":"1983","journal-title":"Neth J Med"},{"key":"10.1016\/j.jaci.2018.10.063_bib84","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/S0140-6736(89)91516-X","article-title":"Aspirin and systemic mastocytosis","volume":"2","author":"Lorcerie","year":"1989","journal-title":"Lancet"},{"key":"10.1016\/j.jaci.2018.10.063_bib85","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1067\/mai.2000.104571","article-title":"Rapid oral challenge-desensitization for patients with aspirin-related urticaria-angioedema","volume":"105","author":"Wong","year":"2000","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib86","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.jaip.2014.03.014","article-title":"Nonsteroidal anti-inflammatory drugs are major causes of drug-induced anaphylaxis","volume":"2","author":"Aun","year":"2014","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"suppl","key":"10.1016\/j.jaci.2018.10.063_bib87","doi-asserted-by":"crossref","first-page":"S161","DOI":"10.1016\/j.jaci.2009.12.981","volume":"125","author":"Simons","year":"2010","journal-title":"Anaphylaxis. J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib88","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1111\/j.1398-9995.2011.02557.x","article-title":"Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs)\u2014classification, diagnosis and management: review of the EAACI\/ENDA(#) and GA2LEN\/HANNA*","volume":"66","author":"Kowalski","year":"2011","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib89","first-page":"551","article-title":"Prevalence of hypersensitivity reactions to nonsteroidal anti-inflamatory drugs in 212 patients with mastocytosis in Spain","volume":"64","author":"Sanchez-Matas","year":"2009","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib90","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/1710-1492-10-19","article-title":"Non-steroidal anti-inflammatory drug hypersensitivity: association with elevated basal serum tryptase?","volume":"10","author":"Seitz","year":"2014","journal-title":"Allergy Asthma Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib91","first-page":"288","article-title":"Mastocytosis and allergic diseases","volume":"24","author":"Bonadonna","year":"2014","journal-title":"J Investig Allergol Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib92","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1111\/cea.12369","article-title":"The presence of mast cell clonality in patients with unexplained anaphylaxis","volume":"44","author":"Gulen","year":"2014","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib93","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0091-6749(97)70314-2","article-title":"Fatal anaphylaxis after a yellow jacket sting, despite venom immunotherapy, in two patients with mastocytosis","volume":"99","author":"Oude Elberink","year":"1997","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib94","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1097\/01.all.0000235903.10548.63","article-title":"Mastocytosis and Hymenoptera venom allergy","volume":"6","author":"Rueff","year":"2006","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib95","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/j.jaci.2010.02.019","article-title":"Clinical, biological, and molecular characteristics of clonal mast cell disorders presenting with systemic mast cell activation symptoms","volume":"125","author":"Alvarez-Twose","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib96","doi-asserted-by":"crossref","first-page":"482","DOI":"10.3324\/haematol.2010.034553","article-title":"Isolated bone marrow mastocytosis: an underestimated subvariant of indolent systemic mastocytosis","volume":"96","author":"Zanotti","year":"2011","journal-title":"Haematologica"},{"key":"10.1016\/j.jaci.2018.10.063_bib97","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.jaci.2014.11.035","article-title":"Clonal mast cell disorders in patients with severe Hymenoptera venom allergy and normal serum tryptase levels","volume":"136","author":"Zanotti","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib98","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.jaci.2007.10.014","article-title":"Allergen specific immunotherapy is safe and effective in patients with systemic mastocytosis and Hymenoptera allergy","volume":"121","author":"Bonadonna","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib99","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.jaci.2007.11.010","article-title":"Safety and effectiveness of immunotherapy in patients with indolent systemic mastocytosis presenting with Hymenoptera venom anaphylaxis","volume":"121","author":"Gonzalez de Olano","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib100","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.jaip.2013.06.014","article-title":"Venom immunotherapy in patients with clonal mast cell disorders: efficacy, safety, and practical considerations","volume":"1","author":"Bonadonna","year":"2013","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2018.10.063_bib101","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/all.13237","article-title":"Omalizumab prevents anaphylaxis and improves symptoms in systemic mastocytosis: efficacy and safety observations","volume":"73","author":"Broesby-Olsen","year":"2018","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib102","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.jaip.2014.03.009","article-title":"Omalizumab as a desensitizing agent and treatment in mastocytosis: a review of the literature and case report","volume":"2","author":"Sokol","year":"2014","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2018.10.063_bib103","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/all.12850","article-title":"Added sensitivity of component-resolved diagnosis in hymenoptera venom-allergic patients with elevated serum tryptase and\/or mastocytosis","volume":"71","author":"Michel","year":"2016","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib104","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1111\/j.1398-9995.2005.00960.x","article-title":"Prevention and treatment of hymenoptera venom allergy: guidelines for clinical practice","volume":"60","author":"Bonifazi","year":"2005","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib105","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1365-2796.1993.tb00984.x","article-title":"Anaphylactoid shock following Hymenoptera sting as a presenting symptom of systemic mastocytosis","volume":"233","author":"Kors","year":"1993","journal-title":"J Intern Med"},{"key":"10.1016\/j.jaci.2018.10.063_bib106","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.anai.2012.09.014","article-title":"Efficacy of venom immunotherapy given every 3 or 4 months: a prospective comparison with the conventional regimen","volume":"110","author":"Simioni","year":"2013","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib107","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1034\/j.1398-9995.2003.00056_2.x","article-title":"Anaphylaxis during negative penicillin skin prick testing confirmed by elevated serum tryptase","volume":"58","author":"Alonso Diaz de Durana","year":"2003","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib108","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1111\/all.12142","article-title":"Skin test concentrations for systemically administered drugs\u2014an ENDA\/EAACI Drug Allergy Interest Group position paper","volume":"68","author":"Brockow","year":"2013","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib109","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/bjd.14004","article-title":"Clinical features and course of cutaneous mastocytosis in 133 children","volume":"174","author":"Schena","year":"2016","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2018.10.063_bib110","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.iac.2014.01.012","article-title":"Treatment strategies in mastocytosis","volume":"34","author":"Siebenhaar","year":"2014","journal-title":"Immunol Allergy Clin North Am"},{"key":"10.1016\/j.jaci.2018.10.063_bib111","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.anai.2010.08.002","article-title":"Drug allergy: an updated practice parameter","volume":"105","author":"Joint Task Force on Practice Parameters","year":"2010","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib112","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.jaci.2009.09.009","article-title":"Hypersensitivity reactions to mAbs: 105 desensitizations in 23 patients, from evaluation to treatment","volume":"124","author":"Brennan","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib113","doi-asserted-by":"crossref","first-page":"227","DOI":"10.3109\/10428199909145725","article-title":"Immunophenotype of bone marrow mast cells in indolent systemic mast cell disease in adults","volume":"35","author":"Escribano","year":"1999","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.jaci.2018.10.063_bib114","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1016\/j.jaci.2007.03.032","article-title":"Omalizumab for the treatment of unprovoked anaphylaxis in patients with systemic mastocytosis","volume":"119","author":"Carter","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib115","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.jaci.2005.09.036","article-title":"Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis","volume":"117","author":"Casale","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib116","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.jaip.2015.03.015","article-title":"Anaphylaxis after hymenoptera sting: is it venom allergy, a clonal disorder, or both?","volume":"3","author":"Castells","year":"2015","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2018.10.063_bib117","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1111\/j.1398-9995.2007.01604.x","article-title":"High omalizumab dose controls recurrent reactions to venom immunotherapy in indolent systemic mastocytosis","volume":"63","author":"Kontou-Fili","year":"2008","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib118","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1111\/j.1398-9995.2009.02045.x","article-title":"Prolonged high-dose omalizumab is required to control reactions to venom immunotherapy in mastocytosis","volume":"64","author":"Kontou-Fili","year":"2009","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib119","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1111\/j.1398-9995.2009.02259.x","article-title":"Omalizumab is effective in treating systemic mastocytosis in a nonatopic patient","volume":"65","author":"Douglass","year":"2010","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib120","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jaci.2012.02.022","article-title":"Ultrarush versus semirush initiation of insect venom immunotherapy: a randomized controlled trial","volume":"130","author":"Brown","year":"2012","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib121","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/j.1365-2222.2007.02887.x","article-title":"Expansion of circulating Foxp3+)D25bright CD4+ T cells during specific venom immunotherapy","volume":"38","author":"Pereira-Santos","year":"2008","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib122","doi-asserted-by":"crossref","first-page":"540","DOI":"10.3109\/10428190903470869","article-title":"Treatment of aggressive systemic mastocytosis with daclizumab","volume":"51","author":"Quintas-Cardama","year":"2010","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.jaci.2018.10.063_bib123","first-page":"217","volume":"34","author":"Bandmann","year":"1983","journal-title":"Hautarzt"},{"key":"10.1016\/j.jaci.2018.10.063_bib124","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1177\/014107680009300309","article-title":"Unexplained loss of consciousness: systemic mastocytosis","volume":"93","author":"Valabhji","year":"2000","journal-title":"J R Soc Med"},{"key":"10.1016\/j.jaci.2018.10.063_bib125","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1177\/0310057X0903700415","article-title":"Anaphylactoid reaction to intravenous contrast in patient with systemic mastocytosis","volume":"37","author":"Weingarten","year":"2009","journal-title":"Anaesth Intensive Care"},{"key":"10.1016\/j.jaci.2018.10.063_bib126","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/j.1398-9995.2008.01832.x","article-title":"Skin testing in patients with hypersensitivity reactions to iodinated contrast media\u2014a European multicenter study","volume":"64","author":"Brockow","year":"2009","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib127","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1111\/j.1398-9995.2005.00745.x","article-title":"Management of hypersensitivity reactions to iodinated contrast media","volume":"60","author":"Brockow","year":"2005","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib128","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1111\/all.12617","article-title":"Drug hypersensitivity in clonal mast cell disorders: ENDA\/EAACI position paper","volume":"70","author":"Bonadonna","year":"2015","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib129","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1111\/j.1365-2222.2010.03493.x","article-title":"Clinical value of negative skin tests to iodinated contrast media","volume":"40","author":"Caimmi","year":"2010","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib130","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1136\/bmj.38905.634132.AE","article-title":"Pharmacological prevention of serious anaphylactic reactions due to iodinated contrast media: systematic review","volume":"333","author":"Tramer","year":"2006","journal-title":"BMJ"},{"key":"10.1016\/j.jaci.2018.10.063_bib131","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1001\/jama.298.18.2155","article-title":"Historical comparisons of morbidity and mortality for vaccine\u2014preventable diseases in the United States","volume":"298","author":"Roush","year":"2007","journal-title":"JAMA"},{"key":"10.1016\/j.jaci.2018.10.063_bib132","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jaci.2012.04.003","article-title":"Adverse reactions to vaccines practice parameter 2012 update","volume":"130","author":"Kelso","year":"2012","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib133","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.jaci.2011.04.046","article-title":"Anaphylaxis to diphtheria, tetanus, and pertussis vaccines among children with cow's milk allergy","volume":"128","author":"Kattan","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib134","first-page":"128","article-title":"MMR vaccine and neomycin allergy","volume":"147","author":"Kwittken","year":"1993","journal-title":"Am J Dis Child"},{"key":"10.1016\/j.jaci.2018.10.063_bib135","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.vaccine.2004.06.042","article-title":"Vaccination of persons allergic to latex: a review of safety data in the Vaccine Adverse Event Reporting System (VAERS)","volume":"23","author":"Russell","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.jaci.2018.10.063_bib136","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.jaci.2011.06.028","article-title":"Comments on cow's milk allergy and diphtheria, tetanus, and pertussis vaccines","volume":"128","author":"Slater","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib137","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/S1081-1206(10)60391-2","article-title":"Thimerosal in influenza vaccine: an immediate hypersensitivity reaction","volume":"99","author":"Zheng","year":"2007","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib138","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/0091-6749(93)90344-F","article-title":"Anaphylaxis to measles, mumps, and rubella vaccine mediated by IgE to gelatin","volume":"91","author":"Kelso","year":"1993","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib139","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1034\/j.1398-9995.2001.056006536.x","article-title":"Specific IgE and IgG to gelatin in children with systemic cutaneous reactions to Japanese encephalitis vaccines","volume":"56","author":"Sakaguchi","year":"2001","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.063_bib140","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1016\/S0091-6749(96)80191-6","article-title":"Food allergy to gelatin in children with systemic immediate-type reactions, including anaphylaxis, to vaccines","volume":"98","author":"Sakaguchi","year":"1996","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib141","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0091-6749(97)70108-8","article-title":"IgE-mediated systemic reactions to gelatin included in the varicella vaccine","volume":"99","author":"Sakaguchi","year":"1997","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib142","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1067\/mai.2000.108433","article-title":"Change in gelatin content of vaccines associated with reduction in reports of allergic reactions","volume":"106","author":"Nakayama","year":"2000","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib143","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.vaccine.2004.07.016","article-title":"Post-marketing surveillance of immediate allergic reactions: polygeline-based versus polygeline-free pediatric TBE vaccine","volume":"23","author":"Zent","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.jaci.2018.10.063_bib144","doi-asserted-by":"crossref","first-page":"e1024","DOI":"10.1542\/peds.2009-2512","article-title":"Safety of influenza vaccine administration in egg-allergic patients","volume":"125","author":"Chung","year":"2010","journal-title":"Pediatrics"},{"key":"10.1016\/j.jaci.2018.10.063_bib145","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jaci.2010.05.037","article-title":"Safe vaccination of patients with egg allergy with an adjuvanted pandemic H1N1 vaccine","volume":"126","author":"Gagnon","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib146","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.anai.2012.09.011","article-title":"Safe administration of the seasonal trivalent influenza vaccine to children with severe egg allergy","volume":"109","author":"Greenhawt","year":"2012","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib147","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.anai.2011.01.024","article-title":"Safe administration of seasonal influenza vaccine to children with egg allergy of all severities","volume":"106","author":"Howe","year":"2011","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib148","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S0022-3476(98)70101-5","article-title":"Safe administration of influenza vaccine to patients with egg allergy","volume":"133","author":"James","year":"1998","journal-title":"J Pediatr"},{"key":"10.1016\/j.jaci.2018.10.063_bib149","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jaip.2012.08.008","article-title":"Generalized bullous eruption after routine vaccination in a child with diffuse cutaneous mastocytosis","volume":"1","author":"Bankova","year":"2013","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2018.10.063_bib150","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1525-1470.2008.00710.x","article-title":"Red plaque after hepatitis B vaccination","volume":"25","author":"Koh","year":"2008","journal-title":"Pediatr Dermatol"},{"key":"10.1016\/j.jaci.2018.10.063_bib151","first-page":"37","article-title":"Solitary mastocytoma arising at a hepatitis B vaccination site","volume":"63","author":"Poulton","year":"1999","journal-title":"Cutis"},{"key":"10.1016\/j.jaci.2018.10.063_bib152","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/pai.12647","article-title":"Evaluation of vaccination safety in children with mastocytosis","volume":"28","author":"Parente","year":"2017","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.jaci.2018.10.063_bib153","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1111\/cea.12882","article-title":"Vaccination management in children and adults with mastocytosis","volume":"47","author":"Zanoni","year":"2017","journal-title":"Clin Exp Allergy"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674918317317?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674918317317?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T09:18:35Z","timestamp":1758791915000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674918317317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":153,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["S0091674918317317"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2018.10.063","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adverse reactions to drugs and biologics in patients with clonal mast cell disorders: A\u00a0Work Group Report of the Mast Cells Disorder Committee, American Academy of Allergy, Asthma & Immunology","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2018.10.063","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}