{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:11:47Z","timestamp":1791497507991,"version":"4.3.4"},"reference-count":51,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"publisher","award":["521-2013-2791"],"award-info":[{"award-number":["521-2013-2791"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002794","name":"Swedish Cancer Society","doi-asserted-by":"publisher","award":["130396"],"award-info":[{"award-number":["130396"]}],"id":[{"id":"10.13039\/501100002794","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Foundation for Strategic Research","award":["ICA12-0023"],"award-info":[{"award-number":["ICA12-0023"]}]},{"DOI":"10.13039\/501100003748","name":"Swedish Society for Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003748","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002428","name":"Austrian Science Fund","doi-asserted-by":"publisher","award":["P25531-B23"],"award-info":[{"award-number":["P25531-B23"]}],"id":[{"id":"10.13039\/501100002428","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003793","name":"Swedish Heart-Lung Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003793","name":"Swedish Heart-Lung Foundation","doi-asserted-by":"publisher","award":["HLF 20150640"],"award-info":[{"award-number":["HLF 20150640"]}],"id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003793","name":"Swedish Heart-Lung Foundation","doi-asserted-by":"publisher","award":["HLF 20140469"],"award-info":[{"award-number":["HLF 20140469"]}],"id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001729","name":"Swedish Foundation for Strategic Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001729","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009252","name":"Science for Life Laboratory","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009252","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.jaci.2018.10.069","type":"journal-article","created":{"date-parts":[[2018,12,19]],"date-time":"2018-12-19T11:42:13Z","timestamp":1545219733000},"page":"2202-2214.e5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":69,"title":["Cytokine-induced endogenous production of prostaglandin D2 is essential for human group 2 innate lymphoid cell activation"],"prefix":"10.1016","volume":"143","author":[{"given":"Jovana","family":"Maric","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avinash","family":"Ravindran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Mazzurana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline","family":"Van Acker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efthymia","family":"Kokkinou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Ekoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Fauland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunnar","family":"Nilsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig E.","family":"Wheelock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven-Erik","family":"Dahl\u00e9n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nerea","family":"Ferreir\u00f3s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerd","family":"Geisslinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Friberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akos","family":"Heinemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viktoria","family":"Konya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Mj\u00f6sberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2018.10.069_bib1","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/j.jaci.2016.09.009","article-title":"Human innate lymphoid cells","volume":"138","author":"Mj\u00f6sberg","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib2","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1182\/blood-2013-11-427781","article-title":"Human innate lymphoid cells","volume":"124","author":"Hazenberg","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.jaci.2018.10.069_bib3","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.immuni.2012.08.015","article-title":"The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells","volume":"37","author":"Mj\u00f6sberg","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.jaci.2018.10.069_bib4","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.jaci.2014.06.024","article-title":"Enhanced innate type 2 immune response in peripheral blood from patients with asthma","volume":"134","author":"Bartemes","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib5","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.imlet.2016.07.006","article-title":"Lipid mediators as regulators of human ILC2 function in allergic diseases","volume":"179","author":"Konya","year":"2016","journal-title":"Immunol Lett"},{"key":"10.1016\/j.jaci.2018.10.069_bib6","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.jaci.2013.03.048","article-title":"Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production","volume":"132","author":"Doherty","year":"2013","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib7","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/j.jaci.2016.12.958","article-title":"Cysteinyl leukotriene E4 activates human group 2 innate lymphoid cells and enhances the effect of prostaglandin D2 and epithelial cytokines","volume":"140","author":"Salimi","year":"2017","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib8","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.jaci.2013.10.056","article-title":"Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells","volume":"133","author":"Xue","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib9","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.jaci.2013.09.020","article-title":"Prostaglandin D2 regulates human type 2 innate lymphoid cell chemotaxis","volume":"133","author":"Chang","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib10","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1038\/mi.2015.21","article-title":"The prostaglandin D(2) receptor CRTH2 regulates accumulation of group 2 innate lymphoid cells in the inflamed lung","volume":"8","author":"Wojno","year":"2015","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib11","doi-asserted-by":"crossref","first-page":"174ra26","DOI":"10.1126\/scitranslmed.3004812","article-title":"Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma","volume":"5","author":"Barnig","year":"2013","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jaci.2018.10.069_bib12","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1038\/ni.2104","article-title":"Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161","volume":"12","author":"Mj\u00f6sberg","year":"2011","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib13","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1084\/jem.193.2.255","article-title":"Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2","volume":"193","author":"Hirai","year":"2001","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2018.10.069_bib14","doi-asserted-by":"crossref","first-page":"227","DOI":"10.2353\/ajpath.2010.090111","article-title":"Dendritic cells express hematopoietic prostaglandin D synthase and function as a source of prostaglandin D2 in the skin","volume":"176","author":"Shimura","year":"2010","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jaci.2018.10.069_bib15","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1194\/jlr.M048553","article-title":"Adipose triglyceride lipase regulates eicosanoid production in activated human mast cells","volume":"55","author":"Dichlberger","year":"2014","journal-title":"J Lipid Res"},{"key":"10.1016\/j.jaci.2018.10.069_bib16","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.jaci.2015.08.007","article-title":"Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function","volume":"137","author":"Mitson-Salazar","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib17","doi-asserted-by":"crossref","first-page":"R146","DOI":"10.1186\/ar2581","article-title":"Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage","volume":"10","author":"Zayed","year":"2008","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.jaci.2018.10.069_bib18","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.plipres.2017.04.003","article-title":"Prostaglandin synthases: molecular characterization and involvement in prostaglandin biosynthesis","volume":"66","author":"Seo","year":"2017","journal-title":"Prog Lipid Res"},{"key":"10.1016\/j.jaci.2018.10.069_bib19","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.prostaglandins.2003.12.002","article-title":"Expression of prostaglandin D synthase and the prostaglandin D2 receptors DP and CRTH2 in human nasal mucosa","volume":"73","author":"Nantel","year":"2004","journal-title":"Prostaglandins Other Lipid Mediat"},{"key":"10.1016\/j.jaci.2018.10.069_bib20","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/j.jaci.2015.11.012","article-title":"Activated prostaglandin D2 receptors on macrophages enhance neutrophil recruitment into the lung","volume":"137","author":"Jandl","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib21","doi-asserted-by":"crossref","first-page":"6518","DOI":"10.4049\/jimmunol.1101806","article-title":"Eosinophils as a novel cell source of prostaglandin D2: autocrine role in allergic inflammation","volume":"187","author":"Luna-Gomes","year":"2011","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib22","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/nrd2266","article-title":"Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases","volume":"6","author":"Pettipher","year":"2007","journal-title":"Nat Rev Drug Discov"},{"key":"10.1016\/j.jaci.2018.10.069_bib23","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1021\/tx200336f","article-title":"11-Oxoeicosatetraenoic acid is a cyclooxygenase-2\/15-hydroxyprostaglandin dehydrogenase-derived antiproliferative eicosanoid","volume":"24","author":"Liu","year":"2011","journal-title":"Chem Res Toxicol"},{"key":"10.1016\/j.jaci.2018.10.069_bib24","doi-asserted-by":"crossref","first-page":"R121","DOI":"10.1186\/ar3851","article-title":"Limited effect of anti-rheumatic treatment on 15-prostaglandin dehydrogenase in rheumatoid arthritis synovial tissue","volume":"14","author":"Gheorghe","year":"2012","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.jaci.2018.10.069_bib25","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.jaci.2011.08.015","article-title":"D-type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on T(H)2 cells","volume":"129","author":"Sedej","year":"2012","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib26","doi-asserted-by":"crossref","first-page":"4752","DOI":"10.4049\/jimmunol.170.9.4752","article-title":"Delta 12-prostaglandin J2, a plasma metabolite of prostaglandin D2, causes eosinophil mobilization from the bone marrow and primes eosinophils for chemotaxis","volume":"170","author":"Heinemann","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib27","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1159\/000313836","article-title":"CRTH2 and D-type prostanoid receptor antagonists as novel therapeutic agents for inflammatory diseases","volume":"85","author":"Schuligoi","year":"2010","journal-title":"Pharmacology"},{"key":"10.1016\/j.jaci.2018.10.069_bib28","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3389\/fmed.2017.00104","article-title":"Prostaglandins and their receptors in eosinophil function and as therapeutic targets","volume":"4","author":"Peinhaupt","year":"2017","journal-title":"Front Med (Lausanne)"},{"key":"10.1016\/j.jaci.2018.10.069_bib29","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jaci.2017.01.045","article-title":"Vitamin D downregulates the IL-23 receptor pathway in human mucosal group 3 innate lymphoid cells","volume":"141","author":"Konya","year":"2018","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib30","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1111\/j.1398-9995.2006.01024.x","article-title":"IgE-receptor activation induces survival and Bfl-1 expression in human mast cells but not basophils","volume":"61","author":"Xiang","year":"2006","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.069_bib31","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/all.12542","article-title":"Eotaxin-3 (CCL26) exerts innate host defense activities that are modulated by mast cell proteases","volume":"70","author":"Gela","year":"2015","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.069_bib32","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1038\/ni0616-740a","article-title":"Corrigendum: the heterogeneity of human CD127(+) innate lymphoid cells revealed by single-cell RNA sequencing","volume":"17","author":"Bjorklund","year":"2016","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib33","doi-asserted-by":"crossref","first-page":"4705","DOI":"10.4049\/jimmunol.166.7.4705","article-title":"A comparison of mediators released or generated by IFN-gamma-treated human mast cells following aggregation of Fc gamma RI or Fc epsilon RI","volume":"166","author":"Okayama","year":"2001","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib34","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1111\/j.1365-2249.2008.03871.x","article-title":"Interaction between prostaglandin D and chemoattractant receptor-homologous molecule expressed on Th2 cells mediates cytokine production by Th2 lymphocytes in response to activated mast cells","volume":"156","author":"Xue","year":"2009","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib35","doi-asserted-by":"crossref","first-page":"409","DOI":"10.4168\/aair.2013.5.6.409","article-title":"The influence of IgE on cultured human mast cells","volume":"5","author":"Frandsen","year":"2013","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.1016\/j.jaci.2018.10.069_bib36","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1016\/j.jaci.2015.10.020","article-title":"Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory disease","volume":"137","author":"Buchheit","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib37","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1002\/eji.201646890","article-title":"Composition and functionality of the intrahepatic innate lymphoid cell-compartment in human nonfibrotic and fibrotic livers","volume":"47","author":"Forkel","year":"2017","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cyto.2016.01.018","article-title":"Regulation of group 2 innate lymphoid cells","volume":"87","author":"Duerr","year":"2016","journal-title":"Cytokine"},{"key":"10.1016\/j.jaci.2018.10.069_bib39","doi-asserted-by":"crossref","first-page":"e86689","DOI":"10.1172\/jci.insight.86689","article-title":"Depletion of major pathogenic cells in asthma by targeting CRTh2","volume":"1","author":"Huang","year":"2016","journal-title":"JCI Insight"},{"key":"10.1016\/j.jaci.2018.10.069_bib40","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1164\/rccm.201609-1846OC","article-title":"Mucosal type 2 innate lymphoid cells are a key component of the allergic response to aeroallergens","volume":"195","author":"Dhariwal","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2018.10.069_bib41","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.cyto.2007.09.013","article-title":"Interleukin (IL)-33 induces the release of pro-inflammatory mediators by mast cells","volume":"40","author":"Moulin","year":"2007","journal-title":"Cytokine"},{"key":"10.1016\/j.jaci.2018.10.069_bib42","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.4049\/jimmunol.164.5.2277","article-title":"Cutting edge: differential production of prostaglandin D2 by human helper T cell subsets","volume":"164","author":"Tanaka","year":"2000","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib43","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00011-004-1338-1","article-title":"Positive feedback regulation of COX-2 expression by prostaglandin metabolites","volume":"54","author":"Vichai","year":"2005","journal-title":"Inflamm Res"},{"key":"10.1016\/j.jaci.2018.10.069_bib44","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.ejphar.2006.11.058","article-title":"Differential regulation of the signaling and trafficking of the two prostaglandin D2 receptors, prostanoid DP receptor and CRTH2","volume":"557","author":"Gallant","year":"2007","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.jaci.2018.10.069_bib45","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.clim.2004.09.008","article-title":"15d-PGJ2: the anti-inflammatory prostaglandin?","volume":"114","author":"Scher","year":"2005","journal-title":"Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib46","doi-asserted-by":"crossref","first-page":"5744","DOI":"10.4049\/jimmunol.175.9.5744","article-title":"Physiological levels of 15-deoxy-Delta12,14-prostaglandin J2 prime eotaxin-induced chemotaxis on human eosinophils through peroxisome proliferator-activated receptor-gamma ligation","volume":"175","author":"Kobayashi","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib47","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aal5196","article-title":"PPAR-gamma promotes type 2 immune responses in allergy and nematode infection","volume":"2","author":"Chen","year":"2017","journal-title":"Sci Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bib48","doi-asserted-by":"crossref","first-page":"7663","DOI":"10.1074\/jbc.M310270200","article-title":"11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils","volume":"279","author":"Bohm","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jaci.2018.10.069_bibE1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jaci.2017.01.045","article-title":"Vitamin D downregulates the IL-23 receptor pathway in human mucosal group 3 innate lymphoid cells","volume":"141","author":"Konya","year":"2018","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.10.069_bibE2","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/all.12542","article-title":"Eotaxin-3 (CCL26) exerts innate host defense activities that are modulated by mast cell proteases","volume":"70","author":"Gela","year":"2015","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2018.10.069_bibE3","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1111\/j.1398-9995.2006.01024.x","article-title":"IgE-receptor activation induces survival and Bfl-1 expression in human mast cells but not basophils","volume":"61","author":"Xiang","year":"2006","journal-title":"Allergy"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009167491832774X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009167491832774X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T09:18:40Z","timestamp":1758791920000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S009167491832774X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":51,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S009167491832774X"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2018.10.069","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cytokine-induced endogenous production of prostaglandin D2 is essential for human group 2 innate lymphoid cell activation","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2018.10.069","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}