{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:18:29Z","timestamp":1784546309638,"version":"3.55.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL069174"],"award-info":[{"award-number":["HL069174"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL064937"],"award-info":[{"award-number":["HL064937"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI40600"],"award-info":[{"award-number":["AI40600"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["PO1 AI106684"],"award-info":[{"award-number":["PO1 AI106684"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["RR024153"],"award-info":[{"award-number":["RR024153"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["5U10 HL109152-05"],"award-info":[{"award-number":["5U10 HL109152-05"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Japanese Society of Allergology Fellowship"},{"name":"Sanjyukai Fellowship"},{"name":"Banyu Fellowship"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.jaci.2018.11.046","type":"journal-article","created":{"date-parts":[[2019,1,10]],"date-time":"2019-01-10T16:53:58Z","timestamp":1547139238000},"page":"2075-2085.e10","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Dysfunctional ErbB2, an EGF receptor family member, hinders repair of airway epithelial cells from asthmatic patients"],"prefix":"10.1016","volume":"143","author":[{"given":"Hideki","family":"Inoue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Hattori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuxia","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily B.","family":"Etling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian D.","family":"Modena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John B.","family":"Trudeau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Holguin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally E.","family":"Wenzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2018.11.046_bib1","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1038\/nm.2737","article-title":"The airway epithelium in asthma","volume":"18","author":"Lambrecht","year":"2012","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2018.11.046_bib2","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1378\/chest.12-1944","article-title":"Epithelial injury and repair in airways diseases","volume":"144","author":"Grainge","year":"2013","journal-title":"Chest"},{"key":"10.1016\/j.jaci.2018.11.046_bib3","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.jaci.2011.05.038","article-title":"Defective epithelial barrier function in asthma","volume":"128","author":"Xiao","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.11.046_bib4","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1164\/ajrccm.163.2.2004039","article-title":"Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression","volume":"163","author":"Ordonez","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2018.11.046_bib5","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1038\/nmat4357","article-title":"Unjamming and cell shape in the asthmatic airway epithelium","volume":"14","author":"Park","year":"2015","journal-title":"Nat Mater"},{"key":"10.1016\/j.jaci.2018.11.046_bib6","doi-asserted-by":"crossref","first-page":"15858","DOI":"10.1073\/pnas.0707413104","article-title":"Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids","volume":"104","author":"Woodruff","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jaci.2018.11.046_bib7","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1164\/rccm.201406-1099OC","article-title":"Gene expression in relation to exhaled nitric oxide identifies novel asthma phenotypes with unique biomolecular pathways","volume":"190","author":"Modena","year":"2014","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2018.11.046_bib8","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1164\/rccm.201607-1407OC","article-title":"Gene expression correlated with severe asthma characteristics reveals heterogeneous mechanisms of severe disease","volume":"195","author":"Modena","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2018.11.046_bib9","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.jaci.2012.07.052","article-title":"Epigenetic mechanisms and the development of asthma","volume":"130","author":"Yang","year":"2012","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.11.046_bib10","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1056\/NEJMoa0906312","article-title":"A large-scale, consortium-based genomewide association study of asthma","volume":"363","author":"Moffatt","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2018.11.046_bib11","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1136\/thoraxjnl-2011-201262","article-title":"Genome-wide association study to identify genetic determinants of severe asthma","volume":"67","author":"Wan","year":"2012","journal-title":"Thorax"},{"key":"10.1016\/j.jaci.2018.11.046_bib12","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/s41588-017-0014-7","article-title":"Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks","volume":"50","author":"Demenais","year":"2018","journal-title":"Nat Genet"},{"key":"10.1016\/j.jaci.2018.11.046_bib13","doi-asserted-by":"crossref","first-page":"e90151","DOI":"10.1172\/jci.insight.90151","article-title":"DNA methylation in lung cells is associated with asthma endotypes and genetic risk","volume":"1","author":"Nicodemus-Johnson","year":"2016","journal-title":"JCI Insight"},{"key":"10.1016\/j.jaci.2018.11.046_bib14","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/BF02633985","article-title":"Serial culturing of human bronchial epithelial cells derived from biopsies","volume":"29A","author":"de Jong","year":"1993","journal-title":"Vitro Cell Dev Biol Anim"},{"issue":"suppl\u00a04","key":"10.1016\/j.jaci.2018.11.046_bib15","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/S0959-8049(01)00230-1","article-title":"The EGFR family and its ligands in human cancer. Signalling mechanisms and therapeutic opportunities","volume":"37","author":"Yarden","year":"2001","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.jaci.2018.11.046_bib16","doi-asserted-by":"crossref","first-page":"2931","DOI":"10.1091\/mbc.e05-09-0895","article-title":"Muc4-ErbB2 complex formation and signaling in polarized CACO-2 epithelial cells indicate that Muc4 acts as an unorthodox ligand for ErbB2","volume":"17","author":"Ramsauer","year":"2006","journal-title":"Mol Biol Cell"},{"key":"10.1016\/j.jaci.2018.11.046_bib17","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1096\/fasebj.14.10.1362","article-title":"Involvement of the epidermal growth factor receptor in epithelial repair in asthma","volume":"14","author":"Puddicombe","year":"2000","journal-title":"FASEB J"},{"key":"10.1016\/j.jaci.2018.11.046_bib18","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1172\/JCI25167","article-title":"Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals","volume":"116","author":"Tyner","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2018.11.046_bib19","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1164\/rccm.200907-1071OC","article-title":"Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium","volume":"181","author":"Kicic","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2018.11.046_bib20","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1165\/rcmb.4715","article-title":"Increased expression of p21(waf) cyclin-dependent kinase inhibitor in asthmatic bronchial epithelium","volume":"28","author":"Puddicombe","year":"2003","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jaci.2018.11.046_bib21","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.humimm.2012.11.003","article-title":"Pathway analysis of genome-wide association study on asthma","volume":"74","author":"Song","year":"2013","journal-title":"Hum Immunol"},{"key":"10.1016\/j.jaci.2018.11.046_bib22","doi-asserted-by":"crossref","first-page":"L175","DOI":"10.1152\/ajplung.00547.2005","article-title":"Differentiation of human airway epithelia is dependent on erbB2","volume":"291","author":"Vermeer","year":"2006","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1016\/j.jaci.2018.11.046_bib23","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1016\/j.yexcr.2011.05.010","article-title":"Heregulin activation of ErbB2\/ErbB3 signaling potentiates the integrity of airway epithelial barrier","volume":"317","author":"Gon","year":"2011","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.jaci.2018.11.046_bib24","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1038\/378394a0","article-title":"Requirement for neuregulin receptor erbB2 in neural and cardiac development","volume":"378","author":"Lee","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.jaci.2018.11.046_bib25","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1111\/j.1365-2222.2008.02969.x","article-title":"IL-13 induced increases in nitrite levels are primarily driven by increases in inducible nitric oxide synthase as compared with effects on arginases in human primary bronchial epithelial cells","volume":"38","author":"Chibana","year":"2008","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2018.11.046_bib26","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1016\/j.jaci.2006.01.049","article-title":"Selective downregulation of prostaglandin E2-related pathways by the Th2 cytokine IL-13","volume":"117","author":"Trudeau","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.11.046_bib27","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1165\/ajrcmb.25.6.4659","article-title":"Interleukin-13 induces proliferation of human airway epithelial cells in\u00a0vitro via a mechanism mediated by transforming growth factor-alpha","volume":"25","author":"Booth","year":"2001","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jaci.2018.11.046_bib28","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/S0002-9440(10)63371-8","article-title":"Transforming growth factor-beta2 induces bronchial epithelial mucin expression in asthma","volume":"165","author":"Chu","year":"2004","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jaci.2018.11.046_bib29","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/j.1442-2042.2006.01342.x","article-title":"Novel HER2 selective tyrosine kinase inhibitor, TAK-165, inhibits bladder, kidney and androgen-independent prostate cancer in\u00a0vitro and in\u00a0vivo","volume":"13","author":"Nagasawa","year":"2006","journal-title":"Int J Urol"},{"key":"10.1016\/j.jaci.2018.11.046_bib30","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/nrc1609","article-title":"ERBB receptors and cancer: the complexity of targeted inhibitors","volume":"5","author":"Hynes","year":"2005","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.jaci.2018.11.046_bib31","doi-asserted-by":"crossref","first-page":"50004","DOI":"10.1074\/jbc.M404252200","article-title":"Cooperation between fibroblast growth factor receptor-4 and ErbB2 in regulation of cyclin D1 translation","volume":"279","author":"Koziczak","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jaci.2018.11.046_bib32","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1164\/rccm.201201-0027OC","article-title":"Airway epithelial miRNA expression is altered in asthma","volume":"186","author":"Solberg","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2018.11.046_bib33","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1165\/rcmb.4850","article-title":"Neuregulin-1 activates the JAK-STAT pathway and regulates lung epithelial cell proliferation","volume":"27","author":"Liu","year":"2002","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jaci.2018.11.046_bib34","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.jaci.2009.08.044","article-title":"Tissue remodeling induced by hypersecreted epidermal growth factor and amphiregulin in the airway after an acute asthma attack","volume":"124","author":"Enomoto","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.11.046_bib35","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nrc2656","article-title":"Novel anticancer targets: revisiting ERBB2 and discovering ERBB3","volume":"9","author":"Baselga","year":"2009","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.jaci.2018.11.046_bib36","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1126\/science.3798106","article-title":"Human breast cancer: correlation of relapse and survival with amplification of the HER-2\/neu oncogene","volume":"235","author":"Slamon","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.jaci.2018.11.046_bib37","doi-asserted-by":"crossref","first-page":"6102","DOI":"10.1038\/sj.onc.1203973","article-title":"Molecular mechanisms underlying ErbB2\/HER2 action in breast cancer","volume":"19","author":"Harari","year":"2000","journal-title":"Oncogene"},{"key":"10.1016\/j.jaci.2018.11.046_bib38","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/nature01440","article-title":"Segregation of receptor and ligand regulates activation of epithelial growth factor receptor","volume":"422","author":"Vermeer","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.jaci.2018.11.046_bib39","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1677\/erc.0.0080011","article-title":"The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification","volume":"8","author":"Prenzel","year":"2001","journal-title":"Endocr Relat Cancer"},{"key":"10.1016\/j.jaci.2018.11.046_bib40","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1038\/s41598-018-19837-6","article-title":"Persistent\u00a0activation of interlinked type 2 airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic asthmatics","volume":"8","author":"Jones","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.jaci.2018.11.046_bib41","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1111\/j.1365-2222.2008.03093.x","article-title":"Dysregulated repair in asthmatic paediatric airway epithelial cells: the role of plasminogen activator inhibitor-1","volume":"38","author":"Stevens","year":"2008","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2018.11.046_bib42","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1096\/fj.07-8276com","article-title":"EGF regulates plasminogen activator inhibitor-1 (PAI-1) by a pathway involving c-Src, PKCdelta, and sphingosine kinase 1 in glioblastoma cells","volume":"22","author":"Paugh","year":"2008","journal-title":"FASEB J"},{"key":"10.1016\/j.jaci.2018.11.046_bib43","doi-asserted-by":"crossref","first-page":"304","DOI":"10.3390\/cells3020304","article-title":"Mechanisms of activation of receptor tyrosine kinases: monomers or dimers","volume":"3","author":"Maruyama","year":"2014","journal-title":"Cells"},{"key":"10.1016\/j.jaci.2018.11.046_bibE1","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1164\/rccm.200906-0896OC","article-title":"Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program","volume":"181","author":"Moore","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2018.11.046_bibE2","first-page":"225","article-title":"Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, November 1986","volume":"136","year":"1987","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.jaci.2018.11.046_bibE3","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1183\/09031936.00202013","article-title":"International ERS\/ATS guidelines on definition, evaluation and treatment of severe asthma","volume":"43","author":"Chung","year":"2014","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaci.2018.11.046_bibE4","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1183\/09031936.00080312","article-title":"Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations","volume":"40","author":"Quanjer","year":"2012","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaci.2018.11.046_bibE5","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1111\/j.1365-2222.2008.02969.x","article-title":"IL-13 induced increases in nitrite levels are primarily driven by increases in inducible nitric oxide synthase as compared with effects on arginases in human primary bronchial epithelial cells","volume":"38","author":"Chibana","year":"2008","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2018.11.046_bibE6","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1016\/j.jaci.2006.01.049","article-title":"Selective downregulation of prostaglandin E2-related pathways by the Th2 cytokine IL-13","volume":"117","author":"Trudeau","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2018.11.046_bibE7","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1165\/ajrcmb.25.6.4659","article-title":"Interleukin-13 induces proliferation of human airway epithelial cells in\u00a0vitro via a mechanism mediated by transforming growth factor-alpha","volume":"25","author":"Booth","year":"2001","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jaci.2018.11.046_bibE8","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/S0002-9440(10)63371-8","article-title":"Transforming growth factor-beta2 induces bronchial epithelial mucin expression in asthma","volume":"165","author":"Chu","year":"2004","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jaci.2018.11.046_bibE9","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1183\/09031936.00129107","article-title":"Selection of housekeeping genes for real-time PCR in atopic human bronchial epithelial cells","volume":"32","author":"He","year":"2008","journal-title":"Eur Respir J"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674919300089?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674919300089?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T09:20:03Z","timestamp":1758792003000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674919300089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":52,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S0091674919300089"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2018.11.046","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dysfunctional ErbB2, an EGF receptor family member, hinders repair of airway epithelial cells from asthmatic patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2018.11.046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}