{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T14:54:47Z","timestamp":1782744887227,"version":"3.54.5"},"reference-count":18,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T00:00:00Z","timestamp":1602720000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.jaci.2020.09.037","type":"journal-article","created":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T01:05:22Z","timestamp":1603155922000},"page":"1490-1496.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Increased group 2 innate lymphoid cells in peripheral blood of adults with mastocytosis"],"prefix":"10.1016","volume":"147","author":[{"given":"Esmee K.","family":"van der Ploeg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maud A.W.","family":"Hermans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent H.J.","family":"van der Velden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willem A.","family":"Dik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul L.A.","family":"van Daele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1060-5607","authenticated-orcid":false,"given":"Ralph","family":"Stadhouders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2020.09.037_bib1","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/ajh.25371","article-title":"Systemic mastocytosis in adults: 2019 update on diagnosis, risk stratification and management","volume":"94","author":"Pardanani","year":"2019","journal-title":"Am J Hematol"},{"key":"10.1016\/j.jaci.2020.09.037_bib2","doi-asserted-by":"crossref","first-page":"18250","DOI":"10.18632\/oncotarget.4213","article-title":"Mastocytosis: a mutated KIT receptor induced myeloproliferative disorder","volume":"6","author":"Chatterjee","year":"2015","journal-title":"Oncotarget"},{"key":"10.1016\/j.jaci.2020.09.037_bib3","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.anai.2019.12.020","article-title":"Psychological functioning and quality of life in patients with mastocytosis: a cross-sectional study","volume":"124","author":"Vermeiren","year":"2020","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaci.2020.09.037_bib4","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1111\/j.1398-9995.2012.02809.x","article-title":"Tryptase and histamine metabolites as diagnostic indicators of indolent systemic mastocytosis without skin lesions","volume":"67","author":"van Doormaal","year":"2012","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2020.09.037_bib5","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1189\/jlb.5BT0814-374R","article-title":"At the bench: understanding group 2 innate lymphoid cells in disease","volume":"97","author":"Doherty","year":"2015","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.jaci.2020.09.037_bib6","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1002\/eji.201848006","article-title":"Expression of c-Kit discriminates between two functionally distinct subsets of human type 2 innate lymphoid cells","volume":"49","author":"Hochdorfer","year":"2019","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jaci.2020.09.037_bib7","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.immuni.2017.04.017","article-title":"Mast cells are crucial for induction of group 2 innate lymphoid cells and clearance of helminth infections","volume":"46","author":"Shimokawa","year":"2017","journal-title":"Immunity"},{"key":"10.1016\/j.jaci.2020.09.037_bib8","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1182\/blood-2016-09-731893","article-title":"Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts","volume":"129","author":"Valent","year":"2017","journal-title":"Blood"},{"key":"10.1016\/j.jaci.2020.09.037_bib9","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.jmoldx.2010.10.004","article-title":"Improved detection of the KIT D816V mutation in patients with systemic mastocytosis using a quantitative and highly sensitive real-time qPCR assay","volume":"13","author":"Kristensen","year":"2011","journal-title":"J Mol Diagn"},{"key":"10.1016\/j.jaci.2020.09.037_bib10","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/imr.12634","article-title":"Mast cells as sources of cytokines, chemokines, and growth factors","volume":"282","author":"Mukai","year":"2018","journal-title":"Immunol Rev"},{"key":"10.1016\/j.jaci.2020.09.037_bib11","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.jaci.2013.10.056","article-title":"Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells","volume":"133","author":"Xue","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2020.09.037_bib12","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1365-2133.1995.tb02616.x","article-title":"Expression of stem cell factor in cutaneous mastocytosis","volume":"133","author":"Hamann","year":"1995","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2020.09.037_bib13","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.coi.2014.10.008","article-title":"Dermal group 2 innate lymphoid\u00a0cells in atopic dermatitis and allergy","volume":"31","author":"Roediger","year":"2014","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.jaci.2020.09.037_bib14","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20191172","article-title":"Tissue-specific pathways extrude activated ILC2s to disseminate type 2 immunity","volume":"217","author":"Ricardo-Gonzalez","year":"2020","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2020.09.037_bib15","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1038\/s41590-019-0423-0","article-title":"c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies","volume":"20","author":"Bernink","year":"2019","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaci.2020.09.037_bib16","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1182\/blood-2016-09-731893","article-title":"Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts","volume":"129","author":"Valent","year":"2017","journal-title":"Blood"},{"key":"10.1016\/j.jaci.2020.09.037_bib17","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.jmoldx.2010.10.004","article-title":"Improved detection of the KIT D816V mutation in patients with systemic mastocytosis using a quantitative and highly sensitive real-time qPCR assay","volume":"13","author":"Kristensen","year":"2011","journal-title":"J Mol Diagn"},{"key":"10.1016\/j.jaci.2020.09.037_bib18","first-page":"142","article-title":"Immunophenotyping of mast cells: a sensitive and specific diagnostic tool for systemic mastocytosis","volume":"67","author":"van Daele","year":"2009","journal-title":"Neth J Med"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674920314159?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674920314159?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T09:33:59Z","timestamp":1758792839000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674920314159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["S0091674920314159"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2020.09.037","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Increased group 2 innate lymphoid cells in peripheral blood of adults with mastocytosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2020.09.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology.","name":"copyright","label":"Copyright"}]}}