{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T06:33:49Z","timestamp":1793255629157,"version":"4.5.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI15C1736"],"award-info":[{"award-number":["HI15C1736"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2019R1A2C2087574"],"award-info":[{"award-number":["NRF-2019R1A2C2087574"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["SRC 2017R1A5A1014560"],"award-info":[{"award-number":["SRC 2017R1A5A1014560"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.jaci.2021.09.031","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T14:49:07Z","timestamp":1634827747000},"page":"1253-1269.e8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":58,"title":["A unique population of neutrophils generated by air pollutant\u2013induced lung damage exacerbates airway inflammation"],"prefix":"10.1016","volume":"149","author":[{"given":"Jae Woo","family":"Shin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seokjin","family":"Ham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun Mi","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Hoon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Chan","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Hyung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Heon","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hye Ryun","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You-Me","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doo Hyun","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeonseok","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoe-Sik","family":"Bae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Soo","family":"Bae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae-Young","family":"Roh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taesoo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5978-512X","authenticated-orcid":false,"given":"Hye Young","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2021.09.031_bib1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1586\/17476348.2016.1114417","article-title":"Is asthma prevalence still increasing?","volume":"10","author":"Lundback","year":"2016","journal-title":"Expert Rev Respir Med"},{"key":"10.1016\/j.jaci.2021.09.031_bib2","doi-asserted-by":"crossref","first-page":"15025","DOI":"10.1038\/nrdp.2015.25","volume":"1","author":"Holgate","year":"2015","journal-title":"Asthma. Nat Rev Dis Primers"},{"key":"10.1016\/j.jaci.2021.09.031_bib3","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1183\/09031936.00138707","article-title":"Global strategy for asthma management and prevention: GINA executive summary","volume":"31","author":"Bateman","year":"2008","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaci.2021.09.031_bib4","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1111\/j.1365-2222.2005.02328.x","article-title":"Environmental risk factors and allergic bronchial asthma","volume":"35","author":"D\u2019Amato","year":"2005","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2021.09.031_bib5","doi-asserted-by":"crossref","first-page":"2730","DOI":"10.1016\/j.ajpath.2011.08.008","article-title":"Diesel exhaust particulates exacerbate asthma-like inflammation by increasing CXC chemokines","volume":"179","author":"Kim","year":"2011","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jaci.2021.09.031_bib6","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1097\/MOP.0000000000000286","article-title":"Air pollution and allergic diseases","volume":"27","author":"Brandt","year":"2015","journal-title":"Curr Opin Pediatr"},{"key":"10.1016\/j.jaci.2021.09.031_bib7","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1172\/JCI124612","article-title":"Environmental exposures and mechanisms in allergy and asthma development","volume":"129","author":"Murrison","year":"2019","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2021.09.031_bib8","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1038\/nm.2678","article-title":"Asthma phenotypes: the evolution from clinical to molecular approaches","volume":"18","author":"Wenzel","year":"2012","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2021.09.031_bib9","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s12016-018-8712-1","article-title":"Understanding asthma phenotypes, endotypes, and mechanisms of disease","volume":"56","author":"Kuruvilla","year":"2019","journal-title":"Clin Rev Allergy Immunol"},{"issue":"suppl\u00a05","key":"10.1016\/j.jaci.2021.09.031_bib10","doi-asserted-by":"crossref","first-page":"S236","DOI":"10.1513\/AnnalsATS.201405-218AW","article-title":"Dendritic cell and epithelial cell interactions at the origin of murine asthma","volume":"11","author":"Lambrecht","year":"2014","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.jaci.2021.09.031_bib11","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1056\/NEJM199010113231505","article-title":"Eosinophilic inflammation in asthma","volume":"323","author":"Bousquet","year":"1990","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.jaci.2021.09.031_bib12","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.MCHD-0053-2016","article-title":"Myeloid cells in asthma","volume":"5","author":"Lambrecht","year":"2017","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.jaci.2021.09.031_bib13","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/nm.2755","article-title":"IgE and mast cells in allergic disease","volume":"18","author":"Galli","year":"2012","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2021.09.031_bib14","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1183\/13993003.00336-2016","article-title":"Blood granulocyte patterns as predictors of asthma phenotypes in adults from the EGEA study","volume":"48","author":"Nadif","year":"2016","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaci.2021.09.031_bib15","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.jaci.2010.02.008","article-title":"Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes","volume":"125","author":"Hastie","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2021.09.031_bib16","doi-asserted-by":"crossref","first-page":"4089","DOI":"10.4049\/jimmunol.181.6.4089","article-title":"TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice","volume":"181","author":"McKinley","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2021.09.031_bib17","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jaci.2008.07.007","article-title":"Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages","volume":"122","author":"Goleva","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2021.09.031_bib18","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/nm.3423","article-title":"Interleukin-17\u2013producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity","volume":"20","author":"Kim","year":"2014","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2021.09.031_bib19","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/nm.2684","article-title":"IL-17A produced by alphabeta T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction","volume":"18","author":"Kudo","year":"2012","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2021.09.031_bib20","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.coi.2018.05.006","article-title":"Role of neutrophils in allergic asthma","volume":"54","author":"Radermecker","year":"2018","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.jaci.2021.09.031_bib21","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1038\/nm.4332","article-title":"Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation","volume":"23","author":"Toussaint","year":"2017","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2021.09.031_bib22","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/nri.2017.105","article-title":"Neutrophil extracellular traps in immunity and disease","volume":"18","author":"Papayannopoulos","year":"2018","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jaci.2021.09.031_bib23","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1136\/thx.17.4.320","article-title":"Quantitative methods in the study of pulmonary pathology","volume":"17","author":"Dunnill","year":"1962","journal-title":"Thorax"},{"key":"10.1016\/j.jaci.2021.09.031_bib24","doi-asserted-by":"crossref","DOI":"10.1002\/0471142956.cy1017s53","article-title":"Web-based analysis and publication of flow cytometry experiments","author":"Kotecha","year":"2010","journal-title":"Curr Protoc Cytom"},{"issue":"36","key":"10.1016\/j.jaci.2021.09.031_bib25","first-page":"1724","article-title":"Neutrophil extracellular traps: how to generate and visualize them","author":"Brinkmann","year":"2010","journal-title":"J Vis Exp"},{"key":"10.1016\/j.jaci.2021.09.031_bib26","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1084\/jem.20020656","article-title":"Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in\u00a0vivo","volume":"195","author":"Yu","year":"2002","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2021.09.031_bib27","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1093\/bioinformatics\/btp101","article-title":"ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks","volume":"25","author":"Bindea","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaci.2021.09.031_bib28","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res"},{"key":"10.1016\/j.jaci.2021.09.031_bib29","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.ejmech.2004.01.007","article-title":"Structure\u2013activity relationships of analogues of NF449 confirm NF449 as the most potent and selective known P2X1 receptor antagonist","volume":"39","author":"Kassack","year":"2004","journal-title":"Eur J Med Chem"},{"issue":"7500","key":"10.1016\/j.jaci.2021.09.031_bib30","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/nature13085","article-title":"Nucleotide signalling during inflammation","volume":"509","author":"Idzko","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.jaci.2021.09.031_bib31","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/nm.4027","article-title":"Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease","volume":"22","author":"Lood","year":"2016","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2021.09.031_bib32","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.celrep.2014.06.044","article-title":"A myeloperoxidase-containing complex regulates neutrophil elastase release and actin dynamics during NETosis","volume":"8","author":"Metzler","year":"2014","journal-title":"Cell Rep"},{"key":"10.1016\/j.jaci.2021.09.031_bib33","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jaci.2017.04.022","article-title":"Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease","volume":"141","author":"Dicker","year":"2018","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2021.09.031_bib34","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s12931-015-0221-7","article-title":"Neutrophil extracellular trap (NET) formation characterises stable and exacerbated COPD and correlates with airflow limitation","volume":"16","author":"Grabcanovic-Musija","year":"2015","journal-title":"Respir Res"},{"key":"10.1016\/j.jaci.2021.09.031_bib35","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/nchembio.1735","article-title":"Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation","volume":"11","author":"Lewis","year":"2015","journal-title":"Nat Chem Biol"},{"issue":"5548","key":"10.1016\/j.jaci.2021.09.031_bib36","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1126\/science.294.5548.1871","article-title":"Prostaglandins and leukotrienes: advances in eicosanoid biology","volume":"294","author":"Funk","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.jaci.2021.09.031_bib37","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1139\/y89-073","article-title":"L-663,536 (MK-886)(3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor","volume":"67","author":"Gillard","year":"1989","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1016\/j.jaci.2021.09.031_bib38","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1056\/NEJM199807163390302","article-title":"Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction","volume":"339","author":"Leff","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2021.09.031_bib39","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1093\/glycob\/cwi097","article-title":"Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6\u2032-sulfo-sialyl Lewis X as a preferred glycan ligand","volume":"15","author":"Tateno","year":"2005","journal-title":"Glycobiology"},{"key":"10.1016\/j.jaci.2021.09.031_bib40","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0062985","article-title":"The coexistence of asthma and chronic obstructive pulmonary disease (COPD): prevalence and risk factors in young, middle-aged and elderly people from the general population","volume":"8","author":"de Marco","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jaci.2021.09.031_bib41","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1186\/1465-9921-12-127","article-title":"The clinical features of the overlap between COPD and asthma","volume":"12","author":"Hardin","year":"2011","journal-title":"Respir Res"},{"key":"10.1016\/j.jaci.2021.09.031_bib42","doi-asserted-by":"crossref","first-page":"279","DOI":"10.3109\/02770903.2011.555576","article-title":"Overlap syndrome of asthma and COPD predicts low quality of life","volume":"48","author":"Kauppi","year":"2011","journal-title":"J Asthma"},{"key":"10.1016\/j.jaci.2021.09.031_bib43","doi-asserted-by":"crossref","first-page":"4798","DOI":"10.21037\/jtd.2017.11.113","article-title":"Severe asthma and asthma-COPD overlap: a double agent or identical twins?","volume":"9","author":"Xia","year":"2017","journal-title":"J Thorac Dis"},{"issue":"6367","key":"10.1016\/j.jaci.2021.09.031_bib44","doi-asserted-by":"crossref","DOI":"10.1126\/science.aal5081","article-title":"Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils","volume":"358","author":"Engblom","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.jaci.2021.09.031_bib45","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.bbrc.2020.03.122","article-title":"A novel Siglec-F+ neutrophil subset in the mouse nasal mucosa exhibits an activated phenotype and is increased in an allergic rhinitis model","volume":"526","author":"Matsui","year":"2020","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jaci.2021.09.031_bib46","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/ni.1892","article-title":"The many paths to asthma: phenotype shaped by innate and adaptive immunity","volume":"11","author":"Kim","year":"2010","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaci.2021.09.031_bib47","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1016\/j.immuni.2019.03.009","article-title":"Single-cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species","volume":"50","author":"Zilionis","year":"2019","journal-title":"Immunity"},{"key":"10.1016\/j.jaci.2021.09.031_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108164","article-title":"Tumor-promoting Ly-6G+ SiglecFhigh cells are mature and long-lived neutrophils","volume":"32","author":"Pfirschke","year":"2020","journal-title":"Cell Rep"},{"issue":"26","key":"10.1016\/j.jaci.2021.09.031_bib49","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aao4747","article-title":"Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma","volume":"3","author":"Krishnamoorthy","year":"2018","journal-title":"Sci Immunol"},{"key":"10.1016\/j.jaci.2021.09.031_bib50","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/cea.12859","article-title":"Neutrophil autophagy and extracellular DNA traps contribute to airway inflammation in severe asthma","volume":"47","author":"Pham","year":"2017","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2021.09.031_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0123584","article-title":"The importance of bacterial and viral infections associated with adult asthma exacerbations in clinical practice","volume":"10","author":"Iikura","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jaci.2021.09.031_bib52","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1164\/rccm.200304-503OC","article-title":"Cigarette smoking impairs the therapeutic response to oral corticosteroids in chronic asthma","volume":"168","author":"Chaudhuri","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2021.09.031_bib53","doi-asserted-by":"crossref","first-page":"3790","DOI":"10.1182\/blood-2011-10-384826","article-title":"Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes","volume":"119","author":"Laidlaw","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.jaci.2021.09.031_bib54","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1164\/ajrccm.163.1.9912019","article-title":"Leukotriene D4-induced activation of smooth-muscle cells from human bronchi is partly Ca2+-independent","volume":"163","author":"Accomazzo","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2021.09.031_bib55","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1056\/NEJMra071371","volume":"357","author":"Peters-Golden","year":"2007","journal-title":"Leukotrienes. N Engl J Med"},{"key":"10.1016\/j.jaci.2021.09.031_bib56","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1016\/j.jaci.2012.01.057","article-title":"Human TH2 cells respond to cysteinyl leukotrienes through selective expression of cysteinyl leukotriene receptor 1","volume":"129","author":"Parmentier","year":"2012","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2021.09.031_bib57","doi-asserted-by":"crossref","first-page":"12937","DOI":"10.1038\/s41598-019-49419-z","article-title":"G-CSF and GM-CSF modify neutrophil functions at concentrations found in cystic fibrosis","volume":"9","author":"Castellani","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.jaci.2021.09.031_bib58","doi-asserted-by":"crossref","first-page":"3064","DOI":"10.3389\/fimmu.2019.03064","article-title":"IL8 and PMA Trigger the regulation of different biological processes in granulocyte activation","volume":"10","author":"Degroote","year":"2019","journal-title":"Front Immunol"},{"key":"10.1016\/j.jaci.2021.09.031_bib59","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1146\/annurev-pathmechdis-012419-032847","article-title":"DAMPs, PAMPs, and LAMPs in immunity and sterile inflammation","volume":"15","author":"Zindel","year":"2020","journal-title":"Annu Rev Pathol"},{"key":"10.1016\/j.jaci.2021.09.031_bib60","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/s41577-019-0215-7","article-title":"DAMP-sensing receptors in sterile inflammation and inflammatory diseases","volume":"20","author":"Gong","year":"2020","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jaci.2021.09.031_bib61","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/nrm.2017.26","article-title":"Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes","volume":"18","author":"Clapier","year":"2017","journal-title":"Nat Rev Mol Cell Biol"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674921015207?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674921015207?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T09:33:52Z","timestamp":1758792832000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674921015207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":61,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["S0091674921015207"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2021.09.031","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A unique population of neutrophils generated by air pollutant\u2013induced lung damage exacerbates airway inflammation","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2021.09.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}