{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:17:00Z","timestamp":1780103820989,"version":"3.54.0"},"reference-count":10,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100008374","name":"CFAR","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008374","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.jaci.2021.10.025","type":"journal-article","created":{"date-parts":[[2021,11,2]],"date-time":"2021-11-02T02:54:32Z","timestamp":1635821672000},"page":"565-568","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Immune health grades: Finding resilience in the COVID-19 pandemic and beyond"],"prefix":"10.1016","volume":"149","author":[{"given":"Vincent C.","family":"Marconi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkatesh","family":"Krishnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Wesley","family":"Ely","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monty","family":"Montano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2021.10.025_bib1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0241825","article-title":"Development and validation of a 30-day mortality index based on pre-existing medical administrative data from 13,323 COVID-19 patients: the Veterans Health Administration COVID-19 (VACO) Index","volume":"15","author":"King","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.jaci.2021.10.025_bib2","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1016\/j.jaci.2021.08.021","article-title":"Immunologic resilience and COVID-19 survival advantage","volume":"148","author":"Lee","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2021.10.025_bib3","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/s41584-020-00563-1","article-title":"Unravelling the complex genetic regulation of immune cells","volume":"17","author":"Ramos","year":"2021","journal-title":"Nat Rev Rheumatol"},{"key":"10.1016\/j.jaci.2021.10.025_bib4","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1038\/s41586-021-03234-7","article-title":"Global absence and targeting of protective immune states in severe COVID-19","volume":"591","author":"Combes","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.jaci.2021.10.025_bib5","doi-asserted-by":"crossref","DOI":"10.1126\/science.abc8511","article-title":"Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications","volume":"369","author":"Mathew","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.jaci.2021.10.025_bib6","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jaci.2020.08.031","article-title":"Characterization of the cytokine storm reflects hyperinflammatory endothelial dysfunction in COVID-19","volume":"147","author":"Sims","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2021.10.025_bib7","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s13073-018-0554-1","article-title":"KLRD1-expressing natural killer cells predict influenza susceptibility","volume":"10","author":"Bongen","year":"2018","journal-title":"Genome Med"},{"key":"10.1016\/j.jaci.2021.10.025_bib8","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/s41591-019-0381-y","article-title":"A clinically meaningful metric of immune age derived from high-dimensional longitudinal monitoring","volume":"25","author":"Alpert","year":"2019","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2021.10.025_bib9","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1038\/s43587-021-00082-y","article-title":"An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging","volume":"1","author":"Sayed","year":"2021","journal-title":"Nature Aging"},{"key":"10.1016\/j.jaci.2021.10.025_bib10","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/s41577-020-0285-6","article-title":"Defining trained immunity and its role in health and disease","volume":"20","author":"Netea","year":"2020","journal-title":"Nat Rev Immunol"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674921016833?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674921016833?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T09:36:03Z","timestamp":1758792963000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674921016833"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["S0091674921016833"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2021.10.025","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Immune health grades: Finding resilience in the COVID-19 pandemic and beyond","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2021.10.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2021.08.021","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}