{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T11:38:55Z","timestamp":1790509135165,"version":"4.1.0"},"reference-count":82,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001348","name":"Agency for Science Technology and Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001348","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011744","name":"National University Health System","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011744","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["MH 095:003008-225"],"award-info":[{"award-number":["MH 095:003008-225"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["MOH-000269"],"award-info":[{"award-number":["MOH-000269"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001352","name":"National University of Singapore","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001352","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020820","name":"Institute for Health Innovation and Technology, National University of Singapore","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020820","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018366","name":"Universitas Nasional","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018366","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.jaci.2022.01.031","type":"journal-article","created":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T11:43:55Z","timestamp":1647690235000},"page":"894-908","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Shared signatures and divergence in skin microbiomes of children with atopic dermatitis and their caregivers"],"prefix":"10.1016","volume":"150","author":[{"given":"Minghao","family":"Chia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad N.M.","family":"Naim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angeline S.L.","family":"Tay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karmun","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kean Lee","family":"Chew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"See Jie","family":"Yow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John E.A.","family":"Common","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niranjan","family":"Nagarajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1037-6143","authenticated-orcid":false,"given":"Elizabeth Huiwen","family":"Tham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2022.01.031_bib1","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.aller.2011.11.004","article-title":"Changes over time in the relationship between symptoms of asthma, rhinoconjunctivitis and eczema: a global perspective from the International Study of Asthma and Allergies in Childhood (ISAAC)","volume":"40","author":"Asher","year":"2012","journal-title":"Allergol Immunopathol (Madr)"},{"key":"10.1016\/j.jaci.2022.01.031_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41572-018-0001-z","article-title":"Atopic dermatitis","volume":"4","author":"Weidinger","year":"2018","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.jaci.2022.01.031_bib3","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0140-6736(20)31286-1","article-title":"Atopic dermatitis","volume":"396","author":"Langan","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.jaci.2022.01.031_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1525-1470.2007.00572.x","article-title":"The socioeconomic impact of atopic dermatitis in the United States: a systematic review","volume":"25","author":"Mancini","year":"2008","journal-title":"Pediatr Dermatol"},{"issue":"suppl\u00a01","key":"10.1016\/j.jaci.2022.01.031_bib5","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1159\/000370221","article-title":"Treatment of childhood atopic dermatitis and economic burden of illness in Asia Pacific countries","volume":"66","author":"Lee","year":"2015","journal-title":"Ann Nutr Metab"},{"key":"10.1016\/j.jaci.2022.01.031_bib6","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1056\/NEJM199808203390806","article-title":"Staphylococcus aureus infections","volume":"339","author":"Lowy","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2022.01.031_bib7","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1111\/j.1525-1470.2008.00768.x","article-title":"Methicillin-resistant Staphylococcus aureus colonization in children with atopic dermatitis","volume":"25","author":"Suh","year":"2008","journal-title":"Pediatr Dermatol"},{"key":"10.1016\/j.jaci.2022.01.031_bib8","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1046\/j.1365-4362.1997.00290.x","article-title":"Skin colonization of Staphylococcus aureus in atopic dermatitis patients seen at the National Skin Centre, Singapore","volume":"36","author":"Goh","year":"1997","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.jaci.2022.01.031_bib9","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1111\/bjd.14566","article-title":"Prevalence and odds of Staphylococcus aureus carriage in atopic dermatitis: a systematic review and meta-analysis","volume":"175","author":"Totte","year":"2016","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2022.01.031_bib10","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1128\/CMR.00104-12","article-title":"Staphylococcal and streptococcal superantigen exotoxins","volume":"26","author":"Spaulding","year":"2013","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.jaci.2022.01.031_bib11","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.tim.2017.11.008","article-title":"Staphylococcus aureus and atopic dermatitis: a complex and evolving relationship","volume":"26","author":"Geoghegan","year":"2018","journal-title":"Trends Microbiol"},{"key":"10.1016\/j.jaci.2022.01.031_bib12","first-page":"1365","article-title":"Microbiome of affected and unaffected skin of patients with atopic dermatitis before and after emollient treatment","volume":"13","author":"Seite","year":"2014","journal-title":"J Drugs Dermatol"},{"key":"10.1016\/j.jaci.2022.01.031_bib13","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1101\/gr.131029.111","article-title":"Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis","volume":"22","author":"Kong","year":"2012","journal-title":"Genome Res"},{"issue":"10","key":"10.1016\/j.jaci.2022.01.031_bib14","first-page":"CD003871","article-title":"Interventions to reduce Staphylococcus aureus in the management of eczema","volume":"2019","author":"George","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jaci.2022.01.031_bib15","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.anai.2017.08.289","article-title":"Efficacy of bleach baths in reducing severity of atopic dermatitis: a systematic review and meta-analysis","volume":"119","author":"Chopra","year":"2017","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaci.2022.01.031_bib16","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/j.1365-2230.2004.01679.x","article-title":"Staphylococcus aureus re-colonization in atopic dermatitis: beyond the skin","volume":"30","author":"Gilani","year":"2005","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.jaci.2022.01.031_bib17","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1001\/archdermatol.2010.129","article-title":"Staphylococcus aureus carriage in the anterior nares of close contacts of patients with atopic dermatitis","volume":"146","author":"Chiu","year":"2010","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaci.2022.01.031_bib18","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1111\/j.1365-2133.2009.09038.x","article-title":"Prevalence and molecular characteristics of Staphylococcus aureus isolates colonizing patients with atopic dermatitis and their close contacts in Singapore","volume":"160","author":"Chiu","year":"2009","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2022.01.031_bib19","doi-asserted-by":"crossref","first-page":"e581","DOI":"10.1111\/apa.13179","article-title":"Methicillin-resistant Staphylococcus aureus eradication in young infants should include the diaper area and treat housing contacts","volume":"104","author":"Meyer Sauteur","year":"2015","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.jaci.2022.01.031_bib20","doi-asserted-by":"crossref","first-page":"11971","DOI":"10.1073\/pnas.1002601107","article-title":"Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns","volume":"107","author":"Dominguez-Bello","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jaci.2022.01.031_bib21","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.00458","article-title":"Cohabiting family members share microbiota with one another and with their dogs","volume":"2","author":"Song","year":"2013","journal-title":"Elife"},{"key":"10.1016\/j.jaci.2022.01.031_bib22","doi-asserted-by":"crossref","DOI":"10.1128\/mSystems.00043-17","article-title":"The skin microbiome of cohabiting couples","volume":"2","author":"Ross","year":"2017","journal-title":"mSystems"},{"issue":"Suppl\u00a092","key":"10.1016\/j.jaci.2022.01.031_bib23","doi-asserted-by":"crossref","first-page":"44","DOI":"10.2340\/00015555924447","article-title":"Diagnostic features of atopic dermatitis","volume":"60","author":"Hanifin","year":"1980","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"10.1016\/j.jaci.2022.01.031_bib24","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1159\/000245677","article-title":"Clinical validation and guidelines for the SCORAD index: consensus report of the European Task Force on Atopic Dermatitis","volume":"195","author":"Kunz","year":"1997","journal-title":"Dermatology"},{"key":"10.1016\/j.jaci.2022.01.031_bib25","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1159\/000247298","article-title":"Severity scoring of atopic dermatitis: the SCORAD index. Consensus Report of the European Task Force on Atopic Dermatitis","volume":"186","year":"1993","journal-title":"Dermatology"},{"key":"10.1016\/j.jaci.2022.01.031_bib26","doi-asserted-by":"crossref","first-page":"16106","DOI":"10.1038\/nmicrobiol.2016.106","article-title":"Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare","volume":"1","author":"Chng","year":"2016","journal-title":"Nat Microbiol"},{"key":"10.1016\/j.jaci.2022.01.031_bib27","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/nbt.3820","article-title":"Nextflow enables reproducible computational workflows","volume":"35","author":"Di Tommaso","year":"2017","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.jaci.2022.01.031_bib28","doi-asserted-by":"crossref","first-page":"i884","DOI":"10.1093\/bioinformatics\/bty560","article-title":"fastp: an ultra-fast all-in-one FASTQ preprocessor","volume":"34","author":"Chen","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaci.2022.01.031_bib29","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1093\/bioinformatics\/btp698","article-title":"Fast and accurate long-read alignment with Burrows-Wheeler transform","volume":"26","author":"Li","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaci.2022.01.031_bib30","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1093\/bioinformatics\/btp352","article-title":"The Sequence Alignment\/Map format and SAMtools","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaci.2022.01.031_bib31","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1186\/s13059-019-1891-0","article-title":"Improved metagenomic analysis with Kraken 2","volume":"20","author":"Wood","year":"2019","journal-title":"Genome Biol"},{"key":"10.1016\/j.jaci.2022.01.031_bib32","doi-asserted-by":"crossref","first-page":"e104","DOI":"10.7717\/peerj-cs.104","article-title":"Bracken: estimating species abundance in metagenomics data","volume":"3","author":"Lu","year":"2017","journal-title":"PeerJ Comp Sci"},{"key":"10.1016\/j.jaci.2022.01.031_bib33","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1038\/s41564-018-0202-y","article-title":"Recognizing the reagent microbiome","volume":"3","author":"de Goffau","year":"2018","journal-title":"Nat Microbiol"},{"key":"10.1016\/j.jaci.2022.01.031_bib34","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.fsigen.2019.06.017","article-title":"Forensic characterization and statistical considerations of the CaDNAP 13-STR panel in 1,184 domestic dogs from Germany, Austria, and Switzerland","volume":"42","author":"Berger","year":"2019","journal-title":"Forensic Sci Int Genet"},{"key":"10.1016\/j.jaci.2022.01.031_bib35","doi-asserted-by":"crossref","DOI":"10.1128\/msystems.00053-18","article-title":"Balances: a new perspective for microbiome analysis","volume":"3","author":"Rivera-Pinto","year":"2018","journal-title":"mSystems"},{"key":"10.1016\/j.jaci.2022.01.031_bib36","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1023\/A:1024068626366","article-title":"Inference for the generalization error","volume":"52","author":"Nadeau","year":"2003","journal-title":"Machine Learning"},{"key":"10.1016\/j.jaci.2022.01.031_bib37","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/s41592-019-0431-x","article-title":"FEAST: fast expectation-maximization for microbial source tracking","volume":"16","author":"Shenhav","year":"2019","journal-title":"Nat Methods"},{"key":"10.1016\/j.jaci.2022.01.031_bib38","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s12966-019-0810-9","article-title":"Prominent positioning and food swaps are effective interventions to\u00a0reduce the saturated fat content of the shopping basket in an experimental online\u00a0supermarket: a randomized controlled trial","volume":"16","author":"Koutoukidis","year":"2019","journal-title":"Int J Behav Nutr Phys Act"},{"key":"10.1016\/j.jaci.2022.01.031_bib39","doi-asserted-by":"crossref","first-page":"5114","DOI":"10.1038\/s41467-018-07641-9","article-title":"High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries","volume":"9","author":"Jain","year":"2018","journal-title":"Nat Commun"},{"key":"10.1016\/j.jaci.2022.01.031_bib40","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/s41591-020-0894-4","article-title":"Cartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environment","volume":"26","author":"Chng","year":"2020","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2022.01.031_bib41","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1038\/s41467-017-02018-w","article-title":"Strain-resolved analysis of hospital rooms and infants reveals overlap between the human and room microbiome","volume":"8","author":"Brooks","year":"2017","journal-title":"Nat Commun"},{"key":"10.1016\/j.jaci.2022.01.031_bib42","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1186\/s13059-014-0524-x","article-title":"The Harvest suite for rapid core-genome alignment and visualization of thousands of intraspecific microbial genomes","volume":"15","author":"Treangen","year":"2014","journal-title":"Genome Biol"},{"key":"10.1016\/j.jaci.2022.01.031_bib43","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1007\/s00018-010-0389-4","article-title":"Mobile genetic elements of Staphylococcus aureus","volume":"67","author":"Malachowa","year":"2010","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.jaci.2022.01.031_bib44","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s13073-014-0090-6","article-title":"SRST2: rapid genomic surveillance for public health and hospital microbiology labs","volume":"6","author":"Inouye","year":"2014","journal-title":"Genome Med"},{"key":"10.1016\/j.jaci.2022.01.031_bib45","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1093\/jac\/dkw184","article-title":"Benchmarking of methods for identification of antimicrobial resistance genes in bacterial whole genome data","volume":"71","author":"Clausen","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jaci.2022.01.031_bib46","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1038\/nmeth.2658","article-title":"Differential abundance analysis for microbial marker-gene surveys","volume":"10","author":"Paulson","year":"2013","journal-title":"Nat Methods"},{"key":"10.1016\/j.jaci.2022.01.031_bib47","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aat8329","article-title":"Quorum sensing between bacterial species on the skin protects against epidermal injury in atopic dermatitis","volume":"11","author":"Williams","year":"2019","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jaci.2022.01.031_bib48","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1038\/ismej.2013.10","article-title":"Robust estimation of microbial diversity in theory and in practice","volume":"7","author":"Haegeman","year":"2013","journal-title":"ISME J"},{"key":"10.1016\/j.jaci.2022.01.031_bib49","doi-asserted-by":"crossref","first-page":"R60","DOI":"10.1186\/gb-2011-12-6-r60","article-title":"Metagenomic biomarker discovery and explanation","volume":"12","author":"Segata","year":"2011","journal-title":"Genome Biol"},{"key":"10.1016\/j.jaci.2022.01.031_bib50","doi-asserted-by":"crossref","first-page":"4703","DOI":"10.1038\/s41467-019-12253-y","article-title":"Microbe\u2013host interplay in atopic dermatitis and psoriasis","volume":"10","author":"Fyhrquist","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.jaci.2022.01.031_bib51","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1111\/all.14606","article-title":"Microbial and transcriptional differences elucidate atopic dermatitis heterogeneity across skin sites","volume":"76","author":"Ottman","year":"2021","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2022.01.031_bib52","doi-asserted-by":"crossref","DOI":"10.1128\/mSystems.00293-19","article-title":"A microbiome-based index for assessing skin health and treatment effects for atopic dermatitis in children","volume":"4","author":"Sun","year":"2019","journal-title":"mSystems"},{"key":"10.1016\/j.jaci.2022.01.031_bib53","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aah4680","article-title":"Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis","volume":"9","author":"Nakatsuji","year":"2017","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jaci.2022.01.031_bib54","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s40168-018-0412-9","article-title":"Individual and household attributes influence the dynamics of the personal skin microbiota and its association network","volume":"6","author":"Leung","year":"2018","journal-title":"Microbiome"},{"key":"10.1016\/j.jaci.2022.01.031_bib55","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1111\/pde.13829","article-title":"Variation of cultured skin microbiota in mothers and their infants during the first year postpartum","volume":"36","author":"Gaitanis","year":"2019","journal-title":"Pediatr Dermatol"},{"key":"10.1016\/j.jaci.2022.01.031_bib56","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/nature11209","article-title":"A framework for human microbiome research","volume":"486","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.jaci.2022.01.031_bib57","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/j.cell.2016.04.008","article-title":"Temporal stability of the human skin microbiome","volume":"165","author":"Oh","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.jaci.2022.01.031_bib58","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0151990","article-title":"Body site is a more determinant factor than human population diversity in the healthy skin microbiome","volume":"11","author":"Perez Perez","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jaci.2022.01.031_bib59","doi-asserted-by":"crossref","first-page":"e1252","DOI":"10.1542\/peds.2011-2308","article-title":"Relationship between maternal and neonatal Staphylococcus aureus colonization","volume":"129","author":"Jimenez-Truque","year":"2012","journal-title":"Pediatrics"},{"key":"10.1016\/j.jaci.2022.01.031_bib60","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/1471-2334-12-45","article-title":"Increased prevalence of methicillin-resistant Staphylococcus aureus nasal colonization in household contacts of children with community acquired disease","volume":"12","author":"Rafee","year":"2012","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.jaci.2022.01.031_bib61","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0049900","article-title":"Environmental contamination as a risk factor for intra-household Staphylococcus aureus transmission","volume":"7","author":"Knox","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jaci.2022.01.031_bib62","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/S0140-6736(06)68231-7","article-title":"Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus","volume":"367","author":"Diep","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.jaci.2022.01.031_bib63","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1128\/JCM.00387-14","article-title":"Detection and measurement of staphylococcal enterotoxin-like K (SEl-K) secretion by Staphylococcus aureus clinical isolates","volume":"52","author":"Aguilar","year":"2014","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jaci.2022.01.031_bib64","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1111\/jam.13462","article-title":"Biological characteristics of staphylococcal enterotoxin Q and its potential risk for food poisoning","volume":"122","author":"Hu","year":"2017","journal-title":"J Appl Microbiol"},{"key":"10.1016\/j.jaci.2022.01.031_bib65","doi-asserted-by":"crossref","first-page":"e00616","DOI":"10.1128\/mSphere.00616-19","article-title":"Staphylococcal virulence factors on the skin of atopic dermatitis patients","volume":"4","author":"Moran","year":"2019","journal-title":"mSphere"},{"key":"10.1016\/j.jaci.2022.01.031_bib66","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1128\/IAI.69.1.360-366.2001","article-title":"Biochemical and\u00a0biological properties of staphylococcal enterotoxin K","volume":"69","author":"Orwin","year":"2001","journal-title":"Infect Immun"},{"key":"10.1016\/j.jaci.2022.01.031_bib67","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/314654","article-title":"Staphylococcus aureus clinical isolates: antibiotic susceptibility, molecular characteristics, and ability to form biofilm","volume":"2013","author":"Indrawattana","year":"2013","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.jaci.2022.01.031_bib68","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0028276","article-title":"Genotypes and toxin gene profiles of Staphylococcus aureus clinical isolates from China","volume":"6","author":"Xie","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jaci.2022.01.031_bib69","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1128\/CMR.00049-15","article-title":"Decolonization in prevention of health care\u2013associated infections","volume":"29","author":"Septimus","year":"2016","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.jaci.2022.01.031_bib70","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1177\/1099800416654013","article-title":"Chlorhexidine bathing effects on health-care\u2013associated infections","volume":"19","author":"Denny","year":"2017","journal-title":"Biol Res Nurs"},{"key":"10.1016\/j.jaci.2022.01.031_bib71","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1093\/cid\/cir034","article-title":"Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children: executive summary","volume":"52","author":"Liu","year":"2011","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jaci.2022.01.031_bib72","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1097\/DCC.0000000000000192","article-title":"Effectiveness of decolonization with chlorhexidine and mupirocin in reducing surgical site infections: a systematic review","volume":"35","author":"George","year":"2016","journal-title":"Dimens Crit Care Nurs"},{"key":"10.1016\/j.jaci.2022.01.031_bib73","doi-asserted-by":"crossref","first-page":"S269","DOI":"10.1016\/j.ajic.2014.05.011","article-title":"Impact of\u00a0detection, education, research and decolonization without isolation in long-term care (DERAIL) on methicillin-resistant Staphylococcus aureus colonization and transmission at 3 long-term care facilities","volume":"42","author":"Schora","year":"2014","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jaci.2022.01.031_bib74","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/1471-2369-14-93","article-title":"Persistent nasal methicillin-resistant Staphylococcus aureus carriage in hemodialysis outpatients: a predictor of worse outcome","volume":"14","author":"Schmid","year":"2013","journal-title":"BMC Nephrol"},{"key":"10.1016\/j.jaci.2022.01.031_bib75","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.ajic.2016.02.008","article-title":"Universal decolonization with hypochlorous solution in a burn intensive care unit in a tertiary care community hospital","volume":"44","author":"Gray","year":"2016","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jaci.2022.01.031_bib76","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/j.1365-2133.1976.tb07021.x","article-title":"Co-operative double-blind trial of an antibiotic\/corticoid combination in impetiginized atopic dermatitis","volume":"95","author":"Wachs","year":"1976","journal-title":"Br J Dermatol"},{"issue":"suppl\u00a01","key":"10.1016\/j.jaci.2022.01.031_bib77","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1159\/000089196","article-title":"The importance of bacterial superantigens produced by Staphylococcus aureus in the treatment of atopic dermatitis using povidone\u2013iodine","volume":"212","author":"Sugimoto","year":"2006","journal-title":"Dermatology"},{"key":"10.1016\/j.jaci.2022.01.031_bib78","article-title":"Interventions to reduce Staphylococcus aureus in the management of atopic eczema","volume":"3","author":"Birnie","year":"2008","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jaci.2022.01.031_bib79","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/j.1365-2133.2010.10078.x","article-title":"Interventions to reduce Staphylococcus aureus in the management of atopic eczema: an updated Cochrane review","volume":"164","author":"Bath-Hextall","year":"2011","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2022.01.031_bib80","doi-asserted-by":"crossref","first-page":"e808","DOI":"10.1542\/peds.2008-2217","article-title":"Treatment of Staphylococcus aureus colonization in atopic dermatitis decreases disease severity","volume":"123","author":"Huang","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.jaci.2022.01.031_bib81","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1111\/j.1365-2133.2006.07410.x","article-title":"Skin colonization by Staphylococcus aureus in patients with eczema and atopic dermatitis and relevant combined topical therapy: a double-blind multicentre randomized controlled trial","volume":"155","author":"Gong","year":"2006","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaci.2022.01.031_bib82","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s40257-020-00538-8","article-title":"The role of the microbiome and microbiome-derived metabolites in atopic dermatitis and non-histaminergic itch","volume":"21","author":"Li","year":"2020","journal-title":"Am J Clin Dermatol"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674922003451?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674922003451?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T15:04:07Z","timestamp":1777475047000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674922003451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":82,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S0091674922003451"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2022.01.031","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Shared signatures and divergence in skin microbiomes of children with atopic dermatitis and their caregivers","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2022.01.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}