{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T06:33:50Z","timestamp":1793255630002,"version":"4.5.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"am","delay-in-days":370,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100006259","name":"Teva Pharmaceutical Industries","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006259","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015166","name":"UPMC","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI106684"],"award-info":[{"award-number":["AI106684"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI048927"],"award-info":[{"award-number":["AI048927"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["F32 HL137089"],"award-info":[{"award-number":["F32 HL137089"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL113956"],"award-info":[{"award-number":["HL113956"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.jaci.2023.02.028","type":"journal-article","created":{"date-parts":[[2023,3,7]],"date-time":"2023-03-07T20:27:23Z","timestamp":1678220843000},"page":"94-106.e12","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":63,"title":["CCL5 is a potential bridge between type 1 and type 2 inflammation in asthma"],"prefix":"10.1016","volume":"152","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5037-2804","authenticated-orcid":false,"given":"Marc","family":"Gauthier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sagar Laxman","family":"Kale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy B.","family":"Oriss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Gorry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard P.","family":"Ramonell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn","family":"Dalton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabir","family":"Ray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John V.","family":"Fahy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max A.","family":"Seibold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nizar","family":"Jarjour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Gaston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene R.","family":"Bleecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah A.","family":"Meyers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette T.","family":"Hastie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elliot","family":"Israel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce D.","family":"Levy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Mauger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serpil","family":"Erzurum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzy A.","family":"Comhair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally E.","family":"Wenzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anuradha","family":"Ray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2023.02.028_bib1","doi-asserted-by":"crossref","first-page":"880","DOI":"10.2105\/AJPH.2004.050039","article-title":"Asthma prevalence among US adults, 1998-2000: role of Puerto Rican ethnicity and behavioral and geographic factors","volume":"96","author":"Rose","year":"2006","journal-title":"Am J Public Health"},{"key":"10.1016\/j.jaci.2023.02.028_bib2","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.jaci.2014.08.042","article-title":"The prevalence of severe refractory asthma","volume":"135","author":"Hekking","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib3","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1164\/rccm.201504-0763PP","article-title":"Evolving concepts of asthma","volume":"192","author":"Gauthier","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2023.02.028_bib4","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1111\/j.1365-2222.2011.03929.x","article-title":"Severe asthma: from characteristics to phenotypes to endotypes","volume":"42","author":"Wenzel","year":"2012","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2023.02.028_bib5","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1056\/NEJMra2032506","article-title":"Biologic therapies for severe asthma","volume":"386","author":"Brusselle","year":"2022","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2023.02.028_bib6","doi-asserted-by":"crossref","first-page":"3037","DOI":"10.1172\/JCI80911","article-title":"High IFN-gamma and low SLPI mark severe asthma in mice and humans","volume":"125","author":"Raundhal","year":"2015","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2023.02.028_bib7","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.94580","article-title":"Severe asthma in humans and mouse model suggests a CXCL10 signature underlies corticosteroid-resistant Th1 bias","volume":"2","author":"Gauthier","year":"2017","journal-title":"JCI Insight"},{"key":"10.1016\/j.jaci.2023.02.028_bib8","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.91019","article-title":"IRF5 distinguishes severe asthma in humans and drives Th1 phenotype and airway hyperreactivity in mice","volume":"2","author":"Oriss","year":"2017","journal-title":"JCI Insight"},{"key":"10.1016\/j.jaci.2023.02.028_bib9","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jaci.2021.05.044","article-title":"Dual role for CXCR3 and CCR5 in asthmatic type 1 inflammation","volume":"149","author":"Gauthier","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib10","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1164\/rccm.201607-1407OC","article-title":"Gene expression correlated with severe asthma characteristics reveals heterogeneous mechanisms of severe disease","volume":"195","author":"Modena","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2023.02.028_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.108974","article-title":"High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status","volume":"35","author":"Camiolo","year":"2021","journal-title":"Cell Rep"},{"key":"10.1016\/j.jaci.2023.02.028_bib12","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1164\/ajrccm.153.4.8616572","article-title":"Increased MCP-1, RANTES, and MIP-1alpha in bronchoalveolar lavage fluid of allergic asthmatic patients","volume":"153","author":"Alam","year":"1996","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2023.02.028_bib13","doi-asserted-by":"crossref","first-page":"2892","DOI":"10.1002\/eji.1830271122","article-title":"The CC chemokine antagonist Met-RANTES inhibits eosinophil effector functions through the chemokine receptors CCR1 and CCR3","volume":"27","author":"Elsner","year":"1997","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib14","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.jaci.2014.01.029","article-title":"Effects of rhinovirus species on viral replication and cytokine production","volume":"134","author":"Nakagome","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib15","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1002\/eji.200323930","article-title":"Respiratory syncytial virus\u2013induced CCL5\/RANTES contributes to exacerbation of allergic airway inflammation","volume":"33","author":"John","year":"2003","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib16","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1172\/JCI1422","article-title":"The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions","volume":"101","author":"Qin","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2023.02.028_bib17","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1183\/09031936.00202013","article-title":"International ERS\/ATS guidelines on definition, evaluation and treatment of severe asthma","volume":"43","author":"Chung","year":"2014","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaci.2023.02.028_bib18","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1186\/1471-2105-15-182","article-title":"Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads","volume":"15","author":"Jiang","year":"2014","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.jaci.2023.02.028_bib19","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.3317","article-title":"HISAT: a fast spliced aligner with low memory requirements","volume":"12","author":"Kim","year":"2015","journal-title":"Nat Methods"},{"key":"10.1016\/j.jaci.2023.02.028_bib20","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1093\/bioinformatics\/btu638","article-title":"HTSeq\u2014a Python framework to work with high-throughput sequencing data","volume":"31","author":"Anders","year":"2015","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaci.2023.02.028_bib21","doi-asserted-by":"crossref","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol"},{"key":"10.1016\/j.jaci.2023.02.028_bib22","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1016\/j.jaci.2013.11.042","article-title":"Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data","volume":"133","author":"Wu","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib23","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1016\/j.jaip.2022.03.019","article-title":"Characterization of asthma by age of onset: a multi-database cohort study","volume":"10","author":"Baan","year":"2022","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2023.02.028_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2021.103163","article-title":"Regulated on activation, normal T cell expressed and secreted (RANTES) drives the resolution of allergic asthma","volume":"24","author":"Li","year":"2021","journal-title":"iScience"},{"key":"10.1016\/j.jaci.2023.02.028_bib25","doi-asserted-by":"crossref","first-page":"L658","DOI":"10.1152\/ajplung.2000.279.4.L658","article-title":"Inducible lung-specific expression of RANTES: preferential recruitment of neutrophils","volume":"279","author":"Pan","year":"2000","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1016\/j.jaci.2023.02.028_bib26","doi-asserted-by":"crossref","first-page":"474","DOI":"10.4049\/jimmunol.162.1.474","article-title":"Up-regulation of CCR1 and CCR3 and induction of chemotaxis to CC chemokines by IFN-\u03b3 in human neutrophils","volume":"162","author":"Bonecchi","year":"1999","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib27","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1183\/09031936.99.13612609","article-title":"CD69 surface expression on human lung eosinophils after segmental allergen provocation","volume":"13","author":"Julius","year":"1999","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaci.2023.02.028_bib28","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1002\/eji.201646837","article-title":"CD69: from activation marker to metabolic gatekeeper","volume":"47","author":"Cibri\u00e1n","year":"2017","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib29","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aas9673","article-title":"Location, location, location: tissue resident memory T cells in mice and humans","volume":"4","author":"Szabo","year":"2019","journal-title":"Sci Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib30","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.4049\/jimmunol.1700257","article-title":"Biased generation and in situ activation of lung tissue\u2013resident memory CD4 T cells in the pathogenesis of allergic asthma","volume":"200","author":"Turner","year":"2018","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib31","doi-asserted-by":"crossref","first-page":"L348","DOI":"10.1152\/ajplung.00099.2015","article-title":"IFN-gamma\u2013induced JAK\/STAT, but not NF-kappaB, signaling pathway is insensitive to glucocorticoid in airway epithelial cells","volume":"309","author":"O\u2019Connell","year":"2015","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"9","key":"10.1016\/j.jaci.2023.02.028_bib32","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aam5446","article-title":"Natural killer cell\u2013mediated inflammation resolution is disabled in severe asthma","volume":"2","author":"Duvall","year":"2017","journal-title":"Sci Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib33","doi-asserted-by":"crossref","first-page":"2048","DOI":"10.1016\/j.jaci.2017.08.020","article-title":"TH1 signatures are present in the lower airways of children with severe asthma, regardless of allergic status","volume":"141","author":"Wisniewski","year":"2018","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib34","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.jaci.2020.03.037","article-title":"Human TH1 and TH2 cells targeting rhinovirus and allergen coordinately promote allergic asthma","volume":"146","author":"Muehling","year":"2020","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib35","doi-asserted-by":"crossref","first-page":"3140","DOI":"10.1038\/s41467-022-30615-x","article-title":"Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis","volume":"13","author":"Damsky","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.jaci.2023.02.028_bib36","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.autrev.2013.10.010","article-title":"Chemokine (C-X-C motif) ligand (CXCL)10 in autoimmune diseases","volume":"13","author":"Antonelli","year":"2014","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jaci.2023.02.028_bib37","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1164\/rccm.200409-1220OC","article-title":"The CXCL10\/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle","volume":"171","author":"Brightling","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2023.02.028_bib38","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1067\/mai.2001.113524","article-title":"Expression of IFN-gamma\u2013inducible protein; monocyte chemotactic proteins 1, 3, and 4; and eotaxin in TH1- and TH2-mediated lung diseases","volume":"107","author":"Miotto","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib39","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.autrev.2008.07.017","article-title":"Immunopathogenesis of HCV-related endocrine manifestations in chronic hepatitis and mixed cryoglobulinemia","volume":"8","author":"Antonelli","year":"2008","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jaci.2023.02.028_bib40","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S1074-7613(00)80533-6","article-title":"Cytokines induce the development of functionally heterogeneous T helper cell subsets","volume":"8","author":"O\u2019Garra","year":"1998","journal-title":"Immunity"},{"key":"10.1016\/j.jaci.2023.02.028_bib41","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1164\/ajrccm.156.5.9610064","article-title":"Release of RANTES, MIP-1\u03b1, and MCP-1 into asthmatic airways following endobronchial allergen challenge","volume":"156","author":"Holgate","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2023.02.028_bib42","doi-asserted-by":"crossref","first-page":"165","DOI":"10.4049\/jimmunol.163.1.165","article-title":"Differential expression and cross-regulatory function of RANTES during mycobacterial (type 1) and schistosomal (type 2) antigen-elicited granulomatous inflammation","volume":"163","author":"Chensue","year":"1999","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib43","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aaw8718","article-title":"The human tissue\u2013resident CCR5+ T cell compartment maintains protective and functional properties during inflammation","volume":"11","author":"Woodward Davis","year":"2019","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jaci.2023.02.028_bib44","doi-asserted-by":"crossref","first-page":"5498","DOI":"10.4049\/jimmunol.171.10.5498","article-title":"Inhibition of airway inflammation by amino-terminally modified RANTES\/CC chemokine ligand 5 analogues is not mediated through CCR3","volume":"171","author":"Chvatchko","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib45","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.4049\/jimmunol.157.4.1806","article-title":"Eosinophil recruitment following allergen challenge is associated with the release of the chemokine RANTES into asthmatic airways","volume":"157","author":"Teran","year":"1996","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib46","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1182\/blood.V94.1.23.413k13_23_32","article-title":"Rapid mobilization of intracellularly stored RANTES in response to interferon-\u03b3 in human eosinophils","volume":"94","author":"Lacy","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.jaci.2023.02.028_bib47","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1046\/j.1365-2249.1999.01068.x","article-title":"Role of JAK2 signal transductional pathway in activation and survival of human peripheral eosinophils by interferon-gamma (IFN-\u03b3)","volume":"118","author":"Ochiai","year":"2001","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib48","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1016\/j.jaip.2018.12.027","article-title":"Lung lavage granulocyte patterns and clinical phenotypes in children with severe, therapy-resistant asthma","volume":"7","author":"Teague","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2023.02.028_bib49","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jaci.2012.02.010","article-title":"Determinants of asthma after severe respiratory syncytial virus bronchiolitis","volume":"130","author":"Bacharier","year":"2012","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.02.028_bib50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12985-022-01805-2","article-title":"Comparison of immune response to human rhinovirus C and respiratory syncytial virus in highly differentiated human airway epithelial cells","volume":"19","author":"Yuan","year":"2022","journal-title":"Virol J"},{"key":"10.1016\/j.jaci.2023.02.028_bib51","doi-asserted-by":"crossref","first-page":"4236","DOI":"10.1016\/j.celrep.2019.11.103","article-title":"Bystander activation of pulmonary Trm cells attenuates the severity of bacterial pneumonia by enhancing neutrophil recruitment","volume":"29","author":"Ge","year":"2019","journal-title":"Cell Rep"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674923002890?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674923002890?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T04:47:17Z","timestamp":1762231637000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674923002890"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["S0091674923002890"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2023.02.028","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CCL5 is a potential bridge between type 1 and type 2 inflammation in asthma","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2023.02.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}