{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:44:23Z","timestamp":1787067863365,"version":"build-2736575974"},"reference-count":56,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T00:00:00Z","timestamp":1717545600000},"content-version":"am","delay-in-days":370,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.jaci.2023.03.015","type":"journal-article","created":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T12:20:08Z","timestamp":1679660408000},"page":"1448-1456","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Mechanistic and clinical updates in AERD: 2021-2022"],"prefix":"10.1016","volume":"151","author":[{"given":"Whitney W.","family":"Stevens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8549-1835","authenticated-orcid":false,"given":"Katherine N.","family":"Cahill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2023.03.015_bib1","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1016\/j.jaci.2013.12.1092","article-title":"Basophils are elevated in nasal polyps of patients with chronic rhinosinusitis without aspirin sensitivity","volume":"133","author":"Mahdavinia","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2021.02.045","article-title":"Studies of the role of basophils in aspirin-exacerbated respiratory disease pathogenesis","volume":"148","author":"Stevens","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib3","doi-asserted-by":"crossref","first-page":"eabb7221","DOI":"10.1126\/sciimmunol.abb7221","article-title":"Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation","volume":"6","author":"Dwyer","year":"2021","journal-title":"Sci Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib4","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.jaci.2020.04.064","article-title":"Inflammatory macrophage memory in nonsteroidal anti-inflammatory drug-exacerbated respiratory disease","volume":"147","author":"Haimerl","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib5","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.jaci.2022.08.021","article-title":"Updates on immune mechanisms in aspirin-exacerbated respiratory disease","volume":"151","author":"Laidlaw","year":"2023","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib6","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/j.jaci.2020.08.007","article-title":"Heterogeneity of lower airway inflammation in patients with NSAID-exacerbated respiratory disease","volume":"147","author":"Jakiela","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib7","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.jaci.2020.04.031","article-title":"Activation of the 15-lipoxygenase pathway in aspirin-exacerbated respiratory disease","volume":"147","author":"Stevens","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib8","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.jaci.2020.10.041","article-title":"Leukotriene D(4) paradoxically limits LTC(4)-driven platelet activation and lung immunopathology","volume":"148","author":"Liu","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2019.06.037","article-title":"15-Lipoxygenase 1 in nasal polyps promotes CCL26\/eotaxin 3 expression through extracellular signal-regulated kinase activation","volume":"144","author":"Li","year":"2019","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib10","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/s41588-018-0314-6","article-title":"A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis","volume":"51","author":"Kristjansson","year":"2019","journal-title":"Nat Genet"},{"key":"10.1016\/j.jaci.2023.03.015_bib11","doi-asserted-by":"crossref","DOI":"10.1172\/JCI151685","article-title":"15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation","volume":"132","author":"Nagasaki","year":"2022","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2023.03.015_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2017.09.044","article-title":"PEBP1 Wardens ferroptosis by enabling lipoxygenase generation of lipid death signals","volume":"171","author":"Wenzel","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.jaci.2023.03.015_bib13","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.jaci.2020.01.027","article-title":"Formation of nasal polyps: The roles of innate type 2 inflammation and deposition of fibrin","volume":"145","author":"Takabayashi","year":"2020","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2022.05.021","article-title":"Retinoic acid promotes fibrinolysis and may regulate polyp formation","volume":"150","author":"Sakashita","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib15","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1111\/all.15074","article-title":"Endotypes of chronic rhinosinusitis: relationships to disease phenotypes, pathogenesis, clinical findings, and treatment approaches","volume":"77","author":"Kato","year":"2022","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2023.03.015_bib16","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.jaci.2022.10.010","article-title":"Endotypes of chronic rhinosinusitis based on inflammatory and remodeling factors","volume":"151","author":"Wang","year":"2023","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib17","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1111\/all.12644","article-title":"Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC Study","volume":"70","author":"Tokunaga","year":"2015","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2023.03.015_bib18","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.jaci.2021.03.024","article-title":"Rethinking neutrophils and eosinophils in chronic rhinosinusitis","volume":"148","author":"Delemarre","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaip.2019.05.009","article-title":"Associations between inflammatory endotypes and clinical presentations in chronic rhinosinusitis","volume":"7","author":"Stevens","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2023.03.015_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2015.12.1324","article-title":"Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers","volume":"137","author":"Tomassen","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2020.08.036","article-title":"A substantial neutrophilic inflammation as regular part of severe type 2 chronic rhinosinusitis with nasal polyps","volume":"147","author":"Delemarre","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib22","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/all.14071","article-title":"Neutrophils are underrecognized contributors to inflammatory burden and quality of life in chronic rhinosinusitis","volume":"75","author":"Succar","year":"2020","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2023.03.015_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2020.11.001","article-title":"Inflammatory heterogeneity in aspirin-exacerbated respiratory disease","volume":"147","author":"Scott","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib24","doi-asserted-by":"crossref","unstructured":"Jakiela B, Soja J, Sladek K, Przybyszowski M, Plutecka H, Gielicz A, et al. Bronchial epithelial cell transcriptome shows endotype heterogeneity of asthma in patients with NSAID-exacerbated respiratory disease [e-pub ahead of print]. J Allergy Clin Immunol https:\/\/doi.org\/10.1016\/j.jaci.2022.10.029. Accessed January 31, 2023.","DOI":"10.1016\/j.jaci.2022.10.029"},{"key":"10.1016\/j.jaci.2023.03.015_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaip.2022.03.021","article-title":"Utility of nasal mucus inflammatory profile as a biomarker of nasal polyp regrowth in aspirin-exacerbated respiratory disease","volume":"10","author":"Corey","year":"2022","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2023.03.015_bib26","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1002\/lary.26391","article-title":"Prevalence of polyp recurrence after endoscopic sinus surgery for chronic rhinosinusitis with nasal polyposis","volume":"127","author":"DeConde","year":"2017","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaci.2023.03.015_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2022.02.029","article-title":"Prognostic factors for polyp recurrence in chronic rhinosinusitis with nasal polyps","volume":"150","author":"Bai","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib28","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.jaci.2014.07.031","article-title":"Prostaglandin D: a dominant mediator of aspirin-exacerbated respiratory disease","volume":"135","author":"Cahill","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib29","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.jaci.2018.10.007","article-title":"Plasma tryptase elevation during aspirin-induced reactions in aspirin-exacerbated respiratory disease","volume":"143","author":"Cahill","year":"2019","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2021.12.787","article-title":"Mediator production and severity of aspirin-induced respiratory reactions: impact of sampling site and body mass index","volume":"150","author":"Cahill","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib31","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/S1081-1206(10)61101-5","article-title":"Effect of leukotriene modifier drugs on the safety of oral aspirin challenges","volume":"97","author":"White","year":"2006","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib32","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1016\/j.jaip.2019.02.037","article-title":"Sinus surgery improves lower respiratory tract reactivity during aspirin desensitization for AERD","volume":"7","author":"Huang","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2023.03.015_bib33","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1016\/j.jaip.2018.12.014","article-title":"Sinus surgery is associated with a decrease in aspirin-induced reaction severity in patients with aspirin exacerbated respiratory disease","volume":"7","author":"Jerschow","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2023.03.015_bib34","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1365-2362.2010.02371.x","article-title":"Body mass index is associated with leukotriene inflammation in asthmatics","volume":"41","author":"Giouleka","year":"2011","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.jaci.2023.03.015_bib35","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.jaci.2020.10.043","volume":"147","author":"Stevens","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib36","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/all.13599","article-title":"Diagnosis and management of NSAID-exacerbated respiratory disease (N-ERD)-a EAACI position paper","volume":"74","author":"Kowalski","year":"2019","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2023.03.015_bib37","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1111\/cea.13886","article-title":"Biomarkers for predicting response to aspirin therapy in aspirin-exacerbated respiratory disease","volume":"51","author":"Tyrak","year":"2021","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2023.03.015_bib38","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jaci.2021.06.009","article-title":"Immunologic effects of aspirin desensitization and high-dose aspirin therapy in aspirin-exacerbated respiratory disease","volume":"148","author":"Cahill","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib39","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.jaci.2021.05.043","article-title":"Mepolizumab targets multiple immune cells in aspirin-exacerbated respiratory disease","volume":"148","author":"Buchheit","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib40","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.jaci.2022.04.007","article-title":"Rapid and sustained effect of dupilumab on clinical and mechanistic outcomes in aspirin-exacerbated respiratory disease","volume":"150","author":"Buchheit","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib41","doi-asserted-by":"crossref","first-page":"E61","DOI":"10.1002\/lary.27564","article-title":"Dexpramipexole depletes blood and tissue eosinophils in nasal polyps with no change in polyp size","volume":"129","author":"Laidlaw","year":"2019","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaci.2023.03.015_bib42","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1016\/j.jaci.2020.02.035","article-title":"IL-5Ralpha marks nasal polyp IgG4- and IgE-expressing cells in aspirin-exacerbated respiratory disease","volume":"145","author":"Buchheit","year":"2020","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib43","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.jaip.2018.01.038","article-title":"A retrospective analysis of mepolizumab in subjects with aspirin-exacerbated respiratory disease","volume":"6","author":"Tuttle","year":"2018","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2023.03.015_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaip.2021.09.030","article-title":"Appraisal of the real-world effectiveness of biologic therapies in aspirin-exacerbated respiratory disease","volume":"10","author":"Wangberg","year":"2022","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2023.03.015_bib45","article-title":"Mepolizumab for chronic rhinosinusitis with nasal polyps: treatment efficacy by comorbidity and blood eosinophil count","volume":"149","author":"Bachert","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib46","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.jaip.2022.12.004","article-title":"Comorbidities modify the phenotype but not the treatment effectiveness to mepolizumab in severe eosinophilic asthma","volume":"11","author":"Kritikos","year":"2023","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2023.03.015_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaip.2019.03.044","article-title":"Dupilumab improves nasal polyp burden and asthma control in patients with CRSwNP and AERD","volume":"7","author":"Laidlaw","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2023.03.015_bib48","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1111\/all.15067","article-title":"Efficacy and safety of dupilumab in patients with uncontrolled severe chronic rhinosinusitis with nasal polyps and a clinical diagnosis of NSAID-ERD: Results from two randomized placebo-controlled phase 3 trials","volume":"77","author":"Mullol","year":"2022","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2023.03.015_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaip.2021.02.020","article-title":"Efficacy of dupilumab in patients with aspirin-exacerbated respiratory disease and previous inadequate response to anti-IL-5 or anti-IL-5Ralpha in a real-world setting","volume":"9","author":"Bavaro","year":"2021","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2023.03.015_bib50","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.jaci.2022.09.012","article-title":"Mechanisms by which dupilumab normalizes eicosanoid metabolism and restores aspirin-tolerance in AERD: A hypothesis","volume":"151","author":"Picado","year":"2023","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib51","doi-asserted-by":"crossref","first-page":"2201335","DOI":"10.1183\/13993003.01335-2022","article-title":"Dupilumab increases aspirin tolerance in NSAID-exacerbated respiratory disease (N-ERD)","volume":"61","author":"Schneider","year":"2023","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaci.2023.03.015_bib52","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1164\/rccm.201809-1755OC","article-title":"Unique Effect of Aspirin Therapy on Biomarkers in Aspirin-exacerbated Respiratory Disease. A\u00a0Prospective Trial","volume":"200","author":"Cahill","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2023.03.015_bib53","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1111\/cea.14158","article-title":"Efficacy of an oral CRTH2 antagonist (AZD1981) in the treatment of chronic rhinosinusitis with nasal polyps in adults: A\u00a0randomized controlled clinical trial","volume":"52","author":"Price","year":"2022","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2023.03.015_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2021.12.759","article-title":"Phase 3b\u00a0randomized controlled trial of fevipiprant in patients with nasal polyposis\u00a0with asthma (THUNDER)","volume":"149","author":"Gevaert","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib55","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1016\/j.jaci.2022.03.001","article-title":"Fevipiprant in CRSwNP and comorbid asthma: Wrong target population or wrong PGD(2) receptor?","volume":"149","author":"Cahill","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.03.015_bib56","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1164\/ajrccm.153.2.8564100","article-title":"Inhaled\u00a0PGE2 prevents aspirin-induced bronchoconstriction and urinary LTE4\u00a0excretion in aspirin-sensitive asthma","volume":"153","author":"Sestini","year":"1996","journal-title":"Am J Respir Crit Care Med"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674923003676?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674923003676?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T09:42:47Z","timestamp":1758793367000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674923003676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":56,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["S0091674923003676"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2023.03.015","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mechanistic and clinical updates in AERD: 2021-2022","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2023.03.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}