{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:10:25Z","timestamp":1790316625241,"version":"4.1.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100012542","name":"Sichuan Province Science and Technology Support Program","doi-asserted-by":"publisher","award":["23NSFSC4098"],"award-info":[{"award-number":["23NSFSC4098"]}],"id":[{"id":"10.13039\/100012542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["NMRC\/CIRG\/1458\/2016"],"award-info":[{"award-number":["NMRC\/CIRG\/1458\/2016"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2022M712270"],"award-info":[{"award-number":["2022M712270"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2023T160453"],"award-info":[{"award-number":["2023T160453"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004912","name":"Sichuan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013365","name":"Sichuan University West China Hospital","doi-asserted-by":"publisher","award":["YN20230783"],"award-info":[{"award-number":["YN20230783"]}],"id":[{"id":"10.13039\/501100013365","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.jaci.2023.09.020","type":"journal-article","created":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T21:20:22Z","timestamp":1695936022000},"page":"1444-1459.e14","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Hypoxia-inducible factor 1\u03b1 activates the NLRP3 inflammasome to regulate epithelial differentiation in chronic rhinosinusitis"],"prefix":"10.1016","volume":"152","author":[{"given":"Bing","family":"Zhong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silu","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai Sen","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsiao Hui","family":"Ong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jintao","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yafeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shixi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luo","family":"Ba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1783-0591","authenticated-orcid":false,"given":"Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"De Yun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2023.09.020_bib1","first-page":"205","article-title":"P-glycoprotein inhibition with verapamil overcomes mometasone resistance in chronic sinusitis with nasal polyps","volume":"59","author":"Taha","year":"2021","journal-title":"Rhinology"},{"key":"10.1016\/j.jaci.2023.09.020_bib2","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1002\/alr.21316","article-title":"P-glycoprotein promotes epithelial T helper 2\u2013associated cytokine secretion in chronic sinusitis with nasal polyps","volume":"4","author":"Bleier","year":"2014","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jaci.2023.09.020_bib3","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.jaci.2021.06.023","article-title":"Extrafollicular PD-1highCXCR5\u2212CD4+ T cells participate in local immunoglobulin production in nasal polyps","volume":"149","author":"Wang","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib4","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/j.jaci.2022.02.016","article-title":"Mechanisms and pathogenesis of chronic rhinosinusitis","volume":"149","author":"Kato","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib5","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.jaci.2014.08.031","article-title":"Increased noneosinophilic nasal polyps in chronic rhinosinusitis in US second-generation Asians suggest genetic regulation of eosinophilia","volume":"135","author":"Mahdavinia","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib6","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.jaci.2008.07.008","article-title":"Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease","volume":"122","author":"Zhang","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib7","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.jaci.2022.02.031","article-title":"IL-17A mediates pyroptosis via the ERK pathway and contributes to steroid resistance in CRSwNP","volume":"150","author":"Li","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib8","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/j.jaci.2022.02.026","article-title":"Lipid mediators are detectable in the nasal epithelium and differ by asthma status in female subjects","volume":"150","author":"Johnson","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib9","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1016\/j.jaci.2021.12.793","article-title":"Altered secretome by diesel exhaust particles and lipopolysaccharide in primary human nasal epithelium","volume":"149","author":"Kim","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib10","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.yexcr.2018.12.024","article-title":"uPA affects the CRSsNP nasal mucosa epithelium apoptosis by regulating WIF1","volume":"377","author":"Hu","year":"2019","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.jaci.2023.09.020_bib11","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00877-2020","article-title":"Age-dependent response of the human nasal epithelium to rhinovirus infection","volume":"56","author":"Usemann","year":"2020","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaci.2023.09.020_bib12","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1002\/ijc.29519","article-title":"HIF-1 at the crossroads of hypoxia, inflammation, and cancer","volume":"138","author":"Balamurugan","year":"2016","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jaci.2023.09.020_bib13","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/all.12064","article-title":"Features of airway remodeling in different types of Chinese chronic rhinosinusitis are associated with inflammation patterns","volume":"68","author":"Shi","year":"2013","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2023.09.020_bib14","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1164\/rccm.201109-1706OC","article-title":"Hypoxia-inducible factor 1 mediates nasal polypogenesis by inducing epithelial-to-mesenchymal transition","volume":"185","author":"Shin","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2023.09.020_bib15","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1165\/rcmb.2013-0237OC","article-title":"Submersion and hypoxia inhibit ciliated cell differentiation in a Notch-dependent manner","volume":"51","author":"Gerovac","year":"2014","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jaci.2023.09.020_bib16","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/path.2863","article-title":"Hypoxia-inducible factor-1 signalling promotes goblet cell hyperplasia in airway epithelium","volume":"224","author":"Polosukhin","year":"2011","journal-title":"J Pathol"},{"key":"10.1016\/j.jaci.2023.09.020_bib17","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/eji.201646554","article-title":"ASC and NLRP3 impair host defense during lethal pneumonia caused by serotype 3 Streptococcus pneumoniae in mice","volume":"48","author":"van Lieshout","year":"2018","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib18","doi-asserted-by":"crossref","first-page":"e01776","DOI":"10.1128\/JVI.01776-17","article-title":"Inflammasome antagonism by human parainfluenza virus type 3 C protein","volume":"92","author":"Shil","year":"2018","journal-title":"J Virol"},{"key":"10.1016\/j.jaci.2023.09.020_bib19","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/s41577-019-0165-0","article-title":"The NLRP3 inflammasome: molecular activation and regulation to therapeutics","volume":"19","author":"Swanson","year":"2019","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib20","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20190314","article-title":"Inflammasome signaling and regulation of interleukin-1 family cytokines","volume":"217","author":"Chan","year":"2020","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2023.09.020_bib21","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1164\/rccm.201905-1013OC","article-title":"Specific inhibition of the NLRP3 inflammasome as an antiinflammatory strategy in cystic fibrosis","volume":"200","author":"McElvaney","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2023.09.020_bib22","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.jaci.2019.05.006","article-title":"NOD-like receptor family, pyrin domain containing 3 (NLRP3) contributes to inflammation, pyroptosis, and mucin production in human airway epithelium on rhinovirus infection","volume":"144","author":"Liu","year":"2019","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib23","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1111\/all.14571","article-title":"Hypoxia-induced factor-1alpha induces NLRP3 expression by M1 macrophages in noneosinophilic chronic rhinosinusitis with nasal polyps","volume":"76","author":"Zhong","year":"2021","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2023.09.020_bib24","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/j.jaci.2020.01.009","article-title":"Activated pyrin domain containing 3 (NLRP3) inflammasome in neutrophilic chronic rhinosinusitis with nasal polyps (CRSwNP)","volume":"145","author":"Wei","year":"2020","journal-title":"J Allergy Clin Immunol"},{"issue":"suppl S29","key":"10.1016\/j.jaci.2023.09.020_bib25","first-page":"1","article-title":"European position paper on rhinosinusitis and nasal polyps, 2020","volume":"58","author":"Fokkens","year":"2020","journal-title":"Rhinology"},{"key":"10.1016\/j.jaci.2023.09.020_bib26","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jaci.2019.03.026","article-title":"Epithelium-derived cystatin SN\u00a0enhances eosinophil activation and infiltration through IL-5 in patients with\u00a0chronic rhinosinusitis with nasal polyps","volume":"144","author":"Yan","year":"2019","journal-title":"J Allergy Clin Immunol"},{"issue":"6521","key":"10.1016\/j.jaci.2023.09.020_bib27","doi-asserted-by":"crossref","DOI":"10.1126\/science.aay2002","article-title":"Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia","volume":"370","author":"Robinson","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.jaci.2023.09.020_bib28","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1038\/ni.3538","article-title":"NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations","volume":"17","author":"Mortimer","year":"2016","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib29","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/j.immuni.2016.10.009","article-title":"Bile acids control inflammation and metabolic disorder through inhibition of NLRP3 inflammasome","volume":"45","author":"Guo","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.jaci.2023.09.020_bib30","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01401-2022","article-title":"Inflammasome activation mediated by oxidized LDL in patients with sleep apnea and early subclinical atherosclerosis","volume":"61","author":"Diaz-Garcia","year":"2023","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaci.2023.09.020_bib31","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1038\/ncomms3909","article-title":"Adenosine is required for sustained inflammasome activation via the A(2)A receptor and the HIF-1alpha pathway","volume":"4","author":"Ouyang","year":"2013","journal-title":"Nat Commun"},{"key":"10.1016\/j.jaci.2023.09.020_bib32","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1161\/CIRCRESAHA.115.304437","article-title":"Moderate hypoxia potentiates interleukin-1beta production in activated human macrophages","volume":"115","author":"Folco","year":"2014","journal-title":"Circ Res"},{"key":"10.1016\/j.jaci.2023.09.020_bib33","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1159\/000526803","article-title":"IL-12 contributes to the development of asthma by targeting HIF-1alpha\/NLRP3 pathway through Runx3","volume":"183","author":"Sun","year":"2022","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib34","doi-asserted-by":"crossref","first-page":"2671","DOI":"10.1084\/jem.20162040","article-title":"Protein kinase D at the Golgi controls NLRP3 inflammasome activation","volume":"214","author":"Zhang","year":"2017","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaci.2023.09.020_bib35","doi-asserted-by":"crossref","DOI":"10.1128\/iai.00663-21","article-title":"Salmonella enterica serovar Typhimurium induces NAIP\/NLRC4- and NLRP3\/ASC-independent, caspase-4\u2013dependent inflammasome activation in human intestinal epithelial cells","volume":"90","author":"Naseer","year":"2022","journal-title":"Infect Immun"},{"key":"10.1016\/j.jaci.2023.09.020_bib36","volume":"8","author":"Yang","year":"2020","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.jaci.2023.09.020_bib37","doi-asserted-by":"crossref","DOI":"10.1002\/clt2.12168","article-title":"Transcriptome sequencing reveals altered ciliogenesis under hypoxia in nasal epithelial cells from chronic rhinosinusitis with nasal polyps","volume":"12","author":"Jiao","year":"2022","journal-title":"Clin Transl Allergy"},{"key":"10.1016\/j.jaci.2023.09.020_bib38","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.jaci.2011.11.033","article-title":"The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter","volume":"129","author":"Hirota","year":"2012","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib39","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1002\/lary.21921","article-title":"Transepithelial ion transport is suppressed in hypoxic sinonasal epithelium","volume":"121","author":"Blount","year":"2011","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jaci.2023.09.020_bib40","doi-asserted-by":"crossref","first-page":"208","DOI":"10.2500\/ajra.2014.28.4055","article-title":"Cigarette smoke promotes eosinophilic inflammation, airway remodeling, and nasal polyps in a murine polyp model","volume":"28","author":"Lee","year":"2014","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jaci.2023.09.020_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexcr.2019.05.023","article-title":"The role of the XBP-1\/AGR2 signaling pathway in the regulation of airway Mucin5ac hypersecretion under hypoxia","volume":"382","author":"Xu","year":"2019","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.jaci.2023.09.020_bib42","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.imlet.2017.10.006","article-title":"IL-1beta upregulates Muc5ac expression via NF-kappaB-induced HIF-1alpha in asthma","volume":"192","author":"Wu","year":"2017","journal-title":"Immunol Lett"},{"key":"10.1016\/j.jaci.2023.09.020_bib43","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.jaci.2010.12.011","article-title":"Role of p63\/p73 in epithelial remodeling and their response to steroid treatment in nasal polyposis","volume":"127","author":"Li","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib44","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1111\/all.13074","article-title":"Increase of poorly proliferated p63+\/Ki67+ basal cells forming multiple layers in the aberrant remodeled epithelium in nasal polyps","volume":"72","author":"Zhao","year":"2017","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2023.09.020_bib45","first-page":"599","article-title":"Induction of airway progenitor cells via p63 and KLF11 by Rho-kinase inhibitor Y27632 in hTERT-human nasal epithelial cells","volume":"11","author":"Kaneko","year":"2019","journal-title":"Am J Transl Res"},{"key":"10.1016\/j.jaci.2023.09.020_bib46","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1016\/j.jaci.2017.11.032","article-title":"CD151, a novel host factor of nuclear export signaling in influenza virus infection","volume":"141","author":"Qiao","year":"2018","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2023.09.020_bib47","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1038\/s41564-019-0405-x","article-title":"Hypoxia-induced human deoxyribonuclease I is a cellular restriction factor of hepatitis B virus","volume":"4","author":"Hallez","year":"2019","journal-title":"Nat Microbiol"},{"key":"10.1016\/j.jaci.2023.09.020_bib48","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/j.immuni.2021.03.003","article-title":"The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts","volume":"54","author":"Friscic","year":"2021","journal-title":"Immunity"},{"key":"10.1016\/j.jaci.2023.09.020_bib49","doi-asserted-by":"crossref","first-page":"4664","DOI":"10.1038\/s41467-021-25015-6","article-title":"SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation","volume":"12","author":"Pan","year":"2021","journal-title":"Nat Commun"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674923012010?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674923012010?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T09:43:29Z","timestamp":1758793409000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674923012010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":49,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S0091674923012010"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2023.09.020","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypoxia-inducible factor 1\u03b1 activates the NLRP3 inflammasome to regulate epithelial differentiation in chronic rhinosinusitis","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2023.09.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}