{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T20:55:50Z","timestamp":1790110550545,"version":"4.0.1"},"reference-count":65,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T00:00:00Z","timestamp":1746230400000},"content-version":"am","delay-in-days":367,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.jaci.2024.01.017","type":"journal-article","created":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T23:49:59Z","timestamp":1706917799000},"page":"1355-1368","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"title":["Epithelial overexpression of IL-33 induces eosinophilic esophagitis dependent on IL-13"],"prefix":"10.1016","volume":"153","author":[{"given":"Mia Y.","family":"Masuda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace C.","family":"Pyon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huijun","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William E.","family":"LeSuer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arina","family":"Putikova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adelyn","family":"Dao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danna R.","family":"Ortiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliviya R.","family":"Schulze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Fritz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takao","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Iijima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres J.","family":"Klein-Szanto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masataka","family":"Shimonosono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Flashner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Morimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rish K.","family":"Pai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew A.","family":"Rank","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirohito","family":"Kita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin L.","family":"Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9909-0445","authenticated-orcid":false,"given":"Alfred D.","family":"Doyle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2024.01.017_bib1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jaci.2018.05.008","article-title":"Epithelial origin of eosinophilic esophagitis","volume":"142","author":"Rochman","year":"2018","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib2","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1053\/j.gastro.2017.06.065","article-title":"Pathophysiology of eosinophilic esophagitis","volume":"154","author":"O\u2019Shea","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jaci.2024.01.017_bib3","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1038\/ng.3033","article-title":"Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease","volume":"46","author":"Kottyan","year":"2014","journal-title":"Nat Genet"},{"key":"10.1016\/j.jaci.2024.01.017_bib4","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/all.12570","article-title":"Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation","volume":"70","author":"Simon","year":"2015","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2024.01.017_bib5","doi-asserted-by":"crossref","first-page":"G13","DOI":"10.1152\/ajpgi.00290.2015","article-title":"Elevated IL-33 expression is associated with pediatric eosinophilic esophagitis, and exogenous IL-33 promotes eosinophilic esophagitis development in mice","volume":"310","author":"Judd","year":"2016","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.jaci.2024.01.017_bib6","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-17541-5","article-title":"IL-33 is induced in undifferentiated, non-dividing esophageal epithelial cells in eosinophilic esophagitis","volume":"7","author":"Travers","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jaci.2024.01.017_bib7","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/imr.12552","article-title":"IL-33: biological properties, functions, and roles in airway disease","volume":"278","author":"Drake","year":"2017","journal-title":"Immunol Rev"},{"key":"10.1016\/j.jaci.2024.01.017_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2022.155891","article-title":"Interleukin-33 (IL-33): a critical review of its biology and the mechanisms involved in its release as a potent extracellular cytokine","volume":"156","author":"Cayrol","year":"2022","journal-title":"Cytokine"},{"key":"10.1016\/j.jaci.2024.01.017_bib9","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1053\/j.gastro.2005.06.027","article-title":"Epicutaneous antigen exposure primes for experimental eosinophilic esophagitis in mice","volume":"129","author":"Akei","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jaci.2024.01.017_bib10","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1038\/nm.3281","article-title":"Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis","volume":"19","author":"Noti","year":"2013","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2024.01.017_bib11","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.gastro.2003.07.007","article-title":"Intratracheal IL-13 induces eosinophilic esophagitis by an IL-5, eotaxin-1, and STAT6-dependent mechanism","volume":"125","author":"Mishra","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jaci.2024.01.017_bib12","doi-asserted-by":"crossref","first-page":"660","DOI":"10.4049\/jimmunol.1000471","article-title":"IL-13 induces esophageal remodeling and gene expression by an eosinophil-independent, IL-13R alpha 2-inhibited pathway","volume":"185","author":"Zuo","year":"2010","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib13","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1016\/j.jaci.2023.07.021","article-title":"IL-13-induced STAT3-dependent signaling networks regulate esophageal epithelial proliferation in eosinophilic esophagitis","volume":"152","author":"Marella","year":"2023","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib14","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1136\/gutjnl-2012-303631","article-title":"Local hypersensitivity reaction in transgenic mice with squamous epithelial IL-5 overexpression provides a novel model of eosinophilic oesophagitis","volume":"63","author":"Masterson","year":"2014","journal-title":"Gut"},{"key":"10.1016\/j.jaci.2024.01.017_bib15","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1111\/all.15510","article-title":"Epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis","volume":"78","author":"Avlas","year":"2023","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2024.01.017_bib17","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/j.jaci.2016.02.034","article-title":"Allergic skin sensitization promotes eosinophilic esophagitis through the IL-33-basophil axis in mice","volume":"138","author":"Venturelli","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib18","doi-asserted-by":"crossref","first-page":"750","DOI":"10.4049\/jimmunol.1402057","article-title":"Severe neutrophil-dominated inflammation and enhanced myelopoiesis in IL-33-overexpressing CMV\/IL33 mice","volume":"194","author":"Talabot-Ayer","year":"2015","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib19","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jaut.2014.02.012","article-title":"Altered subcellular localization of IL-33 leads to non-resolving lethal inflammation","volume":"55","author":"Bessa","year":"2014","journal-title":"J Autoimmun"},{"key":"10.1016\/j.jaci.2024.01.017_bib20","doi-asserted-by":"crossref","first-page":"15502","DOI":"10.1073\/pnas.1410700111","article-title":"Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells","volume":"111","author":"Lefrancais","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jaci.2024.01.017_bib21","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1182\/blood-2013-01-473405","article-title":"Expression of the secondary granule proteins major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX) is required for eosinophilopoiesis in mice","volume":"122","author":"Doyle","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.jaci.2024.01.017_bib22","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s11248-011-9537-3","article-title":"The construction of transgenic and gene knockout\/knockin mouse models of human disease","volume":"21","author":"Doyle","year":"2012","journal-title":"Transgenic Res"},{"key":"10.1016\/j.jaci.2024.01.017_bib23","first-page":"L264","article-title":"Ablation of the SERCA3 gene alters epithelium-dependent relaxation in mouse tracheal smooth muscle","volume":"277","author":"Kao","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jaci.2024.01.017_bib24","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/all.15457","article-title":"Detergent exposure induces epithelial barrier dysfunction and eosinophilic inflammation in the esophagus","volume":"78","author":"Doyle","year":"2023","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2024.01.017_bib25","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1016\/j.jcmgh.2022.01.018","article-title":"CD73(+) epithelial progenitor cells that contribute to homeostasis and renewal are depleted in eosinophilic esophagitis","volume":"13","author":"Hara","year":"2022","journal-title":"Cell Mol Gastroenterol Hepatol"},{"key":"10.1016\/j.jaci.2024.01.017_bib26","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.jcmgh.2017.12.013","article-title":"The esophageal organoid system reveals functional interplay between notch and cytokines in reactive epithelial changes","volume":"5","author":"Kasagi","year":"2018","journal-title":"Cell Mol Gastroenterol Hepatol"},{"key":"10.1016\/j.jaci.2024.01.017_bib27","first-page":"1","article-title":"Newly developed and validated eosinophilic esophagitis histology scoring system and evidence that it outperforms peak eosinophil count for disease diagnosis and monitoring","volume":"30","author":"Collins","year":"2017","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.jaci.2024.01.017_bib65","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaci.2024.01.017_bib66","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaci.2024.01.017_bib28","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol"},{"key":"10.1016\/j.jaci.2024.01.017_bib29","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1186\/s12859-018-2486-6","article-title":"iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data","volume":"19","author":"Ge","year":"2018","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.jaci.2024.01.017_bib30","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.1093\/bioinformatics\/btz931","article-title":"ShinyGO: a graphical gene-set enrichment tool for animals and plants","volume":"36","author":"Ge","year":"2020","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaci.2024.01.017_bib31","doi-asserted-by":"crossref","first-page":"W191","DOI":"10.1093\/nar\/gkz369","article-title":"Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)","volume":"47","author":"Raudvere","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jaci.2024.01.017_bib32","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.jaci.2022.01.014","article-title":"Blocking the inhibitory receptor programmed cell death 1 prevents allergic immune response and anaphylaxis in mice","volume":"150","author":"Lama","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib33","doi-asserted-by":"crossref","first-page":"e106","DOI":"10.1002\/cpsc.106","article-title":"Modeling epithelial homeostasis and reactive epithelial changes in human and murine three-dimensional esophageal organoids","volume":"52","author":"Nakagawa","year":"2020","journal-title":"Curr Protoc Stem Cell Biol"},{"key":"10.1016\/j.jaci.2024.01.017_bib34","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1038\/sj.onc.1200937","article-title":"The targeting of the cyclin D1 oncogene by an Epstein-Barr virus promoter in transgenic mice causes dysplasia in the tongue, esophagus and forestomach","volume":"14","author":"Nakagawa","year":"1997","journal-title":"Oncogene"},{"key":"10.1016\/j.jaci.2024.01.017_bib35","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.anai.2015.09.015","article-title":"High rate of failure to thrive in a pediatric cohort with eosinophilic esophagitis","volume":"116","author":"Paquet","year":"2016","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib36","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1097\/RLU.0b013e318286c025","article-title":"FDG PET\/CT in eosinophilic esophagitis","volume":"39","author":"Dong","year":"2014","journal-title":"Clin Nucl Med"},{"key":"10.1016\/j.jaci.2024.01.017_bib37","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1111\/dote.12044","article-title":"Thickened esophagus as an unusual manifestation of eosinophilic esophagitis","volume":"29","author":"Aswakul","year":"2016","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.jaci.2024.01.017_bib38","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1097\/01.mcg.0000225590.08825.77","article-title":"Prevalence of eosinophilic esophagitis in adults with food bolus obstruction of the esophagus","volume":"41","author":"Kerlin","year":"2007","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.jaci.2024.01.017_bib39","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abp9940","article-title":"Epithelial-intrinsic defects in TGFbetaR signaling drive local allergic inflammation manifesting as eosinophilic esophagitis","volume":"8","author":"Laky","year":"2023","journal-title":"Sci Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib40","doi-asserted-by":"crossref","first-page":"eaaz7773","DOI":"10.1126\/scitranslmed.aaz7773","article-title":"Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis","volume":"12","author":"Azouz","year":"2020","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jaci.2024.01.017_bib41","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1053\/j.gastro.2013.08.046","article-title":"Molecular diagnosis of eosinophilic esophagitis by gene expression profiling","volume":"145","author":"Wen","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jaci.2024.01.017_bib42","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1172\/JCI26679","article-title":"Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis","volume":"116","author":"Blanchard","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2024.01.017_bib43","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/gene.2014.27","article-title":"Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing","volume":"15","author":"Sherrill","year":"2014","journal-title":"Genes Immun"},{"key":"10.1016\/j.jaci.2024.01.017_bib44","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1016\/j.jaci.2016.02.024","article-title":"Food-specific IgG4 is associated with eosinophilic esophagitis","volume":"138","author":"Wright","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib45","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1053\/j.gastro.2014.05.036","article-title":"Eosinophilic esophagitis in adults is associated with IgG4 and not mediated by IgE","volume":"147","author":"Clayton","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jaci.2024.01.017_bib46","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1365-2222.2009.03207.x","article-title":"Immunoglobulin G4: an odd antibody","volume":"39","author":"Aalberse","year":"2009","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2024.01.017_bib47","doi-asserted-by":"crossref","first-page":"958","DOI":"10.3389\/fimmu.2018.00958","article-title":"Potential of murine IgG1 and human IgG4 to inhibit the classical complement and Fcgamma receptor activation pathways","volume":"9","author":"Lilienthal","year":"2018","journal-title":"Front Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib48","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1136\/gutjnl-2015-310341","article-title":"Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis","volume":"66","author":"Whelan","year":"2017","journal-title":"Gut"},{"key":"10.1016\/j.jaci.2024.01.017_bib49","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1056\/NEJMoa2205982","article-title":"Dupilumab in adults and adolescents with eosinophilic esophagitis","volume":"387","author":"Dellon","year":"2022","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2024.01.017_bib50","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1016\/j.jaci.2007.10.024","article-title":"IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids","volume":"120","author":"Blanchard","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib51","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/S1542-3565(05)00885-2","article-title":"Eosinophilic esophagitis: a 10-year experience in 381 children","volume":"3","author":"Liacouras","year":"2005","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.jaci.2024.01.017_bib52","first-page":"380","article-title":"Primary eosinophilic esophagitis in children: successful treatment with oral corticosteroids","volume":"26","author":"Liacouras","year":"1998","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jaci.2024.01.017_bib53","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1016\/j.cgh.2018.04.013","article-title":"Model to determine the optimal dietary elimination strategy for treatment of eosinophilic esophagitis","volume":"16","author":"Zhan","year":"2018","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.jaci.2024.01.017_bib54","doi-asserted-by":"crossref","first-page":"403","DOI":"10.4049\/jimmunol.1200259","article-title":"Full-length IL-33 promotes inflammation but not Th2 response in\u00a0vivo in an ST2-independent fashion","volume":"189","author":"Luzina","year":"2012","journal-title":"J Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib55","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1053\/j.gastro.2022.04.026","article-title":"A chromosomal duplication encompassing interleukin-33 causes a novel hyper IgE phenotype characterized by eosinophilic esophagitis and generalized autoimmunity","volume":"163","author":"Marwaha","year":"2022","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jaci.2024.01.017_bib56","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1172\/JCI78850","article-title":"BMP-driven NRF2 activation in esophageal basal cell differentiation and eosinophilic esophagitis","volume":"125","author":"Jiang","year":"2015","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaci.2024.01.017_bib57","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.99922","article-title":"Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis","volume":"3","author":"Sherrill","year":"2018","journal-title":"JCI Insight"},{"key":"10.1016\/j.jaci.2024.01.017_bib58","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1111\/all.15762","article-title":"Laundry detergents and surfactants-induced eosinophilic airway inflammation by increasing IL-33 expression and activating ILC2s","volume":"78","author":"Saito","year":"2023","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2024.01.017_bib59","first-page":"368","article-title":"Redefining the role of lymphocytes in gastroesophageal reflux disease and eosinophilic esophagitis","volume":"23","author":"Basseri","year":"2010","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.jaci.2024.01.017_bib60","doi-asserted-by":"crossref","DOI":"10.1093\/dote\/dox122","article-title":"Pollen-food allergy syndrome is a common allergic comorbidity in adults with eosinophilic esophagitis","volume":"31","author":"Letner","year":"2018","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.jaci.2024.01.017_bib61","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1046\/j.1523-1747.2000.00144.x","article-title":"Conditional gene expression in the epidermis of transgenic mice using the tetracycline-regulated transactivators tTA and rTA linked to the keratin 5 promoter","volume":"115","author":"Diamond","year":"2000","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaci.2024.01.017_bib62","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.anai.2020.03.020","article-title":"AGA institute and the joint task force on allergy-immunology practice parameters clinical guidelines for the management of eosinophilic esophagitis","volume":"124","author":"Hirano","year":"2020","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib63","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.jaci.2011.11.044","article-title":"Reslizumab in children and adolescents with eosinophilic esophagitis: results of a double-blind, randomized, placebo-controlled trial","volume":"129","author":"Spergel","year":"2012","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.01.017_bib64","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1053\/j.gastro.2011.07.044","article-title":"An antibody against IL-5 reduces numbers of esophageal intraepithelial eosinophils in children with eosinophilic esophagitis","volume":"141","author":"Assa\u2019ad","year":"2011","journal-title":"Gastroenterology"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674924001209?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674924001209?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T07:34:07Z","timestamp":1714721647000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674924001209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":65,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["S0091674924001209"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2024.01.017","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Epithelial overexpression of IL-33 induces eosinophilic esophagitis dependent on IL-13","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2024.01.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}