{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:32:24Z","timestamp":1791930744548,"version":"4.3.4"},"reference-count":41,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T00:00:00Z","timestamp":1756944000000},"content-version":"am","delay-in-days":368,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000016","name":"U.S. Department of Health and Human Services","doi-asserted-by":"publisher","award":["1UM1AI160040"],"award-info":[{"award-number":["1UM1AI160040"]}],"id":[{"id":"10.13039\/100000016","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000016","name":"U.S. Department of Health and Human Services","doi-asserted-by":"publisher","award":["UM2AI117870"],"award-info":[{"award-number":["UM2AI117870"]}],"id":[{"id":"10.13039\/100000016","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000016","name":"U.S. Department of Health and Human Services","doi-asserted-by":"publisher","award":["1UM1AI114271-01"],"award-info":[{"award-number":["1UM1AI114271-01"]}],"id":[{"id":"10.13039\/100000016","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["1UM1AI160040"],"award-info":[{"award-number":["1UM1AI160040"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["1UM1AI114271-01"],"award-info":[{"award-number":["1UM1AI114271-01"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.jaci.2024.04.022","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T15:17:08Z","timestamp":1715008628000},"page":"735-744.e10","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["A pediatric randomized, controlled trial of German cockroach subcutaneous immunotherapy"],"prefix":"10.1016","volume":"154","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2626-0682","authenticated-orcid":false,"given":"Edward","family":"Zoratti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Wood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Pom\u00e9s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Da Silva Antunes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew C.","family":"Altman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basilin","family":"Benson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa M.","family":"Wheatley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agustin","family":"Calatroni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic F.","family":"Little","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Pongracic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Makhija","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gurjit K.","family":"Khurana Hershey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael G.","family":"Sherenian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Rivera-Spoljaric","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey R.","family":"Stokes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle A.","family":"Gill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca S.","family":"Gruchalla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Chambliss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew H.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meyer","family":"Kattan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula J.","family":"Busse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard B.","family":"Bacharier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Sheehan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haejin.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill","family":"Glesner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Gergen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alkis","family":"Togias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica L.","family":"Baucom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia M.","family":"Visness","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Sette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William W.","family":"Busse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaci.2024.04.022_bib1","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1056\/NEJM199705083361904","article-title":"The role of cockroach allergy and exposure to cockroach allergen in causing morbidity among inner-city children with asthma","volume":"336","author":"Rosenstreich","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2024.04.022_bib2","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1056\/NEJMoa032097","article-title":"Results of a home-based environmental intervention among urban children with asthma","volume":"351","author":"Morgan","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2024.04.022_bib3","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.jaci.2013.04.061","article-title":"Environmental assessment and exposure reduction of cockroaches: a practice parameter","volume":"132","author":"Portnoy","year":"2013","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib4","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.jaci.2022.01.016","article-title":"Diverse immune mechanisms of allergen immunotherapy for allergic rhinitis with and without asthma","volume":"149","author":"Shamji","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib5","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3109\/02770908809071367","article-title":"The role of immunotherapy in cockroach asthma","volume":"25","author":"Kang","year":"1988","journal-title":"J Asthma"},{"key":"10.1016\/j.jaci.2024.04.022_bib6","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1111\/j.1365-2362.2011.02480.x","article-title":"Clinico-immunological changes post-immunotherapy with Periplaneta americana","volume":"41","author":"Srivastava","year":"2011","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.jaci.2024.04.022_bib7","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/j.jaci.2013.08.047","article-title":"Development of cockroach immunotherapy by the Inner-City Asthma Consortium","volume":"133","author":"Wood","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib8","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1016\/j.jaci.2018.07.036","article-title":"Allergen content in German cockroach extracts and sensitization profiles to a new expanded set of cockroach allergens determine in\u00a0vitro extract potency for IgE reactivity","volume":"143","author":"Glesner","year":"2019","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib9","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1111\/pai.13480","article-title":"Development of nasal allergen challenge with cockroach in children with asthma","volume":"32","author":"Rudman Spergel","year":"2021","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib10","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/j.cell.2016.09.050","article-title":"Regulatory T cell specificity directs tolerance versus allergy against aeroantigens in humans","volume":"167","author":"Bacher","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.jaci.2024.04.022_bib11","doi-asserted-by":"crossref","DOI":"10.1002\/clt2.12073","article-title":"Heterogeneity of magnitude, allergen immunodominance, and cytokine polarization of cockroach allergen-specific T cell responses in allergic sensitized children","volume":"11","author":"da Silva Antunes","year":"2021","journal-title":"Clin Transl Allergy"},{"key":"10.1016\/j.jaci.2024.04.022_bib12","doi-asserted-by":"crossref","first-page":"630","DOI":"10.3389\/fimmu.2014.00630","article-title":"Plasticity of human CD4 T cell subsets","volume":"5","author":"Geginat","year":"2014","journal-title":"Front Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib13","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3389\/fimmu.2018.00235","article-title":"Allergen and epitope targets of mouse-specific T cell responses in allergy and asthma","volume":"9","author":"Schulten","year":"2018","journal-title":"Front Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib14","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/s41590-019-0347-8","article-title":"Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children","volume":"20","author":"Altman","year":"2019","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib15","doi-asserted-by":"crossref","DOI":"10.1093\/bioinformatics\/btad279","article-title":"Kimma: flexible linear mixed effects modeling with kinship covariance for RNA-seq data","volume":"39","author":"Dill-McFarland","year":"2023","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaci.2024.04.022_bib16","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1186\/1471-2105-9-559","article-title":"WGCNA: an R package for weighted correlation network analysis","volume":"9","author":"Langfelder","year":"2008","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.jaci.2024.04.022_bib17","doi-asserted-by":"crossref","DOI":"10.18637\/jss.v046.i11","article-title":"Fast R functions for robust correlations and hierarchical clustering","volume":"46","author":"Langfelder","year":"2012","journal-title":"J Stat Softw"},{"key":"10.1016\/j.jaci.2024.04.022_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v059.i05","article-title":"mediation: R package for causal mediation analysis","volume":"59","author":"Tingley","year":"2014","journal-title":"J Stat Softw"},{"key":"10.1016\/j.jaci.2024.04.022_bib19","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/ni.3049","article-title":"The immunology of asthma","volume":"16","author":"Lambrecht","year":"2015","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib20","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/nri3831","article-title":"Type 2 cytokines: mechanisms and therapeutic strategies","volume":"15","author":"Wynn","year":"2015","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib21","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.jaci.2009.10.060","article-title":"Speaking the same language: the World Allergy Organization subcutaneous immunotherapy systemic reaction grading system","volume":"125","author":"Cox","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib22","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.jaci.2022.08.029","article-title":"Effects of combination treatment with tezepelumab and allergen immunotherapy on nasal responses to allergen: a randomized controlled trial","volume":"151","author":"Corren","year":"2023","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib23","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1001\/jama.2016.21040","article-title":"Effect of 2 years of treatment with sublingual grass pollen immunotherapy on nasal response to allergen challenge at 3 years among patients with moderate to severe seasonal allergic rhinitis: the GRASS randomized clinical trial","volume":"317","author":"Scadding","year":"2017","journal-title":"JAMA"},{"key":"10.1016\/j.jaci.2024.04.022_bib24","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.jaci.2023.02.014","article-title":"Nasal allergen challenge (NAC): practical aspects and applications from an EU\/US perspective\u2014a Work Group Report of the AAAAI Rhinitis, Rhinosinusitis and Ocular Allergy Committee","volume":"151","author":"Cho","year":"2023","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib25","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1016\/j.jaci.2023.06.025","article-title":"Nasal and blood transcriptomic pathways underpinning the clinical response to grass pollen immunotherapy","volume":"152","author":"Altman","year":"2023","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib26","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1016\/j.jaci.2020.02.024","article-title":"Nasal allergen challenge and environmental exposure chamber challenge: a randomized trial comparing clinical and biological responses to cat allergen","volume":"145","author":"Larson","year":"2020","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib27","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.molimm.2023.03.001","article-title":"Cockroach allergy: understanding complex immune responses to develop novel therapies","volume":"156","author":"Pomes","year":"2023","journal-title":"Mol Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib28","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1111\/cea.13604","article-title":"Measurement of German cockroach allergens and their isoforms in allergen extracts with mass spectrometry","volume":"50","author":"Mindaye","year":"2020","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2024.04.022_bib29","article-title":"IgE and T cell reactivity to a comprehensive panel of cockroach allergens in relation to disease","volume":"11","author":"Pomes","year":"2020","journal-title":"Front Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib30","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.jaci.2019.05.036","article-title":"Cockroach allergen component analysis of children with or without asthma\u00a0and\u00a0rhinitis in an inner-city birth cohort","volume":"144","author":"Pomes","year":"2019","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib31","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/all.13338","article-title":"Diagnostic relevance of IgE sensitization profiles to eight recombinant Phleum pratense molecules","volume":"73","author":"Cipriani","year":"2018","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2024.04.022_bib32","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.jaci.2011.10.045","article-title":"Molecular profiles of IgE to Phleum pratense in children with grass pollen allergy: implications for specific immunotherapy","volume":"129","author":"Tripodi","year":"2012","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib33","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1016\/j.jaip.2021.03.029","article-title":"Immunological responses and biomarkers for allergen-specific immunotherapy against inhaled allergens","volume":"9","author":"Shamji","year":"2021","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jaci.2024.04.022_bib34","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.jaci.2021.05.039","article-title":"Novel antibody cocktail targeting Bet v 1 rapidly and sustainably treats birch allergy symptoms in a phase 1 study","volume":"149","author":"Gevaert","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib35","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1038\/s41467-018-03636-8","article-title":"Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement","volume":"9","author":"Orengo","year":"2018","journal-title":"Nat Commun"},{"key":"10.1016\/j.jaci.2024.04.022_bib36","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/s41577-022-00786-1","article-title":"Allergen immunotherapy: past, present and future","volume":"23","author":"Durham","year":"2023","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib37","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1398-9995.2011.02745.x","article-title":"Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy","volume":"67","author":"Shamji","year":"2012","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2024.04.022_bib38","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02782-2021","article-title":"Allergen provocation tests in respiratory research: building on 50 years of experience","volume":"60","author":"Gauvreau","year":"2022","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaci.2024.04.022_bib39","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1067\/mai.2003.1592","article-title":"Rhinitis and asthma: evidence for respiratory system integration","volume":"111","author":"Togias","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2024.04.022_bib40","doi-asserted-by":"crossref","DOI":"10.1002\/clt2.12073","article-title":"Heterogeneity of magnitude, allergen immunodominance, and cytokine polarization of cockroach allergen-specific T cell responses in allergic sensitized children","volume":"11","author":"da Silva Antunes","year":"2021","journal-title":"Clin Transl Allergy"},{"key":"10.1016\/j.jaci.2024.04.022_bib41","first-page":"43","article-title":"limma powers differential expression analyses for RNA-sequencing and microarray studies","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009167492400455X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009167492400455X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T04:46:14Z","timestamp":1725511574000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S009167492400455X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":41,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S009167492400455X"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2024.04.022","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A pediatric randomized, controlled trial of German cockroach subcutaneous immunotherapy","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2024.04.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 American Academy of Allergy, Asthma & Immunology","name":"copyright","label":"Copyright"}]}}