{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:58:24Z","timestamp":1791197904297,"version":"4.1.0"},"reference-count":59,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003554","name":"Lundbeckfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004836","name":"Independent Research Fund Denmark","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004836","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacionline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.jaci.2026.05.034","type":"journal-article","created":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T15:26:52Z","timestamp":1782746812000},"page":"960-969","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Maternal antibiotic exposure alters the newborn metabolomic profile and increases the risk of respiratory infections in offspring: A 13-year longitudinal birth cohort study"],"prefix":"10.1016","volume":"158","author":[{"given":"Marie","family":"Hauerslev","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton","family":"Kjellberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Thorsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Brix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamo","family":"Sultan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren","family":"S\u00f8rensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeleine","family":"Ernst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob","family":"Stokholm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"B\u00f8nnelykke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Chawes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6383-8845","authenticated-orcid":false,"given":"Nicklas","family":"Brustad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10303","key":"10.1016\/j.jaci.2026.05.034_bib1","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/S0140-6736(21)01207-1","article-title":"Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019","volume":"398","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.jaci.2026.05.034_bib2","doi-asserted-by":"crossref","first-page":"2102395","DOI":"10.1183\/13993003.02395-2021","article-title":"Early-life respiratory tract infections and the risk of school-age lower lung function and asthma: a meta-analysis of 150 000 European children","volume":"60","author":"van Meel","year":"2022","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaci.2026.05.034_bib3","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/s12887-023-03870-0","article-title":"Early exposure to infections increases the risk of allergic rhinitis-a systematic review and meta-analysis","volume":"23","author":"Chen","year":"2023","journal-title":"BMC Pediatr"},{"key":"10.1016\/j.jaci.2026.05.034_bib4","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1001\/jamapsychiatry.2018.3428","article-title":"A nationwide study in Denmark of the association between treated infections and the subsequent risk of treated mental disorders in children and adolescents","volume":"76","author":"K\u00f6hler-Forsberg","year":"2019","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jaci.2026.05.034_bib5","article-title":"Maternal use of antibiotics and the risk of childhood febrile seizures: a danish population-based cohort","volume":"8","author":"Gray","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jaci.2026.05.034_bib6","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.jpeds.2016.12.046","article-title":"Antibiotics in pregnancy increase children\u2019s risk of otitis media and ventilation tubes","volume":"183","author":"Pedersen","year":"2017","journal-title":"J Pediatr"},{"key":"10.1016\/j.jaci.2026.05.034_bib7","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.jaci.2023.11.019","article-title":"Key risk factors of asthma-like symptoms are mediated through infection burden in early childhood","volume":"153","author":"Kyvsgaard","year":"2024","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2026.05.034_bib8","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/ije\/dyx272","article-title":"Maternal antibiotic exposure during pregnancy and hospitalization with infection in offspring: a population-based cohort study","volume":"47","author":"Miller","year":"2018","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.jaci.2026.05.034_bib9","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/S2213-2600(14)70152-3","article-title":"Maternal propensity for infections and risk of childhood asthma: a registry-based cohort study","volume":"2","author":"Stokholm","year":"2014","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.jaci.2026.05.034_bib10","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/s41467-017-02573-2","article-title":"Maturation of the gut microbiome and risk of asthma in childhood","volume":"9","author":"Stokholm","year":"2018","journal-title":"Nat Commun"},{"key":"10.1016\/j.jaci.2026.05.034_bib11","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1111\/apa.15733","article-title":"Use of antibiotics during pregnancy is associated with infection in children at four years of age in Portugal","volume":"110","author":"Cunha","year":"2021","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.jaci.2026.05.034_bib12","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2017-0933","article-title":"Epidemiology and risk factors of infection in early childhood","volume":"141","author":"Vissing","year":"2018","journal-title":"Pediatrics"},{"key":"10.1016\/j.jaci.2026.05.034_bib13","doi-asserted-by":"crossref","first-page":"5001","DOI":"10.1038\/s41467-019-12989-7","article-title":"Infant airway microbiota and topical immune perturbations in the origins of childhood asthma","volume":"10","author":"Thorsen","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.jaci.2026.05.034_bib14","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1111\/cea.12213","article-title":"Deep phenotyping of the unselected COPSAC2010 birth cohort study","volume":"43","author":"Bisgaard","year":"2013","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jaci.2026.05.034_bib15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0082932","article-title":"Prevalence and predictors of antibiotic administration during pregnancy and birth","volume":"8","author":"Stokholm","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jaci.2026.05.034_bib16","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.53284","article-title":"Burden of infections in early life and risk of infections and systemic antibiotics use in childhood","volume":"8","author":"Brustad","year":"2025","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.jaci.2026.05.034_bib17","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1136\/thorax-2024-221460","article-title":"Urban metabolic and airway immune profiles increase the risk of infections in early childhood","volume":"79","author":"Brustad","year":"2024","journal-title":"Thorax"},{"key":"10.1016\/j.jaci.2026.05.034_bib18","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1056\/NEJMoa1211592","article-title":"Rhinovirus wheezing illness and genetic risk of childhood-onset asthma","volume":"368","author":"Cal\u0131\u015fkan","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaci.2026.05.034_bib19","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1093\/infdis\/jiy582","article-title":"FUT2 genetic variants and reported respiratory and gastrointestinal illnesses during infancy","volume":"219","author":"Barton","year":"2019","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jaci.2026.05.034_bib20","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/s41467-017-00257-5","article-title":"Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections","volume":"8","author":"Tian","year":"2017","journal-title":"Nat Commun"},{"key":"10.1016\/j.jaci.2026.05.034_bib21","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/s41467-020-14308-x","article-title":"Prenatal dietary supplements influence the infant airway microbiota in a randomized factorial clinical trial","volume":"11","author":"Hjelms\u00f8","year":"2020","journal-title":"Nat Commun"},{"key":"10.1016\/j.jaci.2026.05.034_bib22","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/s40168-016-0215-9","article-title":"The developing hypopharyngeal microbiota in early life","volume":"4","author":"Mortensen","year":"2016","journal-title":"Microbiome"},{"key":"10.1016\/j.jaci.2026.05.034_bib23","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/s40168-020-00895-w","article-title":"Environmental shaping of the bacterial and fungal community in infant bed dust and correlations with the airway microbiota","volume":"8","author":"Gupta","year":"2020","journal-title":"Microbiome"},{"key":"10.1016\/j.jaci.2026.05.034_bib24","doi-asserted-by":"crossref","DOI":"10.3390\/metabo12020094","article-title":"Vertical transfer of metabolites detectable from newborn\u2019s dried blood spot samples using UPLC-MS: a chemometric study","volume":"12","author":"Olarini","year":"2022","journal-title":"Metabolites"},{"key":"10.1016\/j.jaci.2026.05.034_bib25","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02406-2021","article-title":"Neonatal metabolome of caesarean section and risk of childhood asthma","volume":"59","author":"Gurdeniz","year":"2022","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jaci.2026.05.034_bib26","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1164\/rccm.202008-3206OC","article-title":"Characteristics and mechanisms of a sphingolipid-associated childhood asthma endotype","volume":"203","author":"Rago","year":"2021","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jaci.2026.05.034_bib27","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s11306-007-0082-2","article-title":"Proposed minimum reporting standards for chemical analysis Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI)","volume":"3","author":"Sumner","year":"2007","journal-title":"Metabolomics"},{"key":"10.1016\/j.jaci.2026.05.034_bib28","doi-asserted-by":"crossref","first-page":"3713","DOI":"10.1111\/all.14862","article-title":"Neonatal airway immune profiles and asthma and allergy endpoints in childhood","volume":"76","author":"Chawes","year":"2021","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2026.05.034_bib29","doi-asserted-by":"crossref","DOI":"10.3791\/55800","article-title":"Noninvasive sampling of mucosal lining fluid for the quantification of in vivo upper airway immune-mediator levels","author":"Wolsk","year":"2017","journal-title":"J Vis Exp"},{"key":"10.1016\/j.jaci.2026.05.034_bib30","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"2018","journal-title":"Journal of the Royal Statistical Society, Series B (Methodological)"},{"key":"10.1016\/j.jaci.2026.05.034_bib31","doi-asserted-by":"crossref","first-page":"5930","DOI":"10.1038\/s41467-025-61392-y","article-title":"Air pollution\u2013induced proteomic alterations increase the risk of child respiratory infections","volume":"16","author":"Brustad","year":"2025","journal-title":"Nat Commun"},{"key":"10.1016\/j.jaci.2026.05.034_bib32","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1001\/jamapsychiatry.2025.0122","article-title":"Maternal inflammatory proteins in pregnancy and neurodevelopmental disorders at age 10 years","volume":"82","author":"Wang","year":"2025","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jaci.2026.05.034_bib33","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1038\/s41591-023-02685-x","article-title":"The infant gut virome is associated with preschool asthma risk independently of bacteria","volume":"30","author":"Leal Rodr\u00edguez","year":"2024","journal-title":"Nat Med"},{"key":"10.1016\/j.jaci.2026.05.034_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v028.i05","article-title":"Building predictive models in R using the caret package","volume":"28","author":"Kuhn","year":"2008","journal-title":"Journal of Statistical Software"},{"key":"10.1016\/j.jaci.2026.05.034_bib35","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1005752","article-title":"mixOmics: an R package for \u2019omics feature selection and multiple data integration","volume":"13","author":"Rohart","year":"2017","journal-title":"PLoS Comput Biol"},{"key":"10.1016\/j.jaci.2026.05.034_bib36","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s40264-024-01401-z","article-title":"In utero exposure to antibiotics and risk of serious infections in the first year of life","volume":"47","author":"Tisseyre","year":"2024","journal-title":"Drug Saf"},{"key":"10.1016\/j.jaci.2026.05.034_bib37","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1111\/jpc.15371","article-title":"Association of in utero antibiotic exposure on childhood ear infection trajectories: results from a national birth cohort study","volume":"57","author":"Hu","year":"2021","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.jaci.2026.05.034_bib38","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1017\/S0950268811001890","article-title":"Prenatal and postnatal risk factors for infantile pneumonia in a representative birth cohort","volume":"140","author":"Chen","year":"2011","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.jaci.2026.05.034_bib39","doi-asserted-by":"crossref","DOI":"10.2478\/v10001-006-0010-0","article-title":"The prenatal use of antibiotics and the development of allergic disease in one year old infants. A preliminary study","volume":"19","author":"J\u0119drychowski","year":"2006","journal-title":"Int J Occup Med Environ Health"},{"key":"10.1016\/j.jaci.2026.05.034_bib40","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1080\/02770903.2020.1734023","article-title":"Infant wheezing and prenatal antibiotic exposure and mode of delivery: a prospective birth cohort study","volume":"58","author":"Higgins","year":"2020","journal-title":"J Asthma"},{"key":"10.1016\/j.jaci.2026.05.034_bib41","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1002\/oby.21719","article-title":"Associations of prenatal and childhood antibiotic use with child body mass index at age 3 years","volume":"25","author":"Poulsen","year":"2017","journal-title":"Obesity"},{"key":"10.1016\/j.jaci.2026.05.034_bib42","article-title":"Relationship between maternal and first year of life dispensations of antibiotics and antiasthmatics","volume":"7","author":"Fossum","year":"2018","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.jaci.2026.05.034_bib43","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2021.1897210","article-title":"Maternal exposures and the infant gut microbiome: a systematic review with meta-analysis","volume":"13","author":"Grech","year":"2021","journal-title":"Gut Microbes"},{"key":"10.1016\/j.jaci.2026.05.034_bib44","doi-asserted-by":"crossref","DOI":"10.1111\/pai.70086","article-title":"Metabolomic studies of respiratory infections in early life: a narrative review","volume":"36","author":"Prince","year":"2025","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.jaci.2026.05.034_bib45","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1002\/jimd.12653","article-title":"Isovaleric aciduria identified by newborn screening: strategies to predict disease severity and stratify treatment","volume":"46","author":"M\u00fctze","year":"2023","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.jaci.2026.05.034_bib46","doi-asserted-by":"crossref","DOI":"10.5603\/gpl.102641","article-title":"Effects of gestational diabetes mellitus with different birth weight on genetic metabolism of newborns study.","author":"Xia","year":"2025","journal-title":"Ginekol Pol"},{"key":"10.1016\/j.jaci.2026.05.034_bib47","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-70660-8","article-title":"Nutritional status and extended metabolic screening in Egyptian children with uncomplicated type 1 diabetes","volume":"14","author":"Sakhr","year":"2024","journal-title":"Sci Rep"},{"key":"10.1016\/j.jaci.2026.05.034_bib48","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1023\/A:1005424331822","article-title":"Diagnosis of isovaleric acidaemia by tandem mass spectrometry: false positive result due to pivaloylcarnitine in a newborn screening programme","volume":"21","author":"Abdenur","year":"1998","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.jaci.2026.05.034_bib49","doi-asserted-by":"crossref","DOI":"10.1183\/23120541.00693-2023","article-title":"Purine degradation pathway metabolites at birth and the risk of lower respiratory tract infections in infancy","volume":"10","author":"Gutierrez","year":"2024","journal-title":"ERJ Open Res"},{"key":"10.1016\/j.jaci.2026.05.034_bib50","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.75170","article-title":"Early life infection and proinflammatory, atherogenic metabolomic and lipidomic profiles in infancy: a population-based cohort study","volume":"11","author":"Mansell","year":"2022","journal-title":"Elife"},{"key":"10.1016\/j.jaci.2026.05.034_bib51","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/s41390-018-0070-4","article-title":"Association of newborn screening metabolites with risk of wheezing in childhood","volume":"84","author":"Donovan","year":"2018","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jaci.2026.05.034_bib52","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.jaci.2024.02.024","article-title":"Metabolomic profiles during early childhood and risk of food allergies and asthma in multiethnic children from a prospective birth cohort","volume":"154","author":"Hong","year":"2024","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jaci.2026.05.034_bib53","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/all.15554","article-title":"Furan fatty acid metabolite in newborns predicts risk of asthma","volume":"78","author":"G\u00fcrdeniz","year":"2023","journal-title":"Allergy"},{"key":"10.1016\/j.jaci.2026.05.034_bib54","doi-asserted-by":"crossref","first-page":"2981","DOI":"10.1111\/all.16276","article-title":"Asthma development is associated with low mucosal IL-10 during viral infections in early life","volume":"79","author":"Melgaard","year":"2024","journal-title":"Allergy"},{"issue":"7896","key":"10.1016\/j.jaci.2026.05.034_bib55","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/s41586-021-04345-x","article-title":"Local and systemic responses to SARS-CoV-2 infection in children and adults","volume":"602","author":"Yoshida","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.jaci.2026.05.034_bib56","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.1016\/S2213-2600(14)70221-8","article-title":"Maternal antibiotic use and risk of asthma in offspring\u2014authors\u2019 reply","volume":"2","author":"Bisgaard","year":"2014","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.jaci.2026.05.034_bib57","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aax9929","article-title":"Delivery mode and gut microbial changes correlate with an increased risk of childhood asthma","volume":"12","author":"Stokholm","year":"2020","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jaci.2026.05.034_bib58","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.jpeds.2012.09.049","article-title":"Use of antibiotics during pregnancy increases the risk of asthma in early childhood","volume":"162","author":"Stensballe","year":"2013","journal-title":"J Pediatr"},{"key":"10.1016\/j.jaci.2026.05.034_bib59","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.g6979","article-title":"Antibiotics in fetal and early life and subsequent childhood asthma: nationwide population based study with sibling analysis","volume":"349","author":"\u00d6rtqvist","year":"2014","journal-title":"BMJ"}],"container-title":["Journal of Allergy and Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674926004483?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091674926004483?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:58:43Z","timestamp":1791194323000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091674926004483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":59,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S0091674926004483"],"URL":"https:\/\/doi.org\/10.1016\/j.jaci.2026.05.034","relation":{},"ISSN":["0091-6749"],"issn-type":[{"value":"0091-6749","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maternal antibiotic exposure alters the newborn metabolomic profile and increases the risk of respiratory infections in offspring: A 13-year longitudinal birth cohort study","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaci.2026.05.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology.","name":"copyright","label":"Copyright"}]}}