{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T21:02:32Z","timestamp":1757624552698,"version":"3.44.0"},"reference-count":84,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T00:00:00Z","timestamp":1683936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008982","name":"Qatar National Research Fund","doi-asserted-by":"publisher","award":["PPM1-1220-150017"],"award-info":[{"award-number":["PPM1-1220-150017"]}],"id":[{"id":"10.13039\/100008982","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019475","name":"Sidra Medicine","doi-asserted-by":"publisher","award":["SDR400127"],"award-info":[{"award-number":["SDR400127"]}],"id":[{"id":"10.13039\/100019475","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jaci-global.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology: Global"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.jacig.2023.100117","type":"journal-article","created":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T12:58:11Z","timestamp":1684414691000},"page":"100117","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Associations between HLA class II alleles and IgE sensitization to allergens in the Qatar Biobank cohort"],"prefix":"10.1016","volume":"2","author":[{"given":"Taushif","family":"Khan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella Marie","family":"Ledoux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferdousey","family":"Aziz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatima","family":"Al Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evonne","family":"Chin-Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manar","family":"Ata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed Yousuf","family":"Karim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1927-7072","authenticated-orcid":false,"given":"Nico","family":"Marr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacig.2023.100117_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000343018","article-title":"Pooling birth cohorts in allergy and asthma: European Union\u2013funded initiatives\u2014a MeDALL, CHICOS, ENRIECO, and GA(2)LEN joint paper","volume":"161","author":"Bousquet","year":"2013","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib2","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1007\/s12016-018-8710-3","article-title":"IgE-mediated food allergy","volume":"57","author":"Anvari","year":"2019","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib3","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/bs.ai.2018.03.002","article-title":"Molecular aspects of allergens and allergy","volume":"138","author":"Valenta","year":"2018","journal-title":"Adv Immunol"},{"issue":"2 suppl\u00a02","key":"10.1016\/j.jacig.2023.100117_bib4","doi-asserted-by":"crossref","first-page":"S73","DOI":"10.1016\/j.jaci.2009.11.017","article-title":"IgE, mast cells, basophils, and eosinophils","volume":"125","author":"Stone","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib5","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/s00281-016-0565-1","article-title":"IgE and mast cells in host defense against parasites and venoms","volume":"38","author":"Mukai","year":"2016","journal-title":"Semin Immunopathol"},{"key":"10.1016\/j.jacig.2023.100117_bib6","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.3389\/fimmu.2017.01749","article-title":"Tracing the origins of IgE, mast cells, and allergies by studies of wild animals","volume":"8","author":"Hellman","year":"2017","journal-title":"Front Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib7","series-title":"Allergy and asthma: the basics to best practices","first-page":"31","article-title":"Epidemiology of allergic diseases","author":"Doll","year":"2019"},{"key":"10.1016\/j.jacig.2023.100117_bib8","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1146\/annurev-genom-091212-153455","article-title":"Major histocompatibility complex genomics and human disease","volume":"14","author":"Trowsdale","year":"2013","journal-title":"Annu Rev Genomics Hum Genet"},{"key":"10.1016\/j.jacig.2023.100117_bib9","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1136\/thx.50.8.815","article-title":"HLA genetics and allergic disease","volume":"50","author":"Howell","year":"1995","journal-title":"Thorax"},{"key":"10.1016\/j.jacig.2023.100117_bib10","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0198-8859(92)90333-I","article-title":"Association between IgE response against Bet v I, the major allergen of birch pollen, and HLA-DRB alleles","volume":"33","author":"Fischer","year":"1992","journal-title":"Hum Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib11","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.jaci.2019.10.023","article-title":"Advances in asthma and allergic disease genetics: is bigger always better?","volume":"144","author":"Schoettler","year":"2019","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib12","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1038\/s41467-021-21381-3","article-title":"Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits","volume":"12","author":"Thareja","year":"2021","journal-title":"Nat Commun"},{"key":"10.1016\/j.jacig.2023.100117_bib13","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S1470-2045(21)00752-X","article-title":"Genetic predisposition to cancer across people of different ancestries in Qatar: a population-based, cohort study","volume":"23","author":"Saad","year":"2022","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.jacig.2023.100117_bib14","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.856497","article-title":"Human leukocyte antigen class II gene diversity tunes antibody repertoires to common pathogens","volume":"13","author":"Khan","year":"2022","journal-title":"Front Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib15","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1186\/s12889-015-2522-7","article-title":"The Qatar Biobank: background and methods","volume":"15","author":"Al Kuwari","year":"2015","journal-title":"BMC Public Health"},{"key":"10.1016\/j.jacig.2023.100117_bib16","article-title":"Distinct antibody repertoires against endemic human coronaviruses in children and adults","volume":"6","author":"Khan","year":"2021","journal-title":"JCI Insight"},{"key":"10.1016\/j.jacig.2023.100117_bib17","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2020.578523","article-title":"Host genetic variants potentially associated with SARS-CoV-2: a multi-population analysis","volume":"11","author":"Smatti","year":"2020","journal-title":"Front Genet"},{"key":"10.1016\/j.jacig.2023.100117_bib18","doi-asserted-by":"crossref","first-page":"4394","DOI":"10.1093\/bioinformatics\/btz235","article-title":"HLA\u2217LA-HLA typing from linearly projected graph alignments","volume":"35","author":"Dilthey","year":"2019","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jacig.2023.100117_bib19","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1002\/humu.23230","article-title":"HLA-HD: an accurate HLA typing algorithm for next-generation sequencing data","volume":"38","author":"Kawaguchi","year":"2017","journal-title":"Hum Mutat"},{"key":"10.1016\/j.jacig.2023.100117_bib22","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1086\/519795","article-title":"PLINK: a tool set for whole-genome association and population-based linkage analyses","volume":"81","author":"Purcell","year":"2007","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jacig.2023.100117_bib23","doi-asserted-by":"crossref","first-page":"2575","DOI":"10.1111\/all.14820","article-title":"Associations between specific IgE sensitization to 26 respiratory allergen molecules and HLA class II alleles in the EGEA cohort","volume":"76","author":"Gheerbrant","year":"2021","journal-title":"Allergy"},{"key":"10.1016\/j.jacig.2023.100117_bib24","first-page":"65","article-title":"A simple sequentially rejective multiple test procedure","volume":"6","author":"Holm","year":"1979","journal-title":"Scand J Stat"},{"key":"10.1016\/j.jacig.2023.100117_bib25","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1145\/1007730.1007735","article-title":"A study of the behavior of several methods for balancing machine learning training data","volume":"6","author":"Batista","year":"2004","journal-title":"ACM SIGKDD Explorations Newsletter"},{"key":"10.1016\/j.jacig.2023.100117_bib26","first-page":"559","article-title":"Imbalanced-learn: a Python toolbox to tackle the curse of imbalanced datasets in machine learning","volume":"18","author":"Lema\u00eetre","year":"2017","journal-title":"J Machine Learn Res"},{"key":"10.1016\/j.jacig.2023.100117_bib27","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.procs.2020.08.043","article-title":"A resampling method for imbalanced datasets considering noise and overlap","volume":"176","author":"Sasada","year":"2020","journal-title":"Procedia Comput Sci"},{"key":"10.1016\/j.jacig.2023.100117_bib28","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1089\/bio.2019.0067","article-title":"Conception, implementation, and integration of heterogenous information technology infrastructures in the Qatar Biobank","volume":"17","author":"Fthenou","year":"2019","journal-title":"Biopreserv Biobank"},{"key":"10.1016\/j.jacig.2023.100117_bib29","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1111\/j.1398-9995.1997.tb02523.x","article-title":"Prevalence of allergic sensitization to inhalant allergens among blood donors in Kuwait\u2014a desert country","volume":"52","author":"Ezeamuzie","year":"1997","journal-title":"Allergy"},{"key":"10.1016\/j.jacig.2023.100117_bib37","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s00251-021-01213-w","article-title":"Variation and expression of HLA-DPB1 gene in HBV infection","volume":"73","author":"Ou","year":"2021","journal-title":"Immunogenetics"},{"key":"10.1016\/j.jacig.2023.100117_bib38","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1016\/j.jid.2017.04.028","article-title":"RXRB is an MHC-encoded susceptibility gene associated with anti\u2013topoisomerase I antibody-positive systemic sclerosis","volume":"137","author":"Oka","year":"2017","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jacig.2023.100117_bib39","doi-asserted-by":"crossref","DOI":"10.1038\/srep24767","article-title":"Understanding of HLA-conferred susceptibility to chronic hepatitis B infection requires HLA genotyping-based association analysis","volume":"6","author":"Nishida","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.jacig.2023.100117_bib40","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1399-0039.2012.01872.x","article-title":"Associations between six classical HLA loci and rheumatoid arthritis: a comprehensive analysis","volume":"80","author":"Mitsunaga","year":"2012","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.jacig.2023.100117_bib41","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/tan.14575","article-title":"Association of HLA-DM and HLA class II genes with antibody response induced by inactivated Japanese encephalitis vaccine","volume":"99","author":"He","year":"2022","journal-title":"HLA"},{"key":"10.1016\/j.jacig.2023.100117_bib42","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.ajhg.2020.01.004","article-title":"Genome-wide association study identifies HLA-DPB1 as a significant risk factor for severe aplastic anemia","volume":"106","author":"Savage","year":"2020","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jacig.2023.100117_bib43","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1007\/s00262-015-1721-5","article-title":"Genetic susceptibility to cervical squamous cell carcinoma is associated with HLA-DPB1 polymorphisms in Taiwanese women","volume":"64","author":"Yang","year":"2015","journal-title":"Cancer Immunol Immunother"},{"key":"10.1016\/j.jacig.2023.100117_bib44","article-title":"Association of HLA-DPB1 with scleroderma and its clinical features in Chinese population","volume":"9","author":"Wang","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jacig.2023.100117_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2019.102372","article-title":"Fine mapping of the MHC region identifies major independent variants associated with Han Chinese primary biliary cholangitis","volume":"107","author":"Wang","year":"2020","journal-title":"J Autoimmun"},{"key":"10.1016\/j.jacig.2023.100117_bib46","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/cei.13571","article-title":"Behcet disease, new insights in disease associations and manifestations: a next-generation sequencing study","volume":"204","author":"Elfishawi","year":"2021","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib47","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1182\/blood.2020005395","article-title":"HLA loci predisposing to immune TTP in Japanese: potential role of the shared ADAMTS13 peptide bound to different HLA-DR","volume":"135","author":"Sakai","year":"2020","journal-title":"Blood"},{"key":"10.1016\/j.jacig.2023.100117_bib48","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0154393","article-title":"Protective role of HLA-DRB1\u221713:02 against microscopic polyangiitis and MPO-ANCA\u2013positive vasculitides in a Japanese population: a case\u2013control study","volume":"11","author":"Kawasaki","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jacig.2023.100117_bib49","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.humimm.2017.06.003","article-title":"Association between HLA-DQB1 alleles and susceptibility to coronary artery disease in Southern Han Chinese","volume":"78","author":"Xiong","year":"2017","journal-title":"Hum Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib50","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.644838","article-title":"High resolution haplotype analyses of classical HLA genes in families with multiple sclerosis highlights the role of HLA-DP alleles in disease susceptibility","volume":"12","author":"Osoegawa","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib51","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s11033-021-06855-3","article-title":"Contribution of HLA class II genes, DRB4\u221701:01, DRB1\u221707:01, and DQB1\u221703:03:2 to clinical features of vitiligo disease in Iranian population","volume":"49","author":"Ghaffarnia","year":"2022","journal-title":"Mol Biol Rep"},{"key":"10.1016\/j.jacig.2023.100117_bib52","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/iji.12216","article-title":"HLA class II susceptibility pattern for type 1 diabetes (T1D) in an Iranian population","volume":"42","author":"Kiani","year":"2015","journal-title":"Int J Immunogenet"},{"key":"10.1016\/j.jacig.2023.100117_bib53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12016-017-8662-z","article-title":"Pemphigus: a comprehensive review on pathogenesis, clinical presentation and novel therapeutic approaches","volume":"54","author":"Pollmann","year":"2018","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib54","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0201676","article-title":"An original Eurasian haplotype, HLA-DRB1\u221714:54-DQB1\u221705:03, influences the susceptibility to idiopathic achalasia","volume":"13","author":"Furuzawa-Carballeda","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.jacig.2023.100117_bib55","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1167\/iovs.62.9.19","article-title":"Next-generation HLA sequence analysis uncovers shared risk alleles between clinically distinct forms of childhood uveitis","volume":"62","author":"Wennink","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jacig.2023.100117_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.neulet.2021.136296","article-title":"Association of HLA-DRB1, DQA1 and DQB1 alleles and haplotype in Parkinson\u2019s disease from South India","volume":"765","author":"Pandi","year":"2021","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.jacig.2023.100117_bib57","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/1348-0421.12020","article-title":"HLA-DRB1 and HLA-DQB1 genes on susceptibility to and protection from allergic bronchopulmonary aspergillosis in patients with cystic fibrosis","volume":"57","author":"Muro","year":"2013","journal-title":"Microbiol Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib58","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1007\/s00439-013-1347-7","article-title":"HLA-DPB1\u221704:01 allele is associated with non-obstructive azoospermia in Japanese patients","volume":"132","author":"Jinam","year":"2013","journal-title":"Hum Genet"},{"key":"10.1016\/j.jacig.2023.100117_bib59","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-11148-6","article-title":"Principal contribution of HLA-DQ alleles, DQB1\u221706:04 and DQB1\u221703:01, to disease resistance against primary biliary cholangitis in a Japanese population","volume":"7","author":"Yasunami","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jacig.2023.100117_bib60","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.humimm.2018.10.013","article-title":"Protective association of HLA-DRB1\u221713:02, HLA-DRB1\u221704:06, and HLA-DQB1\u221706:04 alleles with cervical cancer in a Korean population","volume":"80","author":"Shim","year":"2019","journal-title":"Hum Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib61","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.1038\/s41598-021-82986-8","article-title":"Importance of HBsAg recognition by HLA molecules as revealed by responsiveness to different hepatitis B vaccines","volume":"11","author":"Nishida","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.jacig.2023.100117_bib62","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jaut.2016.04.007","article-title":"Differential HLA class I and class II associations in pemphigus foliaceus and pemphigus vulgaris patients from a prevalent Southeastern Brazilian region","volume":"72","author":"Brochado","year":"2016","journal-title":"J Autoimmun"},{"key":"10.1016\/j.jacig.2023.100117_bib63","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1111\/tan.12907","article-title":"Association of HLA alleles and haplotypes with CYP21A2 gene p.V282L mutation in the Croatian population","volume":"88","author":"Grubic","year":"2016","journal-title":"HLA"},{"key":"10.1016\/j.jacig.2023.100117_bib64","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1038\/s10038-018-0440-0","article-title":"Association of a single nucleotide polymorphism in TNIP1 with type-1 autoimmune hepatitis in the Japanese population","volume":"63","author":"Oka","year":"2018","journal-title":"J Hum Genet"},{"key":"10.1016\/j.jacig.2023.100117_bib65","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0099453","article-title":"Protective effect of the HLA-DRB1\u221713:02 allele in Japanese rheumatoid arthritis patients","volume":"9","author":"Oka","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jacig.2023.100117_bib66","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.rmed.2013.11.004","article-title":"Genetic susceptibility to multicase hypersensitivity pneumonitis is associated with the TNF-238 GG genotype of the promoter region and HLA-DRB1\u221704 bearing HLA haplotypes","volume":"108","author":"Falfan-Valencia","year":"2014","journal-title":"Respir Med"},{"key":"10.1016\/j.jacig.2023.100117_bib67","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1038\/ng.3143","article-title":"Variation at HLA-DRB1 is associated with resistance to enteric fever","volume":"46","author":"Dunstan","year":"2014","journal-title":"Nat Genet"},{"key":"10.1016\/j.jacig.2023.100117_bib68","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1080\/08820139.2020.1737539","article-title":"Breast cancer is associated with increased HLA-DRB1\u221711:01 and HLA-DRB1\u221710:01 allele frequency in a population of patients from Central Italy","volume":"49","author":"Aureli","year":"2020","journal-title":"Immunol Invest"},{"key":"10.1016\/j.jacig.2023.100117_bib69","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1080\/08820139.2021.1918708","article-title":"Influence of HLA class II alleles and DRB1-DQB1 haplotypes on rheumatoid arthritis susceptibility and autoantibody status in the Chinese Han population","volume":"51","author":"Wan","year":"2022","journal-title":"Immunol Invest"},{"key":"10.1016\/j.jacig.2023.100117_bib70","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1093\/brain\/awac090","article-title":"Clinical, serological and genetic predictors of response to immunotherapy in anti-IgLON5 disease","volume":"146","author":"Gruter","year":"2023","journal-title":"Brain"},{"key":"10.1016\/j.jacig.2023.100117_bib71","doi-asserted-by":"crossref","first-page":"4516","DOI":"10.4049\/jimmunol.1202445","article-title":"Differential binding of pyruvate dehydrogenase complex-E2 epitopes by DRB1\u221708:01 and DRB1\u221711:01 is predicted by their structural motifs and correlates with disease risk","volume":"190","author":"Chow","year":"2013","journal-title":"J Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib72","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.humimm.2013.04.020","article-title":"Associations of HLA-DRB1 and -DQB1 alleles with severe recurrent respiratory papillomatosis in Korean patients","volume":"74","author":"Song","year":"2013","journal-title":"Hum Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib73","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1002\/ijc.29285","article-title":"HLA-DRB1\u221713:01 allele in the genetic susceptibility to colorectal carcinoma","volume":"136","author":"Aureli","year":"2015","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jacig.2023.100117_bib74","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1002\/jmv.25531","article-title":"Association of HLA-DQB1\u221703:01 and DRB1\u221711:01 with spontaneous clearance of hepatitis C virus in Chinese Li ethnicity, an ethnic group genetically distinct from Chinese Han ethnicity and infected with unique HCV subtype","volume":"91","author":"Huang","year":"2019","journal-title":"J Med Virol"},{"key":"10.1016\/j.jacig.2023.100117_bib75","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.humimm.2019.09.001","article-title":"A single center study of protective and susceptible HLA alleles and haplotypes with end-stage renal disease in China","volume":"80","author":"Pan","year":"2019","journal-title":"Hum Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib76","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1080\/14397595.2018.1519148","article-title":"Human leukocyte antigen (HLA)-DRB1 allele polymorphisms and systemic sclerosis","volume":"29","author":"Xu","year":"2019","journal-title":"Mod Rheumatol"},{"key":"10.1016\/j.jacig.2023.100117_bib77","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/gene.2016.40","article-title":"The role of common protective alleles HLA-DRB1\u221713 among systemic autoimmune diseases","volume":"18","author":"Furukawa","year":"2017","journal-title":"Genes Immun"},{"key":"10.1016\/j.jacig.2023.100117_bib78","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s40246-020-00301-4","article-title":"Genetic risk factors for autoimmune hepatitis: implications for phenotypic heterogeneity and biomarkers for drug response","volume":"15","author":"Higuchi","year":"2021","journal-title":"Hum Genomics"},{"key":"10.1016\/j.jacig.2023.100117_bib79","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0087792","article-title":"Human leukocyte antigens and systemic lupus erythematosus: a protective role for the HLA-DR6 alleles DRB1\u221713:02 and \u221714:03","volume":"9","author":"Furukawa","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jacig.2023.100117_bib80","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.humimm.2020.12.007","article-title":"Critical amino acid variants in HLA-DRB1 allotypes in the development of Graves\u2019 disease and Hashimoto\u2019s thyroiditis in the Japanese population","volume":"82","author":"Katahira","year":"2021","journal-title":"Hum Immunol"},{"key":"10.1016\/j.jacig.2023.100117_bib81","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1007\/s00296-013-2686-3","article-title":"Association of HLA-DRB1\u221715:02 and DRB5\u221701:02 allele with the susceptibility to systemic sclerosis in Thai patients","volume":"33","author":"Louthrenoo","year":"2013","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.jacig.2023.100117_bib82","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1038\/jid.2011.231","article-title":"Black patients of African descent and HLA-DRB1\u221715:03 frequency overrepresented in epidermolysis bullosa acquisita","volume":"131","author":"Zumelzu","year":"2011","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jacig.2023.100117_bib83","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1111\/tme.12531","article-title":"HLA-DRB1\u221715:03 and HLA-DRB1\u221711: useful predictive alleles for alloantibody production in thalassemia patients","volume":"29","author":"Darvishi","year":"2019","journal-title":"Transfus Med"},{"key":"10.1016\/j.jacig.2023.100117_bib84","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2020.145179","article-title":"The role of HLA in Balkan endemic nephropathy","volume":"767","author":"Dittrich","year":"2021","journal-title":"Gene"},{"key":"10.1016\/j.jacig.2023.100117_bib85","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2020.102532","article-title":"Comprehensive meta-analysis reveals an association of the HLA-DRB1\u22171602 allele with autoimmune diseases mediated predominantly by autoantibodies","volume":"19","author":"Chen","year":"2020","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jacig.2023.100117_bib86","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1016\/j.jid.2017.11.027","article-title":"Amino acid variants of HLA-DRB1 confer susceptibility to dapsone hypersensitivity syndrome in addition to HLA-B\u221713:01","volume":"138","author":"Yue","year":"2018","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jacig.2023.100117_bib30","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1038\/ejhg.2013.13","article-title":"HLA-DQB1\u221702 and DQB1\u221706:03P are associated with peanut allergy","volume":"21","author":"Madore","year":"2013","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.jacig.2023.100117_bib31","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1038\/s41598-017-18241-w","article-title":"Genome-wide association study of self-reported food reactions in Japanese identifies shrimp and peach specific loci in the HLA-DR\/DQ gene region","volume":"8","author":"Khor","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.jacig.2023.100117_bib32","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-02893-w","article-title":"Targeted analysis of genomic regions enriched in African ancestry reveals novel classical HLA alleles associated with asthma in Southwestern Europeans","volume":"11","author":"Suarez-Pajes","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.jacig.2023.100117_bib33","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.tig.2020.01.008","article-title":"Advances in the evolutionary understanding of MHC polymorphism","volume":"36","author":"Radwan","year":"2020","journal-title":"Trends Genet"},{"key":"10.1016\/j.jacig.2023.100117_bib34","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1002\/ppul.25914","article-title":"The prevalence of asthma, allergic rhinitis, and eczema among school-aged children in Qatar: a Global Asthma Network Study","volume":"57","author":"Hammoudeh","year":"2022","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jacig.2023.100117_bib35","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/jhg.2016.141","article-title":"Comparison of exome-based HLA class I genotyping tools: identification of platform-specific genotyping errors","volume":"62","author":"Kiyotani","year":"2017","journal-title":"J Hum Genet"},{"key":"10.1016\/j.jacig.2023.100117_bib36","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/s41431-019-0559-2","article-title":"SweHLA: the high confidence HLA typing bio-resource drawn from 1000 Swedish genomes","volume":"28","author":"Nordin","year":"2020","journal-title":"Eur J Hum Genet"}],"container-title":["Journal of Allergy and Clinical Immunology: Global"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772829323000425?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772829323000425?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T13:11:41Z","timestamp":1757423501000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772829323000425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":84,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["S2772829323000425"],"URL":"https:\/\/doi.org\/10.1016\/j.jacig.2023.100117","relation":{},"ISSN":["2772-8293"],"issn-type":[{"type":"print","value":"2772-8293"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Associations between HLA class II alleles and IgE sensitization to allergens in the Qatar Biobank cohort","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology: Global","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacig.2023.100117","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology.","name":"copyright","label":"Copyright"}],"article-number":"100117"}}