{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:27:45Z","timestamp":1786991265724,"version":"build-2736575974"},"reference-count":20,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T00:00:00Z","timestamp":1726531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["jaci-global.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology: Global"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.jacig.2024.100346","type":"journal-article","created":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T21:22:28Z","timestamp":1726780948000},"page":"100346","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Distinguishing DRESS syndrome from drug rash and eosinophilia: Beyond RegiSCAR criteria"],"prefix":"10.1016","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5491-4698","authenticated-orcid":false,"given":"Grace","family":"Thompson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Trevenen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Vlaskovsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"Lucas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacig.2024.100346_bib1","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.clindermatol.2004.06.012","article-title":"Life-threatening acute adverse cutaneous drug reactions","volume":"23","author":"Wolf","year":"2005","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.jacig.2024.100346_bib2","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1111\/bjd.12501","article-title":"Drug reaction with eosinophilia and systemic symptoms (DRESS): an original multisystem adverse drug reaction. Results from the prospective RegiSCAR study","volume":"169","author":"Kardaun","year":"2013","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jacig.2024.100346_bib3","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s40257-018-00416-4","article-title":"Drug reaction with eosinophilia and systemic symptoms (DReSS): how far have we come?","volume":"20","author":"Mart\u00ednez-Cabriales","year":"2019","journal-title":"Am J Clin Dermatol"},{"key":"10.1016\/j.jacig.2024.100346_bib4","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1111\/j.1365-2133.2006.07704.x","article-title":"Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist?","volume":"156","author":"Kardaun","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jacig.2024.100346_bib5","doi-asserted-by":"crossref","first-page":"216","DOI":"10.4168\/aair.2014.6.3.216","article-title":"Comparison of diagnostic criteria and determination of prognostic factors for drug reaction with eosinophilia and systemic symptoms syndrome","volume":"6","author":"Kim","year":"2014","journal-title":"Allergy Asthma Immunol Res"},{"key":"10.1016\/j.jacig.2024.100346_bib6","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1111\/bjd.14986","article-title":"Is DRESS syndrome a single entity or within a spectrum of adverse reactions to drug?","volume":"175","author":"Ortonne","year":"2016","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jacig.2024.100346_bib7","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1111\/bjd.14704","article-title":"Overlap between maculopapular exanthema and drug reaction with eosinophilia and systemic symptoms among cutaneous adverse drug reactions in a dermatology ward","volume":"175","author":"Pinto Gouveia","year":"2016","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jacig.2024.100346_bib8","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1016\/j.jaci.2015.04.005","article-title":"Peripheral blood eosinophilia and hypersensitivity reactions among patients receiving outpatient parenteral antibiotics","volume":"136","author":"Blumenthal","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jacig.2024.100346_bib9","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.anai.2019.08.004","article-title":"Drug-induced severe cutaneous adverse reactions: determine the cause and prevention","volume":"123","author":"Zhang","year":"2019","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.jacig.2024.100346_bib10","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1111\/bcp.13096","article-title":"Eosinophilic drug reactions detected by a prospective pharmacovigilance programme in a tertiary hospital","volume":"83","author":"Ram\u00edrez","year":"2017","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.jacig.2024.100346_bib11","first-page":"65","article-title":"A simple sequentially rejective multiple test procedure","volume":"6","author":"Holm","year":"1979","journal-title":"Scand J Stat"},{"key":"10.1016\/j.jacig.2024.100346_bib12","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.jaad.2021.04.020","article-title":"Discriminating minor and major forms of drug reaction with eosinophilia and systemic symptoms: facial edema aligns to the severe phenotype","volume":"85","author":"Momen","year":"2021","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jacig.2024.100346_bib13","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1016\/j.jaip.2023.02.035","article-title":"Drug reaction with eosinophilia and systemic symptoms: a systematic review","volume":"11","author":"Awad","year":"2023","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jacig.2024.100346_bib14","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/j.1365-2133.2006.07284.x","article-title":"Variability in the clinical pattern of cutaneous side effects of drug with systemic symptoms: does a DRESS syndrome really exist?","volume":"155","author":"Peyriere","year":"2006","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jacig.2024.100346_bib15","first-page":"248","article-title":"Peripheral blood eosinophil counts predict the prognosis of drug eruptions","volume":"23","author":"Yang","year":"2013","journal-title":"J Investig Allergol Clin Immunol"},{"key":"10.1016\/j.jacig.2024.100346_bib16","first-page":"2008","article-title":"Role of peripheral eosinophilia in adverse cutaneous drug reactions","volume":"19","author":"Drago","year":"2015","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1016\/j.jacig.2024.100346_bib17","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1111\/ijd.17080","article-title":"A prospective observational study validating the CET score as a screening tool in suspected DRESS syndrome","volume":"63","author":"Singh","year":"2024","journal-title":"Int Journal Dermatol"},{"key":"10.1016\/j.jacig.2024.100346_bib18","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.601954","article-title":"Cross with caution: antibiotic cross-reactivity and co-reactivity patterns in severe cutanoeus adverse reactions","volume":"12","author":"Thompson","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.jacig.2024.100346_bib19","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1016\/j.jaci.2022.08.028","article-title":"Drug allergy: a 2022 practice parameter update","volume":"150","author":"Khan","year":"2022","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jacig.2024.100346_bib20","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.jaci.2020.04.056","article-title":"Cross-reactivity between vancomycin, teicoplanin, and telavancin in patients with HLA-A\u221732:01\u2013positive vancomycin-induced DRESS sharing an HLA class II haplotype","volume":"147","author":"Nakkam","year":"2021","journal-title":"J Allergy Clin Immunol"}],"container-title":["Journal of Allergy and Clinical Immunology: Global"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772829324001425?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772829324001425?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T12:50:50Z","timestamp":1731329450000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772829324001425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["S2772829324001425"],"URL":"https:\/\/doi.org\/10.1016\/j.jacig.2024.100346","relation":{},"ISSN":["2772-8293"],"issn-type":[{"value":"2772-8293","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Distinguishing DRESS syndrome from drug rash and eosinophilia: Beyond RegiSCAR criteria","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology: Global","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacig.2024.100346","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2024 Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology.","name":"copyright","label":"Copyright"}],"article-number":"100346"}}