{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T04:03:34Z","timestamp":1790136214646,"version":"4.0.1"},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:00:00Z","timestamp":1760572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jaci-global.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Allergy and Clinical Immunology: Global"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.jacig.2025.100583","type":"journal-article","created":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T05:58:46Z","timestamp":1761371926000},"page":"100583","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Cephalosporin allergy: R1 side-chain and penicillin cross-reactivity patterns in an Australian cohort"],"prefix":"10.1016","volume":"5","author":[{"given":"Brittany","family":"Stevenson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Klinken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Trevenen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Bourke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"Lucas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacig.2025.100583_bib1","doi-asserted-by":"crossref","first-page":"e1595","DOI":"10.1097\/PTS.0000000000000568","article-title":"Allergic reactions captured by voluntary reporting","volume":"17","author":"Blumenthal","year":"2021","journal-title":"J Patient Saf"},{"key":"10.1016\/j.jacig.2025.100583_bib2","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.jaip.2018.06.010","article-title":"Drug-induced anaphylaxis documented in electronic health records","volume":"7","author":"Dhopeshwarkar","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jacig.2025.100583_bib3","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/S1473-3099(14)70780-7","article-title":"Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data","volume":"14","author":"Van Boeckel","year":"2014","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jacig.2025.100583_bib4","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.ajog.2024.03.019","article-title":"Cefazolin as the mainstay for antibiotic prophylaxis in patients with a penicillin allergy in obstetrics and gynecology","volume":"231","author":"Dutra","year":"2024","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.jacig.2025.100583_bib5","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1177\/0310057X20964470","article-title":"Perioperative anaphylaxis: a five-year review in a tertiary paediatric hospital","volume":"49","author":"Toh","year":"2021","journal-title":"Anaesth Intensive Care"},{"key":"10.1016\/j.jacig.2025.100583_bib6","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1016\/j.jaip.2018.01.020","article-title":"Cross-reactivity and tolerability of cephalosporins in patients with IgE-mediated hypersensitivity to penicillins","volume":"6","author":"Romano","year":"2018","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jacig.2025.100583_bib7","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.jaip.2020.07.056","article-title":"Testing strategies and predictors for evaluating immediate and delayed reactions to cephalosporins","volume":"9","author":"Stone","year":"2021","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jacig.2025.100583_bib8","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1016\/j.jaip.2020.11.063","article-title":"Cephalosporin hypersensitivity: descriptive analysis, cross-reactivity, and risk factors","volume":"9","author":"Touati","year":"2021","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jacig.2025.100583_bib9","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jaip.2016.11.009","article-title":"World Allergy Organization Systemic Allergic Reaction Grading System: is a modification needed?","volume":"5","author":"Cox","year":"2017","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jacig.2025.100583_bib10","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1111\/all.12142","article-title":"Skin test concentrations for systemically administered drugs -- an ENDA\/EAACI Drug Allergy Interest Group position paper","volume":"68","author":"Brockow","year":"2013","journal-title":"Allergy"},{"key":"10.1016\/j.jacig.2025.100583_bib12","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.jaip.2017.08.027","article-title":"Cross-reactivity in beta-lactam allergy","volume":"6","author":"Zagursky","year":"2018","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jacig.2025.100583_bib13","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1159\/000519619","article-title":"Risk stratification as a predictive factor for cephalosporin allergy: a case-controlled study","volume":"183","author":"Suleyman","year":"2022","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jacig.2025.100583_bib14","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.jaci.2015.03.012","article-title":"IgE-mediated hypersensitivity to cephalosporins: cross-reactivity and tolerability of alternative cephalosporins","volume":"136","author":"Romano","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jacig.2025.100583_bib15","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.jaip.2014.11.002","article-title":"Improving the effectiveness of penicillin allergy de-labeling","volume":"3","author":"Bourke","year":"2015","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jacig.2025.100583_bib16","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1111\/all.14122","article-title":"Towards a more precise diagnosis of hypersensitivity to beta-lactams - an EAACI position paper","volume":"75","author":"Romano","year":"2020","journal-title":"Allergy"},{"key":"10.1016\/j.jacig.2025.100583_bib17","doi-asserted-by":"crossref","DOI":"10.1001\/jamasurg.2021.0021","article-title":"Assessment of the frequency of dual allergy to penicillins and cefazolin: a systematic review and meta-analysis","volume":"156","author":"Sousa-Pinto","year":"2021","journal-title":"JAMA Surg"},{"key":"10.1016\/j.jacig.2025.100583_bib18","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/anae.16185","article-title":"Penicillin cross-sensitivity in patients with confirmed peri-operative allergic hypersensitivity reactions to cefazolin: a retrospective observational study","volume":"79","author":"Pedersen","year":"2024","journal-title":"Anaesthesia"},{"key":"10.1016\/j.jacig.2025.100583_bib20","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/j.jaip.2024.12.043","article-title":"Resensitization\u2014should repeat testing be performed in patients undergoing penicillin allergy evaluations? A pro-con debate","volume":"13","author":"Belmont","year":"2025","journal-title":"J Allergy Clin Immunol Pract"}],"container-title":["Journal of Allergy and Clinical Immunology: Global"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772829325001845?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772829325001845?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T08:30:25Z","timestamp":1767861025000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772829325001845"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S2772829325001845"],"URL":"https:\/\/doi.org\/10.1016\/j.jacig.2025.100583","relation":{},"ISSN":["2772-8293"],"issn-type":[{"value":"2772-8293","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cephalosporin allergy: R1 side-chain and penicillin cross-reactivity patterns in an Australian cohort","name":"articletitle","label":"Article Title"},{"value":"Journal of Allergy and Clinical Immunology: Global","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacig.2025.100583","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology.","name":"copyright","label":"Copyright"}],"article-number":"100583"}}