{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T16:30:28Z","timestamp":1772814628029,"version":"3.50.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T00:00:00Z","timestamp":1435708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","lipidjournal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Lipidology"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1016\/j.jacl.2015.04.001","type":"journal-article","created":{"date-parts":[[2015,4,24]],"date-time":"2015-04-24T15:46:06Z","timestamp":1429890366000},"page":"553-558","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["High-density lipoprotein cholesterol, a protective or a risk factor for developing coronary heart disease? Tehran Lipid and Glucose Study"],"prefix":"10.1016","volume":"9","author":[{"given":"Seyed Saeed","family":"Hashemi Nazari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Shakiba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4956-1039","authenticated-orcid":false,"given":"Davood","family":"Khalili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farzad","family":"Hadaegh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Tohidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fereidoun","family":"Azizi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacl.2015.04.001_bib1","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/S0140-6736(08)61076-4","article-title":"Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries: a case-control study","volume":"372","author":"McQueen","year":"2008","journal-title":"Lancet"},{"issue":"9841","key":"10.1016\/j.jacl.2015.04.001_bib2","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/S0140-6736(12)60312-2","article-title":"Plasma HDL cholesterol and risk of myocardial infarction: a Mendelian Randomisation Study","volume":"380","author":"Voight","year":"2012","journal-title":"Lancet"},{"issue":"12","key":"10.1016\/j.jacl.2015.04.001_bib3","doi-asserted-by":"crossref","first-page":"E500","DOI":"10.1210\/jc.2010-0450","article-title":"Genetically elevated apolipoprotein A-I, high-density lipoprotein cholesterol levels, and risk of ischemic heart disease","volume":"95","author":"Haase","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jacl.2015.04.001_bib4","doi-asserted-by":"crossref","first-page":"E248","DOI":"10.1210\/jc.2011-1846","article-title":"LCAT, HDL cholesterol and ischemic cardiovasculardisease: a Mendelian Randomization Study of HDL cholesterol in 54,500 individuals","volume":"97","author":"Haase","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"issue":"9738","key":"10.1016\/j.jacl.2015.04.001_bib5","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0140-6736(10)60713-1","article-title":"HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial","volume":"376","author":"Ridker","year":"2010","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.jacl.2015.04.001_bib6","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.beem.2013.11.002","article-title":"Should low high-density lipoprotein cholesterol (HDL-C) be treated?","volume":"28","author":"Toth","year":"2014","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"issue":"3","key":"10.1016\/j.jacl.2015.04.001_bib7","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.beem.2013.11.001","article-title":"Emerging therapies for raising high-density lipoprotein cholesterol (HDL-C) and augmenting HDL particle functionality","volume":"28","author":"Barylski","year":"2014","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"issue":"25","key":"10.1016\/j.jacl.2015.04.001_bib8","doi-asserted-by":"crossref","first-page":"2881","DOI":"10.2174\/0929867321666140414103455","article-title":"Subfractions and subpopulations of HDL: an update","volume":"21","author":"Rizzo","year":"2014","journal-title":"Curr Med Chem"},{"issue":"7","key":"10.1016\/j.jacl.2015.04.001_bib9","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.tem.2014.05.005","article-title":"High-density lipoprotein subfractions: current views and clinical practice applications","volume":"25","author":"Martin","year":"2014","journal-title":"Trends Endocrinol Metab"},{"issue":"25","key":"10.1016\/j.jacl.2015.04.001_bib10","doi-asserted-by":"crossref","first-page":"2927","DOI":"10.2174\/0929867321666140303153829","article-title":"Can we change the functionality of HDL cholesterol with nonpharmacological and pharmacological agents?","volume":"21","author":"Dragan","year":"2014","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.jacl.2015.04.001_bib11","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.pharmthera.2012.12.001","article-title":"Inflammation alters HDL composition and function: implications for HDL-raising therapies","volume":"137","author":"Marsche","year":"2013","journal-title":"Pharmacol Ther"},{"issue":"9","key":"10.1016\/j.jacl.2015.04.001_bib12","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1016\/j.bbalip.2013.06.004","article-title":"Aging affects high-density lipoprotein composition and function","volume":"1831","author":"Holzer","year":"2013","journal-title":"Biochim Biophys Acta"},{"issue":"9","key":"10.1016\/j.jacl.2015.04.001_bib13","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1681\/ASN.2010111144","article-title":"Uremia alters HDL composition and function","volume":"22","author":"Holzer","year":"2011","journal-title":"J Am Soc Nephrol"},{"issue":"8","key":"10.1016\/j.jacl.2015.04.001_bib14","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1194\/jlr.M027367","article-title":"Psoriasis alters HDL composition and cholesterol efflux capacity","volume":"53","author":"Holzer","year":"2012","journal-title":"J Lipid Res"},{"issue":"25","key":"10.1016\/j.jacl.2015.04.001_bib15","doi-asserted-by":"crossref","first-page":"2853","DOI":"10.2174\/0929867321666140716090648","article-title":"Editorial: Current research, knowledge and controversies on high density lipoprotein","volume":"21","author":"Banach","year":"2014","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.jacl.2015.04.001_bib16","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1476-511X-9-6","article-title":"Lipid measures for prediction of incident cardiovascular disease in diabetic and nondiabetic adults: results of the 8.6 years follow-up of a population based cohort study","volume":"9","author":"Tohidi","year":"2010","journal-title":"Lipids Health Dis"},{"issue":"6","key":"10.1016\/j.jacl.2015.04.001_bib17","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1007\/s000380200008","article-title":"Cardiovascular risk factors in an Iranian urban population: Tehran Lipid and Glucose Study (phase 1)","volume":"47","author":"Azizi","year":"2002","journal-title":"Soz Praventivmed"},{"key":"10.1016\/j.jacl.2015.04.001_bib18","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1745-6215-10-5","article-title":"Prevention of non-communicable disease in population in nutrition transition: Tehran Lipid and Glucose Study phase II","volume":"10","author":"Azizi","year":"2009","journal-title":"Trials"},{"issue":"4","key":"10.1016\/j.jacl.2015.04.001_bib19","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1111\/j.1447-0756.2012.02050.x","article-title":"Factors associated with menopausal age in Iranian women: Tehran Lipid and Glucose Study","volume":"39","author":"Farahmand","year":"2013","journal-title":"J Obstet Gynaecol Res"},{"issue":"6","key":"10.1016\/j.jacl.2015.04.001_bib20","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1002\/sim.2699","article-title":"Choice of time scale and its effect on significance of predictors in longitudinal studies","volume":"26","author":"Pencina","year":"2007","journal-title":"Stat Med"},{"key":"10.1016\/j.jacl.2015.04.001_bib21","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1016\/j.metabol.2009.05.004","article-title":"Impaired protection against diabetes and coronary heart disease by high-density lipoproteins in Turks","volume":"58","author":"Onat","year":"2009","journal-title":"Metabolism"},{"key":"10.1016\/j.jacl.2015.04.001_bib22","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1093\/eurheartj\/ehs182","article-title":"Increasing high-density lipoprotein cholesterol by cholesteryl ester transfer protein-inhibition: a rocky road and lessons learned? The early demise of the dal-HEART programme","volume":"33","author":"Landmesser","year":"2012","journal-title":"Eur Heart J"},{"issue":"4","key":"10.1016\/j.jacl.2015.04.001_bib23","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.plipres.2012.03.003","article-title":"Dysfunctional HDL: a novel important diagnostic and therapeutic target in cardiovascular disease?","volume":"51","author":"Otocka-Kmiecik","year":"2012","journal-title":"Prog Lipid Res"},{"issue":"4","key":"10.1016\/j.jacl.2015.04.001_bib24","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s00592-014-0567-1","article-title":"Less but better: cardioprotective lipid profile of patients with GCK-MODY despite lower HDL cholesterol level","volume":"51","author":"Fendler","year":"2014","journal-title":"Acta Diabetol"},{"issue":"2","key":"10.1016\/j.jacl.2015.04.001_bib25","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.111.000232","article-title":"Apolipoprotein C-III as a potential modulator of the association between HDL-cholesterol and incident coronary heart disease","volume":"1","author":"Jensen","year":"2012","journal-title":"J Am Heart Assoc"},{"issue":"2","key":"10.1016\/j.jacl.2015.04.001_bib26","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0009-8981(91)90106-M","article-title":"Quantitation of serum apolipoprotein A-I, A-II, B, C-II, C-III and E in healthy Japanese by turbidimetric immunoassay: reference values, and age- and sex-related differences","volume":"199","author":"Noma","year":"1991","journal-title":"Clin Chim Acta"},{"issue":"3","key":"10.1016\/j.jacl.2015.04.001_bib27","doi-asserted-by":"crossref","first-page":"e52","DOI":"10.1371\/journal.pmed.0030052","article-title":"Association among race\/ethnicity, ApoC-III genotype, and lipids in HIV-1 infected individuals on antiretroviral therapy","volume":"3","author":"Foulkes","year":"2006","journal-title":"PLoS Med"},{"issue":"1","key":"10.1016\/j.jacl.2015.04.001_bib28","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ijcard.2007.12.019","article-title":"Can dysfunctional HDL explain high coronary artery disease risk in South Asians?","volume":"129","author":"Dodani","year":"2008","journal-title":"Int J Cardiol"},{"issue":"12","key":"10.1016\/j.jacl.2015.04.001_bib29","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1016\/j.amjcard.2004.08.040","article-title":"Comparison of levels of large and small high-density lipoprotein cholesterol in Asian Indian men compared to Caucasian men in the Framingham Offspring Study","volume":"94","author":"Bhalodkar","year":"2004","journal-title":"Am J Cardiol"},{"issue":"5","key":"10.1016\/j.jacl.2015.04.001_bib30","doi-asserted-by":"crossref","first-page":"870","DOI":"10.5114\/aoms.2014.46208","article-title":"Carotid intima media thickness and low high-density lipoprotein (HDL) in South Asian immigrants: could dysfunctional HDL be the missing link?","volume":"10","author":"Dodani","year":"2014","journal-title":"Arch Med Sci"},{"issue":"4","key":"10.1016\/j.jacl.2015.04.001_bib31","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1093\/oxfordjournals.aje.a010013","article-title":"Underestimation of risk associations due to regression dilution in long-term follow-up of prospective studies","volume":"150","author":"Clarke","year":"1999","journal-title":"Am J Epidemiol"}],"container-title":["Journal of Clinical Lipidology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933287415002032?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933287415002032?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,23]],"date-time":"2018-09-23T02:55:22Z","timestamp":1537671322000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1933287415002032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["S1933287415002032"],"URL":"https:\/\/doi.org\/10.1016\/j.jacl.2015.04.001","relation":{},"ISSN":["1933-2874"],"issn-type":[{"value":"1933-2874","type":"print"}],"subject":[],"published":{"date-parts":[[2015,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High-density lipoprotein cholesterol, a protective or a risk factor for developing coronary heart disease? Tehran Lipid and Glucose Study","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Lipidology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacl.2015.04.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 National Lipid Association. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}