{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:33:56Z","timestamp":1787319236930,"version":"build-2736575974"},"reference-count":60,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T00:00:00Z","timestamp":1670976000000},"content-version":"am","delay-in-days":469,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","lipidjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Lipidology"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.jacl.2021.08.003","type":"journal-article","created":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T01:51:23Z","timestamp":1629078683000},"page":"712-723","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Role of growth hormone in hepatic and intestinal triglyceride-rich lipoprotein metabolism"],"prefix":"10.1016","volume":"15","author":[{"given":"Marie","family":"Maraninchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasia","family":"Calabrese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8764-4700","authenticated-orcid":false,"given":"Juan-Patricio","family":"Nogueira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Castinetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9500-8598","authenticated-orcid":false,"given":"Julien","family":"Mancini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Mourre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e9a","family":"Pi\u00e9tri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"B\u00e9namo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9rique","family":"Albarel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Morange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanine","family":"Dupont-Roussel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Nicolay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8482-6691","authenticated-orcid":false,"given":"Thierry","family":"Brue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6000-5028","authenticated-orcid":false,"given":"Sophie","family":"B\u00e9liard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2176-3280","authenticated-orcid":false,"given":"Ren\u00e9","family":"Val\u00e9ro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jacl.2021.08.003_bib0001","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1161\/CIRCRESAHA.115.306249","article-title":"Triglyceride-rich lipoproteins and atherosclerotic cardiovascular disease: new insights from epidemiology, genetics, and biology","volume":"118","author":"Nordestgaard","year":"2016","journal-title":"Circ Res."},{"issue":"11","key":"10.1016\/j.jacl.2021.08.003_bib0002","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1093\/eurheartj\/ehr112","article-title":"Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management","volume":"32","author":"Chapman","year":"2011","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacl.2021.08.003_bib0003","doi-asserted-by":"crossref","first-page":"C2","DOI":"10.1093\/eurheartj\/suw009","article-title":"Current practice in identifying and treating cardiovascular risk, with a focus on residual risk associated with atherogenic dyslipidaemia","volume":"18","author":"Ferrari","year":"2016","journal-title":"Eur Heart J Suppl J Eur Soc Cardiol"},{"key":"10.1016\/j.jacl.2021.08.003_bib0004","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1567-5688(15)30001-5","article-title":"A review of the evidence on reducing macrovascular risk in patients with atherogenic dyslipidaemia: a report from an expert consensus meeting on the role of fenofibrate-statin combination therapy","volume":"19","author":"Aguiar","year":"2015","journal-title":"Atheroscler Suppl"},{"issue":"7","key":"10.1016\/j.jacl.2021.08.003_bib0005","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1161\/ATVBAHA.107.160192","article-title":"Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome","volume":"28","author":"Adiels","year":"2008","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"6","key":"10.1016\/j.jacl.2021.08.003_bib0006","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1161\/01.ATV.0000222015.76038.14","article-title":"Hyperinsulinemia is associated with increased production rate of intestinal apolipoprotein B-48-containing lipoproteins in humans","volume":"26","author":"Duez","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"6","key":"10.1016\/j.jacl.2021.08.003_bib0007","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0009-9120(03)00078-X","article-title":"Mechanisms of HDL lowering in insulin resistant, hypertriglyceridemic states: the combined effect of HDL triglyceride enrichment and elevated hepatic lipase activity","volume":"36","author":"Rashid","year":"2003","journal-title":"Clin Biochem"},{"issue":"3","key":"10.1016\/j.jacl.2021.08.003_bib0008","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1017\/S000711450774268X","article-title":"Dietary, physiological, genetic and pathological influences on postprandial lipid metabolism","volume":"98","author":"Lopez-Miranda","year":"2007","journal-title":"Br J Nutr"},{"issue":"3","key":"10.1016\/j.jacl.2021.08.003_bib0009","first-page":"195","article-title":"Cardiovascular risk factors in adult patients with growth hormone deficiency","volume":"129","author":"Ros\u00e9n","year":"1993","journal-title":"Acta Endocrinol"},{"issue":"7","key":"10.1016\/j.jacl.2021.08.003_bib0010","first-page":"2448","article-title":"Low density lipoprotein particle size in hypopituitary adults receiving conventional hormone replacement therapy","volume":"81","author":"O'Neal","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.jacl.2021.08.003_bib0011","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S1043-2760(98)00050-2","article-title":"Dyslipidaemia in adult growth hormone (GH) deficiency and the effect of GH replacement therapy: a review","volume":"9","author":"Christ","year":"1998","journal-title":"Trends Endocrinol Metab TEM"},{"issue":"8","key":"10.1016\/j.jacl.2021.08.003_bib0012","first-page":"2653","article-title":"Fasting and postprandial lipid abnormalities in hypopituitary women receiving conventional replacement therapy","volume":"82","author":"al-Shoumer","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"issue":"8710","key":"10.1016\/j.jacl.2021.08.003_bib0013","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0140-6736(90)91812-O","article-title":"Premature mortality due to cardiovascular disease in hypopituitarism","volume":"336","author":"Ros\u00e9n","year":"1990","journal-title":"Lancet Lond Engl"},{"issue":"1","key":"10.1016\/j.jacl.2021.08.003_bib0014","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1046\/j.1365-2265.1997.d01-1749.x","article-title":"Increased cerebrovascular mortality in patients with hypopituitarism","volume":"46","author":"B\u00fclow","year":"1997","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.jacl.2021.08.003_bib0015","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1146\/annurev-nutr-071714-034338","article-title":"New insights into the regulation of chylomicron production","volume":"35","author":"Dash","year":"2015","journal-title":"Annu Rev Nutr"},{"issue":"4","key":"10.1016\/j.jacl.2021.08.003_bib0016","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1097\/MOL.0b013e3283544956","article-title":"Determinants of VLDL-triglycerides production","volume":"23","author":"Nielsen","year":"2012","journal-title":"Curr Opin Lipidol"},{"issue":"Suppl 5","key":"10.1016\/j.jacl.2021.08.003_bib0017","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1159\/000191339","article-title":"The use of stable isotopes to unravel the hyperlipidemia of adult growth hormone deficiency","volume":"48","author":"Russell-Jones","year":"1997","journal-title":"Horm Res"},{"issue":"6","key":"10.1016\/j.jacl.2021.08.003_bib0018","first-page":"2010","article-title":"Abnormalities of very low density lipoprotein apolipoprotein B-100 metabolism contribute to the dyslipidaemia of adult growth hormone deficiency","volume":"82","author":"Cummings","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"issue":"8","key":"10.1016\/j.jacl.2021.08.003_bib0019","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/S0026-0495(99)90206-8","article-title":"Very-low-density lipoprotein apolipoprotein B100 kinetics in adult hypopituitarism","volume":"48","author":"Chrisoulidou","year":"1999","journal-title":"Metabolism"},{"issue":"1","key":"10.1016\/j.jacl.2021.08.003_bib0020","first-page":"307","article-title":"Effects of growth hormone (GH) replacement therapy on very low density lipoprotein apolipoprotein B100 kinetics in patients with adult GH deficiency: a stable isotope study","volume":"84","author":"Christ","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.jacl.2021.08.003_bib0021","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1053\/meta.2003.50061","article-title":"Effects of short- and long-term growth hormone replacement on lipoprotein composition and on very-low-density lipoprotein and low-density lipoprotein apolipoprotein B100 kinetics in growth hormone-deficient hypopituitary subjects","volume":"52","author":"Kearney","year":"2003","journal-title":"Metabolism"},{"issue":"5","key":"10.1016\/j.jacl.2021.08.003_bib0022","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0026-0495(00)80028-1","article-title":"Effects of growth hormone treatment on very-low density lipoprotein apolipoprotein B100 turnover in adult hypopituitarism","volume":"49","author":"Chrisoulidou","year":"2000","journal-title":"Metabolism"},{"issue":"5","key":"10.1016\/j.jacl.2021.08.003_bib0023","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1111\/j.1365-2265.2012.04416.x","article-title":"Postprandial triglyceride profile after a standardized oral fat load is altered in growth hormone (GH)-deficient adult patients and is not improved after short-term GH replacement therapy","volume":"77","author":"Perotti","year":"2012","journal-title":"Clin Endocrinol"},{"issue":"6","key":"10.1016\/j.jacl.2021.08.003_bib0024","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.2337\/diabetes.50.6.1402","article-title":"The effect of systemic versus portal insulin delivery in pancreas transplantation on insulin action and VLDL metabolism","volume":"50","author":"Carpentier","year":"2001","journal-title":"Diabetes"},{"issue":"7","key":"10.1016\/j.jacl.2021.08.003_bib0025","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/BF00280883","article-title":"Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man","volume":"28","author":"Matthews","year":"1985","journal-title":"Diabetologia"},{"issue":"9","key":"10.1016\/j.jacl.2021.08.003_bib0026","doi-asserted-by":"crossref","first-page":"3185","DOI":"10.1210\/jc.2012-2006","article-title":"Discontinuing long-term GH replacement therapy\u2013a randomized, placebo-controlled crossover trial in adult GH deficiency","volume":"97","author":"Filipsson","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"issue":"12","key":"10.1016\/j.jacl.2021.08.003_bib0027","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1016\/0026-0495(94)90001-9","article-title":"Lipids and apolipoproteins in growth hormone-deficient children during treatment","volume":"43","author":"Schaefer","year":"1994","journal-title":"Metabolism"},{"issue":"8","key":"10.1016\/j.jacl.2021.08.003_bib0028","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1111\/j.1651-2227.1996.tb14180.x","article-title":"Body composition, atherogenic risk factors and apolipoproteins following growth hormone treatment","volume":"85","author":"Hassan","year":"1996","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.jacl.2021.08.003_bib0029","series-title":"Sample Size Tables for Clinical Studies","author":"Machin","year":"2011"},{"issue":"12","key":"10.1016\/j.jacl.2021.08.003_bib0030","first-page":"4683","article-title":"Growth hormone (GH) treatment decreases postprandial remnant-like particle cholesterol concentration and improves endothelial function in adult-onset GH deficiency","volume":"85","author":"Twickler","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.jacl.2021.08.003_bib0031","doi-asserted-by":"crossref","first-page":"E122","DOI":"10.1210\/jc.2013-2477","article-title":"Plasma apolipoprotein B-48 transport in obese men: a new tracer kinetic study in the postprandial state","volume":"99","author":"Wong","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"10.1016\/j.jacl.2021.08.003_bib0032","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1194\/jlr.M600548-JLR200","article-title":"Evidence of increased secretion of apolipoprotein B-48-containing lipoproteins in subjects with type 2 diabetes","volume":"48","author":"Hogue","year":"2007","journal-title":"J Lipid Res"},{"issue":"8","key":"10.1016\/j.jacl.2021.08.003_bib0033","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1053\/meta.2002.33339","article-title":"Apolipoprotein B-100 kinetics in visceral obesity: associations with plasma apolipoprotein C-III concentration","volume":"51","author":"Chan","year":"2002","journal-title":"Metabolism"},{"issue":"10","key":"10.1016\/j.jacl.2021.08.003_bib0034","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1161\/01.ATV.0000032134.92180.41","article-title":"Early kinetic abnormalities of apoB-containing lipoproteins in insulin-resistant women with abdominal obesity","volume":"22","author":"Pont","year":"2002","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"5","key":"10.1016\/j.jacl.2021.08.003_bib0035","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1210\/jcem.85.5.6613","article-title":"Continuation of growth hormone (GH) therapy in GH-deficient patients during transition from childhood to adulthood: impact on insulin sensitivity and substrate metabolism","volume":"85","author":"N\u00f8rrelund","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"issue":"7","key":"10.1016\/j.jacl.2021.08.003_bib0036","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1053\/meta.2000.6738","article-title":"Regulation of lipoprotein lipase and hormone-sensitive lipase activity and gene expression in adipose and muscle tissue by growth hormone treatment during weight loss in obese patients","volume":"49","author":"Richelsen","year":"2000","journal-title":"Metabolism"},{"issue":"11","key":"10.1016\/j.jacl.2021.08.003_bib0037","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1016\/0026-0495(93)90197-V","article-title":"Effects of treatment with recombinant human growth hormone on insulin sensitivity and glucose metabolism in adults with growth hormone deficiency","volume":"42","author":"Fowelin","year":"1993","journal-title":"Metabolism"},{"issue":"4","key":"10.1016\/j.jacl.2021.08.003_bib0038","first-page":"975","article-title":"The effect of 3 months of recombinant human growth hormone (GH) therapy on insulin and glucose-mediated glucose disposal and insulin secretion in GH-deficient adults: a minimal model analysis","volume":"79","author":"O'Neal","year":"1994","journal-title":"J Clin Endocrinol Metab"},{"issue":"10","key":"10.1016\/j.jacl.2021.08.003_bib0039","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1161\/ATVBAHA.114.303849","article-title":"Effects of bariatric surgery on hepatic and intestinal lipoprotein particle metabolism in obese, nondiabetic humans","volume":"34","author":"Padilla","year":"2014","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"2","key":"10.1016\/j.jacl.2021.08.003_bib0040","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.jacl.2017.02.012","article-title":"Impact of bariatric surgery on apolipoprotein C-III levels and lipoprotein distribution in obese human subjects","volume":"11","author":"Maraninchi","year":"2017","journal-title":"J Clin Lipidol"},{"issue":"2","key":"10.1016\/j.jacl.2021.08.003_bib0041","doi-asserted-by":"crossref","first-page":"133","DOI":"10.2174\/1871529X11202020133","article-title":"Human apolipoprotein C-III - a new intrahepatic protein factor promoting assembly and secretion of very low density lipoproteins","volume":"12","author":"Yao","year":"2012","journal-title":"Cardiovasc Hematol Disord Drug Targets"},{"issue":"7","key":"10.1016\/j.jacl.2021.08.003_bib0042","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1111\/j.1464-5491.2009.02757.x","article-title":"Parallel increase of plasma apoproteins C-II and C-III in type 2 diabetic patients","volume":"26","author":"B\u00e9liard","year":"2009","journal-title":"Diabet Med J Br Diabet Assoc"},{"issue":"11","key":"10.1016\/j.jacl.2021.08.003_bib0043","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1016\/S0022-2275(20)39938-7","article-title":"Transcriptional regulation of the apoC-III gene by insulin in diabetic mice: correlation with changes in plasma triglyceride levels","volume":"35","author":"Chen","year":"1994","journal-title":"J Lipid Res"},{"issue":"3","key":"10.1016\/j.jacl.2021.08.003_bib0044","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1161\/01.ATV.0000203519.25116.54","article-title":"Apolipoproteins C-III and A-V as predictors of very-low-density lipoprotein triglyceride and apolipoprotein B-100 kinetics","volume":"26","author":"Chan","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"5","key":"10.1016\/j.jacl.2021.08.003_bib0045","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1172\/JCI116066","article-title":"Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles","volume":"90","author":"Aalto-Set\u00e4l\u00e4","year":"1992","journal-title":"J Clin Invest"},{"issue":"5","key":"10.1016\/j.jacl.2021.08.003_bib0046","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1172\/JCI112713","article-title":"Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI. Evidence that apolipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo","volume":"78","author":"Ginsberg","year":"1986","journal-title":"J Clin Invest"},{"issue":"6 Pt 1","key":"10.1016\/j.jacl.2021.08.003_bib0047","first-page":"G805","article-title":"Influence of apolipoprotein E on soluble and heparin-immobilized hepatic lipase","volume":"252","author":"Landis","year":"1987","journal-title":"Am J Physiol"},{"issue":"27","key":"10.1016\/j.jacl.2021.08.003_bib0048","doi-asserted-by":"crossref","first-page":"18259","DOI":"10.1016\/S0021-9258(18)55263-7","article-title":"Mechanisms of inhibition by apolipoprotein C of apolipoprotein E-dependent cellular metabolism of human triglyceride-rich lipoproteins through the low density lipoprotein receptor pathway","volume":"266","author":"Sehayek","year":"1991","journal-title":"J Biol Chem"},{"issue":"7","key":"10.1016\/j.jacl.2021.08.003_bib0049","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1161\/01.ATV.15.7.963","article-title":"Modulation of lipoprotein B binding to the LDL receptor by exogenous lipids and apolipoproteins CI, CII, CIII, and E","volume":"15","author":"Clavey","year":"1995","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"2","key":"10.1016\/j.jacl.2021.08.003_bib0050","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1677\/joe.0.1400203","article-title":"Growth hormone but not gonadal steroids influence lipoprotein lipase and hepatic lipase activity in hypophysectomized rats","volume":"140","author":"Vikman-Adolfsson","year":"1994","journal-title":"J Endocrinol"},{"issue":"3","key":"10.1016\/j.jacl.2021.08.003_bib0051","first-page":"936","article-title":"Growth hormone inhibits lipoprotein lipase activity in human adipose tissue","volume":"80","author":"Ottosson","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"10.1016\/j.jacl.2021.08.003_bib0052","doi-asserted-by":"crossref","first-page":"383","DOI":"10.2337\/db10-0763","article-title":"Effects of acute hyperglucagonemia on hepatic and intestinal lipoprotein production and clearance in healthy humans","volume":"60","author":"Xiao","year":"2011","journal-title":"Diabetes"},{"issue":"6","key":"10.1016\/j.jacl.2021.08.003_bib0053","doi-asserted-by":"crossref","first-page":"3356","DOI":"10.1210\/endo.130.6.1597147","article-title":"Effects of growth hormone on apolipoprotein-B (apoB) messenger ribonucleic acid editing, and apoB 48 and apoB 100 synthesis and secretion in the rat liver","volume":"130","author":"Sj\u00f6berg","year":"1992","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.jacl.2021.08.003_bib0054","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1172\/JCI118415","article-title":"Regulation of rat hepatic low density lipoprotein receptors. In vivo stimulation by growth hormone is not mediated by insulin-like growth factor I","volume":"97","author":"Rudling","year":"1996","journal-title":"J Clin Invest"},{"issue":"4","key":"10.1016\/j.jacl.2021.08.003_bib0055","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1210\/endo.135.4.7925103","article-title":"Insulin-like growth factor-I and growth hormone have different effects on serum lipoproteins and secretion of lipoproteins from cultured rat hepatocytes","volume":"135","author":"Sj\u00f6berg","year":"1994","journal-title":"Endocrinology"},{"issue":"19","key":"10.1016\/j.jacl.2021.08.003_bib0056","doi-asserted-by":"crossref","first-page":"8851","DOI":"10.1073\/pnas.90.19.8851","article-title":"Loss of resistance to dietary cholesterol in the rat after hypophysectomy: importance of the presence of growth hormone for hepatic low density lipoprotein-receptor expression","volume":"90","author":"Rudling","year":"1993","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"15","key":"10.1016\/j.jacl.2021.08.003_bib0057","doi-asserted-by":"crossref","first-page":"6983","DOI":"10.1073\/pnas.89.15.6983","article-title":"Importance of growth hormone for the induction of hepatic low density lipoprotein receptors","volume":"89","author":"Rudling","year":"1992","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5","key":"10.1016\/j.jacl.2021.08.003_bib0058","doi-asserted-by":"crossref","first-page":"E1023","DOI":"10.1152\/ajpendo.00260.2002","article-title":"Interaction between growth hormone and insulin in the regulation of lipoprotein metabolism in the rat","volume":"283","author":"Frick","year":"2002","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"18","key":"10.1016\/j.jacl.2021.08.003_bib0059","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1161\/CIRCULATIONAHA.107.739888","article-title":"Both intestinal and hepatic lipoprotein production are stimulated by an acute elevation of plasma free fatty acids in humans","volume":"117","author":"Duez","year":"2008","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.jacl.2021.08.003_bib0060","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1161\/01.ATV.13.5.629","article-title":"Substrate delivery as a determinant of hepatic apoB secretion","volume":"13","author":"Sniderman","year":"1993","journal-title":"Arterioscler Thromb J Vasc Biol"}],"container-title":["Journal of Clinical Lipidology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933287421001239?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933287421001239?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T13:37:02Z","timestamp":1761831422000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1933287421001239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":60,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S1933287421001239"],"URL":"https:\/\/doi.org\/10.1016\/j.jacl.2021.08.003","relation":{},"ISSN":["1933-2874"],"issn-type":[{"value":"1933-2874","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of growth hormone in hepatic and intestinal triglyceride-rich lipoprotein metabolism","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Lipidology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacl.2021.08.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 National Lipid Association. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}