{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T11:00:31Z","timestamp":1793530831589,"version":"4.5.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:00:00Z","timestamp":1742342400000},"content-version":"am","delay-in-days":443,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["lipidjournal.com","clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Lipidology"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.jacl.2023.10.006","type":"journal-article","created":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T06:53:02Z","timestamp":1697266382000},"page":"3-10","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Association between remnant cholesterol and incident atherosclerotic cardiovascular disease, heart failure, and atrial fibrillation"],"prefix":"10.1016","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3357-1809","authenticated-orcid":false,"given":"Hayato","family":"Tada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidehiro","family":"Kaneko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9406-4691","authenticated-orcid":false,"given":"Yuta","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4818-3347","authenticated-orcid":false,"given":"Norifumi","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1889-9291","authenticated-orcid":false,"given":"Katsuhito","family":"Fujiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Morita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6645-6404","authenticated-orcid":false,"given":"Junya","family":"Ako","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichi","family":"Node","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuaki","family":"Takeji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1540-4417","authenticated-orcid":false,"given":"Masayuki","family":"Takamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Yasunaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Issei","family":"Komuro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.jacl.2023.10.006_bib0001","doi-asserted-by":"crossref","first-page":"e93","DOI":"10.1161\/CIR.0000000000001123","article-title":"American heart association council on epidemiology and prevention statistics committee and stroke statistics subcommittee. Heart disease and stroke statistics-2023 update: a report from the American Heart Association","volume":"147","author":"Tsao","year":"2023","journal-title":"Circulation."},{"issue":"18","key":"10.1016\/j.jacl.2023.10.006_bib0002","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1016\/j.jacc.2023.01.049","article-title":"Heart failure with preserved ejection fraction: JACC scientific statement","volume":"81","author":"Borlaug","year":"2023","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacl.2023.10.006_bib0003","doi-asserted-by":"crossref","unstructured":"Ofstad A.P., Brunborg C., Johansen O.E., et al. Development of a tool to predict the risk of incident heart failure in a general population: the HUNT for HF risk score. ESC Heart Fail. 2023 May 29. doi: 10.1002\/ehf2.14390. Epub ahead of print. PMID: 37248650.","DOI":"10.1002\/ehf2.14390"},{"key":"10.1016\/j.jacl.2023.10.006_bib0004","doi-asserted-by":"crossref","DOI":"10.1253\/circj.CJ-22-0805","article-title":"Impact of cardiovascular disease on the death certificate diagnosis of heart failure, ischemic heart disease, and cerebrovascular disease - The Japan public health center-based prospective study","author":"Saito","year":"2023","journal-title":"Circ J"},{"issue":"9","key":"10.1016\/j.jacl.2023.10.006_bib0005","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.jacc.2015.06.1314","article-title":"Incidence of atrial fibrillation and relationship with cardiovascular events, heart failure, and mortality: a community-based study from the netherlands","volume":"66","author":"Vermond","year":"2015","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.jacl.2023.10.006_bib0006","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1093\/europace\/euac123","volume":"25","author":"Savelieva","year":"2023","journal-title":"Europace"},{"issue":"8","key":"10.1016\/j.jacl.2023.10.006_bib0007","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1253\/circj.CJ-22-0180","article-title":"Association of concomitant coronary artery disease with cardiovascular events in patients with atrial fibrillation - the fushimi AF registry","volume":"86","author":"Masunaga","year":"2022","journal-title":"Circ J"},{"issue":"3","key":"10.1016\/j.jacl.2023.10.006_bib0008","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1002\/ehf2.14355","article-title":"Systematic review of sodium-glucose cotransporter 2 inhibitors: a hopeful prospect in tackling heart failure-related events","volume":"10","author":"Aziri","year":"2023","journal-title":"ESC Heart Fail"},{"issue":"1","key":"10.1016\/j.jacl.2023.10.006_bib0009","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.jacbts.2022.05.010","article-title":"Neprilysin inhibitors in heart failure: the science, mechanism of action, clinical studies, and unanswered questions","volume":"8","author":"Bozkurt","year":"2022","journal-title":"JACC Basic Transl Sci"},{"key":"10.1016\/j.jacl.2023.10.006_bib0010","doi-asserted-by":"crossref","first-page":"j5058","DOI":"10.1136\/bmj.j5058","article-title":"Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis","volume":"359","author":"L\u00f3pez-L\u00f3pez","year":"2017","journal-title":"BMJ"},{"issue":"3","key":"10.1016\/j.jacl.2023.10.006_bib0011","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1038\/s41569-020-00451-x","article-title":"Catheter ablation for atrial fibrillation: current indications and evolving technologies","volume":"18","author":"Parameswaran","year":"2021","journal-title":"Nat Rev Cardiol"},{"issue":"6","key":"10.1016\/j.jacl.2023.10.006_bib0012","doi-asserted-by":"crossref","first-page":"489","DOI":"10.5551\/jat.RV17040","article-title":"Low-density lipoprotein cholesterol level cannot be too low: considerations from clinical trials","volume":"27","author":"Tada","year":"2020","journal-title":"Human Genetics, and Biology. J Atheroscler Thromb."},{"issue":"3","key":"10.1016\/j.jacl.2023.10.006_bib0013","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1253\/circj.CJ-19-0981","article-title":"Fasting and non-fasting triglycerides and risk of cardiovascular events in diabetic patients under statin therapy","volume":"84","author":"Tada","year":"2020","journal-title":"Circ J"},{"key":"10.1016\/j.jacl.2023.10.006_bib0014","article-title":"Association between remnant cholesterol and heart failure: a prospective cohort study","volume":"9","author":"Liu","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.jacl.2023.10.006_bib0015","first-page":"qcad030","article-title":"Relationship between remnant cholesterol and risk of heart failure in participants with diabetes mellitus","author":"Wang","year":"2023","journal-title":"Eur Heart J Qual Care Clin Outcomes"},{"key":"10.1016\/j.jacl.2023.10.006_bib0016","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cca.2018.12.014","article-title":"Remnant lipoproteins and atherosclerotic cardiovascular disease","volume":"490","author":"Tada","year":"2019","journal-title":"Clin Chim Acta"},{"issue":"24","key":"10.1016\/j.jacl.2023.10.006_bib0017","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.1093\/eurheartj\/ehaa172","article-title":"Triglycerides and remnant cholesterol associated with risk of aortic valve stenosis: mendelian randomization in the Copenhagen General Population Study","volume":"41","author":"Kaltoft","year":"2020","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacl.2023.10.006_bib0018","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.1042729","article-title":"The critical issue linking lipids and inflammation: clinical utility of stopping oxidative stress","volume":"9","author":"Bale","year":"2022","journal-title":"Front Cardiovasc Med"},{"issue":"23","key":"10.1016\/j.jacl.2023.10.006_bib0019","doi-asserted-by":"crossref","first-page":"2712","DOI":"10.1016\/j.jacc.2020.10.008","article-title":"Remnant Cholesterol, Not LDL Cholesterol, Is Associated With Incident Cardiovascular Disease","volume":"76","author":"Casta\u00f1er","year":"2020","journal-title":"J Am Coll Cardiol"},{"issue":"23","key":"10.1016\/j.jacl.2023.10.006_bib0020","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1161\/CIRCULATIONAHA.120.052624","article-title":"Association of blood pressure classification using the 2017 American college of cardiology\/American heart association blood pressure guideline with risk of heart failure and atrial fibrillation","volume":"143","author":"Kaneko","year":"2021","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.jacl.2023.10.006_bib0021","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.122.027684","article-title":"Age-dependent association between modifiable risk factors and incident cardiovascular disease","volume":"12","author":"Kaneko","year":"2023","journal-title":"J Am Heart Assoc"},{"issue":"5","key":"10.1016\/j.jacl.2023.10.006_bib0022","doi-asserted-by":"crossref","first-page":"455","DOI":"10.5551\/jat.63519","article-title":"Association of low-density lipoprotein cholesterol with risk of coronary heart disease and stroke among middle-aged Japanese workers: an analysis using inverse probability weighting","volume":"30","author":"Al-Shoaibi","year":"2023","journal-title":"J Atheroscler Thromb"},{"issue":"1","key":"10.1016\/j.jacl.2023.10.006_bib0023","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1093\/clinchem\/hvaa296","article-title":"Triglyceride-rich lipoprotein remnants and cardiovascular disease","volume":"67","author":"Duran","year":"2021","journal-title":"Clin Chem"},{"issue":"4","key":"10.1016\/j.jacl.2023.10.006_bib0024","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.jacc.2012.08.1026","article-title":"Remnant cholesterol as a causal risk factor for ischemic heart disease","volume":"61","author":"Varbo","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacl.2023.10.006_bib0025","article-title":"Predictive value of remnant cholesterol level for all-cause mortality in heart failure patients","volume":"10","author":"Zhao","year":"2023","journal-title":"Front Cardiovasc Med"},{"issue":"24","key":"10.1016\/j.jacl.2023.10.006_bib0026","doi-asserted-by":"crossref","first-page":"2941","DOI":"10.1016\/j.jacc.2017.04.051","article-title":"CHARGE extracoronary calcium working group. association of triglyceride-related genetic variants with mitral annular calcification","volume":"69","author":"Afshar","year":"2017","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.jacl.2023.10.006_bib0027","doi-asserted-by":"crossref","first-page":"9597","DOI":"10.1038\/s41598-022-13773-2","article-title":"Association between serum apolipoprotein B and atrial fibrillation: a case-control study","volume":"12","author":"Zhong","year":"2022","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.jacl.2023.10.006_bib0028","doi-asserted-by":"crossref","first-page":"73","DOI":"10.12997\/jla.2023.12.1.73","article-title":"Evaluation of the paradoxical association between lipid levels and incident atrial fibrillation according to statin usage: a nationwide cohort study","volume":"12","author":"Ahn","year":"2023","journal-title":"J Lipid Atheroscler"},{"issue":"5","key":"10.1016\/j.jacl.2023.10.006_bib0029","doi-asserted-by":"crossref","first-page":"515","DOI":"10.5551\/jat.63574","article-title":"Lipid levels and new-onset atrial fibrillation in patients with acute myocardial infarction","volume":"30","author":"Liu","year":"2023","journal-title":"J Atheroscler Thromb"},{"issue":"4","key":"10.1016\/j.jacl.2023.10.006_bib0030","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1085\/jgp.115.4.405","article-title":"Membrane cholesterol content modulates activation of volume-regulated anion current in bovine endothelial cells","volume":"115","author":"Levitan","year":"2000","journal-title":"J Gen Physiol"},{"issue":"11","key":"10.1016\/j.jacl.2023.10.006_bib0031","doi-asserted-by":"crossref","first-page":"7443","DOI":"10.1074\/jbc.275.11.7443","article-title":"Differential targeting of Shaker-like potassium channels to lipid rafts","volume":"275","author":"Martens","year":"2000","journal-title":"J Biol Chem"},{"issue":"Pt 3","key":"10.1016\/j.jacl.2023.10.006_bib0032","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1113\/jphysiol.2007.134809","article-title":"Membrane cholesterol modulates Kv1.5 potassium channel distribution and function in rat cardiomyocytes","volume":"582","author":"Abi-Char","year":"2007","journal-title":"J Physiol"},{"issue":"6","key":"10.1016\/j.jacl.2023.10.006_bib0033","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1161\/CIRCEP.115.002751","article-title":"Dyscholesterolemia protects against ischemia-induced ventricular arrhythmias","volume":"8","author":"Baartscheer","year":"2015","journal-title":"Circ Arrhythm Electrophysiol"},{"issue":"25","key":"10.1016\/j.jacl.2023.10.006_bib0034","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1161\/CIRCULATIONAHA.121.055654","article-title":"Effect of long-term marine \u0277-3 fatty acids supplementation on the risk of atrial fibrillation in randomized controlled trials of cardiovascular outcomes: a systematic review and meta-analysis","volume":"144","author":"Gencer","year":"2021","journal-title":"Circulation"},{"issue":"42","key":"10.1016\/j.jacl.2023.10.006_bib0035","doi-asserted-by":"crossref","first-page":"4324","DOI":"10.1093\/eurheartj\/ehab432","article-title":"Remnant cholesterol predicts cardiovascular disease beyond LDL and ApoB: a primary prevention study","volume":"42","author":"Quispe","year":"2021","journal-title":"Eur Heart J"},{"issue":"10","key":"10.1016\/j.jacl.2023.10.006_bib0036","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.je.2016.09.009","article-title":"Validity of diagnoses, procedures, and laboratory data in Japanese administrative data","volume":"27","author":"Yamana","year":"2017","journal-title":"J Epidemiol"},{"issue":"14","key":"10.1016\/j.jacl.2023.10.006_bib0037","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1161\/CIRCULATIONAHA.108.823112","article-title":"Japan Arteriosclerosis Longitudinal Study (JALS) Group. Four blood pressure indexes and the risk of stroke and myocardial infarction in Japanese men and women: a meta-analysis of 16 cohort studies","volume":"119","author":"Miura","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.jacl.2023.10.006_bib0038","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.ijcard.2016.07.222","article-title":"Association between mortality and incidence rates of coronary heart disease and stroke: the Japan Public Health Center-based prospective (JPHC) study","volume":"222","author":"Saito","year":"2016","journal-title":"Int J Cardiol"}],"container-title":["Journal of Clinical Lipidology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933287423002933?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933287423002933?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T12:48:55Z","timestamp":1710938935000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1933287423002933"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["S1933287423002933"],"URL":"https:\/\/doi.org\/10.1016\/j.jacl.2023.10.006","relation":{},"ISSN":["1933-2874"],"issn-type":[{"value":"1933-2874","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between remnant cholesterol and incident atherosclerotic cardiovascular disease, heart failure, and atrial fibrillation","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Lipidology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacl.2023.10.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 National Lipid Association. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}