{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T15:27:02Z","timestamp":1790263622828,"version":"4.1.0"},"reference-count":128,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","lipidjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Lipidology"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.jacl.2025.05.015","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T11:13:11Z","timestamp":1748862791000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Lipoprotein X \u2013 Pathophysiology, diagnosis, and management"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5254-4067","authenticated-orcid":false,"given":"Dinesh K.","family":"Kalra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Shotwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhimanyu","family":"Garg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0208-5154","authenticated-orcid":false,"given":"P. Barton","family":"Duell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2815-4816","authenticated-orcid":false,"given":"Don P.","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7021-7622","authenticated-orcid":false,"given":"Seth S.","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel E.","family":"Soffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert S.","family":"Rosenson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9071-3287","authenticated-orcid":false,"given":"Michael D.","family":"Shapiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7810-4024","authenticated-orcid":false,"given":"Zahid","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Underberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9417-6370","authenticated-orcid":false,"given":"Laurence","family":"Sperling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6824-9134","authenticated-orcid":false,"given":"Saeed A.","family":"Jortani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Remaley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0001","doi-asserted-by":"crossref","first-page":"564","DOI":"10.3390\/molecules29030564","article-title":"A high-throughput NMR method for lipoprotein-X quantification","volume":"29","author":"Garcia","year":"2024","journal-title":"Molecules (Basel, Switzerland)"},{"issue":"8","key":"10.1016\/j.jacl.2025.05.015_bib0002","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.bbalip.2016.04.016","article-title":"Lipid profiling of lipoprotein X: implications for dyslipidemia in cholestasis","volume":"1861","author":"Heimerl","year":"2016","journal-title":"Biochimica et Biophysica Acta (BBA) - Mol Cell Biol Lipids"},{"issue":"6","key":"10.1016\/j.jacl.2025.05.015_bib0003","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1016\/S0021-9258(18)71873-5","article-title":"Isolation, chemical characterization, and biophysical properties of three different abnormal lipoproteins: LP-X1, LP-X2, and LP-X3","volume":"252","author":"Patsch","year":"1977","journal-title":"J Biol Chem"},{"issue":"7","key":"10.1016\/j.jacl.2025.05.015_bib0004","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1172\/JCI106085","article-title":"A lipoprotein characterizing obstructive jaundice. I. Method for quantitative separation and identification of lipoproteins in jaundiced subjects","volume":"48","author":"Seidel","year":"1969","journal-title":"J Clin Investig"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0005","first-page":"31","article-title":"Lipoprotein-X","volume":"11","author":"Narayanan","year":"1979","journal-title":"CRC Crit Rev Clin Lab Sci"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0006","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1432-1033.1977.tb11654.x","article-title":"The lipid bilayer structure of the abnormal human plasma lipoprotein X. An X-ray small-angle-scattering study","volume":"77","author":"Laggner","year":"1977","journal-title":"Eur J Biochem"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0007","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.numecd.2018.09.006","article-title":"Lipoprotein-X fifty years after its original discovery","volume":"29","author":"Fellin","year":"2019","journal-title":"Nutr Metab Cardiovasc Dis"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0008","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1172\/JCI111504","article-title":"Role of lipoprotein-X in the pathogenesis of cholestatic hypercholesterolemia. Uptake of lipoprotein-X and its effect on 3-hydroxy-3-methylglutaryl coenzyme A reductase and chylomicron remnant removal in human fibroblasts, lymphocytes, and in the rat","volume":"74","author":"Walli","year":"1984","journal-title":"J Clin Investig"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0009","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.atherosclerosis.2006.11.036","article-title":"Primary biliary cirrhosis, hyperlipidemia, and atherosclerotic risk: a systematic review","volume":"194","author":"Sorokin","year":"2007","journal-title":"Atherosclerosis"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0010","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1136\/gut.51.2.265","article-title":"Hyperlipidaemic state and cardiovascular risk in primary biliary cirrhosis","volume":"51","author":"Longo","year":"2002","journal-title":"Gut"},{"issue":"4","key":"10.1016\/j.jacl.2025.05.015_bib0011","doi-asserted-by":"crossref","first-page":"93","DOI":"10.4254\/wjh.v3.i4.93","article-title":"Asymptomatic primary biliary cirrhosis is not associated with increased frequency of cardiovascular disease","volume":"3","author":"Doycheva","year":"2011","journal-title":"World J Hepatol"},{"issue":"11","key":"10.1016\/j.jacl.2025.05.015_bib0012","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1194\/jlr.M400229-JLR200","article-title":"Lipoprotein-X reduces LDL atherogenicity in primary biliary cirrhosis by preventing LDL oxidation","volume":"45","author":"Chang","year":"2004","journal-title":"J Lipid Res"},{"issue":"12","key":"10.1016\/j.jacl.2025.05.015_bib0013","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1136\/gut.11.12.1035","article-title":"Occurrence of an abnormal lipoprotein in patients with liver disease","volume":"11","author":"Ross","year":"1970","journal-title":"Gut"},{"issue":"4","key":"10.1016\/j.jacl.2025.05.015_bib0014","first-page":"369","article-title":"Lecithin\u2014Cholesterol acyltransferase and the lipoprotein abnormalities of obstructive jaundice","volume":"54","author":"Agorastos","year":"1978","journal-title":"Clin Sci Mol Med"},{"issue":"4","key":"10.1016\/j.jacl.2025.05.015_bib0015","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/S0950-351X(05)80080-1","article-title":"5 Dyslipoproteinaemia of liver disease","volume":"4","author":"Paul Miller","year":"1990","journal-title":"Bailli\u00e8re\u2019s Clin Endocrinol Metab"},{"issue":"Pt 2","key":"10.1016\/j.jacl.2025.05.015_bib0016","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1258\/acb.2012.012148","article-title":"Lipoprotein X in a patient with cholestasis and hypertriglyceridaemia","volume":"50","author":"Stepien","year":"2013","journal-title":"Ann Clin Biochem"},{"issue":"5","key":"10.1016\/j.jacl.2025.05.015_bib0017","first-page":"371","article-title":"Biochemistry and clinical relevance of lipoprotein X","volume":"14","author":"Narayanan","year":"1984","journal-title":"Ann Clin Lab Sci"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0018","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1042\/bj1570401","article-title":"Investigation of the abnormal low-density lipoproteins occurring in patients with obstructive jaundice","volume":"157","author":"Kostner","year":"1976","journal-title":"Biochem J"},{"issue":"6","key":"10.1016\/j.jacl.2025.05.015_bib0019","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.aohep.2019.07.006","article-title":"Patterns of serum lipids derangements and cardiovascular risk assessment in patients with primary biliary cholangitis","volume":"18","author":"Loaeza-Del Castillo","year":"2019","journal-title":"Ann Hepatol"},{"issue":"15","key":"10.1016\/j.jacl.2025.05.015_bib0020","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1056\/NEJMc071467","article-title":"Hypercholesterolemia in primary biliary cirrhosis","volume":"357","author":"Su","year":"2007","journal-title":"N Engl J Med"},{"issue":"11","key":"10.1016\/j.jacl.2025.05.015_bib0021","doi-asserted-by":"crossref","first-page":"2784","DOI":"10.1111\/j.1572-0241.2008.02092.x","article-title":"Risk of cardiovascular and cerebrovascular events in primary biliary cirrhosis: a population-based cohort study","volume":"103","author":"Solaymani-Dodaran","year":"2008","journal-title":"Am J Gastroenterol"},{"issue":"11","key":"10.1016\/j.jacl.2025.05.015_bib0022","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1172\/JCI105676","article-title":"Plasma lipoproteins in liver disease. I. Immunologically distinct low-density lipoproteins in patients with biliary obstruction","volume":"46","author":"Switzer","year":"1967","journal-title":"J Clin Invest"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0023","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0009-8981(88)90265-3","article-title":"Apolipoprotein measurements in clinical biochemistry and their utility vis-a-vis conventional assays","volume":"178","author":"Bachorik","year":"1988","journal-title":"Clin Chim Acta"},{"issue":"22","key":"10.1016\/j.jacl.2025.05.015_bib0024","doi-asserted-by":"crossref","first-page":"924","DOI":"10.4254\/wjh.v8.i22.924","article-title":"Cholesterol metabolism in cholestatic liver disease and liver transplantation: from molecular mechanisms to clinical implications","volume":"8","author":"Nemes","year":"2016","journal-title":"WJH"},{"issue":"1-2","key":"10.1016\/j.jacl.2025.05.015_bib0025","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1007\/BF00441853","article-title":"Significance of serum lipoprotein-X and gammaglutamyltranspeptidase in the diagnosis of biliary atresia. A preliminary study in 27 cholestatic young infants","volume":"145","author":"Tazawa","year":"1986","journal-title":"Eur J Pediatr"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0026","doi-asserted-by":"crossref","first-page":"90","DOI":"10.4158\/EP11212.RA","article-title":"Severe hypercholesterolemia in patients with graft-vs-host disease affecting the liver after stem cell transplantation","volume":"18","author":"Joukhadar","year":"2012","journal-title":"Endocrine Pract"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0027","doi-asserted-by":"crossref","DOI":"10.7326\/aimcc.2023.0813","article-title":"Lipoprotein X in the setting of COVID-19\u2013Induced cholangiopathy: an unforeseen event","volume":"3","author":"Patel","year":"2024","journal-title":"AIM Clin Cases"},{"issue":"9","key":"10.1016\/j.jacl.2025.05.015_bib0028","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.3390\/biomedicines9091090","article-title":"The NIH lipo-COVID study: a pilot NMR investigation of lipoprotein subfractions and other metabolites in patients with severe COVID-19","volume":"9","author":"Ballout","year":"2021","journal-title":"Biomedicines"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0029","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.aace.2023.01.001","article-title":"Hypercholesterolemia after COVID-19: time to include lipoprotein X among the differential diagnoses","volume":"9","author":"Girard","year":"2023","journal-title":"AACE Clin Case Rep"},{"issue":"6","key":"10.1016\/j.jacl.2025.05.015_bib0030","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/0016-5085(85)90642-0","article-title":"Lipoprotein abnormalities in primary biliary cirrhosis. Association with hepatic lipase inhibition as well as altered cholesterol esterification","volume":"89","author":"Jahn","year":"1985","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0031","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1002\/hep.1840180117","article-title":"Decrease of hepatic triglyceride lipase levels and increase of cholesteryl ester transfer protein levels in patients with primary biliary cirrhosis: relationship to abnormalities in high-density lipoprotein","volume":"18","author":"Hiraoka","year":"1993","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.jacl.2025.05.015_bib0032","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1172\/JCI109633","article-title":"Appearance and characterization of lipoprotein X during continuous intralipid infusions in the neonate","volume":"64","author":"Griffin","year":"1979","journal-title":"J Clin Investig"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0033","first-page":"155","article-title":"Intravenous intralipid 10% versus. 20%, hyperlipidemia, and increase in lipoprotein X in humans","volume":"8","author":"Tashiro","year":"1992","journal-title":"Nutrition"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0034","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0014-5793(73)80511-3","article-title":"Isolation and characterization of lipoprotein-X (LP-X) from canine","volume":"38","author":"Muller","year":"1973","journal-title":"FEBS Lett"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0035","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0016-5085(78)90398-0","article-title":"Lipoprotein-X levels in extrahepatic versus intrahepatic cholestasis","volume":"75","author":"Simon","year":"1978","journal-title":"Gastroenterology"},{"issue":"8","key":"10.1016\/j.jacl.2025.05.015_bib0036","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/S0022-2275(20)38783-6","article-title":"Recognition of vesicular lipoproteins by the apolipoprotein B,E receptor of cultured fibroblasts","volume":"27","author":"Williams","year":"1986","journal-title":"J Lipid Res"},{"issue":"6","key":"10.1016\/j.jacl.2025.05.015_bib0037","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1042\/cs0560575","article-title":"Lecithin-cholesterol acyltransferase and the lipoprotein abnormalities of parenchymal liver disease","volume":"56","author":"Day","year":"1979","journal-title":"Clin Sci (Lond)"},{"issue":"5","key":"10.1016\/j.jacl.2025.05.015_bib0038","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1002\/hep.510280506","article-title":"Lipoprotein\u2013X in patients with cirrhosis: its relationship to cholestasis and hypercholesterolemia","volume":"28","author":"S\u00f6r\u00f6s","year":"1998","journal-title":"Hepatology"},{"issue":"11","key":"10.1016\/j.jacl.2025.05.015_bib0039","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1016\/S0022-2275(20)39715-7","article-title":"Role of lecithin:cholesterol acyltransferase and apolipoprotein A-I in cholesterol esterification in lipoprotein-X in vitro","volume":"36","author":"O","year":"1995","journal-title":"J Lipid Res"},{"issue":"10","key":"10.1016\/j.jacl.2025.05.015_bib0040","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1161\/CIRCULATIONAHA.118.035358","article-title":"Is low-density lipoprotein cholesterol the key to interpret the role of lecithin:cholesterol acyltransferase in atherosclerosis?","volume":"138","author":"Vitali","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.jacl.2025.05.015_bib0041","series-title":"The HDL Handbook","first-page":"159","article-title":"Chapter 7 - role of lecithin: cholesterol acyltransferase in HDL metabolism and atherosclerosis","author":"Ahsan","year":"2014"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0042","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1046\/j.1523-1755.2001.060002520.x","article-title":"Lipoprotein-X stimulates monocyte chemoattractant protein-1 expression in mesangial cells via nuclear factor-kappa B","volume":"60","author":"Lynn","year":"2001","journal-title":"Kidney Int"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0043","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0150083","article-title":"Lipoprotein X causes renal disease in LCAT deficiency","volume":"11","author":"Ossoli","year":"2016","journal-title":"PLOS ONE"},{"issue":"4","key":"10.1016\/j.jacl.2025.05.015_bib0044","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/S0002-9440(10)63386-X","article-title":"A novel in vivo lecithin-cholesterol acyltransferase (LCAT)-deficient mouse expressing predominantly LpX is associated with spontaneous glomerulopathy","volume":"165","author":"Zhu","year":"2004","journal-title":"Am J Pathol"},{"issue":"10","key":"10.1016\/j.jacl.2025.05.015_bib0045","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1161\/CIRCULATIONAHA.118.034706","article-title":"Complete and partial lecithin:cholesterol acyltransferase deficiency is differentially associated with atherosclerosis","volume":"138","author":"Oldoni","year":"2018","journal-title":"Circulation"},{"issue":"10","key":"10.1016\/j.jacl.2025.05.015_bib0046","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1161\/CIRCULATIONAHA.118.035358","article-title":"Is low-density lipoprotein cholesterol the key to interpret the role of lecithin:cholesterol acyltransferase in atherosclerosis?","volume":"138","author":"Vitali","year":"2018","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0047","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1097\/MED.0000000000000466","article-title":"Controversy over the atherogenicity of lipoprotein-X","volume":"26","author":"Miida","year":"2019","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0048","first-page":"283","article-title":"Detection of lipoprotein X (LpX): a challenge in patients with severe hypercholesterolaemia","volume":"39","author":"Cwiklinska","year":"2020","journal-title":"J med Biochem"},{"issue":"10","key":"10.1016\/j.jacl.2025.05.015_bib0049","first-page":"364","article-title":"Changes in the lipid profile in chronic hepatopathies","volume":"102","author":"Perales","year":"1994","journal-title":"Med Clin (Barc)"},{"issue":"5","key":"10.1016\/j.jacl.2025.05.015_bib0050","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1194\/jlr.D090233","article-title":"Plasma lipoprotein-X quantification on filipin-stained gels: monitoring recombinant LCAT treatment ex vivo","volume":"60","author":"Freeman","year":"2019","journal-title":"J Lipid Res"},{"issue":"20","key":"10.1016\/j.jacl.2025.05.015_bib0051","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1016\/j.jaccas.2022.09.001","article-title":"Lipoprotein-X and lipoprotein-Z induced hyperviscosity syndrome in the setting of cholestatic liver failure","volume":"4","author":"Waksman","year":"2022","journal-title":"JACC Case rep"},{"issue":"8, Part A","key":"10.1016\/j.jacl.2025.05.015_bib0052","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.bbalip.2016.04.016","article-title":"Lipid profiling of lipoprotein X: implications for dyslipidemia in cholestasis","volume":"1861","author":"Heimerl","year":"2016","journal-title":"Biochimica et Biophysica Acta (BBA) - Mol Cell Biol Lipids"},{"key":"10.1016\/j.jacl.2025.05.015_bib0053","doi-asserted-by":"crossref","DOI":"10.1177\/1179551419878687","article-title":"Hypercholesterolemia due to lipoprotein X: case report and thematic review","volume":"12","author":"Kattah","year":"2019","journal-title":"Clin Med Insights Endocrinol Diabetes"},{"issue":"4","key":"10.1016\/j.jacl.2025.05.015_bib0054","article-title":"Effect of lipoprotein-X on hepatic cholesterol synthesis","volume":"26","author":"M","year":"1977","journal-title":"Atherosclerosis"},{"issue":"4","key":"10.1016\/j.jacl.2025.05.015_bib0055","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/00041433-199908000-00002","article-title":"Hepatocellular transport and secretion of biliary lipids","volume":"10","author":"Cohen","year":"1999","journal-title":"Curr Opin Lipidol"},{"issue":"5","key":"10.1016\/j.jacl.2025.05.015_bib0056","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1172\/JCI108393","article-title":"Formation of lipoprotein-X. Its relationship to bile compounds","volume":"57","author":"Manzato","year":"1976","journal-title":"J Clin Invest"},{"issue":"9","key":"10.1016\/j.jacl.2025.05.015_bib0057","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1172\/JCI3597","article-title":"Class III P-glycoproteins mediate the formation of lipoprotein X in the mouse","volume":"102","author":"Elferink","year":"1998","journal-title":"J Clin Invest"},{"issue":"7","key":"10.1016\/j.jacl.2025.05.015_bib0058","doi-asserted-by":"crossref","first-page":"3459","DOI":"10.1073\/pnas.75.7.3459","article-title":"Secretion of lipoprotein-X by perfused livers of rats with cholestasis","volume":"75","author":"Felker","year":"1978","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"10","key":"10.1016\/j.jacl.2025.05.015_bib0059","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.1172\/JCI119799","article-title":"Hepatic secretion of phospholipid vesicles in the mouse critically depends on mdr2 or MDR3 P-glycoprotein expression. Visualization by electron microscopy","volume":"100","author":"Crawford","year":"1997","journal-title":"J Clin Invest"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0060","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.apsb.2015.01.002","article-title":"Emerging role of microRNAs in lipid metabolism","volume":"5","author":"Yang","year":"2015","journal-title":"Acta Pharm Sin B"},{"issue":"15","key":"10.1016\/j.jacl.2025.05.015_bib0061","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1161\/CIRCULATIONAHA.122.061578","article-title":"Very high cholesterol mimicking homozygous familial hypercholesterolemia","volume":"146","author":"Shotwell","year":"2022","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0062","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.metabol.2008.08.005","article-title":"Effects of bezafibrate on dyslipidemia with cholestasis in children with familial intrahepatic cholestasis\u20131 deficiency manifesting progressive familial intrahepatic cholestasis","volume":"58","author":"Nagasaka","year":"2009","journal-title":"Metabolism"},{"issue":"25","key":"10.1016\/j.jacl.2025.05.015_bib0063","doi-asserted-by":"crossref","first-page":"16237","DOI":"10.1073\/pnas.252582399","article-title":"Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion","volume":"99","author":"Yu","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"48","key":"10.1016\/j.jacl.2025.05.015_bib0064","doi-asserted-by":"crossref","first-page":"48275","DOI":"10.1074\/jbc.M310223200","article-title":"ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion","volume":"278","author":"Graf","year":"2003","journal-title":"J Biol Chem"},{"issue":"6","key":"10.1016\/j.jacl.2025.05.015_bib0065","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.jacl.2020.08.012","article-title":"Monocyte phenotyping and management of lipoprotein X syndrome","volume":"14","author":"Lian","year":"2020","journal-title":"J Clin Lipidol"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0066","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.jacl.2016.10.013","article-title":"Lipoprotein-X in cholestatic patients causes xanthomas and promotes foam cell formation in human macrophages","volume":"11","author":"Suzuki","year":"2017","journal-title":"J Clin Lipidol"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0067","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.jacl.2015.12.020","article-title":"Severe hypercholesterolemia and liver disease in a 3-year old","volume":"10","author":"Patel","year":"2016","journal-title":"J Clin Lipidol"},{"issue":"5 Pt 1","key":"10.1016\/j.jacl.2025.05.015_bib0068","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/0016-5085(90)90356-6","article-title":"Hyperviscosity syndrome in a hypercholesterolemic patient with primary biliary cirrhosis","volume":"98","author":"Rosenson","year":"1990","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0069","doi-asserted-by":"crossref","DOI":"10.1002\/jca.22105","article-title":"Use of therapeutic plasma exchange to remove lipoprotein X in a patient with vanishing bile duct syndrome presenting with cholestasis, pseudohyponatremia, and hypercholesterolemia: A case report and review of literature","volume":"39","author":"Jung","year":"2024","journal-title":"J Clin Apher"},{"key":"10.1016\/j.jacl.2025.05.015_bib0070","unstructured":"Ashorobi D, Liao H. Lipoprotein X-induced hyperlipidemia. In: StatPearls. StatPearls Publishing; 2025. Accessed February 23, 2025. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK572143\/"},{"issue":"6","key":"10.1016\/j.jacl.2025.05.015_bib0071","doi-asserted-by":"crossref","first-page":"924","DOI":"10.5604\/16652681.1171785","article-title":"Severe hypercholesterolemia mediated by lipoprotein X in a patient with cholestasis","volume":"14","author":"Phatlhane","year":"2015","journal-title":"Annals of Hepatology"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0072","first-page":"457","article-title":"Solitary pulmonary cholesteroloma, multiple xanthelasmas and lipemia retinalis complicating hypercholesterolemia after bone marrow transplantation","volume":"18","author":"Toren","year":"1996","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.jacl.2025.05.015_bib0073","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s12950-019-0211-5","article-title":"Accumulation of free cholesterol and oxidized low-density lipoprotein is associated with portal inflammation and fibrosis in nonalcoholic fatty liver disease","volume":"16","author":"Ho","year":"2019","journal-title":"J Inflamm (Lond)"},{"issue":"11","key":"10.1016\/j.jacl.2025.05.015_bib0074","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/S0022-2275(20)38428-5","article-title":"Large lipoproteins are excluded from the arterial wall in diabetic cholesterol-fed rabbits","volume":"29","author":"Nordestgaard","year":"1988","journal-title":"J Lipid Res"},{"issue":"11","key":"10.1016\/j.jacl.2025.05.015_bib0075","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1194\/jlr.M400229-JLR200","article-title":"Lipoprotein-X reduces LDL atherogenicity in primary biliary cirrhosis by preventing LDL oxidation","volume":"45","author":"Chang","year":"2004","journal-title":"J Lipid Res"},{"issue":"4","key":"10.1016\/j.jacl.2025.05.015_bib0076","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.jacl.2011.04.004","article-title":"Multiple lipoprotein and electrolyte laboratory artifacts caused by lipoprotein X in obstructive biliary cholestasis secondary to pancreatic cancer","volume":"5","author":"Sivakumar","year":"2011","journal-title":"J Clin Lipidol"},{"issue":"9","key":"10.1016\/j.jacl.2025.05.015_bib0077","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1093\/clinchem\/46.9.1351","article-title":"Evaluation of two different homogeneous assays for LDL-cholesterol in lipoprotein-X-positive serum","volume":"46","author":"Fei","year":"2000","journal-title":"Clin Chem"},{"key":"10.1016\/j.jacl.2025.05.015_bib0078","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.cca.2014.09.030","article-title":"Differences in reaction specificity toward lipoprotein X and abnormal LDL among 6 homogeneous assays for LDL-cholesterol","volume":"439","author":"Matsushima","year":"2015","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.jacl.2025.05.015_bib0079","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.clinbiochem.2021.04.017","article-title":"Clinical laboratory characteristics of patients with obstructive jaundice accompanied by dyslipidemia","volume":"94","author":"Zhao","year":"2021","journal-title":"Clin Biochem"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0080","first-page":"43","article-title":"Laboratory investigation of lipoprotein X","volume":"12","author":"GND","year":"2017","journal-title":"Clin Lipidol"},{"issue":"11","key":"10.1016\/j.jacl.2025.05.015_bib0081","first-page":"690","article-title":"When LDL cholesterol is not LDL cholesterol: LpX, A clinical lesson","volume":"4","author":"Huygen","year":"2022","journal-title":"JACC: Case Rep"},{"issue":"6","key":"10.1016\/j.jacl.2025.05.015_bib0082","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.amjcard.2012.04.062","article-title":"Secondary causes of dyslipidemia","volume":"110","author":"Vodnala","year":"2012","journal-title":"Am J Cardiol"},{"issue":"24","key":"10.1016\/j.jacl.2025.05.015_bib0083","doi-asserted-by":"crossref","first-page":"3168","DOI":"10.1016\/j.jacc.2018.11.002","article-title":"2018 AHA\/ACC\/AACVPR\/AAPA\/ABC\/ACPM\/ADA\/AGS\/APhA\/ASPC\/NLA\/PCNA Guideline on the management of blood Cholesterol: Executive summary: A report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice guidelines","volume":"73","author":"Grundy","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacl.2025.05.015_bib0084","series-title":"Therapeutic Lipidology","first-page":"35","article-title":"Genetic disorders of lipoprotein metabolism","author":"Brown","year":"2021"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0085","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0009-8981(83)90165-1","article-title":"A novel assay for the quantitative determination of lipoprotein-X (LP-X) in serum","volume":"127","author":"Bos","year":"1983","journal-title":"Clinica Chimica Acta"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0086","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/0009-8981(74)90010-2","article-title":"A method for quantitative determination of the abnormal lipoprotein of cholestasis, LP-X","volume":"55","author":"Ritland","year":"1974","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.jacl.2025.05.015_bib0087","doi-asserted-by":"crossref","DOI":"10.3389\/fnume.2022.960522","article-title":"Clinical relevance of nuclear magnetic resonance LipoProfile","volume":"2","author":"Emeasoba","year":"2022","journal-title":"Front Nucl Med"},{"issue":"5","key":"10.1016\/j.jacl.2025.05.015_bib0088","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1194\/jlr.D090233","article-title":"Plasma lipoprotein-X quantification on filipin-stained gels: monitoring recombinant LCAT treatment ex vivo","volume":"60","author":"Freeman","year":"2019","journal-title":"Journal of lipid research"},{"key":"10.1016\/j.jacl.2025.05.015_bib0089","unstructured":"Rao N, Jain A, Goyale A, Persaud J, Al-Musalhi K, Nair DR. Lipoprotein X in autoimmune liver disease causing interference in routine and specialist biochemical investigations. Clin Lipidol. Published online 2017. Accessed March 1, 2025. https:\/\/www.semanticscholar.org\/paper\/Lipoprotein-X-in-autoimmune-liver-disease-causing-Rao-Jain\/a437270c461f4b5e30b686fce64a270f8dccbc1a"},{"issue":"10","key":"10.1016\/j.jacl.2025.05.015_bib0090","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1194\/jlr.R900015-JLR200","article-title":"Lipoproteomics: using mass spectrometry-based proteomics to explore the assembly, structure, and function of lipoproteins: thematic review series: proteomics","volume":"50","author":"Hoofnagle","year":"2009","journal-title":"J Lipid Res"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0091","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0009-8981(79)90437-6","article-title":"Turbidimetric determination of lipoprotein-X in serum","volume":"96","author":"Talafant","year":"1979","journal-title":"Clin Chim Acta"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0092","first-page":"155","article-title":"Enzymatic determination of lipoprotein-X, a specific serum cholestasis marker","volume":"19","author":"Talafant","year":"1981","journal-title":"J Clin Chem Clin Biochem"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0093","first-page":"163","article-title":"Dye-binding method for rapid colorimetric determination of the cholestasis characterizing lipoprotein-X","volume":"20","author":"Talafant","year":"1982","journal-title":"J Clin Chem Clin Biochem"},{"issue":"8","key":"10.1016\/j.jacl.2025.05.015_bib0094","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.3390\/biology11081248","article-title":"A simple fluorescent cholesterol labeling method to cryoprotect and detect plasma lipoprotein-X","volume":"11","author":"Neufeld","year":"2022","journal-title":"Biology"},{"issue":"4 Pt 1","key":"10.1016\/j.jacl.2025.05.015_bib0095","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1093\/clinchem\/28.4.606","article-title":"Simple, direct measurement of lipoprotein X in serum","volume":"28","author":"Hashiguchi","year":"1982","journal-title":"Clin Chem"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0096","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.jacl.2014.11.007","article-title":"Extreme hypercholesterolemia presenting with pseudohyponatremia - a case report and review of the literature","volume":"9","author":"Hussain","year":"2015","journal-title":"J Clin Lipidol"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0097","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1002\/jcla.1860080311","article-title":"Clinical significance of serum high-molecular-mass alkaline phosphatase, alkaline phosphatase-lipoprotein-X complex, and intestinal variant alkaline phosphatase","volume":"8","author":"Wolf","year":"1994","journal-title":"J Clin Lab Anal"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0098","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0009-8981(76)90335-1","article-title":"Serum alkaline phosphatase, nucleotide pyrophosphatase, 5\u2019-nucleotide and lipoprotein-X in cholestasis","volume":"67","author":"Brocklehurst","year":"1976","journal-title":"Clin Chim Acta"},{"issue":"6","key":"10.1016\/j.jacl.2025.05.015_bib0099","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1093\/clinchem\/27.6.867","article-title":"High-molecular-mass alkaline phosphatase in serum and bile: nature and relationship with lipoprotein-X","volume":"27","author":"Crofton","year":"1981","journal-title":"Clin Chem"},{"issue":"9","key":"10.1016\/j.jacl.2025.05.015_bib0100","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.3390\/jcm9092915","article-title":"Characterization of LP-Z lipoprotein particles and quantification in subjects with liver disease using a newly developed NMR-based assay","volume":"9","author":"Bedi","year":"2020","journal-title":"J Clin Med"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0101","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/ajg.2017.287","article-title":"Effects of bezafibrate on outcome and pruritus in primary biliary cholangitis with suboptimal ursodeoxycholic acid response","volume":"113","author":"Reig","year":"2018","journal-title":"Am J Gastroenterol"},{"issue":"4","key":"10.1016\/j.jacl.2025.05.015_bib0102","doi-asserted-by":"crossref","first-page":"305","DOI":"10.2217\/clp.15.23","article-title":"Management of lipoprotein X and its complications in a patient with primary sclerosing cholangitis","volume":"10","author":"Brandt","year":"2015","journal-title":"Clin Lipidol"},{"key":"10.1016\/j.jacl.2025.05.015_bib0103","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2022.969081","article-title":"Case report: unusual and extremely severe lipoprotein X-mediated hypercholesterolemia in extrahepatic pediatric cholestasis","volume":"10","author":"Colantuono","year":"2022","journal-title":"Front Pediatr"},{"issue":"5","key":"10.1016\/j.jacl.2025.05.015_bib0104","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1159\/000526854","article-title":"Severe hypercholesterolemia mediated by lipoprotein X in an immunosuppressed patient: A case report","volume":"30","author":"Sequeira","year":"2023","journal-title":"GE Port J Gastroenterol"},{"key":"10.1016\/j.jacl.2025.05.015_bib0105","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.metabol.2017.04.004","article-title":"High prevalence of apolipoprotein B dyslipoproteinemias in non-alcoholic fatty liver disease: the lifelines cohort study","volume":"72","author":"Nass","year":"2017","journal-title":"Metabolism"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0106","article-title":"The correlation between blood lipids and intrahepatic cholestasis syndrome during pregnancy","volume":"44","author":"Huang","year":"2024","journal-title":"J Obstetr Gynaecol"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0107","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1038\/s41598-017-00944-9","article-title":"Serum metabolomics analysis reveals a distinct metabolic profile of patients with primary biliary cholangitis","volume":"7","author":"Hao","year":"2017","journal-title":"Sci Rep"},{"issue":"6","key":"10.1016\/j.jacl.2025.05.015_bib0108","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1161\/01.ATV.0000217910.90210.99","article-title":"Human lecithin:cholesterol acyltransferase deficiency: in vivo kinetics of low-density lipoprotein and lipoprotein-X","volume":"26","author":"Nishiwaki","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"5","key":"10.1016\/j.jacl.2025.05.015_bib0109","doi-asserted-by":"crossref","first-page":"3511","DOI":"10.1074\/jbc.M109883200","article-title":"Lecithin:cholesterol acyltransferase deficiency increases atherosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice*","volume":"277","author":"Furbee","year":"2002","journal-title":"J Biol Chem"},{"issue":"5","key":"10.1016\/j.jacl.2025.05.015_bib0110","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1002\/hep.1840150518","article-title":"Hypercholesterolemia and atherosclerosis in primary biliary cirrhosis: what is the risk?","volume":"15","author":"Crippin","year":"1992","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0111","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1161\/CIRCOUTCOMES.110.959247","article-title":"A meta-analysis of low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B as markers of cardiovascular risk","volume":"4","author":"Sniderman","year":"2011","journal-title":"Circ Cardiovasc Qual Outcomes"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0112","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.atherosclerosis.2009.08.052","article-title":"Low-dose atorvastatin improves dyslipidemia and vascular function in patients with primary biliary cirrhosis after one year of treatment","volume":"209","author":"Stojakovic","year":"2010","journal-title":"Atherosclerosis"},{"issue":"8","key":"10.1016\/j.jacl.2025.05.015_bib0113","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1111\/liv.12191","article-title":"Randomized controlled trial assessing the effect of simvastatin in primary biliary cirrhosis","volume":"33","author":"Cash","year":"2013","journal-title":"Liver Int"},{"issue":"4","key":"10.1016\/j.jacl.2025.05.015_bib0114","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/S0168-8278(02)00006-5","article-title":"Simvastatin in primary biliary cirrhosis: effects on serum lipids and distinct disease markers","volume":"36","author":"Ritzel","year":"2002","journal-title":"J Hepatol"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0115","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.atherosclerosis.2006.11.036","article-title":"Primary biliary cirrhosis, hyperlipidemia, and atherosclerotic risk: a systematic review","volume":"194","author":"Sorokin","year":"2007","journal-title":"Atherosclerosis"},{"issue":"15","key":"10.1016\/j.jacl.2025.05.015_bib0116","doi-asserted-by":"crossref","first-page":"28J","DOI":"10.1016\/0002-9149(88)90004-5","article-title":"Efficacy and long-term adverse effect pattern of lovastatin","volume":"62","author":"Tobert","year":"1988","journal-title":"Am J Cardiol"},{"issue":"1","key":"10.1016\/j.jacl.2025.05.015_bib0117","first-page":"89","article-title":"Metabolism of cholesterol and low- and high-density lipoproteins in primary biliary cirrhosis: cholesterol absorption and synthesis related to lipoprotein levels and their kinetics","volume":"21","author":"Gylling","year":"1995","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0118","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1053\/j.gastro.2005.06.019","article-title":"Efficacy and safety of ursodeoxycholic acid versus cholestyramine in intrahepatic cholestasis of pregnancy","volume":"129","author":"Kondrackiene","year":"2005","journal-title":"Gastroenterology"},{"issue":"4","key":"10.1016\/j.jacl.2025.05.015_bib0119","doi-asserted-by":"crossref","first-page":"307","DOI":"10.3109\/00016347509156759","article-title":"Studies in cholestasis of pregnancy. IV. Serum lipids and lipoproteins in relation to duration of symptoms and severity of the disease, and fatty acid composition of lecithin in relation to duration of symptoms","volume":"54","author":"Johnson","year":"1975","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"6","key":"10.1016\/j.jacl.2025.05.015_bib0120","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/j.1365-2362.1978.tb00871.x","article-title":"Quantitative changes of serum lipoprotein-X after cholestyramine administration in infants with cholestatic biliary tract and liver disease","volume":"8","author":"Poley","year":"1978","journal-title":"Eur J Clin Investig"},{"key":"10.1016\/j.jacl.2025.05.015_bib0121","article-title":"Lipoprotein-X accumulation: a mimic of familial hypercholesterolemia","year":"2013","journal-title":"Consultant360"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0122","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0021-9150(94)05521-J","article-title":"Lipoprotein pattern and plasma lecithin cholesterol acyl transferase activity in children with Alagille syndrome","volume":"115","author":"Gottrand","year":"1995","journal-title":"Atherosclerosis"},{"issue":"7","key":"10.1016\/j.jacl.2025.05.015_bib0123","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s11883-023-01113-2","article-title":"Lipoprotein apheresis: current recommendations for treating familial hypercholesterolemia and elevated Lipoprotein(a)","volume":"25","author":"Safarova","year":"2023","journal-title":"Curr Atheroscler Rep"},{"issue":"5-6","key":"10.1016\/j.jacl.2025.05.015_bib0124","first-page":"160","article-title":"Plasmapheresis efficacy in the treatment of patients with chronic cholestatic hepatitis and primary biliary liver cirrhosis]","author":"Radchenko","year":"1995","journal-title":"Lik Sprava"},{"issue":"9","key":"10.1016\/j.jacl.2025.05.015_bib0125","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1111\/j.1525-1594.1995.tb02455.x","article-title":"Different apheresis methods in the treatment of hypercholesterolemia in primary biliary cirrhosis: a case report","volume":"19","author":"Kojima","year":"1995","journal-title":"Artif Organs"},{"issue":"2","key":"10.1016\/j.jacl.2025.05.015_bib0126","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.jacl.2018.03.040","article-title":"Lipoprotein X in graft versus host disease of the liver*","volume":"12","author":"Gopal","year":"2018","journal-title":"J Clin Lipidol"},{"issue":"7","key":"10.1016\/j.jacl.2025.05.015_bib0127","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1161\/ATVBAHA.120.315719","article-title":"Correction of familial LCAT deficiency by AAV-hLCAT prevents renal injury and atherosclerosis in hamsters\u2014brief report","volume":"41","author":"Guo","year":"2021","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"3","key":"10.1016\/j.jacl.2025.05.015_bib0128","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/joim.13404","article-title":"The HDL mimetic CER-001 remodels plasma lipoproteins and reduces kidney lipid deposits in inherited lecithin:cholesterol acyltransferase deficiency","volume":"291","author":"Pavanello","year":"2021","journal-title":"J Int Med"}],"container-title":["Journal of Clinical Lipidology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933287425003058?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933287425003058?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T15:47:59Z","timestamp":1750693679000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1933287425003058"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":128,"alternative-id":["S1933287425003058"],"URL":"https:\/\/doi.org\/10.1016\/j.jacl.2025.05.015","relation":{},"ISSN":["1933-2874"],"issn-type":[{"value":"1933-2874","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lipoprotein X \u2013 Pathophysiology, diagnosis, and management","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Lipidology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacl.2025.05.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 National Lipid Association. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}