{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T05:27:16Z","timestamp":1783574836089,"version":"3.55.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100017689","name":"Guangdong Provincial People's Hospital","doi-asserted-by":"publisher","award":["BY01202266"],"award-info":[{"award-number":["BY01202266"]}],"id":[{"id":"10.13039\/501100017689","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["8217020803"],"award-info":[{"award-number":["8217020803"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","award":["ESR-23-22118"],"award-info":[{"award-number":["ESR-23-22118"]}],"id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","lipidjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Lipidology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.jacl.2026.03.015","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T03:59:41Z","timestamp":1774583981000},"page":"1065-1077","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["HDL anti-inflammatory capacity and residual cardiovascular risk: A prospective cohort study"],"prefix":"10.1016","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6143-7044","authenticated-orcid":false,"given":"Congzhuo","family":"Jia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanying","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiayan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2224-4885","authenticated-orcid":false,"given":"Yong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacl.2026.03.015_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/S0735-1097(24)04310-9","article-title":"Global prevalence of coronary artery disease: an update from the global burden of disease study","volume":"83","author":"Stark","year":"2024","journal-title":"JACC"},{"key":"10.1016\/j.jacl.2026.03.015_bib2","doi-asserted-by":"crossref","first-page":"4184","DOI":"10.1093\/eurheartj\/ehae558","article-title":"Variation in secondary prevention of coronary heart disease: the INTERASPIRE study","volume":"45","author":"McEvoy","year":"2024","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacl.2026.03.015_bib3","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.ijcard.2014.04.227","article-title":"Is HDL a prognostic biomarker for coronary atherosclerosis?","volume":"174","author":"Papageorgiou","year":"2014","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jacl.2026.03.015_bib4","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1056\/NEJMoa1706444","article-title":"Effects of anacetrapib in patients with atherosclerotic vascular disease","volume":"377","author":"Bowman","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacl.2026.03.015_bib5","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1093\/eurheartj\/eht571","article-title":"Mendelian randomization of blood lipids for coronary heart disease","volume":"36","author":"Holmes","year":"2015","journal-title":"Eur Heart J."},{"key":"10.1016\/j.jacl.2026.03.015_bib6","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1161\/CIRCULATIONAHA.111.066589","article-title":"Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport","volume":"125","author":"Rosenson","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.jacl.2026.03.015_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2024.108684","article-title":"HDL-based therapeutics: a promising frontier in combating viral and bacterial infections","volume":"260","author":"Rani","year":"2024","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.jacl.2026.03.015_bib8","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1093\/eurheartj\/ehx665","article-title":"U-shaped relationship of HDL and risk of infectious disease: two prospective population-based cohort studies","volume":"39","author":"Madsen","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacl.2026.03.015_bib9","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1161\/01.ATV.15.11.1987","article-title":"High-density lipoproteins inhibit cytokine-induced expression of endothelial cell adhesion molecules","volume":"15","author":"Cockerill","year":"1995","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jacl.2026.03.015_bib10","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/bph.12174","article-title":"HDL and endothelial protection","volume":"169","author":"Tran-Dinh","year":"2013","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.jacl.2026.03.015_bib11","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1161\/CIRCRESAHA.111.300104","article-title":"High-density lipoproteins inhibit vascular endothelial inflammation by increasing 3\u03b2-hydroxysteroid-\u039424 reductase expression and inducing heme oxygenase-1","volume":"112","author":"Wu","year":"2013","journal-title":"Circ Res"},{"key":"10.1016\/j.jacl.2026.03.015_bib12","doi-asserted-by":"crossref","first-page":"946","DOI":"10.2337\/dc18-1510","article-title":"Body composition and diabetes risk in South Asians: findings from the MASALA and MESA studies","volume":"42","author":"Flowers","year":"2019","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jacl.2026.03.015_bib13","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1161\/CIRCULATIONAHA.113.005757","article-title":"Racial\/ethnic differences in dyslipidemia patterns","volume":"129","author":"Frank","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.jacl.2026.03.015_bib14","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1093\/eurheartj\/ehad191","article-title":"2023 ESC Guidelines for the management of acute coronary syndromes","volume":"44","author":"Byrne","year":"2023","journal-title":"Eur Heart J"},{"issue":"suppl 1","key":"10.1016\/j.jacl.2026.03.015_bib15","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.2337\/dc25-S002","article-title":"2. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes-2025","volume":"48","author":"American Diabetes Association Professional Practice Committee","year":"2025","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jacl.2026.03.015_bib16","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jacl.2026.03.015_bib17","series-title":"Regression Modeling Strategies: With Applications to Linear Models, Logistic Regression, and Survival Analysis","author":"Harrell","year":"2001"},{"key":"10.1016\/j.jacl.2026.03.015_bib18","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1037\/a0031034","article-title":"Mediation analysis allowing for exposure-mediator interactions and causal interpretation: theoretical assumptions and implementation with SAS and SPSS macros","volume":"18","author":"Valeri","year":"2013","journal-title":"Psychol Methods"},{"key":"10.1016\/j.jacl.2026.03.015_bib19","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1177\/0271678X231184806","article-title":"HDL anti-inflammatory function is impaired and associated with high SAA1 and low APOA4 levels in aneurysmal subarachnoid hemorrhage","volume":"43","author":"Az\u00faa-l\u00f3pez","year":"2023","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.jacl.2026.03.015_bib20","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1093\/cvr\/cvs089","article-title":"High-density lipoprotein loses its anti-inflammatory capacity by accumulation of pro-inflammatory-serum amyloid A","volume":"94","author":"T\u00d6lle","year":"2012","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jacl.2026.03.015_bib21","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1067\/mhj.2001.109946","article-title":"Effect of menopause on plaque morphologic characteristics in coronary atherosclerosis","volume":"141","author":"Burke","year":"2001","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacl.2026.03.015_bib22","first-page":"604","article-title":"Sex- and age-related differences in outcomes of patients with acute myocardial infarction: MINOCA vs. MIOCA","volume":"12","author":"Canton","year":"2023","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"10.1016\/j.jacl.2026.03.015_bib23","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1161\/CIRCULATIONAHA.116.023266","article-title":"Excess cardiovascular risk in women relative to men referred for coronary angiography is associated with severely impaired coronary flow reserve, not obstructive disease","volume":"135","author":"Taqueti","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.jacl.2026.03.015_bib24","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.cca.2014.02.026","article-title":"The HDL anti-inflammatory function is impaired in myocardial infarction and may predict new cardiac events independent of HDL cholesterol","volume":"433","author":"Dullaart","year":"2014","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.jacl.2026.03.015_bib25","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1161\/01.RES.0000225982.01988.93","article-title":"Endothelial and antithrombotic actions of HDL","volume":"98","author":"Mineo","year":"2006","journal-title":"Circ Res"},{"key":"10.1016\/j.jacl.2026.03.015_bib26","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/nrcardio.2015.124","article-title":"Dysfunctional HDL and atherosclerotic cardiovascular disease","volume":"13","author":"Rosenson","year":"2016","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.jacl.2026.03.015_bib27","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.3390\/jcm9072269","article-title":"Changes in high-density lipoproteins related to outcomes in patients with acute stroke","volume":"9","author":"Varela","year":"2020","journal-title":"J Clin Med"},{"key":"10.1016\/j.jacl.2026.03.015_bib28","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1007\/s10741-025-10519-w","article-title":"A comprehensive review: unraveling the role of inflammation in the etiology of heart failure","volume":"30","author":"Roman-Pepine","year":"2025","journal-title":"Heart Fail Rev"},{"key":"10.1016\/j.jacl.2026.03.015_bib29","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1016\/j.amjcard.2013.07.045","article-title":"Heart failure is associated with impaired anti-inflammatory and antioxidant properties of high-density lipoproteins","volume":"112","author":"Kim","year":"2013","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacl.2026.03.015_bib30","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.120.019123","article-title":"Impaired high-density lipoprotein function in patients with heart failure","volume":"10","author":"Emmens","year":"2021","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.jacl.2026.03.015_bib31","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1007\/s10741-020-09916-0","article-title":"High-density lipoprotein-mediated cardioprotection in heart failure","volume":"26","author":"Jackson","year":"2021","journal-title":"Heart Fail Rev"},{"key":"10.1016\/j.jacl.2026.03.015_bib32","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/labinvest.2016.56","article-title":"ApoA1 and ApoA1-specific self-antibodies in cardiovascular disease","volume":"96","author":"Chistiakov","year":"2016","journal-title":"Lab Invest"},{"key":"10.1016\/j.jacl.2026.03.015_bib33","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1056\/NEJM200003233421202","article-title":"C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women","volume":"342","author":"Ridker","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacl.2026.03.015_bib34","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s40164-024-00527-1","article-title":"The double-edged effects of IL-6 in liver regeneration, aging, inflammation, and diseases","volume":"13","author":"Wang","year":"2024","journal-title":"Exp Hematol Oncol"},{"key":"10.1016\/j.jacl.2026.03.015_bib35","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.3390\/cells10051061","article-title":"HDL in immune-inflammatory responses: implications beyond cardiovascular diseases","volume":"10","author":"Bonacina","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.jacl.2026.03.015_bib36","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1161\/CIRCRESAHA.123.321563","article-title":"HDL function and atherosclerosis: reactive dicarbonyls as promising targets of therapy","volume":"132","author":"Linton","year":"2023","journal-title":"Circ Res"},{"key":"10.1016\/j.jacl.2026.03.015_bib37","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/s41392-022-01036-5","article-title":"Signaling pathways of chronic kidney diseases, implications for therapeutics","volume":"7","author":"Yuan","year":"2022","journal-title":"Signal Transduct Target Ther"},{"key":"10.1016\/j.jacl.2026.03.015_bib38","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1124\/pr.58.3.1","article-title":"Functionally defective high-density lipoprotein: a new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosis","volume":"58","author":"Kontush","year":"2006","journal-title":"Pharmacol Rev"}],"container-title":["Journal of Clinical Lipidology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933287426000851?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933287426000851?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T23:37:23Z","timestamp":1781221043000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1933287426000851"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S1933287426000851"],"URL":"https:\/\/doi.org\/10.1016\/j.jacl.2026.03.015","relation":{},"ISSN":["1933-2874"],"issn-type":[{"value":"1933-2874","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"HDL anti-inflammatory capacity and residual cardiovascular risk: A prospective cohort study","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Lipidology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacl.2026.03.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Inc. on behalf of National Lipid Association.","name":"copyright","label":"Copyright"}]}}