{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T21:33:46Z","timestamp":1785188026728,"version":"3.55.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","lipidjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Lipidology"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.jacl.2026.03.022","type":"journal-article","created":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T03:23:06Z","timestamp":1775100186000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Lipoprotein(a) is associated with mitral annular calcification but not mitral regurgitation: A propensity-matched study of 66,292 pairs"],"prefix":"10.1016","author":[{"given":"Daoud","family":"Eldawud","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2095-8134","authenticated-orcid":false,"given":"Md","family":"Fahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keston","family":"Rattan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Alwahadneh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Khouri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1921-2199","authenticated-orcid":false,"given":"Louis","family":"Salciccioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jacl.2026.03.022_bib1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s40119-020-00177-4","article-title":"Lipoprotein(a) and cardiovascular disease prevention across diverse populations","volume":"9","author":"Pearson","year":"2020","journal-title":"Cardiol Ther"},{"issue":"1","key":"10.1016\/j.jacl.2026.03.022_bib2","doi-asserted-by":"crossref","first-page":"e48","DOI":"10.1161\/ATV.0000000000000147","article-title":"Lipoprotein(a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart Association","volume":"42","author":"Reyes-Soffer","year":"2022","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"7","key":"10.1016\/j.jacl.2026.03.022_bib3","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1194\/jlr.R051904","article-title":"Lipoprotein (a): impact by ethnicity and environmental and medical conditions","volume":"57","author":"Enkhmaa","year":"2016","journal-title":"J Lipid Res"},{"issue":"7","key":"10.1016\/j.jacl.2026.03.022_bib4","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.jacc.2021.11.055","article-title":"Repeat measures of lipoprotein(a) molar concentration and cardiovascular risk","volume":"79","author":"Trinder","year":"2022","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"10.1016\/j.jacl.2026.03.022_bib5","first-page":"748","article-title":"Prevalence of lipoprotein(a) measurement in patients with or at risk of cardiovascular disease","volume":"17","author":"Panza","year":"2023","journal-title":"J\u00a0Clin\u00a0Lipidol"},{"key":"10.1016\/j.jacl.2026.03.022_bib6","article-title":"An update on Lipoprotein (a): the latest on testing. treatment, and guideline recommendations: American College of Cardiology","author":"Alebna","year":"2023","journal-title":"Expert Anal"},{"issue":"17","key":"10.1016\/j.jacl.2026.03.022_bib7","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1016\/j.jacc.2015.08.872","article-title":"Mitral annulus calcification","volume":"66","author":"Abramowitz","year":"2015","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"10.1016\/j.jacl.2026.03.022_bib8","doi-asserted-by":"crossref","DOI":"10.1093\/jamiaopen\/ooad035","article-title":"A global federated real-world data and analytics platform for research","volume":"6","author":"Palchuk","year":"2023","journal-title":"JAMIA Open"},{"issue":"1","key":"10.1016\/j.jacl.2026.03.022_bib9","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s12170-025-00765-w","article-title":"Clinical update on the intersection of lipoprotein(a) and calcific valve disease","volume":"19","author":"Ashley","year":"2025","journal-title":"Curr Cardiovasc\u00a0Risk Rep"},{"key":"10.1016\/j.jacl.2026.03.022_bib10","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.atherosclerosis.2021.11.029","article-title":"Elevated lipoprotein(a) in mitral and aortic valve calcification and disease: the Copenhagen General Population Study","volume":"349","author":"Kaltoft","year":"2022","journal-title":"Atherosclerosis"},{"issue":"11","key":"10.1016\/j.jacl.2026.03.022_bib11","article-title":"Lipoprotein(a) and subclinical vascular and valvular calcification on cardiac computed tomography: the atherosclerosis risk in communities study","volume":"11","author":"Obisesan","year":"2022","journal-title":"J\u00a0Am\u00a0Heart Assoc"},{"issue":"2","key":"10.1016\/j.jacl.2026.03.022_bib12","first-page":"154","article-title":"Lipoprotein (a) and risk for calcification of the coronary arteries, mitral valve, and thoracic aorta: the Multi-Ethnic Study of Atherosclerosis","volume":"15","author":"Garg","year":"2021","journal-title":"J\u00a0Cardiovasc\u00a0Comput\u00a0Tomogr"},{"issue":"11_suppl","key":"10.1016\/j.jacl.2026.03.022_bib13","article-title":"The relationship between lipoprotein(a), mitral annular calcification, and mitral stenosis in a large cohort of dyslipidemia patients","volume":"71","author":"Shah","year":"2018","journal-title":"J\u00a0Am\u00a0Coll\u00a0Cardiol"},{"issue":"22","key":"10.1016\/j.jacl.2026.03.022_bib14","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1136\/heartjnl-2016-309404","article-title":"Association of inflammatory, lipid and mineral markers with cardiac calcification in older adults","volume":"102","author":"Bortnick","year":"2016","journal-title":"Heart"},{"issue":"1","key":"10.1016\/j.jacl.2026.03.022_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0021-9150(00)00737-1","article-title":"Mitral annulus calcification\u2014a window to diffuse atherosclerosis of the vascular system","volume":"155","author":"Adler","year":"2001","journal-title":"Atherosclerosis"},{"issue":"1","key":"10.1016\/j.jacl.2026.03.022_bib16","article-title":"Differences in risk factors associated with the initiation and progression of mitral annular calcification in asymptomatic individuals","volume":"15","author":"Kim","year":"2025","journal-title":"Sci Rep"},{"key":"10.1016\/j.jacl.2026.03.022_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijcard.2024.132741","article-title":"Atherosclerosis, calcific aortic valve disease and mitral annular calcification: same or different?","volume":"420","author":"Hafiane","year":"2025","journal-title":"Int J Cardiol"},{"issue":"5","key":"10.1016\/j.jacl.2026.03.022_bib18","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.numecd.2023.01.025","article-title":"High lipoprotein(a) levels and mitral valve disease: a systematic review","volume":"33","author":"Masson","year":"2023","journal-title":"Nutr Metab Cardiovasc Dis"},{"issue":"17","key":"10.1016\/j.jacl.2026.03.022_bib19","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1016\/j.jacc.2019.01.070","article-title":"Lipoprotein(a) and oxidized phospholipids promote valve calcification in patients with aortic stenosis","volume":"73","author":"Zheng","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.jacl.2026.03.022_bib20","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.amjcard.2009.09.042","article-title":"Mitral annular calcium causing mitral stenosis","volume":"105","author":"Pressman","year":"2010","journal-title":"Am J Cardiol"},{"issue":"9","key":"10.1016\/j.jacl.2026.03.022_bib21","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.echo.2021.04.007","article-title":"Mitral annular calcification and calcific mitral stenosis: role of echocardiography in hemodynamic assessment and management","volume":"34","author":"Silbiger","year":"2021","journal-title":"J Am Soc Echocardiogr"},{"issue":"6","key":"10.1016\/j.jacl.2026.03.022_bib22","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1161\/01.CIR.0000025426.39426.83","article-title":"Effect of annular shape on leaflet curvature in reducing mitral leaflet stress","volume":"106","author":"Salgo","year":"2002","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.jacl.2026.03.022_bib23","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1016\/j.jtcvs.2007.08.037","article-title":"A saddle-shaped annulus reduces systolic strain on the central region of the mitral valve anterior leaflet","volume":"134","author":"Jimenez","year":"2007","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"7","key":"10.1016\/j.jacl.2026.03.022_bib24","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.jacc.2022.05.032","article-title":"Mitral valve dysfunction in patients with annular calcification: JACC review topic of the week","volume":"80","author":"Churchill","year":"2022","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.jacl.2026.03.022_bib25","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.echo.2017.01.007","article-title":"Recommendations for noninvasive evaluation of native valvular regurgitation: a report from the American Society of Echocardiography developed in collaboration with the Society for Cardiovascular Magnetic Resonance","volume":"30","author":"Zoghbi","year":"2017","journal-title":"J Am Soc Echocardiogr"},{"issue":"2","key":"10.1016\/j.jacl.2026.03.022_bib26","doi-asserted-by":"crossref","first-page":"e183","DOI":"10.1016\/j.jtcvs.2021.04.002","article-title":"2020 ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"162","author":"Otto","year":"2021","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"7","key":"10.1016\/j.jacl.2026.03.022_bib27","first-page":"722","article-title":"Management of patients with severe mitral annular calcification: JACC state-of-the-art review","volume":"80","author":"Chehab","year":"2022","journal-title":"J\u00a0Am\u00a0Coll\u00a0Cardiol"},{"key":"10.1016\/j.jacl.2026.03.022_bib28","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s40265-025-02274-x","article-title":"Effect of proprotein convertase subtilisin\/kexin type 9 (PCSK9) inhibitors on lipoprotein(a) levels: an umbrella review of meta-analyses of randomized controlled trials","volume":"86","author":"Qiao","year":"2026","journal-title":"Drugs"}],"container-title":["Journal of Clinical Lipidology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933287426000929?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933287426000929?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T19:51:53Z","timestamp":1777060313000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1933287426000929"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":28,"alternative-id":["S1933287426000929"],"URL":"https:\/\/doi.org\/10.1016\/j.jacl.2026.03.022","relation":{},"ISSN":["1933-2874"],"issn-type":[{"value":"1933-2874","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lipoprotein(a) is associated with mitral annular calcification but not mitral regurgitation: A propensity-matched study of 66,292 pairs","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical Lipidology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacl.2026.03.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 National Lipid Association. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}