{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:53:01Z","timestamp":1791499981345,"version":"4.3.4"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacr.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Radiology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.jacr.2026.09.013","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T15:59:16Z","timestamp":1790006356000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Opportunistic Screening for Cardiovascular and Chronic Obstructive Pulmonary Disease Biomarkers and Implications for Downstream Care: A Retrospective Lung Cancer Screening Cohort Study"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6017-3470","authenticated-orcid":false,"given":"Lauren K.","family":"Groner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Patricia","family":"Puello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chukwuma","family":"Onyebeke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlene","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina Marulanda","family":"Corzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tashina","family":"Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Haile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Saleh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica M.","family":"Pena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4845-404X","authenticated-orcid":false,"given":"Daniel B.","family":"Green","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura C.","family":"Pinheiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacr.2026.09.013_bib1","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCOUTCOMES.121.007917","article-title":"Race, racism, and cardiovascular health: applying a social determinants of health framework to racial\/ethnic disparities in cardiovascular disease","volume":"15","author":"Javed","year":"2022","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"10.1016\/j.jacr.2026.09.013_bib2","doi-asserted-by":"crossref","DOI":"10.5888\/pcd21.240264","article-title":"Racial and ethnic disparities in perceived health status among patients with cardiovascular disease","volume":"21","author":"Zakeri M","year":"2024","journal-title":"Prev Chronic Dis"},{"key":"10.1016\/j.jacr.2026.09.013_bib3","article-title":"Racial and socioeconomic determinants of cardiovascular health: a comprehensive review","volume":"16","author":"Borkowski","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.jacr.2026.09.013_bib4","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1136\/jech.2009.089722","article-title":"Socioeconomic status, race and COPD health outcomes","volume":"65","author":"Eisner","year":"2011","journal-title":"J Epidemiol Community Health"},{"key":"10.1016\/j.jacr.2026.09.013_bib5","doi-asserted-by":"crossref","first-page":"3758","DOI":"10.21037\/jtd-20-3181","article-title":"Narrative review of socioeconomic and racial disparities in the treatment of early stage lung cancer","volume":"13","author":"Evans","year":"2021","journal-title":"J Thorac Dis"},{"key":"10.1016\/j.jacr.2026.09.013_bib6","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1007\/s40615-023-01625-2","article-title":"Disparities in lung cancer: a targeted literature review examining lung cancer screening, diagnosis, treatment, and survival outcomes in the United States","volume":"11","author":"Dwyer","year":"2024","journal-title":"J Racial Ethn Health Disparities"},{"key":"10.1016\/j.jacr.2026.09.013_bib7","doi-asserted-by":"crossref","first-page":"238","DOI":"10.4187\/respcare.10553","article-title":"The current state of health inequities in COPD","volume":"69","author":"Rea","year":"2024","journal-title":"Respir Care"},{"key":"10.1016\/j.jacr.2026.09.013_bib8","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1161\/CIRCULATIONAHA.117.029652","article-title":"Socioeconomic status and cardiovascular outcomes: challenges and interventions","volume":"137","author":"Schultz","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.jacr.2026.09.013_bib9","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1056\/NEJMoa1911793","article-title":"Reduced lung-cancer mortality with volume CT screening in a randomized trial","volume":"382","author":"de Koning","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacr.2026.09.013_bib10","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1056\/NEJMoa1102873","article-title":"Reduced lung-cancer mortality with low-dose computed tomographic screening","volume":"365","author":"Aberle","year":"2011","journal-title":"NEngl J Med"},{"key":"10.1016\/j.jacr.2026.09.013_bib11","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1164\/rccm.201502-0259OC","article-title":"Racial differences in outcomes within the National Lung Screening Trial. Implications for widespread implementation","volume":"192","author":"Tanner","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jacr.2026.09.013_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejca.2025.115264","article-title":"Paradigm shift in early detection: lung cancer screening to comprehensive CT screening","volume":"218","author":"Mulshine","year":"2025","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.jacr.2026.09.013_bib13","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.jacc.2018.05.027","article-title":"Coronary calcium score and cardiovascular risk","volume":"72","author":"Greenland","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacr.2026.09.013_bib14","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1164\/rccm.202002-0253OC","article-title":"Contribution of individual and neighborhood factors to racial disparities in respiratory outcomes","volume":"203","author":"Ejike","year":"2021","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jacr.2026.09.013_bib15","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.clinimag.2021.03.012","article-title":"The importance of low-dose CT screening to identify emphysema in asymptomatic participants with and without a prior diagnosis of COPD","volume":"78","author":"Steiger","year":"2021","journal-title":"Clin Imaging"},{"key":"10.1016\/j.jacr.2026.09.013_bib16","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.chest.2025.02.021","article-title":"Prevalence of airflow limitation and emphysema in lung cancer screening populations: a systematic review and meta-analysis","volume":"168","author":"Choi","year":"2025","journal-title":"Chest"},{"key":"10.1016\/j.jacr.2026.09.013_bib17","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1513\/AnnalsATS.202207-631PS","article-title":"Emphysema detection in the course of lung cancer screening: optimizing a rare opportunity to impact population health","volume":"20","author":"Mulshine","year":"2023","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.jacr.2026.09.013_bib18","doi-asserted-by":"crossref","DOI":"10.1148\/radiol.250949","article-title":"Emphysema at baseline low-dose CT lung cancer screening predicts death from chronic obstructive pulmonary disease and cardiovascular disease up to 25 years later","volume":"316","author":"Gonz\u00e1lez Guti\u00e9rrez","year":"2025","journal-title":"Radiology"},{"key":"10.1016\/j.jacr.2026.09.013_bib19","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/j.chest.2021.11.015","article-title":"Incidental findings on low-dose CT scan lung cancer screenings and deaths from respiratory diseases","volume":"161","author":"Pinsky","year":"2022","journal-title":"Chest"},{"key":"10.1016\/j.jacr.2026.09.013_bib20","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1513\/AnnalsATS.201911-857OC","article-title":"Prevalence, symptom burden, and underdiagnosis of chronic obstructive pulmonary disease in a lung cancer screening cohort","volume":"17","author":"Ruparel","year":"2020","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.jacr.2026.09.013_bib21","article-title":"ERS\/ESTS\/ESTRO\/ESR\/ESTI\/EFOMP statement on management of incidental findings from low dose CT screening for lung cancer","volume":"62","author":"O\u2019Dowd","year":"2023","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jacr.2026.09.013_bib22","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/RTI.0000000000000458","article-title":"Impact of significant coronary artery calcification reported on low-dose computed tomography lung cancer screening","volume":"35","author":"Mendoza","year":"2020","journal-title":"J Thorac Imaging"},{"key":"10.1016\/j.jacr.2026.09.013_bib23","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.chest.2025.03.031","article-title":"Coronary artery calcification identified on lung cancer screening CT scans: a scoping review","volume":"168","author":"Al-Antary","year":"2025","journal-title":"Chest"},{"key":"10.1016\/j.jacr.2026.09.013_bib24","first-page":"256","article-title":"Chronic obstructive pulmonary disease and asthma-patient characteristics and health impairment","volume":"11","author":"Pleasants","year":"2014","journal-title":"COPD"},{"key":"10.1016\/j.jacr.2026.09.013_bib25","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1161\/01.CIR.0000157730.94423.4B","article-title":"Ethnic differences in coronary calcification: the Multi-Ethnic Study of Atherosclerosis (MESA)","volume":"111","author":"Bild","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.jacr.2026.09.013_bib26","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/s12170-015-0447-4","article-title":"Differential outcomes by race and ethnicity in patients with coronary heart disease: a contemporary review","volume":"9","author":"Mochari-Greenberger","year":"2015","journal-title":"Curr Cardiovasc Risk Rep"},{"key":"10.1016\/j.jacr.2026.09.013_bib27","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.29741","article-title":"Analysis of eligibility for lung cancer screening by race after 2021 changes to US Preventive Services Task Force Screening Guidelines","volume":"5","author":"Pinheiro","year":"2022","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.jacr.2026.09.013_bib28","series-title":"2026 Qualified Clinical Data Registry (QCDR) measure specification details","year":"2026"},{"key":"10.1016\/j.jacr.2026.09.013_bib29","doi-asserted-by":"crossref","first-page":"e610","DOI":"10.1016\/j.jacl.2024.04.129","article-title":"Overcoming barriers to implementation: Improving incidental coronary calcium reporting on non-EKG gated chest CT scans","volume":"18","author":"Grant","year":"2024","journal-title":"J Clin Lipidol"},{"key":"10.1016\/j.jacr.2026.09.013_bib30","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1161\/CIRCULATIONAHA.122.062746","article-title":"Incidental coronary artery calcium: opportunistic screening of previous nongated chest computed tomography scans to improve statin rates (NOTIFY-1 Project)","volume":"147","author":"Sandhu","year":"2023","journal-title":"Circulation"},{"key":"10.1016\/j.jacr.2026.09.013_bib31","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jcct.2016.11.003","article-title":"2016 SCCT\/STR guidelines for coronary artery calcium scoring of noncontrast noncardiac chest CT scans: a report of the Society of Cardiovascular Computed Tomography and Society of Thoracic Radiology","volume":"11","author":"Hecht","year":"2017","journal-title":"J Cardiovasc Comput Tomogr"},{"key":"10.1016\/j.jacr.2026.09.013_bib32","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.chest.2025.02.031","article-title":"Interventions to improve adherence to clinical guidelines for the management and follow-up of pulmonary nodules: a systematic review","volume":"168","author":"Aunger","year":"2025","journal-title":"Chest"},{"key":"10.1016\/j.jacr.2026.09.013_bib33","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/j.chest.2025.06.006","article-title":"Components necessary for high-quality lung cancer screening: a 10-year update","volume":"168","author":"Barta","year":"2025","journal-title":"Chest"}],"container-title":["Journal of the American College of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1546144026004722?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1546144026004722?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:40:22Z","timestamp":1791499222000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1546144026004722"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":33,"alternative-id":["S1546144026004722"],"URL":"https:\/\/doi.org\/10.1016\/j.jacr.2026.09.013","relation":{},"ISSN":["1546-1440"],"issn-type":[{"value":"1546-1440","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Opportunistic Screening for Cardiovascular and Chronic Obstructive Pulmonary Disease Biomarkers and Implications for Downstream Care: A Retrospective Lung Cancer Screening Cohort Study","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacr.2026.09.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American College of Radiology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}