{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T12:56:43Z","timestamp":1791982603570,"version":"4.4.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.jad.2013.03.030","type":"journal-article","created":{"date-parts":[[2013,5,11]],"date-time":"2013-05-11T04:00:14Z","timestamp":1368244814000},"page":"231-236","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["The clinical utility of different quantitative methods for measuring treatment resistance in major depression"],"prefix":"10.1016","volume":"150","author":[{"given":"Hiral","family":"Hazari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Christmas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Matthews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2013.03.030_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jad.2004.10.003","article-title":"Evidence of cost-effective treatments for depression: a systematic review","volume":"84","author":"Barrett","year":"2005","journal-title":"Journal of Affective Disorders"},{"key":"10.1016\/j.jad.2013.03.030_bib2","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1177\/070674370705200108","article-title":"Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods","volume":"52","author":"Berlim","year":"2007","journal-title":"Canadian Journal of Psychiatry"},{"key":"10.1016\/j.jad.2013.03.030_bib3","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0006-3223(03)00231-2","article-title":"Diagnosis and definition of treatment-resistant depression","volume":"53","author":"Fava","year":"2003","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jad.2013.03.030_bib4","doi-asserted-by":"crossref","first-page":"177","DOI":"10.4088\/JCP.08m04309","article-title":"A multidimensional tool to quantify treatment resistance in depression: the Maudsley staging method","volume":"70","author":"Fekadu","year":"2009","journal-title":"Journal of Clinical Psychiatry"},{"key":"10.1016\/j.jad.2013.03.030_bib5","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.jad.2008.10.014","article-title":"What happens to patients with treatment-resistant depression? A systematic review of medium to long term outcome studies","volume":"116","author":"Fekadu","year":"2009","journal-title":"Journal of Affective Disorders"},{"key":"10.1016\/j.jad.2013.03.030_bib6","doi-asserted-by":"crossref","first-page":"952","DOI":"10.4088\/JCP.08m04728","article-title":"The Maudsley staging method for treatment-resistant depression: prediction of longer-term outcome and persistence of symptoms","volume":"70","author":"Fekadu","year":"2009","journal-title":"Journal of Clinical Psychiatry"},{"key":"10.1016\/j.jad.2013.03.030_bib7","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1001\/archpsyc.55.8.694","article-title":"A prospective 12-year study of subsyndromal and syndromal depressive symptoms in unipolar major depressive disorders","volume":"55","author":"Judd","year":"1998","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jad.2013.03.030_bib8","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1017\/S003329170300744X","article-title":"Remission and recurrence of depression in the maintenance era: long-term outcome in a Cambridge cohort","volume":"33","author":"Kennedy","year":"2003","journal-title":"Psychological Medicine"},{"key":"10.1016\/j.jad.2013.03.030_bib9","first-page":"245","article-title":"Factors influencing response to bilateral electroconvulsive therapy in major depression","volume":"7","author":"Kindler","year":"1991","journal-title":"Convulsive Therapy"},{"key":"10.1016\/j.jad.2013.03.030_bib10","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1001\/archpsyc.1991.01810320088015","article-title":"A polydiagnostic application of operational criteria in studies of psychotic illness. Development and reliability of the OPCRIT system","volume":"48","author":"McGuffin","year":"1991","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jad.2013.03.030_bib11","unstructured":"National Institute for Health and Clinical Excellence (NICE), 2009. Depression: the Treatment and Management of Depression in Adults. National Collaborating Centre for Mental Health, London."},{"key":"10.1016\/j.jad.2013.03.030_bib12","series-title":"Standards for Integrated Care Pathways for Mental Health","author":"NHS QIS","year":"2007"},{"key":"10.1016\/j.jad.2013.03.030_bib13","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1176\/appi.ajp.159.10.1746","article-title":"Adequacy of antidepressant treatment after discharge and the occurrence of suicidal acts in major depression: a prospective study","volume":"159","author":"Oquendo","year":"2002","journal-title":"American Journal of Psychiatry"},{"key":"10.1016\/j.jad.2013.03.030_bib14","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1136\/bmj.320.7226.15","article-title":"Effect of socioeconomic deprivation on waiting time for cardiac surgery: retrospective cohort study","volume":"320","author":"Pell","year":"2000","journal-title":"British Medical Journal"},{"key":"10.1016\/j.jad.2013.03.030_bib15","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1097\/01.jcp.0000169036.40755.16","article-title":"Empirical testing of two models for staging antidepressant treatment resistance","volume":"25","author":"Petersen","year":"2005","journal-title":"Journal of Clinical Psychopharmacology"},{"key":"10.1016\/j.jad.2013.03.030_bib16","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0165-1781(90)90098-P","article-title":"Medication resistance and clinical response to electroconvulsive therapy","volume":"31","author":"Prudic","year":"1990","journal-title":"Psychiatry Research"},{"key":"10.1016\/j.jad.2013.03.030_bib17","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jad.2011.02.020","article-title":"Staging methods for treatment resistant depression. A systematic review","volume":"137","author":"Ruh\u00e9","year":"2012","journal-title":"Journal of Affective Disorders"},{"key":"10.1016\/j.jad.2013.03.030_bib18","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1176\/ajp.2006.163.11.1905","article-title":"Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR(\u204e)D report","volume":"163","author":"Rush","year":"2006","journal-title":"American Journal of Psychiatry"},{"issue":"Suppl. 16","key":"10.1016\/j.jad.2013.03.030_bib19","first-page":"10","article-title":"The definition and meaning of treatment-resistant depression","volume":"62","author":"Sackeim","year":"2001","journal-title":"Journal of Clinical Psychiatry"},{"key":"10.1016\/j.jad.2013.03.030_bib20","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1192\/bjp.bp.110.083840","article-title":"Unrecognised bipolar disorder in primary care patients with depression","volume":"199","author":"Smith","year":"2011","journal-title":"British Journal of Psychiatry"},{"key":"10.1016\/j.jad.2013.03.030_bib21","series-title":"Version 16.0.2 for Microsoft Windows\u00ae","author":"SPSS","year":"2007"},{"key":"10.1016\/j.jad.2013.03.030_bib22","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1192\/bjp.181.4.284","article-title":"Randomised controlled trials investigating pharmacological and psychological interventions for treatment-refractory depression. Systematic review","volume":"181","author":"Stimpson","year":"2002","journal-title":"British Journal of Psychiatry"},{"issue":"Suppl 13","key":"10.1016\/j.jad.2013.03.030_bib23","first-page":"23","article-title":"When at first you don't succeed: sequential strategies for antidepressant nonresponders","volume":"58","author":"Thase","year":"1997","journal-title":"Journal of Clinical Psychiatry"},{"key":"10.1016\/j.jad.2013.03.030_bib24","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1001\/archpsyc.59.3.233","article-title":"Double-blind switch study of imipramine or sertraline treatment of antidepressant-resistant chronic depression","volume":"59","author":"Thase","year":"2002","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jad.2013.03.030_bib25","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1017\/S003329170003779X","article-title":"A multicentre inter-rater reliability study using the OPCRIT computerized diagnostic system","volume":"26","author":"Williams","year":"1996","journal-title":"Psychological Medicine"},{"key":"10.1016\/j.jad.2013.03.030_bib26","series-title":"International Statistical Classification of Diseases and Related Health Problems, 10th Revision","author":"World Health Organisation","year":"1992"}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032713002553?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032713002553?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T01:12:40Z","timestamp":1759021960000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032713002553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S0165032713002553"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2013.03.030","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The clinical utility of different quantitative methods for measuring treatment resistance in major depression","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2013.03.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}