{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T22:46:06Z","timestamp":1791758766336,"version":"4.3.4"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004484","name":"Tehran University of Medical Sciences and Health Services","doi-asserted-by":"publisher","award":["16074"],"award-info":[{"award-number":["16074"]}],"id":[{"id":"10.13039\/501100004484","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004484","name":"Tehran University of Medical Sciences and Health Services","doi-asserted-by":"publisher","award":["16074"],"award-info":[{"award-number":["16074"]}],"id":[{"id":"10.13039\/501100004484","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1016\/j.jad.2013.11.003","type":"journal-article","created":{"date-parts":[[2013,11,16]],"date-time":"2013-11-16T11:02:27Z","timestamp":1384599747000},"page":"216-222","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":118,"special_numbering":"C","title":["A randomized, double-blind, clinical trial comparing the efficacy and safety of Crocus sativus L. with fluoxetine for improving mild to moderate depression in post percutaneous coronary intervention patients"],"prefix":"10.1016","volume":"155","author":[{"given":"Nazila","family":"Shahmansouri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Farokhnia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed-Hesammeddin","family":"Abbasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Ebrahim","family":"Kassaian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad-Ali","family":"Noorbala Tafti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amirhossein","family":"Gougol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Habibeh","family":"Yekehtaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeedeh","family":"Forghani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehran","family":"Mahmoodian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sepideh","family":"Saroukhani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akram","family":"Arjmandi-Beglar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahin","family":"Akhondzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2013.11.003_bib1","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.pbb.2005.06.007","article-title":"Neuroprotection by crocetin in a hemi-parkinsonian rat model","volume":"81","author":"Ahmad","year":"2005","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.jad.2013.11.003_bib2","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0278-5846(02)00342-1","article-title":"Comparison of Lavandula angustifolia Mill. tincture and imipramine in the treatment of mild to moderate depression: a double-blind, randomized trial","volume":"27","author":"Akhondzadeh","year":"2003","journal-title":"Prog. Neuropsychopharmacolog. Biol. Psychiatry"},{"key":"10.1016\/j.jad.2013.11.003_bib3","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.pnpbp.2006.11.010","article-title":"Comparison of petal of Crocus sativus L. and fluoxetine in the treatment of depressed outpatients: a pilot double-blind randomized trial","volume":"31","author":"Akhondzadeh Basti","year":"2007","journal-title":"Prog. Neuropsychopharmacolog. Biol. Psychiatry"},{"key":"10.1016\/j.jad.2013.11.003_bib4","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1472-6882-4-12","article-title":"Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial [ISRCTN45683816]","volume":"4","author":"Akhondzadeh","year":"2004","journal-title":"BMC Complement. Altern. Med."},{"key":"10.1016\/j.jad.2013.11.003_bib5","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1111\/j.1365-2710.2009.01133.x","article-title":"Saffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16-week, randomized and placebo-controlled trial","volume":"35","author":"Akhondzadeh","year":"2010","journal-title":"J. Clin. Pharm. Ther."},{"key":"10.1016\/j.jad.2013.11.003_bib6","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/s00213-009-1706-1","article-title":"A 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer's disease","volume":"207","author":"Akhondzadeh","year":"2010","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.jad.2013.11.003_bib7","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1002\/ptr.1647","article-title":"Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo-controlled trial","volume":"19","author":"Akhondzadeh","year":"2005","journal-title":"Phytother. Res."},{"key":"10.1016\/j.jad.2013.11.003_bib8","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1592\/phco.23.6.754.32185","article-title":"Safety of antidepressant drugs in the patient with cardiac disease: a review of the literature","volume":"23","author":"Alvarez","year":"2003","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.jad.2013.11.003_bib9","doi-asserted-by":"crossref","first-page":"e1475","DOI":"10.4088\/JCP.12f08248","article-title":"Drug interactions in the treatment of depression in patients with ischemic heart disease","volume":"73","author":"Andrade","year":"2012","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2013.11.003_bib10","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S0002-9149(96)00380-3","article-title":"Depression and long-term mortality risk in patients with coronary artery disease","volume":"78","author":"Barefoot","year":"1996","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.jad.2013.11.003_bib11","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1080\/10408390902773003","article-title":"New applications and mechanisms of action of saffron and its important ingredients","volume":"50","author":"Bathaie","year":"2010","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.jad.2013.11.003_bib12","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD008012.pub3","article-title":"Psychological and pharmacological interventions for depression in patients with coronary artery disease","author":"Baumeister","year":"2011","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.jad.2013.11.003_bib13","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.neuroscience.2011.02.037","article-title":"Saffron extract and trans-crocetin inhibit glutamatergic synaptic transmission in rat cortical brain slices","volume":"180","author":"Berger","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.jad.2013.11.003_bib14","doi-asserted-by":"crossref","first-page":"3106","DOI":"10.1001\/jama.289.23.3106","article-title":"Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the enhancing recovery in coronary heart disease patients (ENRICHD) randomized trial","volume":"289","author":"Berkman","year":"2003","journal-title":"JAMA"},{"issue":"Suppl. 3","key":"10.1016\/j.jad.2013.11.003_bib15","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.3949\/ccjm.77.s3.03","article-title":"The American Heart Association science advisory on depression and coronary heart disease: an exploration of the issues raised","volume":"77","author":"Bigger","year":"2010","journal-title":"Cleve Clin. J. Med."},{"key":"10.1016\/j.jad.2013.11.003_bib16","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1016\/j.amjmed.2008.09.010","article-title":"Depression in patients with coronary heart disease","volume":"121","author":"Carney","year":"2008","journal-title":"Am. J. Med."},{"key":"10.1016\/j.jad.2013.11.003_bib17","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/0277-9536(91)90159-A","article-title":"Depression and acute myocardial infarction: a review and reinterpretation","volume":"32","author":"Fielding","year":"1991","journal-title":"Soc. Sci. Med."},{"key":"10.1016\/j.jad.2013.11.003_bib18","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.phymed.2009.08.009","article-title":"Preventive effect of crocin of Crocus sativus on hemodynamic, biochemical, histopathological and ultrastuctural alterations in isoproterenol-induced cardiotoxicity in rats","volume":"17","author":"Goyal","year":"2010","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jad.2013.11.003_bib19","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jad.2013.11.003_bib20","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.lfs.2005.02.006","article-title":"Effect of crocin on experimental atherosclerosis in quails and its mechanisms","volume":"77","author":"He","year":"2005","journal-title":"Life Sci."},{"key":"10.1016\/j.jad.2013.11.003_bib21","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1002\/ptr.4784","article-title":"Avicenna's (Ibn Sina) the Canon of medicine and saffron (Crocus sativus): a review","volume":"27","author":"Hosseinzadeh","year":"2013","journal-title":"Phytother. Res."},{"key":"10.1016\/j.jad.2013.11.003_bib22","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1002\/ptr.3044","article-title":"Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats","volume":"24","author":"Imenshahidi","year":"2010","journal-title":"Phytother. Res."},{"key":"10.1016\/j.jad.2013.11.003_bib23","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s00392-013-0568-z","article-title":"Persistent angina: highly prevalent and associated with long-term anxiety, depression, low physical functioning, and quality of life in stable angina pectoris","volume":"102","author":"Jespersen","year":"2013","journal-title":"Clin. Res. Cardiol."},{"key":"10.1016\/j.jad.2013.11.003_bib24","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s12012-010-9063-1","article-title":"The effect of saffron consumption on biochemical and histopathological heart indices of rats with myocardial infarction","volume":"10","author":"Joukar","year":"2010","journal-title":"Cardiovasc. Toxicol."},{"key":"10.1016\/j.jad.2013.11.003_bib25","first-page":"59","article-title":"Cardiovascular effects of saffron: an evidence-based review","volume":"6","author":"Kamalipour","year":"2011","journal-title":"J. Tehran Heart Cent."},{"key":"10.1016\/j.jad.2013.11.003_bib26","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1002\/hup.2282","article-title":"Saffron for treatment of fluoxetine-induced sexual dysfunction in women: randomized double-blind placebo-controlled study","volume":"28","author":"Kashani","year":"2013","journal-title":"Hum. Psychopharmacol."},{"key":"10.1016\/j.jad.2013.11.003_bib27","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S0022-3999(99)00102-6","article-title":"Depression in patients with cardiac disease: a practical review","volume":"48","author":"Lesperance","year":"2000","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.jad.2013.11.003_bib28","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1001\/archinte.160.9.1354","article-title":"Depression and 1-year prognosis in unstable angina","volume":"160","author":"Lesperance","year":"2000","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.jad.2013.11.003_bib29","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1002\/da.22051","article-title":"Treatment of depression in cardiovascular disease","volume":"30","author":"Mavrides","year":"2013","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.jad.2013.11.003_bib30","first-page":"56","article-title":"Cardioprotective effect of saffron extract and safranal in isoproterenol-induced myocardial infarction in wistar rats","volume":"16","author":"Mehdizadeh","year":"2013","journal-title":"Iran. J. Basic Med. Sci."},{"key":"10.1016\/j.jad.2013.11.003_bib31","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.genhosppsych.2011.02.007","article-title":"Prognostic association of depression following myocardial infarction with mortality and cardiovascular events: a meta-analysis of 25 years of research","volume":"33","author":"Meijer","year":"2011","journal-title":"Gen. Hosp. Psychiatry"},{"key":"10.1016\/j.jad.2013.11.003_bib32","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/s00213-012-2729-6","article-title":"Effect of saffron on fluoxetine-induced sexual impairment in men: randomized double-blind placebo-controlled trial","volume":"223","author":"Modabbernia","year":"2012","journal-title":"Psychopharmacol. (Berl)"},{"key":"10.1016\/j.jad.2013.11.003_bib33","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1016\/j.phymed.2008.06.003","article-title":"Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers","volume":"15","author":"Modaghegh","year":"2008","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jad.2013.11.003_bib34","doi-asserted-by":"crossref","first-page":"C893","DOI":"10.1111\/j.1750-3841.2012.02803.x","article-title":"Radical scavenging activity and LC\u2013MS metabolic profiling of petals, stamens, and flowers of Crocus sativus L","volume":"77","author":"Montoro","year":"2012","journal-title":"J. Food Sci."},{"key":"10.1016\/j.jad.2013.11.003_bib35","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.phymed.2006.08.006","article-title":"Crocus sativus L. (petal) in the treatment of mild-to-moderate depression: a double-blind, randomized and placebo-controlled trial","volume":"13","author":"Moshiri","year":"2006","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jad.2013.11.003_bib36","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jep.2004.11.004","article-title":"Hydro-alcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression: a double-blind, randomized pilot trial","volume":"97","author":"Noorbala","year":"2005","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jad.2013.11.003_bib37","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.bbr.2011.01.007","article-title":"Memory enhancing effects of saffron in aged mice are correlated with antioxidant protection","volume":"219","author":"Papandreou","year":"2011","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.jad.2013.11.003_bib38","doi-asserted-by":"crossref","first-page":"252","DOI":"10.4306\/pi.2012.9.3.252","article-title":"Effects of percutaneous coronary intervention on depressive symptoms in chronic stable angina patients","volume":"9","author":"Park","year":"2012","journal-title":"Psychiatry Invest."},{"key":"10.1016\/j.jad.2013.11.003_bib39","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.bbr.2007.06.001","article-title":"Effects of the active constituents of Crocus sativus L., crocins on recognition and spatial rats' memory","volume":"183","author":"Pitsikas","year":"2007","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.jad.2013.11.003_bib40","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/j.amjcard.2010.11.017","article-title":"Meta-analysis of selective serotonin reuptake inhibitors in patients with depression and coronary heart disease","volume":"107","author":"Pizzi","year":"2011","journal-title":"Am. J. Cardiol."},{"issue":"Suppl. 3","key":"10.1016\/j.jad.2013.11.003_bib41","first-page":"439S","article-title":"Cardiac effects of antidepressant drugs. A comparison of the tricyclic antidepressants and fluvoxamine","volume":"15","author":"Roos","year":"1983","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jad.2013.11.003_bib42","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.etp.2010.11.013","article-title":"Crocus sativus L. (saffron) attenuates isoproterenol-induced myocardial injury via preserving cardiac functions and strengthening antioxidant defense system","volume":"64","author":"Sachdeva","year":"2012","journal-title":"Exp. Toxicol. Pathol."},{"key":"10.1016\/j.jad.2013.11.003_bib43","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s10354-007-0428-4","article-title":"Saffron in phytotherapy: pharmacology and clinical uses","volume":"157","author":"Schmidt","year":"2007","journal-title":"Wien. Med. Wochenschr."},{"key":"10.1016\/j.jad.2013.11.003_bib44","doi-asserted-by":"crossref","first-page":"C1162","DOI":"10.1111\/j.1750-3841.2012.02926.x","article-title":"Increasing the applications of Crocus sativus flowers as natural antioxidants","volume":"77","author":"Serrano-Diaz","year":"2012","journal-title":"J. Food Sci."},{"key":"10.1016\/j.jad.2013.11.003_bib45","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.ejphar.2006.05.038","article-title":"Mechanism of hypolipidemic effect of crocin in rats: crocin inhibits pancreatic lipase","volume":"543","author":"Sheng","year":"2006","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jad.2013.11.003_bib46","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1002\/ptr.4836","article-title":"Effect of crocin on the insulin resistance and lipid profile of streptozotocin-induced diabetic rats","volume":"27","author":"Shirali","year":"2013","journal-title":"Phytother. Res."},{"key":"10.1016\/j.jad.2013.11.003_bib47","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1159\/000119692","article-title":"Depression and heart disease: therapeutic implications","volume":"111","author":"Somberg","year":"2008","journal-title":"Cardiology"},{"key":"10.1016\/j.jad.2013.11.003_bib48","doi-asserted-by":"crossref","first-page":"200","DOI":"10.4103\/0973-7847.70919","article-title":"Crocus sativus L.: a comprehensive review","volume":"4","author":"Srivastava","year":"2010","journal-title":"Pharmacogn. Rev."},{"key":"10.1016\/j.jad.2013.11.003_bib49","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.jpsychores.2006.12.009","article-title":"Comorbid depression and health-related quality of life in patients with coronary artery disease","volume":"62","author":"Stafford","year":"2007","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.jad.2013.11.003_bib50","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1592\/phco.30.3.304","article-title":"Impact and clinical management of depression in patients with coronary artery disease","volume":"30","author":"Summers","year":"2010","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.jad.2013.11.003_bib51","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.4088\/JCP.09m05810blu","article-title":"Major depressive disorder predicts completion, adherence, and outcomes in cardiac rehabilitation: a prospective cohort study of 195 patients with coronary artery disease","volume":"72","author":"Swardfager","year":"2011","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2013.11.003_bib52","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1001\/archpsyc.62.7.792","article-title":"Effects of antidepressant medication on morbidity and mortality in depressed patients after myocardial infarction","volume":"62","author":"Taylor","year":"2005","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2013.11.003_bib53","doi-asserted-by":"crossref","first-page":"58","DOI":"10.3109\/19390211.2011.547666","article-title":"An evidence-based systematic review of saffron (Crocus sativus) by the natural standard research collaboration","volume":"8","author":"Ulbricht","year":"2011","journal-title":"J. Diet. Suppl."},{"key":"10.1016\/j.jad.2013.11.003_bib54","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s11418-009-0360-6","article-title":"Antidepressant properties of bioactive fractions from the extract of Crocus sativus L","volume":"64","author":"Wang","year":"2010","journal-title":"J. Nat. Med."},{"key":"10.1016\/j.jad.2013.11.003_bib55","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.amjcard.2006.03.051","article-title":"Use of complementary therapies in patients with cardiovascular disease","volume":"98","author":"Yeh","year":"2006","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.jad.2013.11.003_bib56","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.bcp.2005.07.034","article-title":"Suppression of vascular cell adhesion molecule-1 expression by crocetin contributes to attenuation of atherosclerosis in hypercholesterolemic rabbits","volume":"70","author":"Zheng","year":"2005","journal-title":"Biochem. Pharmacol."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032713007970?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032713007970?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T01:13:09Z","timestamp":1759021989000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032713007970"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2]]},"references-count":56,"alternative-id":["S0165032713007970"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2013.11.003","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2014,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A randomized, double-blind, clinical trial comparing the efficacy and safety of Crocus sativus L. with fluoxetine for improving mild to moderate depression in post percutaneous coronary intervention patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2013.11.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}