{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T13:00:20Z","timestamp":1788872420972,"version":"build-2803163510"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"IRP-NIMH-NIH","award":["NCT00088699"],"award-info":[{"award-number":["NCT00088699"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jad-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.jad.2014.09.015","type":"journal-article","created":{"date-parts":[[2014,10,16]],"date-time":"2014-10-16T14:08:25Z","timestamp":1413468505000},"page":"307-311","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Shank3 as a potential biomarker of antidepressant response to ketamine and its neural correlates in bipolar depression"],"prefix":"10.1016","volume":"172","author":[{"given":"Robin","family":"Ortiz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark J.","family":"Niciu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nada","family":"Lukkahati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leorey N.","family":"Saligan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison C.","family":"Nugent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Luckenbaugh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Machado-Vieira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Carlos A.","family":"Zarate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2014.09.015_bib1","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.neuroscience.2013.03.030","article-title":"Rearrangement of the dendritic morphology in limbic regions and altered exploratory behavior in a rat model of autism spectrum disorder","volume":"241","author":"Bringas","year":"2013","journal-title":"Neuroscience"},{"key":"10.1016\/j.jad.2014.09.015_bib2","doi-asserted-by":"crossref","first-page":"R43","DOI":"10.1186\/gb-2012-13-6-r43","article-title":"Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood","volume":"13","author":"Davies","year":"2012","journal-title":"Genome Biol."},{"key":"10.1016\/j.jad.2014.09.015_bib3","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1001\/archgenpsychiatry.2007.37","article-title":"Glutamate and the neural basis of the subjective effects of ketamine: a pharmaco-magnetic resonance imaging study","volume":"65","author":"Deakin","year":"2008","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2014.09.015_bib4","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1001\/archgenpsychiatry.2010.90","article-title":"A randomized add-on trial of an N-methyl-d-aspartate antagonist in treatment-resistant bipolar depression","volume":"67","author":"Diazgranados","year":"2010","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2014.09.015_bib5","doi-asserted-by":"crossref","first-page":"11","DOI":"10.31887\/DCNS.2014.16.1\/rduman","article-title":"Pathophysiology of depression and innovative treatments: remodeling glutamatergic synaptic connections","volume":"16","author":"Duman","year":"2014","journal-title":"Dialogues Clin. Neurosci."},{"key":"10.1016\/j.jad.2014.09.015_bib6","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/dneu.22128","article-title":"The emerging role of SHANK genes in neuropsychiatric disorders","volume":"74","author":"Guilmatre","year":"2014","journal-title":"Dev. Neurobiol."},{"key":"10.1016\/j.jad.2014.09.015_bib7","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/nature12630","article-title":"SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties","volume":"503","author":"Han","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.jad.2014.09.015_bib8","doi-asserted-by":"crossref","first-page":"18448","DOI":"10.1523\/JNEUROSCI.3017-13.2013","article-title":"Loss of predominant shank3 isoforms results in hippocampus-dependent impairments in behavior and synaptic transmission","volume":"33","author":"Kouser","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jad.2014.09.015_bib1001","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.molcel.2013.02.014","article-title":"Altered social behavior and neuronal development in mice lack the Uba6-Use1 ubiquitin transfer system","volume":"50","author":"Lee","year":"2013","journal-title":"Molecular Cell"},{"key":"10.1016\/j.jad.2014.09.015_bib9","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.neuroscience.2012.09.057","article-title":"Remodeling of axo-spinous synapses in the pathophysiology and treatment of depression","volume":"251","author":"Licznerski","year":"2013","journal-title":"Neuroscience"},{"key":"10.1016\/j.jad.2014.09.015_bib10","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/da.22224","article-title":"Developing biomarkers in mood disorders research through the use of rapid-acting antidepressants","volume":"31","author":"Niciu","year":"2014","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.jad.2014.09.015_bib11","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.pscychresns.2013.05.004","article-title":"Reduced thalamic volumes in major depressive disorder","volume":"213","author":"Nugent","year":"2013","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jad.2014.09.015_bib12","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/bdi.12118","article-title":"Neural correlates of rapid antidepressant response to ketamine in bipolar disorder","volume":"16","author":"Nugent","year":"2014","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.jad.2014.09.015_bib13","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1002\/hbm.22068","article-title":"Automated subcortical segmentation using FIRST: test-retest reliability, interscanner reliability, and comparison to manual segmentation","volume":"34","author":"Nugent","year":"2013","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.jad.2014.09.015_bib1002","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/nature09965","article-title":"Shank3 mutant mice display autistic-like behaviours and striatal dysfunction","volume":"472","author":"Peca","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.jad.2014.09.015_bib14","doi-asserted-by":"crossref","first-page":"e38971","DOI":"10.1371\/journal.pone.0038971","article-title":"Dendritic morphology of hippocampal and amygdalar neurons in adolescent mice is resilient to genetic differences in stress reactivity","volume":"7","author":"Pillai","year":"2012","journal-title":"PloS One"},{"key":"10.1016\/j.jad.2014.09.015_bib15","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.neuroscience.2010.08.041","article-title":"Proline-rich synapse-associated protein-1 and 2 (ProSAP1\/Shank2 and ProSAP2\/Shank3)-scaffolding proteins are also present in postsynaptic specializations of the peripheral nervous system","volume":"171","author":"Raab","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.jad.2014.09.015_bib16","doi-asserted-by":"crossref","first-page":"3560","DOI":"10.1523\/JNEUROSCI.4354-04.2005","article-title":"Shank expression is sufficient to induce functional dendritic spine synapses in spiny neurons","volume":"25","author":"Roussignol","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jad.2014.09.015_bib17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.5498\/wjp.v2.i3.49","article-title":"Neuroplasticity and major depression, the role of modern antidepressant drugs","volume":"2","author":"Serafini","year":"2012","journal-title":"World J. Psychiatry"},{"key":"10.1016\/j.jad.2014.09.015_bib18","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1176\/appi.ajp.160.8.1516","article-title":"Untreated depression and hippocampal volume loss","volume":"160","author":"Sheline","year":"2003","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2014.09.015_bib19","doi-asserted-by":"crossref","first-page":"8235","DOI":"10.1073\/pnas.96.14.8235","article-title":"Determination of the rate of the glutamate\/glutamine cycle in the human brain by in vivo 13C NMR","volume":"96","author":"Shen","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jad.2014.09.015_bib20","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jad.2012.09.003","article-title":"A magnetic resonance imaging study of hippocampal, amygdala and subgenual prefrontal cortex volumes in major depression subtypes: melancholic versus psychotic depression","volume":"146","author":"Vassilopoulou","year":"2013","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.jad.2014.09.015_bib21","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.biopsych.2011.12.010","article-title":"Replication of ketamine\u05f3s antidepressant efficacy in bipolar depression: a randomized controlled add-on trial","volume":"71","author":"Zarate","year":"2012","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2014.09.015_bib22","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1001\/archpsyc.63.8.856","article-title":"A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression","volume":"63","author":"Zarate","year":"2006","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2014.09.015_bib23","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1016\/j.jpsychires.2011.06.006","article-title":"P11 expression and PET in bipolar disorders","volume":"45","author":"Zhang","year":"2011","journal-title":"J. Psychiatr Res."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032714005692?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032714005692?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T21:54:31Z","timestamp":1650405271000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032714005692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":25,"alternative-id":["S0165032714005692"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2014.09.015","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Shank3 as a potential biomarker of antidepressant response to ketamine and its neural correlates in bipolar depression","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2014.09.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}