{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:23:07Z","timestamp":1790256187717,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000009","name":"NIH","doi-asserted-by":"publisher","award":["R01 MH080912"],"award-info":[{"award-number":["R01 MH080912"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hartford Hospital Open Competition Grant"},{"DOI":"10.13039\/501100000024","name":"Canadian Institute of Health Research","doi-asserted-by":"publisher","award":["CIHR-111257"],"award-info":[{"award-number":["CIHR-111257"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000155","name":"Social Sciences and Humanities Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000155","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1016\/j.jad.2018.11.008","type":"journal-article","created":{"date-parts":[[2018,11,3]],"date-time":"2018-11-03T05:38:00Z","timestamp":1541223480000},"page":"394-402","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Altered amygdala circuits underlying valence processing among manic and depressed phases in bipolar adults"],"prefix":"10.1016","volume":"245","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5380-5521","authenticated-orcid":false,"given":"Vincent","family":"Man","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"June","family":"Gruber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Glahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Cunningham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jad.2018.11.008_bib0001","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.biopsych.2009.09.027","article-title":"Elevated amygdala activity to sad facial expressions: A state marker of bipolar but not unipolar depression","volume":"67","author":"Almeida","year":"2010","journal-title":"Biol. Psychiatry."},{"key":"10.1016\/j.jad.2018.11.008_bib0002","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.biopsych.2009.03.024","article-title":"Abnormal amygdala-prefrontal effective connectivity to happy faces differentiates bipolar from major depression","volume":"66","author":"Almeida","year":"2009","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2018.11.008_bib0003","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/j.biopsych.2005.02.021","article-title":"Activity and connectivity of brain mood regulating circuit in depression: A functional magnetic resonance study","volume":"57","author":"Anand","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2018.11.008_bib0004","unstructured":"Andersson, J.L., Jenkinson, M., Smith, S., 2007. Non-linear registration, aka spatial normalization. FMRIB technical report TR07JA2. FMRIB Analysis Group of the University of Oxford, 2."},{"key":"10.1016\/j.jad.2018.11.008_bib0005","doi-asserted-by":"crossref","first-page":"4311","DOI":"10.1523\/JNEUROSCI.20-11-04311.2000","article-title":"Control of response selection by reinforcer value requires interaction of amygdala and orbital prefrontal cortex","volume":"20","author":"Baxter","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jad.2018.11.008_bib0006","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/j.1399-5618.2008.00648.x","article-title":"A preliminary study of increased amygdala activation to positive affective stimuli in mania","volume":"11","author":"Bermpohl","year":"2009","journal-title":"Bipolar. Disord."},{"key":"10.1016\/j.jad.2018.11.008_bib0007","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/j.1467-9280.2008.02061.x","article-title":"Affective flexibility: Evaluative processing goals shape amygdala activity","volume":"19","author":"Cunningham","year":"2008","journal-title":"Psychol. Sci."},{"key":"10.1016\/j.jad.2018.11.008_bib0008","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1089\/brain.2016.0475","article-title":"FMRI clustering in AFNI: False Positive Rates Redux","volume":"7","author":"Cox","year":"2017","journal-title":"Brain. Connect."},{"key":"10.1016\/j.jad.2018.11.008_bib0009","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3758\/CABN.3.1.27","article-title":"Dorsal striatum responses to reward and punishment: Effects of valence and magnitude manipulations","volume":"3","author":"Delgado","year":"2003","journal-title":"Cogn. Affect. Behav. Neurosci."},{"key":"10.1016\/j.jad.2018.11.008_bib0010","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.neuroimage.2006.01.021","article-title":"An automated labeling system for subdividing the human cerebral cortex on MRI scans into Gyral based regions of interest","volume":"31","author":"Desikan","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2018.11.008_bib0011","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s10608-015-9679-3","article-title":"Feeling good and taking a chance? Associations of hypomania risk with cognitive and behavioral risk taking","volume":"39","author":"Devlin","year":"2015","journal-title":"Cognit. Ther. Res."},{"key":"10.1016\/j.jad.2018.11.008_bib0012","article-title":"Cluster failure: Why fMRI inferences for spatial extent have inflated false-positive rates","volume":"28","author":"Eklund","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.jad.2018.11.008_bib0013","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/j.biopsych.2004.03.007","article-title":"Abnormal ventral frontal response during performance of an affective go\/no go task in patients with mania","volume":"55","author":"Elliott","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2018.11.008_bib0014","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1001\/archpsyc.59.7.597","article-title":"The neural basis of mood-congruent processing biases in depression","volume":"59","author":"Elliott","year":"2002","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.jad.2018.11.008_bib0015","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1006\/nimg.1997.0291","article-title":"Psychophysiological and modulatory interactions in neuroimaging","volume":"6","author":"Friston","year":"1997","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2018.11.008_bib0016","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1001\/archgenpsychiatry.2009.184","article-title":"Neurocognitive endophenotypes for bipolar disorder identified in multiplex multigenerational families","volume":"67","author":"Glahn","year":"2010","journal-title":"Arch. Gen. Psychiatry."},{"key":"10.1016\/j.jad.2018.11.008_bib0017","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1002\/ajmg.b.30446","article-title":"Adjudicating neurocognitive endophenotypes for schizophrenia","volume":"144","author":"Glahn","year":"2007","journal-title":"Am. J. Med. Genet. B. Neuropsychiatr. Genet."},{"key":"10.1016\/j.jad.2018.11.008_bib0018","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.neuroimage.2009.06.060","article-title":"Accurate and robust brain image alignment using boundary-based registration","volume":"48","author":"Greve","year":"2009","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2018.11.008_bib0019","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1002\/cpp.776","article-title":"A review and synthesis of positive emotion and reward disturbance in bipolar disorder","volume":"18","author":"Gruber","year":"2011","journal-title":"Clin. Psychol. Psychother."},{"key":"10.1016\/j.jad.2018.11.008_bib0020","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1037\/1528-3542.8.1.23","article-title":"Risk for mania and positive emotional responding: Too much of a good thing?","volume":"8","author":"Gruber","year":"2008","journal-title":"Emotion"},{"key":"10.1016\/j.jad.2018.11.008_bib0021","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/00001756-200201210-00008","article-title":"Positive and negative emotional verbal stimuli elicit activity in the left amygdala","volume":"13","author":"Hamann","year":"2002","journal-title":"Neuroreport"},{"key":"10.1016\/j.jad.2018.11.008_bib0022","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jad.2018.11.008_bib0023","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1176\/appi.ajp.2010.09091379","article-title":"Research domain criteria (RDoC): Toward a new classification framework for research on mental disorders","volume":"167","author":"Insel","year":"2010","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2018.11.008_bib0024","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1038\/nature14188","article-title":"From circuits to behaviour in the amygdala","volume":"517","author":"Janak","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.jad.2018.11.008_bib0025","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1006\/nimg.2002.1132","article-title":"Improved optimisation for the robust and accurate linear registration and motion correction of brain images","volume":"17","author":"Jenkinson","year":"2002","journal-title":"NeuroImage"},{"key":"10.1016\/j.jad.2018.11.008_bib0026","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S1361-8415(01)00036-6","article-title":"A global optimisation method for robust affine registration of brain images","volume":"5","author":"Jenkinson","year":"2001","journal-title":"Med. Image. Anal."},{"key":"10.1016\/j.jad.2018.11.008_bib0027","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.neuroimage.2008.03.059","article-title":"Functional grouping and cortical\u2013subcortical interactions in emotion: A meta-analysis of neuroimaging studies","volume":"42","author":"Kober","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2018.11.008_bib0028","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1503\/jpn.120117","article-title":"Functional connectivity between the amygdala and prefrontal cortex in medication-naive individuals with major depressive disorder","volume":"38","author":"Kong","year":"2013","journal-title":"J. Psychiatry. Neurosci."},{"key":"10.1016\/j.jad.2018.11.008_bib0029","unstructured":"Lang, P.J., Bradley, M.M., Cuthbert, B.N., 2008. International affective picture system (IAPS): Affective ratings of pictures and instruction manual. Technical Report A-8."},{"key":"10.1016\/j.jad.2018.11.008_bib0030","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.biopsych.2003.11.017","article-title":"Subcortical and ventral prefrontal cortical neural responses to facial expressions distinguish patients with bipolar disorder and major depression","volume":"55","author":"Lawrence","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2018.11.008_bib0031","doi-asserted-by":"crossref","first-page":"R868","DOI":"10.1016\/j.cub.2007.08.005","article-title":"The amygdala","volume":"17","author":"LeDoux","year":"2007","journal-title":"Curr. Biol."},{"key":"10.1016\/j.jad.2018.11.008_bib0032","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1176\/appi.ajp.159.2.302","article-title":"Impaired recognition of facial emotion in mania","volume":"159","author":"Lembke","year":"2002","journal-title":"Am. J. Psychiatry."},{"key":"10.1016\/j.jad.2018.11.008_bib0033","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/j.neubiorev.2010.12.012","article-title":"Common and distinct networks underlying reward valence and processing stages: A meta-analysis of functional neuroimaging studies","volume":"35","author":"Liu","year":"2011","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.jad.2018.11.008_bib0034","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1016\/j.neuroimage.2011.08.076","article-title":"Deconvolving BOLD activation in event-related designs for multivoxel pattern classification analyses","volume":"59","author":"Mumford","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2018.11.008_bib0035","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1001\/archpsyc.1994.03950110009002","article-title":"Diagnostic interview for genetic studies: rationale, unique features, and training","volume":"51","author":"Nurnberger","year":"1994","journal-title":"Arch. Gen. Psychiat."},{"key":"10.1016\/j.jad.2018.11.008_bib0036","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1399-5618.2012.01012.x","article-title":"Waiting to win: elevated striatal and orbitofrontal cortical activity during reward anticipation in euthymic bipolar disorder adults","volume":"14","author":"Nusslock","year":"2012","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.jad.2018.11.008_bib0037","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1176\/appi.ajp.2014.13081008","article-title":"A critical appraisal of neuroimaging studies of bipolar disorder: toward a new conceptualization of underlying neural circuitry and a road map for future research","volume":"171","author":"Phillips","year":"2014","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jad.2018.11.008_bib0038","unstructured":"Pinheiro, J., Bates, D., DebRoy, S., Sarkar, D., Team, R.C., 2015. NLME: Linear and Nonlinear Mixed Effects Models. R package version 3, 1\u2013120."},{"key":"10.1016\/j.jad.2018.11.008_bib0039","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1016\/j.neuroimage.2011.10.018","article-title":"Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion","volume":"59","author":"Power","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2018.11.008_bib0040","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.tics.2011.12.011","article-title":"Neural circuits underlying the pathophysiology of mood disorders","volume":"16","author":"Price","year":"2012","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.jad.2018.11.008_bib0041","doi-asserted-by":"crossref","first-page":"8900","DOI":"10.1073\/pnas.0603246103","article-title":"Limbic hyperactivation during processing of neutral facial expressions in children with bipolar disorder","volume":"103","author":"Rich","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.jad.2018.11.008_bib0042","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.neuroimage.2004.06.035","article-title":"Measuring functional connectivity during distinct stages of a cognitive task","volume":"23","author":"Rissman","year":"2004","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2018.11.008_bib0043","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1038\/sj.mp.4001585","article-title":"The functional neuroanatomy of bipolar disorder: A review of neuroimaging findings","volume":"10","author":"Strakowski","year":"2005","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jad.2018.11.008_bib0044","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1038\/npp.2014.39","article-title":"Disturbed anterior prefrontal control of the mesolimbic reward system and increased impulsivity in bipolar disorder","volume":"39","author":"Trost","year":"2014","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jad.2018.11.008_bib0045","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.neuroimage.2011.07.044","article-title":"The influence of head motion on intrinsic functional connectivity MRI","volume":"59","author":"Van Dijk","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.jad.2018.11.008_bib0046","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.biopsych.2009.11.025","article-title":"Abnormal left and right amygdala-orbitofrontal cortical functional connectivity to emotional faces: State versus trait vulnerability markers of depression in bipolar disorder","volume":"67","author":"Versace","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2018.11.008_bib0047","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.biopsych.2009.03.023","article-title":"Functional and structural connectivity between the perigenual anterior cingulate and amygdala in bipolar disorder","volume":"66","author":"Wang","year":"2009","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.jad.2018.11.008_bib0048","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/YCO.0000000000000122","article-title":"Reward processing dysfunction in major depression, bipolar disorder and schizophrenia","volume":"28","author":"Whitton","year":"2015","journal-title":"Curr. Opin. Psychiatry"},{"key":"10.1016\/j.jad.2018.11.008_bib0049","first-page":"429","article-title":"A rating scale for mania: Reliability, validity and sensitivity","volume":"133","author":"Young","year":"1978","journal-title":"BJPsych."},{"key":"10.1016\/j.jad.2018.11.008_bib0050","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1109\/42.906424","article-title":"Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm","volume":"20","author":"Zhang","year":"2001","journal-title":"IEEE. Trans. Med. Imaging."}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032718310681?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032718310681?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T11:40:12Z","timestamp":1565264412000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032718310681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":50,"alternative-id":["S0165032718310681"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2018.11.008","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2019,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Altered amygdala circuits underlying valence processing among manic and depressed phases in bipolar adults","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2018.11.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}