{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:42:11Z","timestamp":1790383331520,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002102","name":"King's Health Partners","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002102","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Affective Disorders"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.jad.2019.09.078","type":"journal-article","created":{"date-parts":[[2019,9,30]],"date-time":"2019-09-30T18:36:15Z","timestamp":1569868575000},"page":"91-102","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"special_numbering":"C","title":["Chronotherapy for the rapid treatment of depression: A meta-analysis"],"prefix":"10.1016","volume":"261","author":[{"given":"Clara","family":"Humpston","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Benedetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Serfaty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Markham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Hodsoll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan H.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Veale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.jad.2019.09.078_bib0001","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0022-3956(01)00034-6","article-title":"Sleep phase advance and lithium to sustain the antidepressant effect of total sleep deprivation in bipolar depression: new findings supporting the internal coincidence model","volume":"35","author":"Benedetti","year":"2001","journal-title":"J. Psychiatr. Res."},{"issue":"12","key":"10.1016\/j.jad.2019.09.078_bib0002","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.4088\/JCP.v66n1207","article-title":"Combined total sleep deprivation and light therapy in the treatment of drug-resistant bipolar depression: acute response and long-term remission rates","volume":"66","author":"Benedetti","year":"2005","journal-title":"J. Clin. Psychiatry"},{"issue":"2","key":"10.1016\/j.jad.2019.09.078_bib0003","doi-asserted-by":"crossref","first-page":"133","DOI":"10.4088\/JCP.13m08455","article-title":"Rapid treatment response of suicidal symptoms to lithium, sleep deprivation, and light therapy (chronotherapy) in drug-resistant bipolar depression","volume":"75","author":"Benedetti","year":"2014","journal-title":"J. Clin. Psychiatry"},{"issue":"6","key":"10.1016\/j.jad.2019.09.078_bib0004","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1176\/ajp.154.6.870","article-title":"Sleep deprivation combined with consecutive sleep phase advance as a fast-acting therapy in depression: an open pilot trial in medicated and unmedicated patients","volume":"154","author":"Berger","year":"1997","journal-title":"Am. J. Psychiatry"},{"issue":"8","key":"10.1016\/j.jad.2019.09.078_bib0005","doi-asserted-by":"crossref","first-page":"e1020","DOI":"10.4088\/JCP.16r11332","article-title":"Meta-Analysis of the antidepressant effects of acute sleep deprivation","volume":"78","author":"Boland","year":"2017","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.jad.2019.09.078_bib0006","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/j.1600-0447.1988.tb08553.x","article-title":"Prediction of clinical change by ethological methods","volume":"341","author":"Bouhuys","year":"1988","journal-title":"Acta Psychiatr. Scand. Suppl."},{"issue":"12","key":"10.1016\/j.jad.2019.09.078_bib0008","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1016\/j.jclinepi.2008.12.010","article-title":"Not only randomized controlled trials, but also case series should be considered in systematic reviews of rapidly developing technologies","volume":"62","author":"Chambers","year":"2009","journal-title":"J. Clin. Epidemiol."},{"issue":"1","key":"10.1016\/j.jad.2019.09.078_bib0009","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0165-1781(00)00164-5","article-title":"Total sleep deprivation combined with lithium and light therapy in the treatment of bipolar depression: replication of main effects and interaction","volume":"95","author":"Colombo","year":"2000","journal-title":"Psychiatry Res."},{"issue":"9","key":"10.1016\/j.jad.2019.09.078_bib0010","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1080\/07420528.2018.1469034","article-title":"Chronotype influences response to antidepressant chronotherapy in bipolar patients","volume":"35","author":"Dallaspezia","year":"2018","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.jad.2019.09.078_bib0011","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.psychres.2016.04.104","article-title":"Antidepressant chronotherapy in a group of drug free outpatients","volume":"241","author":"Dallaspezia","year":"2016","journal-title":"Psychiatry Res."},{"issue":"1\u20132","key":"10.1016\/j.jad.2019.09.078_bib0012","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jad.2012.06.022","article-title":"Total sleep deprivation followed by sleep phase advance and bright light therapy in drug-resistant mood disorders","volume":"144","author":"Echizenya","year":"2013","journal-title":"J. Affect. Disord."},{"issue":"2","key":"10.1016\/j.jad.2019.09.078_bib0014","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s00787-015-0720-6","article-title":"Chronotherapeutic treatments for depression in youth","volume":"25","author":"Gest","year":"2016","journal-title":"Eur. Child Adolesc. Psychiatry"},{"issue":"4","key":"10.1016\/j.jad.2019.09.078_bib0015","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1176\/appi.ajp.162.4.656","article-title":"The efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis of the evidence","volume":"162","author":"Golden","year":"2005","journal-title":"Am. J. Psychiatry"},{"issue":"5","key":"10.1016\/j.jad.2019.09.078_bib0016","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1097\/01.pra.0000419822.69914.8e","article-title":"Outpatient triple chronotherapy for bipolar depression: case report","volume":"18","author":"Gottlieb","year":"2012","journal-title":"J. Psychiatr. Pract."},{"key":"10.1016\/j.jad.2019.09.078_bib0017","doi-asserted-by":"crossref","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The cochrane collaboration's tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.jad.2019.09.078_bib0018","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1089\/cap.2018.0063","article-title":"Prospective, open trial of adjunctive triple chronotherapy for the acute treatment of depression in adolescent inpatients","volume":"29","author":"Hurd","year":"2019","journal-title":"J. Child Adolesc. Psychopharmacol."},{"issue":"9","key":"10.1016\/j.jad.2019.09.078_bib0019","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1080\/07420528.2018.1468341","article-title":"Predictors of response to combined wake and light therapy in treatment-resistant inpatients with depression","volume":"35","author":"Kragh","year":"2018","journal-title":"Chronobiol. Int."},{"issue":"6","key":"10.1016\/j.jad.2019.09.078_bib0020","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/acps.12741","article-title":"Wake and light therapy for moderate-to-severe depression - a randomized controlled trial","volume":"136","author":"Kragh","year":"2017","journal-title":"Acta Psychiatr. Scand."},{"issue":"2","key":"10.1016\/j.jad.2019.09.078_bib0021","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/inm.12264","article-title":"Experiences of wake and light therapy in patients with depression: a qualitative study","volume":"26","author":"Kragh","year":"2017","journal-title":"Int. J. Ment. Health Nurs."},{"issue":"1","key":"10.1016\/j.jad.2019.09.078_bib0022","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1001\/jamapsychiatry.2015.2235","article-title":"Efficacy of bright light treatment, fluoxetine, and the combination in patients with nonseasonal major depressive disorder: a randomized clinical trial","volume":"73","author":"Lam","year":"2016","journal-title":"JAMA Psychiatry"},{"issue":"9","key":"10.1016\/j.jad.2019.09.078_bib0023","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.4088\/JCP.11m07625","article-title":"A 9-week randomized trial comparing a chronotherapeutic intervention (wake and light therapy) to exercise in major depressive disorder patients treated with duloxetine","volume":"73","author":"Martiny","year":"2012","journal-title":"J. Clin. Psychiatry"},{"issue":"6","key":"10.1016\/j.jad.2019.09.078_bib0024","doi-asserted-by":"crossref","first-page":"e67264","DOI":"10.1371\/journal.pone.0067264","article-title":"The day-to-day acute effect of wake therapy in patients with major depression using the HAM-D6 as primary outcome measure: results from a randomised controlled trial","volume":"8","author":"Martiny","year":"2013","journal-title":"PLoS ONE"},{"issue":"6","key":"10.1016\/j.jad.2019.09.078_bib0025","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1111\/acps.12402","article-title":"Maintained superiority of chronotherapy vs. exercise in a 20-week randomized follow-up trial in major depression","volume":"131","author":"Martiny","year":"2015","journal-title":"Acta Psychiatr. Scand."},{"issue":"3","key":"10.1016\/j.jad.2019.09.078_bib0026","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jad.2009.01.015","article-title":"A multistage chronobiologic intervention for the treatment of depression: a pilot study","volume":"116","author":"Moscovici","year":"2009","journal-title":"J. Affect. Disord."},{"issue":"1","key":"10.1016\/j.jad.2019.09.078_bib0027","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/0006-3223(95)00086-0","article-title":"Bright light therapy stabilizes the antidepressant effect of partial sleep deprivation","volume":"39","author":"Neumeister","year":"1996","journal-title":"Biol. Psychiatry"},{"issue":"2","key":"10.1016\/j.jad.2019.09.078_bib0028","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0165-1781(90)90077-I","article-title":"Prediction of the antidepressant response to total sleep deprivation by diurnal variation of mood","volume":"32","author":"Reinink","year":"1990","journal-title":"Psychiatry Res."},{"issue":"1\u20133","key":"10.1016\/j.jad.2019.09.078_bib0029","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jad.2009.01.029","article-title":"Meta-analysis of the placebo response in antidepressant trials","volume":"118","author":"Rief","year":"2009","journal-title":"J. Affect. Disord."},{"issue":"5","key":"10.1016\/j.jad.2019.09.078_bib0030","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s004060050092","article-title":"How to preserve the antidepressive effect of sleep deprivation: a comparison of sleep phase advance and sleep phase delay","volume":"249","author":"Riemann","year":"1999","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.jad.2019.09.078_bib0031","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jpsychires.2014.08.015","article-title":"Adjunctive triple chronotherapy (combined total sleep deprivation, sleep phase advance, and bright light therapy) rapidly improves mood and suicidality in suicidal depressed inpatients: an open label pilot study","volume":"59","author":"Sahlem","year":"2014","journal-title":"J. Psychiatr. Res."},{"issue":"2","key":"10.1016\/j.jad.2019.09.078_bib0032","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0165-0327(90)90015-Z","article-title":"Sleep deprivation in bright and dim light: antidepressant effects on major depressive disorder","volume":"19","author":"van den Burg","year":"1990","journal-title":"J. Affect. Disord."},{"issue":"2","key":"10.1016\/j.jad.2019.09.078_bib0033","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s00406-003-0408-7","article-title":"Is the antidepressive effect of sleep deprivation stabilized by a three day phase advance of the sleep period? A pilot study","volume":"253","author":"Voderholzer","year":"2003","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"issue":"1","key":"10.1016\/j.jad.2019.09.078_bib0034","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/0006-3223(93)90280-Q","article-title":"Sleep deprivation with consecutive sleep-phase advance therapy in patients with major depression: a pilot study","volume":"33","author":"Vollmann","year":"1993","journal-title":"Biol. Psychiatry"},{"issue":"2","key":"10.1016\/j.jad.2019.09.078_bib0035","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1600-0447.1985.tb02589.x","article-title":"Antidepressant effects of sleep deprivation in bright and dim light","volume":"72","author":"Wehr","year":"1985","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jad.2019.09.078_bib0036","article-title":"Perspectives in affective disorders: clocks and sleep","author":"Wirz-Justice","year":"2019","journal-title":"Eur. J. Neurosci."},{"issue":"4","key":"10.1016\/j.jad.2019.09.078_bib0037","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0006-3223(99)00125-0","article-title":"Sleep deprivation in depression: what do we know, where do we go?","volume":"46","author":"Wirz-Justice","year":"1999","journal-title":"Biol. Psychiatry"},{"issue":"3","key":"10.1016\/j.jad.2019.09.078_bib0038","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.biopsych.2009.02.018","article-title":"Rapid and sustained antidepressant response with sleep deprivation and chronotherapy in bipolar disorder","volume":"66","author":"Wu","year":"2009","journal-title":"Biol. Psychiatry"}],"container-title":["Journal of Affective Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032719309607?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0165032719309607?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T01:28:37Z","timestamp":1759022917000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0165032719309607"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":36,"alternative-id":["S0165032719309607"],"URL":"https:\/\/doi.org\/10.1016\/j.jad.2019.09.078","relation":{},"ISSN":["0165-0327"],"issn-type":[{"value":"0165-0327","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chronotherapy for the rapid treatment of depression: A meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Affective Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jad.2019.09.078","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}